Articles tagged with Neurosurgery
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A NIH panel emphasizes the importance of removing stigma associated with fecal and urinary incontinence, recommending increased public awareness and provider education. The panel also highlights the need for research studies to fill knowledge gaps and develop effective prevention and treatment strategies.
A study by researchers at University Hospitals of Cleveland and Johns Hopkins University found that intraoperative MRI can help detect residual disease and modify surgical plans, leading to additional resections in 73% of cases. The added imaging time was approximately 35 minutes per case.
A study found that the brains of term infants with congenital heart disease are more similar to those of premature newborns than normal term infants, indicating impaired brain development before birth. The research suggests abnormal fetal circulation and lower oxygen levels may contribute to these impairments.
A new study found that 18% of bariatric surgery candidates were not psychologically cleared for surgery, citing frequent overeating as a coping mechanism for stress and uncontrolled psychiatric disorders. Researchers emphasize the importance of pre-operative screening to determine suitable surgical candidates.
A coalition of physicians from various medical specialties urges the expansion of catheter-based treatments for stroke, citing a shortage of trained physicians and limited use of clot-busting drugs. They propose adapting neuro-rescue skills to increase the number of available physicians for 24/7 treatment.
Research found 90% of patients with multiple aura types had seizures originating from the non-dominant side of their brain. Epilepsy surgery was effective in stopping seizures in over half of study participants.
The University of Cincinnati has received a $1.7 million grant from the National Institutes of Health to research molecular treatment of brain injury. Dr. Kenneth Strauss will study eicosanoids, which can protect healthy brain cells from further damage.
A new gene therapy clinical trial has reported promising results in improving motor function for patients with Parkinson's disease. The study found significant improvements in both the off-state and on-medication phases, with some patients showing impressive gains of up to 65 percent.
A study published in The Lancet found that gene therapy can safely alleviate symptoms of Parkinson's disease, with significant improvements seen in movement and motor scores. The treatment involves injecting genetic information directly into brain cells, eliminating the need for indwelling hardware associated with deep-brain stimulation.
A new 3D ultrasound scanner developed by Duke University researchers enables better brain tumor detection and minimally invasive surgery guidance. The device, inserted through a small hole in the skull, produces high-quality images of brain structures, overcoming limitations of traditional MRI and CT scans.
A new pacemaker-like device has been developed to treat treatment-resistant depression, showing statistically significant improvements in mood and cognitive abilities. The research, led by James McInerney and Elana Farace, offers hope for millions of people affected by the debilitating disease.
Patients who experience a significant drop in blood pressure during bypass surgery may be at risk for early difficulties in thinking, learning, and memory. Those with higher pre-surgery blood pressure levels were more likely to have decreased cognitive scores after the procedure.
Researchers have developed a dual-imaging technique that combines functional magnetic resonance imaging (MRI) and diffusion tensor tractography to outline important areas of brain function and their connections prior to surgery. This approach has been used in 20 cases at Cincinnati's University Hospital and shows promising results in o...
A miniature robot developed by Prof. Leo Joskowicz and his team enables precise targeting in neurosurgical procedures, reducing complications and improving patient outcomes. The system, which uses preoperative scans and real-time image guidance, has been recognized with a Kaye Innovation Award.
A study published at the University of Pittsburgh Medical Center found that endoscopic brain surgery is effective in removing life-threatening tumors in children, with minimal complications and no neurological damage. The minimally invasive approach allows for faster recovery times and a shorter hospital stay.
A recent study published in Neurology found that patients undergoing combined heart bypass surgery and carotid endarterectomy experience a 38% higher chance of death or postoperative stroke compared to those who undergo coronary artery bypass surgery alone. The study suggests that the combined procedure may not provide additional benef...
A new study found a significant drop in patients undergoing carotid endarterectomy for inappropriate reasons. The study, published in Neurology, credits the decline to randomized controlled trials that clarified the surgery's proper use.
Mayo Clinic researchers use advanced MRI to predict surgical success in rare sciatic notch dumbbell-shaped tumors. The 3-Tesla MRI system provides detailed images of tumor and nerve relationships, allowing for safe removal of tumors while protecting nerves.
Researchers found that slow theta oscillations tune into high-gamma waves, allowing areas of the brain to coordinate activity and transmit information. This coupling enables top-down executive processes like attention and memory to be connected to low-level perceptions and actions.
The Pauletta and Denzel Washington Family Gifted Scholars Program in Neuroscience awards $2,500 monthly support to graduate researchers and $2,000 per month to undergraduate students. The program aims to train the next generation of life scientists and promote significant contributions in the sciences.
