Articles tagged with Dentistry
NYU College of Dentistry has been awarded a $1.9 million NIH grant to study the molecular mechanisms underlying mitochondrial permeability transition, a phenomenon that causes tissue damage during strokes and heart attacks. The research aims to develop new drugs that can protect against cell death and tissue damage.
Researchers at Imperial College London and King's College London suggest that dentists avoid using drills with air and water mixtures and carefully select drill rotation speeds to reduce aerosol generation. This approach can produce 60 times fewer aerosol droplets, allowing for safer dental procedures and increased patient access
The COVID-19 pandemic has underscored the importance of defining essential oral healthcare. A layered approach to essential oral healthcare allows for categorization and prioritization with available resources in mind, recognizing basic oral healthcare as an integral component of a healthcare system's essential services. The Internatio...
A study by dentists from RUDN University found that a change in the dominant side of chewing can cause early deterioration of dental implants. The researchers monitored 64 patients with dental implants and discovered that those who changed their chewing habits after surgery experienced more bone tissue formation pathologies.
A new study by NYU College of Dentistry found that half of US dentists experienced verbal or reputational aggression in the past year, while nearly a quarter endured physical aggression. The rates of patient aggression toward dentists are high and comparable with those reported in other health care settings.
A team of scientists at the University of Toronto has discovered the mechanism linking periodontal disease to other inflammatory conditions. The study found that neutrophil immune cell activity is the key factor connecting gum disease to heart disease, cancer, and other inflammatory conditions.
A team of dentists from RUDN University presented a new classification system for root canal shape changes, which can vary depending on the tooth part and patient age. The study used CT scans of 300 patients and identified four groups of shape changes to help dentists choose proper tools and treatment methods.
Researchers discovered that food-grade polymers can completely eliminate aerosolization of saliva droplets in dental settings. The polymers' viscoelastic properties restrict water aerosolization by creating snakelike strands that pull droplets back, preventing aerosolization.
Researchers at University of Saskatchewan are developing a unique saliva-based test to detect SARS-CoV-2 peptides in saliva, which is expected to be more sensitive, less invasive, and less expensive than current methods. The test aims to detect mild or asymptomatic COVID-19 cases and will be available by March 2021.
A University of Toronto team has been awarded a $1.5 million grant to study the impact of cannabis use on Indigenous oral health in Canada. The study will gather first evidence of the effects of cannabis on Indigenous populations, working in partnership with communities and public health authorities.
A new deep learning model accurately localises the exact location of mandibular canals in lower jaws, making dental implant operations faster and more efficient. The model surpasses existing methods, such as statistical shape models, and performs equally fast and accurately every time.
A new study published in Scientific Reports found that teeth contain annual layers, or cementum bands, that record an individual's life experiences, including reproduction and menopause. The research uses microscopic examination to reveal connections between tooth formation and other life stages.
Researchers found that patients prescribed opioids after tooth extraction reported worse pain, and half of prescribed opioids remained unused. The study suggests that alternatives such as nonsteroidal anti-inflammatory drugs or acetaminophen control pain better and improve patient satisfaction.
A molecule found in oranges, called nobiletin, has been shown to drastically reduce obesity in mice by reducing insulin resistance and blood fats. Researchers are now exploring its potential as a treatment for human obesity and related diseases, including heart disease and diabetes.
A new study led by NYU College of Dentistry researchers found that vaping alters the oral microbiome, making users more prone to inflammation and infection. E-cigarette users were found to have different bacteria in their mouths compared to smokers and non-smokers.
Researchers at NYU College of Dentistry discovered that excessive fluoride causes dental fluorosis by altering calcium signaling, mitochondrial function, and gene expression in tooth enamel cells. This understanding provides a promising mechanistic view of how fluorosis arises.
A new study by West Virginia University researchers links higher concentrations of perfluorodecanoic acid in children's blood to increased tooth decay rates. The chemical, found in some drinking water systems, may disrupt the healthy development of enamel, making teeth more susceptible to cavities.
A new study found that over half of US opioid prescriptions for dental procedures exceeded the recommended 3-day supply, with nearly 1/3 of patients receiving more powerful opioids than needed. The study suggests that improving guidelines and education for dentists can help reduce overprescription.
A new study suggests that roughly half of opioid prescriptions written by dentists in the US exceed federal guidelines for pain management. Dental procedures like extractions can lead to significant pain, and researchers found that some dentists are overprescribing opioids as a result.
A new study published in Scientific Reports reveals that regular cannabis use during pregnancy can lead to reduced birth weight by up to 8% and decreased brain and liver growth. The researchers used a rat model and human placental cells to demonstrate the impact of THC on fetal development.
