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A potential antiviral for SARS and SARS-like coronaviruses

A UC Riverside-led study has identified a potential antiviral therapy for SARS and SARS-like coronaviruses by targeting the papain-like protease enzyme. The research reveals that subgroup 2b PLpros selectively target specific host immune pathways, making them a promising target for future coronavirus therapeutics.

The body fights infection amidst 'waves' of regulatory CD4+ T cells

A new study from the La Jolla Institute for Immunology reveals that two groups of regulatory CD4+ T cells develop at different times to combat acute inflammation. The early Tregs reduce autoimmune damage, while the second wave shuts down the entire immune response to signal infection clearance.

Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

New detailed immune-profiling method uses only DNA from blood

A novel immune-profiling method can return detailed immune cell type proportions using only DNA from blood, potentially allowing for individualized prediction of outcomes in immunotherapy patients. This approach offers the opportunity to ask and answer questions about the immune system in health and disease.

CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

Initial COVID-19 infection on the single-cell level, revealed

Scientists sequenced the gene expression profiles of more than 170,000 individual cells to shed light on a key mystery: the role of Type I Interferons (IFN) during viral infections. The study reveals interferon plays a crucial role in clearing the virus by alerting immune cells, such as macrophages, to search and destroy infected cells.

Meat, MS and the microbiome

A study by UConn Health and Washington University School of Medicine found that eating more meat correlates with worse MS symptoms, altered gut bacteria, and increased immune cells. The research identified key bacteria and metabolites associated with the disease, providing new insights into its causes.

Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

Scientists discover new avian immunological pathway

Researchers at UC Riverside have identified a new host protein interaction in chickens that triggers a strong immune response against viral infections. The discovery sheds light on the differences between bird and human immune responses to zoonotic viruses.

New study suggests two paths toward ‘super immunity’ to COVID-19

A new study finds that breakthrough infections following vaccination and natural infection followed by vaccination provide roughly equal levels of enhanced immune protection. Researchers at OHSU found that both groups generated greater levels of immunity compared to those who were vaccinated with no infection.

Make-up of gut microbiome may be linked to long COVID risk

Researchers found a distinct microbial profile associated with long COVID symptoms, including fatigue, muscle weakness, and insomnia. Patients with long COVID had a less diverse and abundant gut microbiome compared to those without the condition.

Pre-existing immune cells can predict early response to hepatitis B vaccine

Immunosequencing of T cells combined with machine learning techniques reveals that participants with higher numbers of pre-existing memory CD4 T cells develop immunity more quickly and produce more antibodies following vaccination. This study has significant implications for immunity and vaccine development efforts.

SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Breakthrough COVID-19 infections spur strong antibody responses

A recent study found that individuals vaccinated three times or those who were vaccinated after an earlier COVID-19 infection had comparable neutralizing antibody activity to those with a breakthrough case. The study suggests that repeated exposure to SARS-CoV-2 antigens enhances the quality of antibody responses.

Bid to discover how immune systems recognise fungal invaders

The four-year programme will investigate the chemical signatures that trigger immunity in fungal infections, which kill an estimated 1.6 million people worldwide annually. By understanding these signatures and how fungi disguise them, researchers hope to uncover the origins of antifungal immunity.

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

Additional antibodies may protect against COVID

Researchers at Lund University discovered that non-neutralising antibodies can also protect against Covid-19 by facilitating phagocytosis. The findings suggest that broader protection from antibodies may be more effective in combating mutations of the virus.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Hostile takeover in the cell

Researchers discovered that pathogens can hijack mitochondrial defense mechanisms by mimicking host proteins, effectively disarming the mitochondria. This allows the pathogen to acquire essential nutrients and evade the host's immune response.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

COVID-19 can trigger self-attacking antibodies

Researchers found that people infected with COVID-19 develop a wide variety of autoantibodies up to six months after recovery, and these autoantibodies persist over time. The study suggests that understanding these autoantibody responses could help identify ways to treat and prevent long-term symptoms.

What makes an mRNA vaccine so effective against severe COVID-19?

