Articles tagged with Dentistry
A new liposome-based method aims to kill periodontitis-causing leukotoxin while protecting immune cells, providing an alternative treatment for aggressive gum infections. The approach has potential applications against a range of bacteria and could help combat antibiotic resistance.
A growing connection between diabetes, oral health, and dementia highlights the importance of dental care and diabetes management as we age. Older adults with both poor oral health and diabetes experience accelerated cognitive decline, emphasizing the need for regular dental visits and adherence to diabetes treatment.
A Tohoku University study found that soft gingiva is more likely to cause inflammation, hindering the development of collagen fibers. This discovery has implications for the development of advanced biomaterials and microdevices to control local inflammation.
A research team developed a new dentine analogue material that can substitute extracted human teeth in laboratory-based mechanical and fatigue tests. The materials were tested for their mechanical strength, elastic modulus, indentation hardness, and fatigue behaviour, showing comparable results to those based on extracted human teeth.
Researchers used MRI scans and texture analysis to differentiate between two types of benign oral bone lesions, ameloblastomas and odontogenic keratocysts. The study found that certain pixel and voxel organizational parameters in the MRI images were statistically significant, enabling more accurate diagnosis and treatment planning.
Researchers at NYU College of Dentistry have developed a single score to describe the level of cytokines in saliva, which correlates with the severity of clinical gum inflammation. The study found that higher levels of cytokines in saliva match greater gum inflammation.
A NYU school dental program using silver diamine fluoride and sealants prevented 80% of cavities in a randomized trial. The study suggests an efficient and cost-effective approach to improving children's oral health through school-based care.
A Brazilian study found that early sugar consumption and interruption of breastfeeding are key factors contributing to dental caries in infants. Extended breastfeeding was shown to protect babies' teeth as long as they didn't receive sugary food, with the risk declining with falling sugar consumption.
A recent study published in the Journal of Dental Research compared ten pharmacological interventions for managing tooth extraction pain in adults. The study found that NSAIDs with or without acetaminophen result in better pain-related outcomes than opioids with or without acetaminophen.
A new study published in the Journal of Dental Research has found that heavy smokers with severe periodontitis do not receive any benefits from treatment. The study suggests that smoking cessation is crucial for effective treatment and may even worsen the disease during active treatment. The findings highlight the need to rethink pract...
A study by researchers from Okayama University found that Japanese university students' willingness to undergo regular dental check-ups is associated with their thoughts regarding the health-belief model and oral health behaviors. The study suggests that the perceived benefit of undergoing regular check-ups drives young students toward...
Researchers analyzed ancient teeth from Homo erectus and great apes to reveal annual cycles in tooth enamel, providing insights into their diets and seasonal food supplies. The study shows that humans and great apes had distinct dietary patterns, with humans exhibiting less pronounced peaks and lower Sr/Ca values.
Researchers have developed shortwave-infrared and thermal imaging techniques to accurately diagnose active dental caries. SWIR-based approach shows superior results in detecting lesions, while thermal imaging proves less effective.
A new jaw surgery technique, segmental mandibular advancement (SMA), has been shown to effectively treat moderate-to-severe Obstructive Sleep Apnea (OSA) in a pilot study. The procedure resulted in a 50% or more reduction in breathing disturbances at night for 58% of patients, with no signs of sleep apnea.
A study on extinct lemurs has found surprising similarities between ancient primate species and fossil humans. The 'monkey lemur' had novel anatomical features, including tooth chipping patterns similar to those of Neanderthals, suggesting a more complex diet than previously thought.
Researchers developed a customizable, strontium-loaded scaffold that promotes wound healing by stimulating gingival fibroblast activity. The scaffold increased cellular activity of isolated cells while showing minimal toxicity over four days.
Researchers found that activating the non-mutated form of P53 can change the fundamental makeup of cancer stem cells in mouse models of mucoepidermoid carcinoma. This new therapy approach shows promise for treating this lethal form of salivary gland cancer.
A study published in the Journal of Dentistry found that patients with unexplained brain abscesses were three times more likely to have oral bacteria present. The researchers also discovered significantly higher counts of Streptococcus anginosus, a bacterium linked to dental abscesses and infections in internal organs.
Researchers aim to understand how school-based sealant programs affect children's teeth in middle school, building on previous studies showing effectiveness in elementary schools. The goal is to estimate the impact of increasing middle-school-based sealant programs on children's oral health.
Researchers at Karolinska Institutet have identified the most common bacteria found in severe oral infections, shedding new light on the association between oral health and systemic diseases. The study found that certain bacterial infections can spread to other parts of the body, highlighting the importance of understanding the role of...
