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DNA shape and rigidity regulate key players of gene expression

Researchers at the University of Texas M. D. Anderson Cancer Center discovered that inflexible DNA within nucleosomes regulates the positioning of INO80, a chromatin remodeling complex. This unique mechanism allows INO80 to position itself on the surface of nucleosomes at the right location.

The guardian of the (epi-)genome

A research team led by Ivano Amelio found that the protein p53 acts as a key to maintaining genomic stability, preventing cancer-promoting mutations. Without p53, cells become more aggressive and prone to acquire genomic instability.

Davis Instruments Vantage Pro2 Weather Station

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