Articles tagged with Genome Sequencing
The USDA has created the first genomic map of the domesticated turkey, which could help breeders develop improved commercial breeds to meet consumer demands. The nearly complete genome map was compiled in under a year and at a fraction of the cost of sequencing chicken and cow genomes.
The international consortium has completed the majority of the genome sequence of the domesticated turkey, with over 90% of the genome sequenced and assembled. The research will provide knowledge of specific genes important in meat yield and quality, health, disease resistance, fertility, and reproduction.
The international consortium's completion of the turkey genome sequence promises to provide new insights into avian genetics and improve turkey quality. The sequence will enable scientists to better understand specific genes important in meat yield, health, and disease resistance.
Scientists at Max Planck Institute successfully analyze all genes in human genome simultaneously to identify mutation causing Mabry Syndrome. The new process reveals a mutation in PIGV gene leading to mental retardation and other symptoms.
The domestic apple genome sequence has been published, providing valuable information for breeding apples with desirable traits such as disease resistance and flavor. The study confirms that the wild ancestor of the modern domesticated apple is Malus sieversii from southern Kazakhstan.
Researchers sequenced the genomes of Jerdon's jumping ant and Florida carpenter ant, revealing clues to their complex social behavior and potential links to human aging. The findings highlight the importance of epigenetics in controlling gene expression, which may influence longevity and behavior.
Researchers sequenced the sponge genome to connect the dots between Amphimedon and other animals, revealing a striking conservation of gene structure and genome organization. The study aims to understand how patterns that have been around for a billion years have evolved or persisted.
Researchers have found that the wild populations giving rise to melons and cucumbers originated in Asia, contrary to previous assumptions. The study analyzed genetic material from over 100 species of Cucumis, revealing a close living relative of the cultivated melon is native to Australia.
The complete genome of the split gill mushroom has been published, revealing a unique enzyme-based digestive apparatus that enables it to decompose wood. This knowledge can be used to genetically modify the fungus to optimize decomposition processes and improve the properties of wood.
A new method has revealed a vast diversity of metal-containing proteins in organisms, with implications for understanding protein structure and function. The discovery is expected to lead to important breakthroughs in biological processes, disease detection, and the development of new drugs.
The DOE Joint Genome Institute has sequenced and published the genomes of two wood-decaying fungi, advancing biofuels prospects. Studying the genome of Schizophyllum commune reveals a diverse set of enzymes involved in plant biomass degradation, offering opportunities for efficient biomass conversion into biofuel.
A new virus has been identified as a potential cause of Heart and Skeletal Muscle Inflammation (HSMI) in farmed Atlantic salmon, threatening both farmed and wild populations. The study found the virus, related to reoviruses, in 24.2% of wild salmon samples and 96.5% of infected farmed fish.
Researchers have sequenced the genome of Volvox carteri, a multicellular alga that captures light energy through photosynthesis. The study reveals surprising similarities and differences between the Volvox and Chlamydomonas genomes, shedding light on the evolution of multicellularity in these algae.
Researchers have discovered two mutations in the PTPN11 gene that cause metachondromatosis, a rare heritable disease. The study's findings suggest that next-gen sequencing may rapidly resolve familial diseases and provide insights into other related syndromes.
Researchers have sequenced the genome of an Amerindian strain of Helicobacter pylori, revealing insights into its evolution and migration to the New World. The study highlights the importance of specific genes in inducing inflammation and disease, with a key role for a cytotoxin-associated gene known as cagA.
Researchers successfully sequenced the brown algal genome, revealing genes essential for multicellular life and photosynthesis. The study provides insights into the evolution of higher life on Earth.
The study successfully sequenced the genome of Pseudomonas savastanoi, a pathogenic bacteria causing tuberculosis in olive trees. This achievement paves the way for identifying genes responsible for virulence and developing targeted strategies to combat the disease.
The DOE JGI's new QC tool, GenePRIMP, helps check the quality of microbial genomic DNA sequences, reducing errors in gene annotations. With its ability to identify and correct anomalies, GenePRIMP facilitates comparative analysis and improves the overall accuracy of structural annotations.
Researchers have found a statistically significant association between enteroviral infection and diagnosis of type-1 diabetes in children, with 83% of patients testing positive for enteroviral DNA. The study suggests that different enterovirus types may represent a significant biomarker for early-stage juvenile diabetes.
Researchers found ultra-small microbes, dubbed ARMAN, with tiny genomes and unusual interactions with other Archaea, living in acidic mine drainage. The microbes have unique cellular extensions that pierce other cells, blurring the lines between parasitism and symbiosis.