A University of Washington researcher claims that organizations like the World Health Organization and American Heart Association promoted high-carbohydrate diets over low-carb diets due to flawed nutritional guidelines. This shift led to increased use of fluoride to combat tooth decay, making it largely unnecessary.
A nationwide Australian study found no link between early exposure to fluoridated water and altered emotional, behavioral development, or executive functioning in adolescence. The study used data from Australia's National Child Oral Health Study and followed children aged 5-10 years for 7-8 years.
A study conducted at the University of Zurich has identified a key gene network responsible for severe tooth enamel defects. The researchers found that mutations in the Adam10 molecule lead to disorganization of ameloblasts and severe defects in both structure and mineral composition of enamel.
A new study led by NYU researchers has developed a topical gel that targets the succinate receptor to suppress inflammation, reduce bacterial imbalance, and prevent bone loss. The treatment has shown promise in reducing gum disease symptoms, including inflammation and tooth loss.
A new method for monitoring coral size and growth has been developed using dental scanning technology, reducing surveying time by 99%. This non-destructive approach allows scientists to measure thousands of tiny corals quickly and accurately without harming them, with the potential to expand large-scale monitoring of ocean health.
Researchers at Tohoku University have created a scaffold that supports the growth of new bone in large jaw defects in mice, bringing them closer to addressing the issue of aging jaw bone loss in humans. The technique uses a polylactic acid scaffold and has shown promise for treating large bone defects.
Researchers led by Osaka University found that Fusobacterium nucleatum produces polyamines through metabolic cross-feeding, creating favorable conditions for periodontal pathogens to grow and spread. This integration of a metabolic network within the oral microbiome may promote the development of periodontitis.
Researchers developed a novel biologically-inspired intraoral camera with a wide-angle insect eye structure, increasing field of view and resolving optical aberrations. The device provides multifunctional dental imaging, including high dynamic range, 3D depth, and autofluorescence, without discomfort or image blur.
Researchers develop a safe and effective way to whiten teeth without damaging enamel, breaking apart cavity-forming biofilms. The treatment uses a hydrogel activated by green light to kill 94% of bacteria in biofilms and prevent cavities from forming on teeth.
The University of Hong Kong's Faculty of Dentistry has developed an AI-powered approach to automate denture design, allowing for high accuracy and reducing treatment time. The new method uses a 3D Generative Adversarial Network (3D-GAN) algorithm to reconstruct the shape of natural teeth and generate prosthetic teeth.
Studies suggest a link between Fusobacterium nucleatum and Alzheimer's disease, with the bacteria generating systemic inflammation and exacerbating symptoms. Targeting the bacteria could slow periodontal disease progression and potentially slow Alzheimer's progression as well.
Researchers found that Treponema denticola, a periodontal pathogen, induces Alzheimer-like tau hyperphosphorylation in mice. The study showed that T. denticola promotes neuroinflammation and increases tau phosphorylation at specific sites.
This study found that consuming high amounts of free sugar between 18 months and 4 years increases the risk of dental caries at 4-6 years of age. The study, which analyzed data from over 863 children, also found that limiting free sugar intake reduced the risk of dental caries.
Women led a larger proportion of articles in top-cited samples and saw an increasing trend in publication rates over time. Gender disparities were observed across dental disciplines, countries, authorship positions, and time period.
A NJIT-led team has created an injectable hydrogel designed to recruit dental pulp stem cells and promote tissue growth in teeth after a root canal. The therapy mimics the body's natural growth factor signaling, promoting healing and regeneration of lost tooth pulp.
A study by researchers at UCSF found that e-cigarette use costs the US $15 billion annually in healthcare expenditures, with each user paying around $2,000 extra per year compared to non-users. The study, published in Tobacco Control, highlights the growing concern over health care costs associated with e-cigarette use.
A study published in Cell reveals that individuals with gum disease are more susceptible to developing arthritis due to alterations in immune cell precursors in the bone marrow. The researchers also found that this association may prompt a reconsideration of how bone marrow donors are selected.
Deleting or inhibiting a protein called lysine-specific demethylase 1 (LSD1) may curb the growth of oral squamous cell carcinoma tumors. The study found that disrupting LSD1 promotes anti-tumor immunity, which can help fight cancer. The discovery could lead to new and potentially more effective therapies for oral cancer patients.
Researchers at Tokyo University of Agriculture and Technology discovered that double-stranded RNA molecules can activate the immune system response leading to bone deterioration in gum disease. The study found that dsRNA triggers the differentiation of osteoclasts, cells responsible for breaking down bone, leading to increased bone ero...
Patients with a reported penicillin allergy have higher rates of dental implant failure. Alternative antibiotics prescribed during surgery also linked to increased failure rates. The study suggests that testing for actual allergies may improve outcomes.
