Articles tagged with Dentistry
Barts Charity has awarded £6.5 million to Queen Mary University of London to transform its Charterhouse Square campus, featuring new labs, offices, and biorepositories for world-leading research in medicine and dentistry. The funding will support the expansion of research capacity and enhance collaboration among teams.
Researchers developed a method to measure 71 elements in water, beverages, and biological fluids simultaneously, providing a distinct 'fingerprint' to differentiate substances. This advancement has implications for fields like nutrition, ecology, climate science, and environmental health.
A new study from Western University identified the gene Panx1 as a key regulator of fat accumulation in mice. The research found that mice lacking Panx1 accumulated more fat and developed insulin resistance, increasing their risk for Type 2 Diabetes. Further studies are underway to explore the link between Panx1 and human obesity.
A study found that children generally lose their first baby tooth at six years old, and their emotions range from joy to fear. Parents of children who lost a milk tooth reported mostly positive feelings, with those whose previous dental visits were cavity-related experiencing fewer positive emotions.
This research article assesses two tools for cement crown retrieval, finding that the automatic tool improves reliability and efficiency. The study also reveals a significant difference in force patterns between the tools, with the compressed air-powered instrument producing sharper peak forces.
Researchers have developed a drug-free method for detecting and destroying the bacteria that cause dental plaque. The approach uses nanoparticles made of hafnium oxide to target and kill harmful bacteria, reducing biofilm burden and preventing conditions like cavities and cardiovascular disease.
Cynthia Pine, a renowned researcher at Queen Mary University of London, has received the IADR E.W. Borrow Memorial Award for her groundbreaking work on preventing childhood dental caries. Her research focuses on promoting oral health in disadvantaged communities and developing interventions to improve parents' key dental health behaviors.
A QUT-led project, funded by the Australian Research Council, is developing 'on-demand visible light degradable dental materials' to enable removal of bonded material without mechanical force. This innovation could make dental visits less painful and allow for more flexible dental applications.
Researchers have discovered a 400-million-year-old anti-viral protein that can potentlly block HIV, revealing an evolutionary arms race between the virus and the immune system. This ancient gene, HERC5, has been involved in a centuries-long battle for survival with viruses, resulting in sophisticated shields to block them.
A new study found that salivary RNA can regulate oral bacteria growth, influencing diseases such as periodontitis. The research discovered a channel of communication between RNA messengers and bacteria in the mouth.
A new clinical trial found that coaching patients with Chronic Kidney Disease (CKD) to drink more water did not slow down the decline of their kidney function. However, increased water intake did suppress antidiuretic hormone release and may be beneficial for those who are low-intake drinkers.
The study found that patients with unexplained atherosclerosis had significantly higher blood levels of toxic metabolites produced by intestinal bacteria. The researchers suggest that the gut microbiome plays an important role in an individual's risk for atherosclerosis, opening the door for new treatment options.
Research reveals strong connections between longitudinal beverage intakes and adolescent caries experience, with higher sugar-sweetened beverage consumption and lower fluoride intakes leading to increased caries risk. The study emphasizes the importance of adjusting for preventive factors such as brushing frequency in future studies.
A study at the University of Minnesota School of Dentistry found a significant decrease in opioid prescriptions after implementing an opioid prescribing protocol. The analysis showed a 47.1% reduction in total opioid prescriptions and tablets per prescription written.
J. Bernard Machen, a renowned educator and researcher, has been awarded the AADR Honorary Membership for his dedication to public health and dental research. The American Association for Dental Research (AADR) recognized Machen's innovative leadership in dental education and unwavering support for research and discovery science.
A team of researchers has developed an open-source, clinically validated template for a 3D printed stethoscope that can be created using recycled plastic and costs less than $3 to produce. The device has been shown to have the same acoustic quality as premium brand stethoscopes.
Researchers at NYU Dentistry have adapted an HIV test to create a rapid diagnostic test for Zika virus using saliva. The new test can detect both nucleic acids and antibodies of the virus in a fraction of the time of current commercial tests, producing results in minutes instead of hours or days.
A major study found a significant increase in the number of X-rays given to patients when dentists were paid on a 'fee-for-service' basis, compared to fixed salaries. This increase was most pronounced when patients were exempt from charges.
Researchers at U of T have designed a new antimicrobial material to minimize recurrent caries under fillings, affecting 100 million patients annually. The novel material packs 50 times more bacteria-fighting drugs than traditional options, offering a potential solution to this common dental problem.
Researchers at Western University have discovered a unique neurobiological pathway triggered by head trauma that underlies both Chronic Traumatic Encephalopathy (CTE) and Lou Gehrig's disease. The study, published in the January 2018 issue of Neurology, identifies a common link between CTE and ALS-related cognitive impairment.