A novel approach to epilepsy surgery in young children with tuberous sclerosis has shown promising results, with 17 of 25 patients freed from seizures after a multi-stage brain operation. The procedure involves multiple surgeries to remove seizure-causing tissue, and may improve developmental outcomes for affected children.
Researchers have developed a new method for detecting brain tumours during surgery using a fluorescent compound, which significantly improves complete tumour removal rates (65% vs 36%) and survival rates without tumour progression (41% vs 21%). The technique has been shown to be safe with no significant difference in serious side effects.
A study by Mayo Clinic researchers found that epilepsy surgery is durable and effective, improving quality of life for patients with intractable epilepsy. The procedure removed the focal region of brain disease in 399 consecutive patients, with a 4% risk of complications.
A study published in Neurology found that over 70% of people with Chiari Malformations experience sleep apnea and daytime sleepiness. Surgery to relieve compression on the brain stem improved symptoms, reducing central sleep apnea occurrences by 90% and micro-arousals by 30%.
A team of researchers from the University of Illinois at Urbana-Champaign has developed an alternative therapy to surgery for brain cancers. By engineering T-cell receptors with enhanced binding capacity, the approach aims to eradicate tumors with minimal side effects.
Researchers have found that a marker for serotonin systems can identify epilepsy-generating brain areas, even in patients with normal MRI scans. This breakthrough has the potential to reduce the need for invasive EEG studies and improve surgical outcomes for patients with uncontrolled seizures.
Dr. Anthony Marmarou's international team developed consensus guidelines for diagnosing and treating idiopathic normal pressure hydrocephaly (NPH). The new guidelines recommend a combination of diagnostic tests to predict patient responsiveness to shunt surgery, improving treatment outcomes.
A new non-surgical approach combining stent-assisted coil embolization has shown success in treating wide-necked brain aneurysms, improving patient outcomes with minimal recovery time. The procedure has been found to have a high rate of complete closure without compromising the parent vessel.
A Phase IIa study found that patients given clazosentan suffered from significantly fewer and less severe cases of cerebral vasospasm compared to placebo. The treatment was also associated with a lower incidence of new cerebral infarcts.
A study found that 50% of patients who underwent temporal lobectomy for epilepsy were seizure-free after 30 years. Patients who experienced seizures within the first year after surgery had a lower likelihood of being seizure-free in the long term.
The OHSU study found that ThinkFirst significantly improves knowledge of injury prevention among program participants, leading to a decline in traffic-related fatalities and injuries. The program has educated over 250,000 children on injury prevention since its inception in Oregon.
A study found that combining carotid endarterectomy (CEA) and coronary artery bypass graft (CABG) surgeries increases the risk of post-operative stroke by 6.8%, compared to 1.8% in CABG alone. Experts believe further randomized trials are necessary to assess the appropriateness of this combined procedure.
Researchers developed a classification system to treat thrombotic aneurysms, finding that one-third can be treated surgically with conventional clipping. The study also discovered that bypass and occlusion procedures yield more favorable results for unclippable aneurysms.
A study of 387 patients with epilepsy found that the timing of post-surgery seizures is a key predictor of long-term success. Patients who experienced seizures within four months of surgery had a worse prognosis, while those who waited longer tended to become seizure-free.
Dr. Brenda Milner, a renowned cognitive neuroscientist, has been awarded the 2005 Gairdner Award for her pioneering work on brain function and memory systems. Her research with patient HM has significantly advanced our understanding of episodic and procedural memory.
A study published in the Journal of Neurosurgery found that golf-related head injuries in children increased by 15% between 1996 and 2002. The majority of these injuries occurred outside golf courses, highlighting the need for cautionary guidelines and safety training programs to prevent accidents.
A new JAMA study found that brain tumor treatment varies greatly among patients, with inconsistent use of chemotherapy and anti-convulsant medication. The study also highlights the need for improved communication between healthcare providers and patients, as well as increased participation in clinical trials.
A large study found that early surgery does not reduce deaths and disability in patients with brain hemorrhage. Only patients with small blood clots near the surface of the brain may benefit from surgical intervention.
A study of 325 patients who underwent temporal lobe removal found that early seizures after surgery were eight times more likely to lead to persistent epilepsy. This suggests that some individuals may have epilepsy that is more persistent and resistant to treatment.
A new device study shows spinal cord injury patients experiencing some degree of functional recovery after six months, with improved sensation and motor function recorded at one year. The oscillating field stimulator device has been shown to promote nerve fiber regeneration, offering a potential treatment option for severe injuries.
