Articles tagged with Risk Factors
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
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Teen energy, calmness, empathy, maturity, and intellectual curiosity may be protective against early death, while impulsivity may increase the risk. A large study found that these traits were associated with lower mortality rates over 48 years.
Researchers at University of Utah Health identified four gene changes linked to increased suicide risk in high-risk families. These findings may lead to new treatments for those who suffer from mental health issues.
A UK population-based study found nearly one in five ICU survivors die within one year after discharge. Increased hospital use before and after ICU stay is associated with a higher risk of death, along with older age, multiple medical conditions, and organizational factors indicating high system stress.
A Penn State study suggests that children's executive functions in kindergarten can predict their mathematics, reading, and science achievement, as well as classroom behavior, in second grade. Deficits in working-memory, a key component of executive functions, are strongly linked to repeated academic difficulties across elementary school.
A study of nearly all births in Vancouver found that air pollution exposure, particularly nitric oxide, was associated with an increased risk of autism spectrum disorder. The findings suggest environmental contaminants and air pollution may be potential risk factors for ASD.
A large American Cancer Society study found that social isolation is linked to a higher risk of death from all causes combined and heart disease, with increased cancer mortality in white men and women. Addressing social isolation holds promise as it could be relatively simple and influence other risk factors.
A recent study discovered a non-coding genetic variant, rs17114036, that enhances endothelial response to blood flow, reducing the risk of coronary artery disease. This variant is associated with increased expression of phospholipid phosphatase 3 (PLPP3), which promotes vascular health.
A new study published in the journal Nutrients found that diet fluctuations can lead to a rollercoaster of risk factors for cardiovascular disease and diabetes. Repeated attempts at adopting a healthy eating pattern can have benefits, with significant improvements in blood pressure and cholesterol levels seen after just a few weeks.
Researchers developed a precision-medicine platform that uses genomic data, biospecimen measurements, and other inputs to create personalized treatment plans for mild Alzheimer's disease and at-risk individuals. The study showed significant improvements in memory function scores for 80% of participants.
A study published in the Journal of the American College of Cardiology found that black patients remain at significantly higher risk for sudden cardiac death even after adjusting for income, education, smoking, and other risk factors. The researchers suggest that unknown genetic factors may be contributing to these disparities.
The FIT project aims to address high youth football injury rates in Sweden by combining biomedical and social science disciplines. The study analyzes multiple datasets to identify risk factors, including growth, training intensity, and pressure to perform.
Researchers identified 90 genetic points associated with increased risk for both cardiovascular disease and Alzheimer's, including genes involved in lipid metabolism. The study found that targeting these genes may help lower Alzheimer's risk by managing cholesterol and triglyceride levels.
Researchers found that testing coronary calcium levels is a more accurate predictor of blocked coronary arteries and need for revascularization than standard risk-assessment equations. Coronary calcium scores can identify patients at high risk and help prevent overtreatment.
The study found that 104 countries have high fertility rates, while 91 countries have low rates, posing challenges for meeting UN goals on deaths from non-communicable diseases and suicide. The global population is projected to continue growing despite declining total fertility rates.
The Global Burden of Disease study estimates that global mortality rates stagnated in 2017, and half of countries face a healthcare workforce shortage. Only 41 out of 195 countries have more than 30 physicians per 10,000 population, highlighting the need for increased healthcare workers to achieve universal healthcare.
A new study by Anglia Ruskin University finds that around one in three LGB individuals who are bullied at school will experience similar bullying in the workplace. The study also examines the impact on job satisfaction and mental health, finding a negative association between bullying and job satisfaction.
A UK Biobank study found that certain risk factors have a greater impact on women's heart attack risk than men's. High blood pressure, smoking, and diabetes increased the risk of heart attack more in women than in men.
A new study from the University of Eastern Finland found that poor aerobic fitness in children is associated with a higher risk of type 2 diabetes and cardiovascular disease. The study's findings suggest that traditional measures of aerobic fitness may overestimate its role in identifying children at increased risk.
The prevalence of female genital mutilation/cutting among girls up to 14 years old has decreased in most African regions over the past three decades. However, the practice remains pervasive in Western Asia-Iraq and Yemen.
Research by the University of Kent found that women who have a boy are at a higher risk, with complications during delivery increasing the likelihood by 174%. The study identifies male infants and birth complications as new postpartum risk factors.
