Articles tagged with Dentistry
A University of Michigan professor analyzed sailors' mouths for clues in the 1845 Franklin expedition disaster. The study found that tuberculosis resulting in adrenal insufficiency, or Addison's disease, likely contributed to the crew's deaths.
Researchers found specific early immune response signatures that developed into widespread activation after traumatic injury, leading to serious organ failure. The study provides insights into potential intervention strategies, including diagnostics, clinical trials, precision medicine, and novel therapies.
Researchers at NYU College of Dentistry have identified succinate as a promising target to prevent bone fractures in people with type 2 diabetes. The study found that hyperglycemic mice had significantly higher levels of succinate, leading to more fragile bones and increased risk of fractures.
Researchers at OHSU developed a process to engineer new blood vessels in teeth, creating better long-term outcomes for patients. This innovation eliminates the need for synthetic biomaterials and restores biological response, potentially leading to improved tooth survival rates.
Researchers from NYU Dentistry studied a sea urchin protein that forms hydrogels, capturing mineral nanoparticles and organizing them into crystalline bricks. The protein, rSpSM50, induces fracture resistance and enables the creation of tunable fracture-resistant materials.
Researchers at the University of Illinois Chicago have discovered a natural compound in grape seed extract that can strengthen dentin and increase the life of resin fillings. The study found that the extract can make composite-resin fillings stronger, allowing them to last longer.
Acoustic habituation is a common form of sensory filtering that allows the brain to block out extraneous sounds and focus on important information. The Western-led research identified the underlying molecular mechanism that controls this ability, which can be regulated with drugs in animal models.
A new approach using a combination of silver, titanium oxide and hydroxyapatite nanocoatings successfully inhibited bacterial growth on dental implants by 97.5%, reducing the risk of peri-implantitis. The findings have great potential for increased patient comfort and satisfaction, as well as reduced costs.
Researchers at NYU Dentistry are studying calcium control in dental enamel to develop improved strategies for preventing and treating dental caries. The goal is to understand how changes in calcium levels affect enamel mineralization and develop clinical techniques to replicate these processes.
Researchers have developed a new enzyme called TevCas9, which cuts DNA in two places instead of one, making it more difficult for DNA-repair to regenerate the site of the cut. This modification shows promise at being more specific in targeting genes and less likely to cause off-target effects.
The study highlights the lack of research on bite-mark identification and its low validity. Forensic dentists' claims of unique dental signatures are unfounded, leading to wrongful convictions. Recent DNA exonerations support the rejection of bite-mark identifications as reliable evidence.
New York University College of Dentistry has received a grant to investigate potential new compounds for treating osteoporosis. The researchers aim to understand the molecular mechanisms of parathyroid hormone-a related protein and its analogs to develop better-tolerated treatments.
A University of Rochester Medical Center study reveals that e-cigarettes can cause damage to gums and teeth, similar to conventional cigarettes. The study found that flavoring chemicals play a role in damaging cells in the mouth, and nicotine contributes to gum disease.
A new genetic testing method, LipidSeq, has been developed to identify a genetic basis for high-cholesterol in almost 70% of targeted patient populations. The method uses next-generation sequencing technology to pinpoint specific areas of a person's DNA and provides a more cost-effective way to diagnose genetic forms of high-cholesterol.
A new imaging device uses long-wavelength infrared imaging to detect small thermal radiation emitted from dental caries, allowing for earlier diagnosis and potential reversal. The tool has the benefits of being noncontact, noninvasive, and low-cost, with great potential as a commercially viable diagnostic imaging device.
A new dental school will be established in Texas with a significant impact on oral health care in the region. The school will address a severe shortage of dentists in El Paso County, where there is only one dentist for every 5,000 residents.
The research aims to define the core molecular components of the Permeability Transition, a phenomenon that causes cell death during stress conditions. By understanding this process, novel treatment strategies can be designed to target specific non-proteinaceous components and prevent mPTP opening.
A systematic review of existing research suggests that physical activity could divert attention away from addiction, build confidence, and improve mood. The study aims to provide practical information on the effectiveness of physical activity as an alternative approach to treating alcohol and substance use disorders.
The NYU College of Dentistry has received a $1.6 million NIH grant to investigate the impact of e-cigarette aerosol mixtures on oral health. Researchers will examine the modulation of the oral microenvironment by e-cig aerosols and assess periodontal disease risk.
