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Mechanisms by which smoking worsens periodontitis discovered

Researchers identified altered gene expression in smokers with periodontitis, leading to weakened gum epithelial integrity and excessive inflammation. A new target molecule, CXCL12, was found to drive immune-cell recruitment and inflammation, making it a potential therapeutic approach.

SourceEditorial Office of West China School of Stomatology, Sichuan University·JournalInternational Journal of Oral Science·TypeExperimental study·DateJan 12, 2026

New composite hydrogel shows promise for treating dental pulp infection

A new composite hydrogel containing Li-Ca-Si bioceramics particles and gelatin methacryloyl matrix has shown promise in treating dental pulp infections by facilitating innervation and odontogenic differentiation. The hydrogel promoted Schwann cell regeneration, cytocompatibility for dental pulp stem cells, and proliferation of DPSCs.

SourceEditorial Office of West China School of Stomatology, Sichuan University·JournalInternational Journal of Oral Science·TypeExperimental study·DateDec 16, 2025

Robert I. Schattner Oral Health Center for People with Disabilities established at Hebrew University-Hadassah School of Dental Medicine

The Hebrew University-Hadassah School of Dental Medicine has established a new center dedicated to providing quality dental care for people with physical, cognitive, and complex medical conditions. The center will offer holistic, multidisciplinary care under one roof, serving approximately 30-40 patients daily.

Comparative transcriptomic analysis of human maxillary and mandibular tooth germs reveals discrepancies in gene expression patterns

The study found that upper and lower tooth germs exhibit distinct transcriptomic profiles at the cap stage, with maxillary-enriched genes associated with morphogenesis and lower-enriched genes linked to mineralization. The researchers also validated key findings using RT-qPCR and immunofluorescence staining.

SourceTsinghua University Press·JournalOral Science and Homeostatic Medicine·DateDec 11, 2025

Cutting-edge 3D AI technology transforming dental care for children

A new study reveals that a hand-held, wireless intraoral scanner paired with AI-assisted software can identify early childhood tooth decay as accurately as visual exams. The technology creates a detailed 3D model of a child's mouth within minutes, providing a comprehensive picture of their dental health.

SourceMurdoch Childrens Research Institute·JournalJMIR Public Health and Surveillance·TypeExperimental study·DateDec 8, 2025

Root canal treatment reduces heart disease and diabetes risk

A study published in Journal of Translational Medicine found that successful root canal treatment can reduce inflammation linked to heart disease and improve levels of blood sugar and cholesterol. The researchers discovered a link between monitoring blood metabolic markers after dental treatment, which could help assess recovery and risk.

SourceKing's College London·JournalJournal of Translational Medicine·DateNov 17, 2025

Tooth code cracked: Scientists find cells that know when, where, and how to grow teeth

Researchers discovered that young dental cells are directed by their position along the lingual-buccal axis to grow into distinct structures. Cells on one side formed tooth enamel, while those on the other side focused on stem cell activity and supporting tissue growth.

SourceEditorial Office of West China School of Stomatology, Sichuan University·JournalInternational Journal of Oral Science·TypeExperimental study·DateOct 23, 2025

Korea University researchers advance orthodontics with AI-assisted growth prediction

Researchers from Korea University Anam Hospital and KAIST introduce an AI system that accurately predicts a child's pubertal growth peak from a single radiograph, streamlining orthodontic treatment. The Attend-and-Refine Network (ARNet-v2) improves efficiency and accuracy, reducing radiation exposure and costs for young patients.

SourceKorea University College of Medicine·JournalMedical Image Analysis·TypeExperimental study·DateOct 16, 2025

Unveiling the therapeutic potential of abaloparatide in treating periodontal dehiscence

Researchers demonstrate that intraoral administration of abaloparatide combined with orthodontic force supports alveolar bone thickening. ABL-induced alveolar bone formation is linked to the focal adhesion pathway, where FAK activation plays a crucial role.

SourceEditorial Office of West China School of Stomatology, Sichuan University·JournalInternational Journal of Oral Science·TypeExperimental study·DateSep 19, 2025

Cracks beneath the surface: new consensus sheds light on cemental tear

Researchers developed standardized guidelines to diagnose and treat cemental tears, reducing misdiagnosis and improving patient outcomes. The consensus identifies key risk factors, diagnostic strategies, and treatment principles, empowering clinicians to recognize and manage this hidden threat more effectively.

SourceEditorial Office of West China School of Stomatology, Sichuan University·JournalInternational Journal of Oral Science·TypeLiterature review·DateSep 10, 2025

Oral health treatment in patients due for surgery is associated with significantly lower rates of postoperative pneumonia and shorter hospital stays, per observational study in one Japanese hospital, suggesting it might reduce infection risk

A single-center observational study found that planned preoperative oral care at least 2 weeks prior to surgery significantly reduced rates of postoperative pneumonia and shortened hospital stays. The results suggest that oral health treatment could be an effective strategy for reducing infection risk in surgical patients.

SourcePLOS·JournalPLOS One·DateSep 3, 2025

Teens who lose teeth to decay and injury nearly twice as likely to be bullied, study reveals

A study of over 4,400 Australian children found that those experiencing tooth loss were more than four times as likely to be bullied. Children from lower socioeconomic backgrounds and rural areas were disproportionately affected. The researchers highlight the need for improved access to dental care and prevention programs.