Researchers found that people with high levels of chronic noise exposure had a greater than three-fold risk of cardiovascular events. Chronic noise exposure fuels blood vessel inflammation, promoting cardiac risk.
A study by V. Wendy Setiawan and colleagues found that cancer mortality rates among Latinos in the US increase with each successive generation born in the country. The highest risk was observed among third-generation U.S.-born Latinos, followed by second- and first-generation immigrants.
Researchers discovered that breastfeeding for over six months lowers the risk of non-alcoholic fatty liver disease (NAFLD) in mothers. Women who breastfed one or more children for longer periods had a lower risk compared to those who did not breastfeed or breastfed for under one month.
Researchers found four subgroups with varying degrees of pain sensitization, with the highest degree associated with persistent knee pain. Identifying these subgroups may lead to novel approaches for preventing persistent knee pain.
A new study from Université de Montréal finds that increased pain sensitivity is a key risk factor for persistent knee pain in osteoarthritis. The research identified four subgroups characterized by varying degrees of pain sensitization, with the highest degree linked to the greatest risk of developing persistent knee pain.
A plant-based diet has been shown to improve psychological wellbeing, reduce risk factors for type 2 diabetes, and slow nerve damage. Participants who followed a vegan diet lost nearly twice as much weight and had lower blood glucose levels compared to those on other diets.
A Canadian study found that truck drivers experience high rates of musculoskeletal pain and discomfort, with factors including organizational safety climate, job satisfaction, and physical fitness contributing to the issue. The study identified potential solutions, such as holistic programs addressing multiple risk factors, and encoura...
Researchers identified a cluster of five risk factors associated with unhealthy gut microbial communities, which can increase the risk of C. diff infection. The study suggests potential preventive interventions, including dietary changes and fecal transplantation from healthy donors.
The study reveals a significant shift from mortality to morbidity, with conditions like low back and neck pain and anxiety disorders causing disability. The authors highlight the need for health services to adapt to managing long-term conditions and address social determinants of ill health.
A study published in The BMJ found that a healthy lifestyle can significantly reduce the risk of stroke, regardless of genetic profile. Lifestyle factors such as not smoking and maintaining a healthy weight were associated with a lower risk of stroke.
A new study found that Black men have a higher rate of reincarceration and shorter time to reentry compared to other groups, even with lower risk scores on standardized tools. This suggests that systemic issues such as racism and implicit bias play a significant role in recidivism rates.
Researchers at Boston University School of Medicine discovered a strong link between chronic inflammation and increased risk for Alzheimer's disease in ApoE4 carriers. Sequential measurements of C-reactive protein revealed that ApoE4 linked with chronic low-grade inflammation significantly increases AD risk.
A study of US hospital statistics from 2010-14 found a rise in stroke incidence among marijuana users, with rates increasing from 1.3% to 1.5%. Young stroke survivors also face long-term risks, with nearly 3 times the risk of adverse events compared to older patients.
A Yale-led team has identified four new genetic variants that directly damage gene sequences, accounting for an additional 5% of MS disease risk. The findings contradict previous theories on the role of common genetic variants in MS, providing promising new avenues for research and study.
Researchers used genetic and survey data from over 210,000 participants to identify correlations between known and novel skin cancer risk factors. Combining multiple factors improved predictive accuracy for skin cancer risk, particularly when including a genetic risk score.
A new study forecasts that global life expectancy will increase, but nearly half of all nations may face lower life expectancies by 2040. China and several other countries are expected to see significant gains in life expectancy, while Palestine and some high-income nations are forecast to experience declines.
A two-year study of primary school children found that increasing vigorous exercise reduces the accumulation of risk factors for type 2 diabetes and cardiovascular disease. In contrast, sedentary behaviour increases risk factors. The findings support the role of physical activity in preventing chronic diseases in childhood.
A study by Kaiser Permanente researchers has found a specific place in the human genome associated with an increased risk of erectile dysfunction. Variations in the SIM1 locus were significantly associated with a 26 percent increased risk, independent of known risk factors.
A genetic tool can identify people at high risk of heart attacks early in life, potentially preventing devastating outcomes. The technology uses genomic data to calculate an individual's underlying genetic risk for coronary heart disease.
Long-term testosterone supplementation has been linked to increased blood pressure in obese rats, raising concerns about its safety in certain populations. The study suggests that hormone therapy may not be beneficial for men with heart disease risk factors, highlighting the need for more research on complex effects of testosterone.
