Articles tagged with Protein Domains
Researchers discovered the protein PHF9, which disables the function of the FA pathway, a network critical for DNA repair, blood development, and fertility. This breakthrough provides new insights into Fanconi anemia, a rare genetic cancer-susceptibility syndrome affecting millions worldwide.
Researchers at Purdue University have obtained the first-ever images of a developing dengue virus, revealing a complex developmental process that could lead to the discovery of new antiviral medicines. The immature particle is covered with protein spikes that flatten out as it matures into the infectious dengue virus.
Researchers at Johns Hopkins have determined the 3D structure of the HER2 breast cancer receptor, shedding light on its interactions with the Herceptin antibody. The findings could lead to the design of more effective drugs for treating breast cancer.
The US Navy is developing new antifouling hull coatings inspired by nature, using complex nanometer-scale patterns to prevent barnacles from attaching. These coatings have shown exceptional low settlement rates in early experiments, promising a reduction in fuel costs and frequent cleaning needs for Navy ships.
Scientists at Max-Planck-Institute for Molecular Physiology develop a new concept for more efficient search of drug candidates. By employing biologically relevant natural products as starting point, the 'domain concept' aims to increase hit rate in compound libraries.