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Boosting the body’s cancer fighters

Scientists have developed a new method to systematically discover genetic boosters for CAR T cells, a type of immune therapy. By knocking out genes that weaken CAR T cell function, researchers found a surprising genetic target: RHOG, which increases therapeutic potential when knocked out with CRISPR technology.

The curious immune cells caught between worlds

Researchers at Cold Spring Harbor Laboratory have discovered that innate-like T cells mature differently in humans than in mice, with age playing a critical role in their development. This finding has significant implications for the development of immunotherapeutics, highlighting the need to consider human-specific differences when te...

Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

The gut patrol

Scientists at La Jolla Institute for Immunology discover how gut barrier cells send secret messages to patrolling T cells, keeping them alive and active. The study sheds light on conditions like inflammatory bowel disease and highlights the importance of HVEM protein in maintaining a healthy gut microbiome.