Researchers at Stanford Medicine have used a healthy person's complete genome sequence to predict their risk for dozens of diseases and how they will respond to common medications. The study provides a cumulative risk report that can help physicians make concrete clinical recommendations, improving the efficiency of medicine.
A study by scientists at Stanford and Harvard Universities analyzed a patient's full genome to identify disease risks and unusual drug responses. The analysis revealed variants associated with diseases in the patient's family and conditions not inherited, highlighting the potential of whole-genome sequencing for personalized medicine.
A Purdue University scientist has discovered a long-sought gene that controls soybean stem growth, allowing for the creation of new plant varieties with desirable characteristics. The gene, Dt1, was found to be responsible for determining whether a soybean's stem continues to grow after flowering.
The study provides genomic information that suggests possible intervention targets for further experimental investigation. The genome sequences of the two new bacterial strains will help researchers zero in on the molecular basis of citrus canker, shedding light on why one strain is more virulent than its counterparts.
Researchers analyzed genetic evidence from 139 killer whales and found clear differences among species in the Antarctic and North Pacific. The study suggests that two types of killer whales are separate species, with additional analysis needed to confirm other possible species.
Researchers have identified a gene regulating appetite and explored thyroid-stimulating hormone receptor protein to understand domestication's impact on chickens. The study provides a model for exploring the molecular basis of animal domestication.
Researchers identified a novel sequence bias that regulates genomic expression rates, providing insights into how cells respond to injuries and poisons. This discovery could lead to more efficient production of therapeutic agents and research reagents.
Researchers used high-performance computing to locate small genes missed by scientists, uncovering 380 families of undetected gene families. The study used an ephemeral supercomputer to perform an all-to-all sequence search, reducing the search time from nearly 90 years to just 12 hours.
The Australian zebra finch's genome reveals a complex system for singing, with over 800 genes regulated by the action of singing. The findings may help scientists understand how humans learn language and identify genetic origins of speech disorders like autism, stroke, and stuttering.
Researchers analyzed the zebra finch genome, finding large and complex gene regulatory networks in the brain activated by song communication. The study also discovered non-coding RNAs play a crucial role in regulating gene expression.
A team of researchers has developed a way to identify genetic markers in grapevines that can be linked with specific traits, such as fruit quality and disease resistance. The technology uses modern sequencing approaches to speed up the traditional breeding process, making it more efficient and cost-effective.
UC Irvine researchers have sequenced the Hydra genome, discovering genes linked to Huntington's disease and beta-amyloid plaque formation in Alzheimer's. The genome sequencing advances research on regeneration, stem cells, and patterning, offering potential new treatments for various injuries and diseases.
The completed genome of Naegleria gruberi sheds light on the transition from prokaryotes to eukaryotes, showcasing a single-celled organism with multiple identities. The analysis reveals genes associated with cellular movement and energy production, providing insights into the evolution of eukaryotic organisms.
Researchers sequenced ancient genome from a rare fossil, confirming polar bears are an evolutionarily young species that split from brown bears 150,000 years ago. The study found polar bears adapted rapidly to past climate changes, but their adaptability is uncertain in the face of current and future climate change.
A rare ancient polar bear fossil has yielded essential information about the species' evolutionary history and response to past climate changes. The research confirms that polar bears evolved recently and adapted quickly, with a split from brown bears around 150,000 years ago.
Researchers have identified genomic regions that enabled an ocean-dwelling fish to adapt to freshwater environments in several independently evolved populations. The study, combining new technologies, found similar gene regions across different lakes and populations.
The Pea Aphid's genome sequence provides valuable tools for understanding aphid biology, speciation, and ecological interactions. The sequencing also sheds light on the relationship between aphids and plant viruses, revealing surprising gaps in the insect immune system.
A new DNA sequencing study has shed light on the evolution of flowering plants, revealing relationships between 70% of all plant species and two major groups that split apart over 111 million years ago. The study provides a clearer picture of the deep divergence that led to speciation in these plants.
The genome sequencing of three parasitoid wasp species offers new insights into the genetic mechanisms of evolution and their importance in controlling agricultural pests. The study identifies key genes responsible for venom production and reveals that these proteins have important physiological effects on host cells.
The International Brachypodium Initiative has sequenced the genome of the wild grass Brachypodium distachyon, which shares features with major grass genomes. This provides a genomic navigation system for studying agronomic traits in wheat and barley genomes.
Cold Spring Harbor Protocols presents high-throughput methods for mapping active gene regulatory elements using DNase-seq, and analyzing DNA synthesis with BrdU-IP-chip. These techniques enable genome-wide identification of genetic regulatory elements and analysis of DNA metabolism.
