Articles tagged with Antigenicity
A study maps how antibodies target a key region of the SARS-CoV-2 spike protein, neutralizing the virus, and how emerging variants escape. Researchers identified three immune escape strategies: disruption, glycan shielding, and conformational remodeling.
The Influenza A(H3N2) subclade K virus is a growing concern due to its antigenic variants and reduced vaccine effectiveness. Researchers emphasize the need for swift responses to protect public health.
The study utilized biocompatible polymethyl methacrylate microspheres for controlled antigen delivery, demonstrating improved immunogenicity of tetanus toxoid. Microsphere formulations showed significant immune response, with optimal polymer concentrations required to meet I.P. requirements.
Researchers developed biocompatible polymethyl methacrylate microspheres for controlled antigen delivery. The formulation resulted in efficient uptake by macrophages and other antigen-presenting cells, eliciting a notable immune response.
A new study aims to enhance and prolong vaccine effectiveness by delivering adjuvants to white blood cells using lipid nanoparticles. The research, led by WVU professor Sharan Bobbala, has the potential to provide broader protection against evolving viruses and multiple diseases.
Researchers found that antibodies against one of the two main domains of the SARS-CoV-2 viral entry machinery elicit a broad antibody response against many variants. This suggests strategies for clinical development of variant-resistant vaccines.
Researchers at FSU have developed sensitive techniques to detect minute traces of nuts in seemingly nut-free processed foods. The findings could help protect sensitive consumers and improve food industry practices.