Articles tagged with Neurology
A new treatment combining restricted arm use with intensive physical therapy improved function and skills on the weak side in infants with perinatal arterial ischemic stroke. While results were promising, differences in responses among children highlight the need for further research.
A new AI-powered model can read a brain MRI and diagnose neurological conditions with up to 97.5% accuracy, predicting treatment urgency and automating alerts for immediate medical attention. The technology has the potential to transform neuroimaging at health systems across the US, reducing workload and improving patient outcomes.
Researchers have found that adding daily asundexian to antiplatelet therapy can reduce the risk of a second ischemic stroke without increasing bleeding risks. The study, which included over 12,300 stroke survivors, suggests that asundexian could be widely used for patients who have had non-cardioembolic strokes or TIA.
A new study highlights the clinical relevance of brain functional connectome uniqueness in identifying biomarkers for major depressive disorder. Researchers found that patients with MDD displayed reduced FC uniqueness, especially in frontoparietal and sensorimotor networks.
Researchers have developed a long, needle-thin brain electrode with channels that enables neural signal recording and precisely targeted medication delivery across different brain regions. The technology has primarily been developed for basic research but may be important for future treatments in epilepsy and other neurological diseases.
Researchers found that certain types of CD8+ killer T cells are more abundant in people with MS and target the EBV virus, indicating the virus may trigger an immune response leading to progressive neurological damage. The study suggests that interfering with EBV could have a significant impact on other autoimmune diseases.
A rare case of hyperammonemic encephalopathy caused by 5-fluorouracil (5-FU) chemotherapy has been reported, highlighting the importance of monitoring neurological symptoms in patients receiving 5-FU. The patient's symptoms resolved after stopping 5-FU and administering lactulose and intravenous fluids.
A new study has found that improving blood flow to the brain by opening narrowed carotid arteries does not improve cognitive skills. The CREST-2 trial compared treatments and found no difference in thinking or memory over time among participants who received stenting, surgery, or intensive medical therapy.
A new study identifies the somato-cognitive action network (SCAN) as responsible for Parkinson's disease symptoms, which can be treated with non-invasive transcranial magnetic stimulation. Targeting this network improves symptoms more than twice as much as treatments targeting nearby brain areas.
Researchers found that adding alteplase to thrombectomy can significantly increase the chances of an excellent recovery in patients with large-artery ischemic strokes. The CHOICE2 trial showed improved outcomes in patients who received clot-busting medication after successful thrombectomy.
A recent study published in Neurology Open Access found that following a Mediterranean diet is associated with a reduced risk of stroke among women. The study, which involved over 105,000 participants, showed that the diet was linked to lower rates of ischemic and hemorrhagic strokes, as well as overall stroke risk.
Researchers found a synthetic protein, recombinant factor VIIa, can reduce bleeding in patients with a 'spot sign' on CT brain imaging who are treated within 90 minutes of stroke onset. These patients also experienced better outcomes and reduced ICH growth.
A blind patient partially recovered natural vision through electrical stimulation of the visual cortex, independent of the implant. The recovery was sustained over time and remained even after the device was removed, suggesting individual factors may have contributed to this outcome.
The American Heart Association has awarded 11 exceptional scientists in stroke and brain health, including Bruce Ovbiagele, Pooja Khatri, and Raghu Vemuganti, for their groundbreaking research findings and contributions to the field. The recipients will be recognized at the International Stroke Conference 2026.
A new study by McGill University researchers offers a potential solution for infant hydrocephalus, a life-threatening condition that affects 1 in 1,000 newborns. RNA therapy has been shown to prevent the condition in mice models, with a promising impact on treating genetically caused hydrocephalus.
A new risk calculator estimates the likelihood of adults developing dementia within ten years after a stroke. Researchers created a tool that stratifies people into five different levels of dementia risk based on underlying health and stroke characteristics.
A preliminary study found that stroke survivors who felt less able to openly share their feelings had slower physical and cognitive recovery. Researchers assessed participants' perception of social constraints at 3 months after their stroke, revealing a link between social constraint and overall disability.
Researchers examined post-stroke symptoms and found patients with walking difficulties are more likely to be disabled, while those with numbness are less likely. The study also identified 'silent' swallowing problems after stroke, where survivors may not report any symptoms but still have real difficulty protecting their airway.
A study found that women who have had an ischemic stroke are at a higher risk of having another stroke during pregnancy and in the six weeks after childbirth. This increased risk is not influenced by other risk factors, emphasizing the need for targeted preventive efforts.
A preliminary study found that monitoring driving behavior may help identify older adults at higher risk for unsafe driving, loss of independence, and subtle cognitive problems. People taking ACE inhibitors tend to maintain safer driving habits even with brain scans showing damage.