A new minimally invasive procedure using angioplasty and stenting is shown to be as effective as surgery in preventing strokes. The treatment involves widening the carotid artery to improve blood flow, with comparable rates of complications and a low rate of re-narrowing.
Researchers tested electrical stimulation's influence on stroke recovery, showing participants experienced meaningful motor recovery gains. The study aims to validate these findings and potentially reverse paralysis, restoring patients' function and normal lifestyle.
Researchers discovered that patients with medically intractable epilepsy may develop new adult brain cells post-operatively. This cell generation could be the cause of recurring seizures and provide a potential target for future treatment and prevention strategies.
Researchers found that mice with brain tumors treated with stem cells showed increased blood supply and decreased tumor growth, living on average 50 percent longer than untreated mice. The Congress of Neurological Surgeons Annual Meeting presented this promising research.
Weight-reduction surgery patients are at risk of developing peripheral neuropathy, a condition causing pain, numbness, and weakness. Following nutritional guidelines and attending post-surgical care programs can help prevent nerve damage.
A recent study published in Epilepsia found that selective amygdalohippocampectomy (SAH) surgery can lead to verbal memory loss in patients, especially those who underwent left temporal lobe surgery. The study revealed that 30% to 50% of patients who underwent SAH on the left side showed no recovery of verbal memory after 12 months.
According to the study, the nasal endoscopic approach was successful in treating cerebrospinal fluid rhinorrhea, with 92% of patients experiencing long-term success. The procedure involves using small cameras and monitors to operate with minimal trauma, reducing the risk of complications.
Researchers at Rush University Medical Center are exploring a new gene transfer technique that uses CERE-110 to deliver nerve growth factor to specific areas of the brain affected by Alzheimer's disease. The goal is to prevent cell death and reverse cell atrophy, which may have a widespread effect on the entire brain.
A new Mayo Clinic study finds that CABG surgery is not a risk factor for dementia, but patients may experience cognitive decline due to surgical complications. The study took an innovative approach by starting with dementia cases and comparing them to non-demented control groups.
A recent study published in The Lancet found that Bispectral Index (BIS) monitoring can significantly reduce the incidence of awareness during surgery. By using BIS-guided anaesthesia, patients at risk experienced only two cases of awareness compared to 11 reported cases with standard care.
Researchers studying epilepsy patients who underwent brain surgery on either side found that those with left-brain surgery experienced decreased immune function, while right-brain surgery boosted immune response. The findings raise concerns about protecting patients from infection following strokes or left-brain surgery.
Researchers found that surgery to remove fatty deposits from narrowed vessels can significantly reduce stroke risk, with a 50% reduction in strokes among those who underwent the procedure. The study's results confirm previous findings and highlight the need for more adults to be screened for narrowed carotid arteries.
A Phase I study conducted at UCSD showed promising early indications of reduced disease advancement in patients with early-stage Alzheimer's disease. The subjects who successfully completed the surgery showed a 50% reduction in their annual rate of decline on one of the measured cognitive scales.
Duke researchers found that slower rewarming reduces brain temperature and hyperthermia risks after coronary artery bypass surgery. This leads to improved cognitive outcomes for patients six weeks post-surgery. A seven-year analysis of 6,334 patients showed significant reductions in hyperthermic episodes.
Researchers at Duke University Medical Center have demonstrated the feasibility of brain-machine interfaces (BMIs) in humans, using arrays of electrodes to record brain signals and control external devices. The study showed that patients with Parkinson's disease and tremor disorders could use BMIs to play a hand-controlled video game.
A new procedure, carotid artery angioplasty with stenting (CAS) with distal embolic protection (DEP), has shown zero neurological complications in a study involving 21 patients. The minimally invasive technique adapts techniques used to open heart vessels for brain arteries, significantly reducing risk of stroke and death compared to t...
Researchers at Washington University developed a non-invasive fMRI technique to better evaluate brain surgery risks and guide operations to avoid sensitive language areas. This breakthrough holds promise for safer surgeries for nearly 200,000 Americans diagnosed with brain tumors annually.
A recent study published in Neurology confirms that 86% of children who underwent hemispherectomy at Johns Hopkins Medicine are either seizure-free or have non-disabling seizures. The surgery improves quality of life and reduces medication dependence.
Fetal surgery for spina bifida has been shown to improve leg function and reduce the need for shunts in infants. The study found that 24 of the 47 surviving infants had better neurologic leg function than predicted, while only 20 required a shunt.
The STEPS study evaluates the safety and efficacy of Spheramine, a cell therapy that produces levodopa to enhance dopamine production in the brain. The study aims to provide a new method for Parkinson's patients to achieve continuous control of motor function.