SourceUniversity of Sydney·JournalJDR Clinical & Translational Research·TypeData/statistical analysis·DateSep 3, 2025

Dental fear is widespread—But most people want treatment

A new study found that nearly three out of four adults suffer from dental fear, with 45.8% experiencing moderate fear and 26.8% severe fear. Most individuals interested in overcoming their fear are open to free, brief treatment options, such as virtual dental fear treatments using apps and telehealth.

SourceNew York University·JournalThe Journal of the American Dental Association·DateSep 2, 2025

Osteogenesis – Angiogenesis coupling via interlineage paracrine signaling

Researchers have discovered a specialized mesenchymal-endothelial crosstalk that supports angiogenesis and osteogenesis, enabling periodontal bone regeneration. This communication network between mesenchymal stem cells and endothelial cells drives tissue repair and regeneration, holding promise for dental therapeutic strategies and bro...

SourceEditorial Office of West China School of Stomatology, Sichuan University·JournalInternational Journal of Oral Science·TypeExperimental study·DateAug 5, 2025

New study identifies key ingredients to expanding dental care in the safety net

A new study from the University at Albany's Oral Health Workforce Research Center analyzed data on Federally Qualified Health Centers and found that capacity-building steps such as investing in skilled providers and improving infrastructure enable more people to access essential health services. The study identified three leading facto...

SourceUniversity at Albany, SUNY·JournalJournal of Public Health Dentistry·TypeData/statistical analysis·DateJul 8, 2025

JDR Clinical & Translational Research publishes supplemental issue on HSRA’s role in the academic oral health workforce

A supplemental issue of JDR Clinical & Translational Research highlights the importance of investing in long-term faculty career development supported by HRSA programs. The publication showcases innovative work done by junior dental faculty, demonstrating the need to address pressing dental shortages and expand access to care.

SourceInternational Association for Dental, Oral, and Craniofacial Research·JournalJDR Clinical & Translational Research·DateJun 20, 2025

Researchers build a better dental implant

A new dental implant wrapped in a biodegradable coating with stem cells and protein helps retain nerve tissue, enabling the implant to mimic real teeth's sensory feedback. The coating also expands to snugly fit the socket, preserving existing nerve endings.

SourceTufts University·JournalScientific Reports·TypeExperimental study·DateJun 11, 2025

Patients say “Yes..ish” to the use of AI in dentistry

A multinational study involving Aarhus University sheds light on patients' attitudes toward AI in dental diagnostics. Patients view AI as a useful diagnostic tool but express concerns over data privacy and cost implications. The overwhelming majority insists on professional human oversight, echoing the views of dental professionals.

SourceAarhus University·JournalDentomaxillofacial Radiology·TypeObservational study·DateJun 2, 2025

Global survey highlights the challenges of VR-haptic technology in dental education

A global survey of 156 institutions found that technical limitations, such as haptic precision issues, and financial constraints are significant barriers to the adoption of VR-haptic technology in dental education. The study suggests that cost-reduction innovations and targeted faculty training are needed to address these challenges.

SourceUniversity of Eastern Finland·JournalFrontiers in Dental Medicine·TypeSurvey·DateApr 25, 2025

HKU cross-disciplinary research reveals oral microbiota as promising screening tool for young children with autism spectrum disorder (ASD)

A cross-disciplinary research team from HKU has found a connection between oral microbiota and ASD, identifying 11 bacterial species as potential biomarkers. The study developed a prediction model with an 81% accuracy rate for early detection, paving the way for non-invasive screening tools during dental check-ups.

SourceThe University of Hong Kong·JournalJournal of Dentistry·TypeExperimental study·DateApr 8, 2025

Study links lack of oral health care with complications during pregnancy

A new study found that pregnant women who received preventive oral health care had a lower risk of developing gestational diabetes and hypertensive disorders. The research highlights the importance of integrating oral health education and services into maternal healthcare, particularly in underserved populations.

SourceUniversity at Albany, SUNY·JournalThe Journal of the American Dental Association·TypeData/statistical analysis·DateMar 20, 2025

Dental implants still functional after forty years

A recent study from the University of Gothenburg found that dental implants continue to function well after nearly forty years. The implants, developed by Professor Per-Ingvar Brånemark, have been shown to remain stable and integrate with bone over an extended period.

SourceUniversity of Gothenburg·JournalClinical Implant Dentistry and Related Research·TypeObservational study·DateMar 3, 2025

Fish-friendly dentistry: New method makes oral research non-lethal

Researchers at OIST have developed a customizable method for studying detailed dental characteristics of living fish and vertebrates without harming them. This approach allows for non-destructive examination of tooth replacement and development over time, revealing valuable information on feeding habits and comparative anatomy.

SourceOkinawa Institute of Science and Technology (OIST) Graduate University·JournalJournal of Morphology·TypeExperimental study·DateDec 26, 2024

VR-haptics-enhanced training holds potential to transform dental education

A new literature review highlights the transformative potential of VR-haptics in dental education, offering innovative training opportunities to complement traditional practices. The review found that VR-haptic simulation has demonstrated significant value as a complementary tool in dental simulation practice.

SourceUniversity of Eastern Finland·JournalJournal of Dental Education·TypeLiterature review·DateDec 18, 2024