A study highlights the need for better training and education in the dental community to discuss HPV prevention methods with patients. Most dentists don't address HPV-related oropharyngeal cancers due to lack of knowledge and communication skills.
A new study published in Scientific Reports found that monocyte chemoattractant protein-1 (MCP-1) plays a crucial role in bone loss responses to parathyroid hormone (PTH) in hyperparathyroidism. Elevated MCP-1 levels have been correlated with elevated serum PTH levels, and its presence may serve as a marker for PTH's effects in humans.
A new study found that elevated oral pathogens and decreased bacterial diversity are associated with precancerous stomach cancer lesions. The researchers suggest that treating chronic periodontal disease and controlling pathogen infections may help prevent stomach cancer.
A new study published in Frontiers in Medicine found that patients who drink alcohol or smoke are more likely to experience dental filling failure. Genetic differences were also discovered to be associated with increased filling failure rates, suggesting personalized treatments could lead to improved outcomes.
Researchers have found that young hockey players who suffered concussions may still exhibit white matter changes in the brain months after being cleared to return to play. Advanced MRI techniques revealed prolonged abnormalities in terms of brain structure and function, suggesting potential long-term consequences.
Researchers at UCLA School of Dentistry used nanodiamonds embedded with biomaterials to protect disinfected root canals, resulting in improved tissue healing and no infection in three patients. The study confirms the immense promise of using nanodiamonds for overcoming barriers in various medical procedures.
A study of over 1,000 Chinese individuals found a direct correlation between health and the microbes in their intestine. The researchers discovered that the overall microbiota composition of the healthy elderly group was similar to that of people decades younger.
Researchers develop microneedle technology to increase topical anesthesia penetration, reducing patient discomfort during dental procedures. The method has shown promising results in preliminary tests, with patients tolerating deeper injections.
Researchers develop heat-treated magnesium alloy that outperforms titanium in implant applications, promoting bone growth and stability while avoiding complications like infection and corrosion. The T-5 alloy shows superior mechanical properties, lower degradation rates, and limited risks of rejection or infection.
Dr. Yu Zhang received nearly $3.7 million from the NIH's NIDCR to develop strong yet natural-looking materials for restorative dentistry. His research aims to create aesthetic, strong, and abrasion-resistant materials by developing new zirconia-based ceramics.
Researchers at NYU Dentistry have identified two proteins that regulate the formation of pearls, a process that could lead to the development of fracture-resistant materials. These materials could be used in dental implants, aerospace applications, or energy transmission.
Researchers at NYU Langone Health's main hospital during Superstorm Sandy found that communication and social support were critical in connecting nurses with others during the crisis. The study also calls for more education and planning for future disasters, including training on power loss and 'all hazards' approaches.
A new dental imaging method using squid ink combines light and ultrasound for a comprehensive and accurate examination of gums without pain or discomfort. This non-invasive approach enables dentists to create detailed maps of gum pocket depths, surpassing the conventional method's limitations.
Researchers at NYU Bluestone Center found that dopamine produced by melanocytes contributes to differences in skin responsiveness to heat and mechanical stimuli. This discovery may lead to more targeted and personalized pain treatment, as skin pigmentation affects sensitivity to temperature and pressure.
A University of Michigan professor analyzed sailors' mouths for clues in the 1845 Franklin expedition disaster. The study found that tuberculosis resulting in adrenal insufficiency, or Addison's disease, likely contributed to the crew's deaths.
Researchers found specific early immune response signatures that developed into widespread activation after traumatic injury, leading to serious organ failure. The study provides insights into potential intervention strategies, including diagnostics, clinical trials, precision medicine, and novel therapies.
Researchers at NYU College of Dentistry have identified succinate as a promising target to prevent bone fractures in people with type 2 diabetes. The study found that hyperglycemic mice had significantly higher levels of succinate, leading to more fragile bones and increased risk of fractures.
Researchers at OHSU developed a process to engineer new blood vessels in teeth, creating better long-term outcomes for patients. This innovation eliminates the need for synthetic biomaterials and restores biological response, potentially leading to improved tooth survival rates.
Researchers from NYU Dentistry studied a sea urchin protein that forms hydrogels, capturing mineral nanoparticles and organizing them into crystalline bricks. The protein, rSpSM50, induces fracture resistance and enables the creation of tunable fracture-resistant materials.
Researchers at the University of Illinois Chicago have discovered a natural compound in grape seed extract that can strengthen dentin and increase the life of resin fillings. The study found that the extract can make composite-resin fillings stronger, allowing them to last longer.