A new study reveals that mRNA vaccines activate a type of helper cell called T follicular helper cells, which assist in creating powerful antibodies and drive the development of immune memory. This strong response helps prevent severe disease and death, even against highly mutated variants like omicron.

Garmin GPSMAP 67i with inReach

Garmin GPSMAP 67i with inReach provides rugged GNSS navigation, satellite messaging, and SOS for backcountry geology and climate field teams.

Immune memory less durable after severe COVID-19, study suggests

A new study found that infection-fighting B cells retain better memory of the coronavirus spike protein in patients who recover from less-severe cases of COVID-19 than those recovering from severe cases. This hints at subtle differences in the quality of immune response based on COVID-19 severity.

Mechanism for DNA invasion of adenoviral Covid-19 vaccines discovered

A new study reveals the sophisticated mechanism by which adenoviruses infect human cells and transfer foreign DNA into their nucleus. Protein V plays a crucial role in increasing the virus particle's stability and preventing premature DNA release, which triggers an anti-viral alarm system.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Once upon a BCG vaccine

Researchers at La Jolla Institute for Immunology identified Th1* cells as a key marker in the body's immune signature following BCG vaccination. The study found that these cells respond well to the vaccine and can help fight the Mycobacterium tuberculosis bacterium that causes TB.

Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Infant immune systems are stronger than you think

A new study reveals that infant immune systems are robust and efficient, allowing them to quickly respond to new pathogens. This may explain why infants are less affected by COVID-19 than adults, who take longer to react.

A longer-lasting COVID vaccine? UCLA study points the way

Researchers at UCLA have identified rare T cells capable of targeting a protein found in SARS-CoV-2 and other coronaviruses. By adding a fragment of this protein to vaccines, they hope to create a longer-lasting immune response and increase protection against new variants. This breakthrough could lead to more effective COVID-19 vaccines.

How the body uses fat to fight infection

Researchers discovered that blood stem cells use high-energy fatty acids from the body's fat stores to power up their response to infection. This finding could lead to new approaches in treating bacterial infections, particularly in vulnerable and older individuals.

Revealed: How SARS-CoV-2 evades our immune system

Researchers at Hokkaido University and Texas A¼M University identified a key mechanism used by SARS-CoV-2 to evade host immune systems, targeting the MHC class I pathway. The study found that the virus suppresses the activation of this pathway using the ORF6 protein, allowing it to persist in the body and infect others.

Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Study reveals how bacterial pathogen adapts to nutritional stress

Researchers at Illinois provided insight into the signal transduction mechanism utilized by Staphylococcus aureus's TCS ArlRS in response to host-imposed manganese and glucose starvation. The study found that histidine kinase ArlS is necessary for activation of response regulator ArlR under both manganese and glucose-limited conditions.

New vaccine ingredient shows promise

A new particulate saponin/TLR agonist vaccine adjuvant has been shown to alter lymph flow and modulate adaptive immunity. This study demonstrates the potential of this ingredient as a more effective vaccine booster.

Davis Instruments Vantage Pro2 Weather Station

Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

New review highlights cancer-crushing viruses

A recent review article describes a class of viruses known as oncolytic viruses, which have the remarkable ability to target and destroy cancer cells. Researchers are exploring these viruses for cancer therapy, with some showing promising results in stimulating an immune response against cancer.

Sky-Watcher EQ6-R Pro Equatorial Mount

Sky-Watcher EQ6-R Pro Equatorial Mount provides precise tracking capacity for deep-sky imaging rigs during long astrophotography sessions.

Exposure to harmless coronaviruses boosts SARS-CoV-2 immunity

Previous antibody responses to harmless coronaviruses contribute to SARS-CoV-2 immunity, reducing infection severity and hospitalization rates. Researchers found that people with strong immune responses to other human coronaviruses have some protection against SARS-CoV-2 infection.

Age, sex and waning COVID-19 antibodies

A study found that individuals under 65 had higher antibody levels than those over 65, with women outperforming men. However, by six months post-vaccination, antibody levels dropped significantly for everyone in the study group.

Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.