A new smartwatch app called SocialBit measures social interactions of hospitalized stroke survivors, potentially preserving cognition, social engagement, and quality of life. The app distinguishes between hospital personnel and non-hospital interactions, identifying potential cases of social isolation.
A type of electromagnetic therapy combined with physical therapy significantly reduced overall disability in stroke survivors. Researchers found that this therapy stimulated specific brain pathways and improved functional recovery for patients after stroke.
A preliminary study suggests that people with a type of aneurysm and cervical artery dissection do not have an increased risk of stroke within the first six months after diagnosis. This finding provides important information to help healthcare professionals better monitor and manage patients during this critical period.
A study analyzing hospital registry data found that people taking multiple antiplatelet medications after a brain bleed were more likely to die before leaving the hospital. The researchers compared patients with no antiplatelet therapy to those taking one or two antiplatelet medications, finding a higher risk of death in the latter group.
A study found that cerebral amyloid angiopathy (CAA) significantly increases the risk of developing dementia within 5 years, even more than stroke. Researchers analyzed Medicare data from over 1.9 million adults and found that CAA greatly increased dementia risk, regardless of whether patients had a stroke or not.
A large international study found that patients with long COVID-19 in the US report higher rates of brain fog, depression, and cognitive symptoms compared to those in India and Nigeria. The study suggests that lower stigma and greater access to neurological and mental health care may contribute to these differences.
A new study reveals how Parkinson's spreads from the gut to the brain via immune cells, identifying a key role for gut macrophages in transporting toxic proteins. Reducing these cells can slow disease progression and improve motor symptoms in mice.
Researchers used MRI analysis to measure glymphatic system activity, finding changes related to IIH stage and pressure levels. The findings suggest a noninvasive test could diagnose IIH more reliably, improving treatment options for patients with symptoms including headaches and vision loss.
Virginia Tech researchers identified a malformed area in the corpus callosum and pattern of bad connections that may help doctors diagnose Leigh syndrome earlier. The study found that developmental defects can be seen before symptoms appear, suggesting potential for earlier intervention.
Cancer cells tap into the nervous system's power grid by forming synaptic contacts with nerve cells, promoting tumor growth and spread. Venkataramani's research aims to repurpose the drug perampanel for glioblastoma treatment and develop gene therapy approaches to disconnect tumors from the nervous system.
A new study discovered two previously unidentified fat distribution types associated with extensive gray matter atrophy and accelerated brain aging in men and women. Individuals with 'pancreatic-predominant' and 'skinny fat' profiles showed increased risk of neurological diseases, cognitive decline, and brain health issues.
A quarter of pregnant patients suffering stroke symptoms were misdiagnosed due to overlooked warning signs, according to a new study. The researchers highlight the need for better clinician education and decision-support tools to improve maternal health outcomes.
A 82-year-old woman was treated with hyperbaric oxygen therapy for severe carbon monoxide poisoning after conventional oxygen therapy failed to produce significant improvement. The patient demonstrated considerable neurological recovery and full communication abilities after a single session of HBOT.
A study finds that nearly half of newborns with severe spina bifida experience breathing problems during sleep, which can be detected through comprehensive sleep studies. Early treatment may significantly improve cognitive development in these high-risk infants.
The American Heart Association is hosting multiple pre-conference symposia at the International Stroke Conference in New Orleans, February 4-6, 2026. These symposia cover topics such as state-of-the-science stroke nursing, brain health, and addressing disparities in stroke care. The events are designed to advance stroke and brain healt...
A recent study published in The Lancet Neurology found that patients with acute ischemic stroke who experience prolonged transfer times are more likely to leave the hospital with significant disability. The study of over 20,000 patients highlighted the need for shorter transfer times to improve patient outcomes.
A study published by the American Academy of Neurology found that women who experienced an ischemic stroke during pregnancy or postpartum were at a higher risk of cardiovascular events and depression. The study also showed lower employment rates among these women compared to those without a stroke.
The number of heart disease and stroke deaths in the US has declined, but these conditions still account for over a quarter of all deaths. The latest data from the American Heart Association shows that fewer people are dying from any cause, with death rates improving, but cardiovascular disease remains a major concern.
A case-control study found that even low-level air pollution in Sweden may increase the risk of developing motor neuron disease. Long-term exposure was also associated with poorer disease prognosis after diagnosis.
A Swedish study published in JAMA Neurology found that prolonged air pollution exposure is associated with a higher risk of developing motor neuron disease, including ALS. Long-term exposure to even low levels of air pollutants was linked to faster disease progression and increased mortality rates.
The study reveals cerebrovascular disease as the third leading cause of death among adults in China, with a higher risk among men and those residing in northern regions. Dementia and Parkinson's disease also show high prevalence rates, while unique demographic patterns are observed for other neurological disorders.