Acoustic habituation is a common form of sensory filtering that allows the brain to block out extraneous sounds and focus on important information. The Western-led research identified the underlying molecular mechanism that controls this ability, which can be regulated with drugs in animal models.
A new approach using a combination of silver, titanium oxide and hydroxyapatite nanocoatings successfully inhibited bacterial growth on dental implants by 97.5%, reducing the risk of peri-implantitis. The findings have great potential for increased patient comfort and satisfaction, as well as reduced costs.
Researchers at NYU Dentistry are studying calcium control in dental enamel to develop improved strategies for preventing and treating dental caries. The goal is to understand how changes in calcium levels affect enamel mineralization and develop clinical techniques to replicate these processes.
Researchers have developed a new enzyme called TevCas9, which cuts DNA in two places instead of one, making it more difficult for DNA-repair to regenerate the site of the cut. This modification shows promise at being more specific in targeting genes and less likely to cause off-target effects.
The study highlights the lack of research on bite-mark identification and its low validity. Forensic dentists' claims of unique dental signatures are unfounded, leading to wrongful convictions. Recent DNA exonerations support the rejection of bite-mark identifications as reliable evidence.
New York University College of Dentistry has received a grant to investigate potential new compounds for treating osteoporosis. The researchers aim to understand the molecular mechanisms of parathyroid hormone-a related protein and its analogs to develop better-tolerated treatments.
A University of Rochester Medical Center study reveals that e-cigarettes can cause damage to gums and teeth, similar to conventional cigarettes. The study found that flavoring chemicals play a role in damaging cells in the mouth, and nicotine contributes to gum disease.
A new genetic testing method, LipidSeq, has been developed to identify a genetic basis for high-cholesterol in almost 70% of targeted patient populations. The method uses next-generation sequencing technology to pinpoint specific areas of a person's DNA and provides a more cost-effective way to diagnose genetic forms of high-cholesterol.
A new imaging device uses long-wavelength infrared imaging to detect small thermal radiation emitted from dental caries, allowing for earlier diagnosis and potential reversal. The tool has the benefits of being noncontact, noninvasive, and low-cost, with great potential as a commercially viable diagnostic imaging device.
A new dental school will be established in Texas with a significant impact on oral health care in the region. The school will address a severe shortage of dentists in El Paso County, where there is only one dentist for every 5,000 residents.
The research aims to define the core molecular components of the Permeability Transition, a phenomenon that causes cell death during stress conditions. By understanding this process, novel treatment strategies can be designed to target specific non-proteinaceous components and prevent mPTP opening.
A systematic review of existing research suggests that physical activity could divert attention away from addiction, build confidence, and improve mood. The study aims to provide practical information on the effectiveness of physical activity as an alternative approach to treating alcohol and substance use disorders.
Researchers used dentistry techniques to analyze fossil and modern teeth, finding similarities between ancient walruses and modern pinnipeds. The findings suggest that the ancient walrus was unlikely to feed on large prey, contradicting previous claims of a 'killer walrus' diet.
The NYU College of Dentistry has received a $1.6 million NIH grant to investigate the impact of e-cigarette aerosol mixtures on oral health. Researchers will examine the modulation of the oral microenvironment by e-cig aerosols and assess periodontal disease risk.
Dental drill fragments made of bio-incompatible materials are found in teeth and under fillings, posing a potential risk to patients. Further studies are needed to determine the extent of this biohazard.
A University of Alberta researcher has been awarded a $2.1 million grant to study the molecular pathways of cancer therapies causing heart complications. The goal is to develop new, novel therapies to prevent cardiotoxicity while maintaining cancer treatment effectiveness.
A recent study by researchers at Kyushu Dental University found a significant evidence-practice gap for sealant application among Japanese dentists. The findings suggest that dentists' beliefs about the effectiveness of caries risk assessment are strongly associated with their recommendation of dental sealants.
Researchers have identified the formation of tiny bubbles around the head of ultrasonic scalers as crucial to the cleaning process. The study's findings aim to develop new instrument designs that maximize cavitation to improve plaque removal, reducing pain and increasing effectiveness.
A UK project will provide an estimated size of the lesbian, gay and bisexual community in England, enabling Public Health England to address their health needs. The research team will develop a robust method to measure the LGB population size on an ongoing basis.
Researchers discovered that blood plasma metabolites and RNA from pigs oscillate on a five-day rhythm, mirroring a corresponding rhythm in tooth enamel. This finding provides insight into biological processes regulating growth and body size, and may be key to understanding species' life history evolution.