The sequencing of parasitic wasp genomes has revealed over 7,000 genes with recognizable counterparts in humans, offering a new genetic system for studying genetics and evolution. The discovery also highlights the potential of these wasps in controlling pests and producing artificial diets for mass rearing.
The soybean genome shows evidence of two polyploid events, 59 million and 13 million years ago, which resulted in the plant's unusual ability to produce proteins and oils. Most genes are duplicated at chromosome ends, where recombination occurs, and these duplicates have evolved into new genes.
The soybean genome sequence provides a parts list of what it takes to make a soybean plant, identifying genes essential for agronomic traits like protein and oil content. The analysis also revealed targets for modifying output to bolster biodiesel production.
Scientists from CSHL and Hebrew University Medical Center use next-gen sequencing to rapidly identify the mutated TMEM216 gene as the cause of Joubert Syndrome. The study reveals a high carrier rate of 1:92 among Ashkenazi Jews, making it possible to prevent the disease through premarital genetic screening.
Scientists sequenced the soybean genome to understand its genes and improve characteristics. However, duplicated genes present a challenge, with many copies shuffled, making prediction difficult. Genome sequencing eliminates this issue, enabling faster research advancements.
Researchers have sequenced 85% of the soybean genome, providing critical information to improve crop yields, disease resistance, and nutritional content. The discovery includes genes conferring resistance to a devastating disease and mutations that enhance digestibility and phosphorus absorption.
Researchers discovered that human chromosomes can reorganize their territories surprisingly quickly, taking up to 15 minutes to complete, when transitioning from proliferation to quiescence. This rapid process is driven by an energy-driven mechanism involving nuclear actin-myosin motor function.
A new research project will sequence and annotate the sunflower genome to locate genes responsible for agriculturally important traits. The goal is to develop a hybrid variety of sunflower that can thrive in challenging environments, making it suitable for subsistence agriculture in Africa and North America.
The Genomic Encyclopedia of Bacteria and Archaea (GEBA) project explores the vast unknown realm of microbes, sequencing genomes to advance discovery science. The initial volume reveals novel enzymes and biochemical pathways, shedding light on complex microbial processes and their role in biofuels production and bioremediation.
The study, called the Genomic Encyclopedia of Bacteria and Archaea (GEBA), describes the first 56 genomes from a diverse set of microorganisms. It reveals that phylogeny plays a key role in determining where new genes appear and how they spread.
Researchers at Boston University have developed a new DNA sequencing method that reduces the amount of DNA required for analysis, eliminating the need for time-consuming and error-prone DNA amplification. This breakthrough allows for faster and cheaper genome sequencing, enabling the analysis of long DNA strands in one swipe.
Researchers studying the model organism Daphnia pulex found that introns are inserted into the genome far more frequently than predicted, with many sequences of unknown origin. The study identified 'hot spots' for intron insertion and discovered parallel intron gains in independent genotypes.
The USDA has awarded a two-year grant of $908,280 to Virginia Tech and the University of Minnesota to complete sequencing the genome of the domesticated turkey. The project aims to identify genes and functions in the final genome sequence, providing invaluable information for disease prevention.
Microbiologist Louis Tisa received nearly $500,000 to explore the symbiotic relationship between bacteria Frankia and actinorhizal plant Casuarina. The USDA grant aims to enhance the performance of these trees, providing a sustainable solution to soil enrichment.
Researchers from UA and collaborating institutions deciphered the complete genetic code of maize, providing a comprehensive foundation to systematically study maize biology. The achievement aims to breed higher yielding, disease-resistant, and drought-tolerant cultivars.
Research published in Genome Biology found that Mexicans prioritize partners with Native American and European ancestry, while Puerto Ricans prefer those with African and European heritage. Ancestry has a stronger influence on romance than previously thought, with non-random associations of genes across generations.
A team co-led by CSHL scientists published a reference genome of maize, revealing its complex DNA sequence and 'wonderful diversity'. The 2.3 billion base-pair sequence contains over 32,500 genes and provides a detailed reference manual for annotating the genome.
Researchers at the University of Washington successfully used exome sequencing to identify a previously unknown gene responsible for Miller syndrome, a mendelian disorder. This breakthrough study demonstrates the efficiency and potential of this strategy in discovering the genetic basis of rare diseases, which could lead to new therapies.
Researchers developed a statistical technique to scan genomes for specific gene-regulatory regions without prior knowledge of transcription factors. The approach has been experimentally validated in mouse and fruit fly genomes.