Researchers used dentistry techniques to analyze fossil and modern teeth, finding similarities between ancient walruses and modern pinnipeds. The findings suggest that the ancient walrus was unlikely to feed on large prey, contradicting previous claims of a 'killer walrus' diet.
Dental drill fragments made of bio-incompatible materials are found in teeth and under fillings, posing a potential risk to patients. Further studies are needed to determine the extent of this biohazard.
A University of Alberta researcher has been awarded a $2.1 million grant to study the molecular pathways of cancer therapies causing heart complications. The goal is to develop new, novel therapies to prevent cardiotoxicity while maintaining cancer treatment effectiveness.
A recent study by researchers at Kyushu Dental University found a significant evidence-practice gap for sealant application among Japanese dentists. The findings suggest that dentists' beliefs about the effectiveness of caries risk assessment are strongly associated with their recommendation of dental sealants.
Researchers have identified the formation of tiny bubbles around the head of ultrasonic scalers as crucial to the cleaning process. The study's findings aim to develop new instrument designs that maximize cavitation to improve plaque removal, reducing pain and increasing effectiveness.
A UK project will provide an estimated size of the lesbian, gay and bisexual community in England, enabling Public Health England to address their health needs. The research team will develop a robust method to measure the LGB population size on an ongoing basis.
Researchers discovered that blood plasma metabolites and RNA from pigs oscillate on a five-day rhythm, mirroring a corresponding rhythm in tooth enamel. This finding provides insight into biological processes regulating growth and body size, and may be key to understanding species' life history evolution.
The American College of Prosthodontists has published its first national clinical practice guidelines, emphasizing the importance of routine dental examinations every 6 months to maintain restored teeth and implants. The guidelines also highlight the need for continuous education on individualized at-home maintenance regimens.
Researchers at the University of Alberta have discovered a potential new pathway for treating multiple sclerosis by suppressing granzyme B, an enzyme that damages nerve cells. By inhibiting granzyme B with serpina3n, they found significant reduction in MS symptoms in human cells and pre-clinical models.
A NYU research team led by Dr. Rodrigo Lacruz has discovered the mechanism of calcium transport essential for dental enamel formation. The study found that CRAC channels play a critical role in controlling calcium uptake, which is necessary for enamel crystal growth.
Researchers have created a new material combining nanodiamonds, gutta-percha, and amoxicillin to strengthen root canal fillings and kill bacteria. The material shows promise in preventing re-infections and improving current therapies.
Brazilian scientists review advances in nanodentistry, exploring how nanoparticles can improve dental materials, prevent oral diseases, and create wearable toothpaste. However, safety and cost concerns hinder the adoption of these new technologies.
Researchers developed a new material fortified with nanodiamonds that can combat bacterial infections in teeth. The nanodiamond-enhanced gutta percha showed promise in preventing residual infection and promoting healthy tooth regeneration.
Dental researchers at Plymouth University have won several prestigious awards, including the Unilever poster prize and a commendation in the Senior Colgate competition. The university's strong research culture was also recognized, with a notable increase in attention from dental research experts.
Researchers at the University of Toronto found that an abnormal immune response between neutrophils and cancer cells drives oral cancer metastasis. This connection may lead to targeted immunotherapies to shut down the abnormal response.
A new study will examine the relationship between family stress, parenting behaviors, and early childhood cavities in children aged 1-3 years. The two-year study aims to identify factors that contribute to the development of Early Childhood Caries and improve prevention strategies.
Researchers at Queen's University Belfast have developed a new treatment that prevents Klebsiella pneumonia from blocking the body's natural defences. The therapy uses an inhibitor to stop the superbug from taking over a protein in white blood cells, making it capable of killing the infection.
Researchers at the University of Montreal have discovered that astrocytes control the pattern of neuronal electrical activity, determining functions such as chewing, locomotion, and respiration. The study reveals a mechanism by which astrocytes regulate calcium levels, leading to changes in neural function.
Researchers at the University of Toronto's Faculty of Dentistry have identified Adseverin as a key driver behind bone loss associated with periodontitis and other inflammatory diseases. The protein plays a critical role in generating larger osteoclasts, leading to rapid bone loss.
Lorne Tyrrell, a renowned virologist, has been awarded the 2015 Killam Prize for Health Sciences for his groundbreaking work on viral hepatitis. His research has led to the development of an effective treatment for hepatitis B and is being continued in efforts to create a vaccine for hepatitis C.