Researchers tested if mothers' oral microbiome seeds a cariogenic community in children. They found that bacteria correlated between mothers and children were associated with lower risk of Early Childhood Caries (ECC). The study suggests poor maternal oral health may influence ECC risk through transmission of microbes.
Researchers created a dental tool that measures plaque acidity using an LED light and FDA-approved chemical dye, providing dentists with early warning signs of cavity development. The device can help limit the need for specific harmful bacteria tests and educate patients about sugar's impact on oral health.
A recent study found that sleep bruxism can lead to temporomandibular joint disorders due to increased mechanical loading. The research discovered that specific combinations of tooth shape and location during grinding significantly impact the risk of TMJ problems.
Oral health disparities persist despite improved overall health trends, disproportionately affecting marginalized groups. Research and policy initiatives are needed to make oral health care more affordable, accessible, and responsive to communities.
A series of studies by NYU researchers found that e-cigarette users have a distinct oral microbiome less healthy than nonsmokers but potentially healthier than cigarette smokers. The study also reveals altered immune responses, including increased inflammation and suppression of immune reactions.
A Swedish registry study found no increase in endocarditis cases among high-risk individuals since the removal of prophylactic antibiotics in dentistry. The study monitored over 76,000 high-risk individuals and 396,000 low-risk individuals from 2008 to 2018.
Researchers have designed a tiny and flat antenna for receiving and transmitting terahertz signals, enabling the miniaturization of THz devices. The new design integrates the antenna with the system, eliminating the need for bulky silicon lenses and reducing optical power required.
The study demonstrated that photodynamic therapy (PDT) using chlorin e-6 can effectively reduce bacterial plaque biofilms containing cariogenic microorganisms, including Streptococcus mutans. The treatment eliminated S. mutans and decreased total microorganisms by up to 3.7 units, with approximately 99% efficacy of antimicrobial activity.
A study by the University of Leeds found that changing drills from air-powered to electric drills can significantly reduce aerosol spray and create a safer environment for patients and dental teams. The research resulted in a 99.98% reduction in virus spread, potentially allowing millions more treatments to be carried out.
Researchers found a mussel-derived compound strengthens resin-dentin bond and improves its durability. The compound, N-(3,4-dihydroxyphenethy) methacrylamide (DMA), reduces nanoleakage and increases longevity of dental fillings.
Researchers created a model system to study the ultrasmall bacteria TM7 and found that they acquired a gene cluster encoding the arginine deiminase system, which helps them survive and multiply in the human oral cavity. This discovery suggests that TM7 may play a more protective role in oral health than previously thought.
Case studies show one in five children suffer from chalky tooth enamel, causing severe toothache and decay. Researchers from The D3 Group have found that albumin contamination blocks hardening of enamel on teeth growing inside the jaw, triggered by childhood illnesses.
A University of Otago study finds caries in wild primates occur at low frequencies but vary among groups, with distinct tooth patterns compared to fossil humans. The research provides a new perspective on human evolution and living primate behaviour.
A study of Edo-era Japanese skeletons reveals a prevalence of periodontal disease similar to modern times, with distinct bacterial species. Researchers analyzed dental calculus from 12 human skeletons and compared their oral microbiomes to modern samples, shedding light on the evolution of the oral microbiome.
The study found clear differences in bacterial community composition and functional profiles between healthy and diseased sites, with specific taxa associated with periodontal disease progression. The identification of key bacterial species and functions involved could help prevent permanent damage.
Researchers compared genetic expression profiles of canine acanthomatous ameloblastoma and human oral tumor ameloblastoma, finding similarities in molecular mutations. The study lays groundwork for potential translational medicine, as the dog model may represent a useful clinical model of the disease.
Researchers investigate the effect of local exhaust ventilation (LEV) devices on dental aerosols and droplets produced during procedures. LEV significantly reduces aerosol dispersion, with effects comparable to suction for ultrasonic scalers and substantial reductions for air-turbine handpieces.
A survey of US dentists found that an overwhelming majority believe nonsteroidal anti-inflammatory drug (NSAID)-acetaminophen combinations are as effective or more effective in managing dental pain as opioids. However, nearly half still prescribe opioids, highlighting a disconnect between their knowledge and prescribing habits.
Researchers at Graz University of Technology have developed a new production method for germanium-based photoinitiators, making them cheaper and more efficient. This enables their use in contact lenses, prostheses, and artificial human tissue, among other applications.
A new technique using in situ synchrotron X-ray microtomography has been developed to study the effects of acid on teeth. The technique enabled researchers to build clear 3D images of dentine's internal structure with sub-micrometre resolution, revealing that acid dissolves minerals at different rates in different structures of dentine.