Adults with asthma who experience depressive symptoms have elevated blood levels of brain-derived neurotrophic factor (BDNF), a protein typically reduced in major depressive disorder. Physical activity may also play a role in depression management, as lower activity levels are linked to worse moods.
A new blood biomarker, brain-derived tau (BD-tau), tracks the extent of brain injury after ischemic stroke over time. It also predicts patient outcomes months to years later and detects differences associated with successful vessel reopening. BD-tau has potential applications for other neurological conditions.
JMIR Publications' JMIR Neurotechnology journal now accepts submissions on novel technological advances for neurological disorders. Researchers can submit review articles exploring emerging technologies, such as neurofeedback, neurosurgery, and brain-machine interfaces.
A new UCLA study finds that the Patient Safety Indicator 04 (PSI 04) metric is fundamentally flawed when applied to emergency stroke care. The researchers argue that the metric incorrectly flags unavoidable complications of severe strokes, rather than problems with the procedure itself.
A new approach to assessing patients with disorders of consciousness combines six assessment techniques, including high-density EEG and functional MRI. The study reveals that combining data from multiple techniques significantly improves model performance and provides a synthetic and precise assessment of patient outcomes.
New research reveals that the immune system has a potent weapon against the brain parasite Toxoplasma gondii: an enzyme called caspase-8. This discovery offers new insights into how our bodies control the parasite and may lead to better treatments for patients with compromised immune systems.
A Northwestern University study found an injectable regenerative nanomaterial helps protect the brain during a vulnerable window after most common type of stroke. The therapy successfully crossed the blood-brain barrier and reduced brain damage, showing no signs of side effects.
Researchers at the University of Illinois discovered that propofol, a common anesthetic agent, can improve cognitive function after surgery in older individuals. Additionally, intranasal insulin was found to mitigate age-related memory impairment by modulating neuroinflammatory mechanisms.
A study published in the Journal of Proteome Research found that acute systemic inflammation causes region-specific metabolic disruption in the cerebrum, impairing neuronal metabolism. Key findings include reduced NAA levels and elevated urea accumulation, suggesting a link between inflammation and neurodegenerative disorders.
A new study published in Neurology found an association between high-fat dairy products and a reduced risk of dementia. Researchers analyzed data from 27,670 people in Sweden and found that those who ate more high-fat cheese had a 13% lower risk of developing dementia.
Trigeminal neuralgia is a debilitating condition causing sudden, severe electric shock-like pain in the face. University Hospitals has successfully treated two initial patients with the OneRF Trigeminal Nerve Ablation System, providing complete pain relief without complications. The minimally-invasive procedure uses radiofrequency ener...
A recent study found that female participants experienced slightly worse recovery from ischemic stroke compared to male participants. The study analyzed data from 1,046 people who experienced their first stroke and tracked their recovery over three, six, and 12 months. Female participants showed poorer recovery in daily tasks such as e...
Researchers investigated a combination of stem cell therapy and BDNF enhancement to treat Parkinson's disease. The strategy aims to promote neuroregeneration and functional recovery by introducing progenitor cells genetically matched to the donors, while upregulating BDNF to mitigate neuronal loss and enhance motor function.
A study highlights how social media is transforming neurosurgical education, collaboration, and case consultations globally. Platforms like Neurosurgery Cocktail have democratized neurosurgical knowledge, supporting high-level discourse among experts.
The American Academy of Neurology has issued a new guideline for the management of functional seizures, which are episodes that can look or feel like epilepsy or fainting. The guideline recommends psychological interventions such as cognitive behavioral therapy to increase the likelihood of achieving freedom from functional seizures.
NEJM Clinician curates highly relevant clinical insights from over 150 peer-reviewed journals to give physicians clear guidance without the noise. The weekly publication delivers summaries and commentary in a concise, 30-minute read, helping healthcare providers stay informed and confident in their decisions.
A new study found that maternal psychological distress experienced at 1 year postpartum has a stronger association with neurodevelopmental delay in toddlers compared to prenatal distress. The researchers also discovered that experiencing distress during both pregnancy and postpartum periods further amplifies the risk of delays.
Researchers developed a new tool, Fear Avoidance after Concussion Tool (FACT), to assess fear avoidance behavior following a concussion. The 28-item questionnaire can be completed in five minutes, enabling targeted management for individuals at risk of persisting post-concussion symptoms.
The EBRAINS Summit 2025 will bring together experts to assess how neuroscience can drive medical progress, digital innovation, and responsible data use. Preliminary results from the EPINOV clinical trial, integrating virtual brain technology for epilepsy surgery planning, will be presented.