New research from Western University found that people with a stroke are 20-25 times more likely to have a major cardiovascular event within 30 days. The risk persists even after one year, with men and women still experiencing twice the risk of heart complications compared to those without a stroke.
A recent study found that oral infections are not linked to increased risk of death or serious infection after stem cell transplantation. The researchers suggest that conservative dental treatment may be sufficient for patients with asymptomatic dental infections, and radical treatment is only necessary in specific cases.
The International Association for Dental Research (IADR) celebrates its Centennial issue, highlighting the history of women's contributions to dental research. The issue discusses unconscious biases, glass ceilings, and strategies to promote women in STEMM fields.
The Journal of Dental Research Centennial article 'The Evolution of Neuroscience as a Research Field Relevant to Dentistry' highlights novel insights gained through neuroscience research into pain, sensorimotor disorders and neural pathways. The study reveals the clinical relevance of these findings for diagnosis and management of diso...
The article highlights the importance of behavioral sciences in dentistry, expanding the understanding of oral health beyond 'disease' to a broader concept. Recent studies have shown promising results in employing cognitive behavioral therapy for managing dental anxiety and pain, as well as addressing oral health inequalities.
Researchers developed a novel nanoparticle delivery method to treat pain, using a non-opioid drug that previously failed clinical trials. The approach successfully treated pain in mice and rats with improved efficacy and duration of action.
The discovery of osseointegration has led to high clinical performance of oral implants, but peri-implant soft tissue complications can jeopardize osseointegration. Early intervention in situations with peri-implant mucositis is crucial for preventing peri-implantitis.
The International Association for Dental Research celebrates its centennial with a special article highlighting key successes in tooth bioengineering and regenerative dentistry. Researchers discuss promising developments, including whole tooth tissue engineering and the potential for improved dental repair therapies.
A new study from Western University found that tRNA gene mutations can cause misreading of the genetic code, leading to protein malfunction. Researchers discovered an average of 66 variants in tRNA genes among individuals in London, Ontario, suggesting a potential link between these mutations and human diseases such as Alzheimer's.
Researchers at Western University and Lawson Health Research Institute have found that senescent cells contribute to the growth of ascending aortic aneurysms. The study suggests that therapies targeting these cells could prevent or slow down aneurysm growth, potentially saving lives.
Dagmar Else Slot, a renowned researcher, has been awarded the 2019 Young Investigator Award by the International Association for Dental Research (IADR) for her groundbreaking work on oral infections and inflammation. She is recognized for her contributions to evidence-based dentistry and prevention of periodontal diseases.
A NIOSH-funded study is assessing how dental professionals come into contact with vapors, gases, and airborne dusts in clinics. The researchers will measure the size and concentration of particulates in real-time during common dental procedures.
Researchers at the University of Toronto have discovered two distinct neutrophil states in blood, which vary depending on patient health and infection status. These findings may lead to new models for disease detection and monitoring, such as tracking primed neutrophils to predict inflammatory diseases.
Dentist Sharukh S. Khajotia is investigating decay and tooth-colored filling materials to extend their lifespan, potentially saving patients' tooth structure and reducing healthcare costs.
A study led by NYU Dentistry researchers reveals that a mutation in the ORAI1 gene causes calcium deficiency in enamel cells, leading to defective dental enamel mineralization. The study identified ORAI1 as the dominant protein for calcium influx and provided insights into the mechanisms by which calcium affects enamel cell function.
The new technology provides a 360-degree, three-dimensional view of surgical tools and surrounding tissue for more precise needle placement. This allows for improved dose pattern distribution to the tumour and surrounding tissue, reducing complication rates.
A new dental filling material made with thiourethane could significantly extend its lifespan, reducing the need for frequent fillings and related complications. The material has been shown to be two times more resistant to breakage than standard fillings.
Researchers are using tobacco plants as 'green bioreactors' to produce large quantities of the human protein Interleukin 37, which has powerful anti-inflammatory and immune-suppressing properties. The production method is more affordable than current methods, offering potential for treating a range of inflammatory disorders.
Barts Charity is funding a £6 million initiative to launch the 'Rising Stars' lectureship programme, supporting 16 young scientists in their careers. The programme aims to establish a new generation of researchers who will shape the next decade of medical research.
The study found that non-US-born healthcare professionals made up a significant proportion of the workforce, with 16.6% not born in the US and 4.6% being noncitizens. Non-US-born professionals were most prevalent in certain fields like medicine, dentistry, and nursing.