A NIH-funded study found that a diet high in fried and processed foods is associated with an increased risk of hypertension in black Americans. Lifestyle changes, particularly changes in diet, may help reduce this disparity.
Research reveals that women with versus without prediabetes experience significantly larger adverse differences in cardiometabolic health compared to men. Women with prediabetes had higher blood pressure, worse cholesterol profiles, and increased inflammation before the onset of type 2 diabetes.
A study of 6,900 black and white adults found that a Southern diet was the top factor associated with an increased risk of hypertension. The diet, characterized by high consumption of fried foods, organ meats, and processed meats, was linked to higher blood pressure among black adults.
A new study finds that delayed pregnancy may increase cardiovascular disease risk in both women and their children, with boys at higher risk. Researchers also found sex-specific differences in health risks of the offspring, highlighting the importance of assessing cardiovascular health during pregnancy.
Researchers analyzed data from the TBI Model System National Data and Statistical Center to identify physical, cognitive, and psychosocial characteristics associated with mortality in chronic TBI survivors. Independence in mobility and community participation were found to be important factors for long-term survival in this population.
A nationwide study in Taiwan found that stroke incidence is rising, contrary to declines in Western countries. The study examined hospital records of patients with a primary diagnosis of stroke between 2001 and 2013, and found that the incidence of ischemic stroke increased by 12% over 13 years.
Researchers found a relationship between high FGF23 levels and structural compromise in the brain, particularly in the frontal lobes, which control learning and complex cognitive functions. Elevated FGF23 levels were also associated with increased disconnection in the brain, indicating problems with brain health in those areas.
A new study found that teenagers exposed to TV and film violence and high levels of household conflict are at risk of engaging in aggressive behaviors. Parental monitoring is a strong protective factor against aggression, even when combined with other risk factors.
A 16-year Danish cohort study found comparable risks of recurrence between patients with unprovoked and cancer-related venous thromboembolism. The cumulative incidence of recurrence after incident VTE was over 15% in all groups, highlighting the need for revised risk stratification approaches.
A Stanford-led study found a link between height and varicose veins, identifying 30 genes linked to the condition and suggesting that genetic markers of height may predict disease. The researchers used machine learning combined with epidemiological methods to examine genomic data on over 400,000 people.
A study published in Circulation Journal found that increased height increases the risk of developing varicose veins, as well as genes that determine height influencing the development of the condition. Researchers also discovered a strong genetic correlation between deep vein thrombosis and varicose veins.
Fibromyalgia patients who regularly visit their physicians are much less likely to attempt suicide than those who do not. Regular care engagement is key in managing the disorder and reducing risk of suicide. The study suggests connecting patients at-risk with outpatient providers can improve care and reduce suicidal risk.
Hematologic stem cell transplantation (HSCT) survivors are at risk of bone loss and osteoporosis, increasing the likelihood of fragility fractures. The IOF expert Working Group on Cancer and Bone Disease provides clinical guidance for monitoring, evaluation, and treatment of bone loss in these patients.
The FRESH program has shown that young women in South Africa are more likely to be infected with HIV due to socioeconomic factors such as gender inequality and economic dependence. The program also identified biologic factors contributing to a higher risk of HIV infection, including hormonal levels and bacterial microbiome composition.
A recent study published in Open Heart reveals that UK heart failure patients are significantly more likely to die than their Japanese counterparts, with mortality rates being nearly twice as high. The disparity persists even after accounting for differences in patient severity and risk factors.
A new AI-powered tool, HEAL, analyzes genome sequences and electronic health records to predict individual risk for developing abdominal aortic aneurysm. The tool may one day help diagnose, treat, and prevent diseases such as AAA, neurological disorders, and cardiovascular conditions.
A new study published in Frontiers finds that short chromosome tips (telomeres) are an independent risk factor for age-related functional decline. Participants with the shortest telomeres were more likely to have reduced physical function, regardless of geographical location, age, sex, or weight.
A large prospective study of over 107,000 women found no association between physical activity and the risk of early natural menopause. The study, published in Human Reproduction, analyzed data from the Nurses' Health Study II and found that exercise was not significantly linked to a lower or higher risk of menopause before age 45.
The prevalence of hypertension globally is high and continues to increase. Targeted and population-based strategies can lead to better prevention and control of hypertension.
New research highlights the risks of cardiovascular disease in even the fittest middle-aged athletes, who often don't exhibit symptoms. Regular health check-ups and moderate exercise are crucial for prevention, according to study findings published in BMJ Open.