A new study from the University of Alberta's Faculty of Medicine & Dentistry found that keeping a pain diary can have unintended consequences on patient recovery. Patients who kept diaries had slower recovery rates compared to those who did not.
A study investigated how GPs negotiate sick notes with patients presenting with physical vs. mental health issues. The results showed stronger doctor endorsement and patient entitlement for physical symptoms, but weaker endorsement for mental health issues.
Researchers from UAlberta found that nighttime leg cramps peak in summer and burden doubles in the season. The study suggests that patients can stop taking quinine during colder months when symptoms worsen.
Researchers at UCLA and J. Craig Venter Institute discovered a signaling interaction between TM7x and Actinomyces odontolyticus, which causes mucosal inflammation. The study sheds light on the biological importance of TM7x and its potential roles in chronic diseases.
A study of over 2,700 Australians found that many people with tooth loss do not need dentures as long as they have a sufficient number and type of remaining teeth. The researchers suggest allocating resources to prevent further tooth loss, diagnostic services, and follow-up care instead.
A University of Iowa study found that homemade strawberry-baking soda remedies have no effect on teeth whitening. In contrast, over-the-counter products, professional whitening, and prescribed whitening products produced discernible whitening results.
A study in the Journal of Consumer Research found that consumers can extend good experiences and shorten bad ones by categorizing them. By grouping events together, individuals can make pleasurable experiences feel longer and unpleasant ones feel shorter.
UTHealth researchers discovered that hollow-head toothbrushes harbor up to 3,000 times more bacteria than their solid-head counterparts. The study's findings highlight the importance of choosing a solid-head power toothbrush to minimize bacterial growth and prevent disease transmission.
A new study found that over 80% of oral health patients are willing to receive rapid HIV-testing in dental settings. The test can be done with a simple finger prick or saliva swab and results available within 20 minutes. This could help inform people who aren't aware they're HIV-positive and reduce the spread of the virus.
Researchers have identified changes in the oral microbiome that may be associated with oral cancer development. The study found significant decreases in abundance of certain bacterial groups, such as Firmicutes and Actinobacteria, in cancer samples compared to normal tissue.
A study analyzed 21,741 tweets to understand the instant expression of migraines in social media. The findings showed that females account for 74% of migraine tweets and the US accounts for 58% of global tweets. Migraine attacks impact mood, productivity, and quality of life, with 44% reporting immediate effects.
A study published in JAMA found that restricting blood transfusions reduces healthcare-associated infections by 18%, saving lives and costs. The research suggests that a more restrictive approach to transfusions could alleviate patient suffering and reduce hospital costs.
A USC study has identified a cellular signaling pathway that converts healthy mesenchymal stem cells in the jaw into tumor cells, leading to benign but potentially harmful tumors. The researchers hope that this understanding can be used to develop target-specific treatments for these tumors.
Nanodiamonds have been found to promote bone growth and deliver proteins to treat osteonecrosis, a debilitating disease that causes bones to break down. The tiny diamonds can be administered non-invasively, potentially revolutionizing dental implant procedures.
The UCLA School of Dentistry is developing a salivary biomarker panel to detect stomach cancer using exRNA biomarkers. The research has the potential to create a new paradigm in salivary diagnostics, revealing saliva's transformative potential for detecting systemic diseases.
Research at the University of Alberta found that rats with low birth weights are more susceptible to age-related vision loss. The team's findings suggest a potential link between low birth weights and complex diseases like age-related eye disorders.
Researchers from Case Western Reserve University found that emotional intelligence (EI) is a strong predictor of clinical performance in dental school. Students with high EI scores achieved better grades and demonstrated stronger communication skills in the clinic.
A new study in Canada has found that over 40% of healthy individuals are taking daily aspirin to prevent cardiovascular disease, despite recent literature suggesting its limited benefits. The study's authors hope to raise awareness among physicians and patients about the importance of discussing anti-platelet medication use.
A one-day training program designed by U of A medical researchers led to officers being more likely to recognize mental health issues during calls and less likely to use physical force. The training resulted in long-term behaviour change and saved the police force $80,000 due to increased efficiency.
Researchers at OHSU School of Dentistry discovered a direct role of BDNF in regulating blood pressure, which may help prevent or treat high blood pressure. The study found that BDNF levels increase dramatically in nerve cells during hypertension.
A new study reveals that parents' dental fear can transmit to their children, with fathers acting as a major mediator in this process. The research analyzed 183 children and found that the father's emotional reactions significantly impact the child's perception of dentist anxiety.