Queen Mary University of London has received £6.5 million in funding from Barts Charity to develop a new teaching lab, Cell Culture Labs, Tissue Bank Lab, Mass Spec Lab, Microscopy Lab, and office spaces at its Charterhouse Square campus. The investment will enhance the school's capacity to host up to 100 new appointments over four years.
Barts Charity has awarded £6.5 million to Queen Mary University of London to transform its Charterhouse Square campus, featuring new labs, offices, and biorepositories for world-leading research in medicine and dentistry. The funding will support the expansion of research capacity and enhance collaboration among teams.
A Stanford University School of Medicine study found that teens and young adults who receive their initial opioid prescriptions from dentists are at increased risk for opioid addiction in the following year. The study, which examined nearly 15,000 patients, found that those who received dental opioid prescriptions were more likely to c...
Researchers developed a method to measure 71 elements in water, beverages, and biological fluids simultaneously, providing a distinct 'fingerprint' to differentiate substances. This advancement has implications for fields like nutrition, ecology, climate science, and environmental health.
A new study from Western University identified the gene Panx1 as a key regulator of fat accumulation in mice. The research found that mice lacking Panx1 accumulated more fat and developed insulin resistance, increasing their risk for Type 2 Diabetes. Further studies are underway to explore the link between Panx1 and human obesity.
A study found that children generally lose their first baby tooth at six years old, and their emotions range from joy to fear. Parents of children who lost a milk tooth reported mostly positive feelings, with those whose previous dental visits were cavity-related experiencing fewer positive emotions.
This research article assesses two tools for cement crown retrieval, finding that the automatic tool improves reliability and efficiency. The study also reveals a significant difference in force patterns between the tools, with the compressed air-powered instrument producing sharper peak forces.
Researchers have developed a drug-free method for detecting and destroying the bacteria that cause dental plaque. The approach uses nanoparticles made of hafnium oxide to target and kill harmful bacteria, reducing biofilm burden and preventing conditions like cavities and cardiovascular disease.
Cynthia Pine, a renowned researcher at Queen Mary University of London, has received the IADR E.W. Borrow Memorial Award for her groundbreaking work on preventing childhood dental caries. Her research focuses on promoting oral health in disadvantaged communities and developing interventions to improve parents' key dental health behaviors.
A QUT-led project, funded by the Australian Research Council, is developing 'on-demand visible light degradable dental materials' to enable removal of bonded material without mechanical force. This innovation could make dental visits less painful and allow for more flexible dental applications.
Researchers have discovered a 400-million-year-old anti-viral protein that can potentlly block HIV, revealing an evolutionary arms race between the virus and the immune system. This ancient gene, HERC5, has been involved in a centuries-long battle for survival with viruses, resulting in sophisticated shields to block them.
A new clinical trial found that coaching patients with Chronic Kidney Disease (CKD) to drink more water did not slow down the decline of their kidney function. However, increased water intake did suppress antidiuretic hormone release and may be beneficial for those who are low-intake drinkers.
A new study found that salivary RNA can regulate oral bacteria growth, influencing diseases such as periodontitis. The research discovered a channel of communication between RNA messengers and bacteria in the mouth.
The study found that patients with unexplained atherosclerosis had significantly higher blood levels of toxic metabolites produced by intestinal bacteria. The researchers suggest that the gut microbiome plays an important role in an individual's risk for atherosclerosis, opening the door for new treatment options.
Research reveals strong connections between longitudinal beverage intakes and adolescent caries experience, with higher sugar-sweetened beverage consumption and lower fluoride intakes leading to increased caries risk. The study emphasizes the importance of adjusting for preventive factors such as brushing frequency in future studies.
A study at the University of Minnesota School of Dentistry found a significant decrease in opioid prescriptions after implementing an opioid prescribing protocol. The analysis showed a 47.1% reduction in total opioid prescriptions and tablets per prescription written.
J. Bernard Machen, a renowned educator and researcher, has been awarded the AADR Honorary Membership for his dedication to public health and dental research. The American Association for Dental Research (AADR) recognized Machen's innovative leadership in dental education and unwavering support for research and discovery science.
A team of researchers has developed an open-source, clinically validated template for a 3D printed stethoscope that can be created using recycled plastic and costs less than $3 to produce. The device has been shown to have the same acoustic quality as premium brand stethoscopes.
Researchers at NYU Dentistry have adapted an HIV test to create a rapid diagnostic test for Zika virus using saliva. The new test can detect both nucleic acids and antibodies of the virus in a fraction of the time of current commercial tests, producing results in minutes instead of hours or days.
A major study found a significant increase in the number of X-rays given to patients when dentists were paid on a 'fee-for-service' basis, compared to fixed salaries. This increase was most pronounced when patients were exempt from charges.