Articles tagged with Type 2 Diabetes
A new study reveals that individuals with high intake of high-fat dairy products have a 23% lower risk of developing type 2 diabetes compared to those with low consumption. High fat from dairy may explain the protective association between dairy intake and T2D.
Researchers have discovered a pathological process that affects both mice and humans with type 2 diabetes. By analyzing genome, phenome, proteome, and metabolome data, they identified a specific gene on chromosome 2 that plays a crucial role in the development of the disease.
Research published in Diabetologia finds that age at diagnosis is not linked to microvascular complications, while longer diabetes duration increases the risk in younger patients. Effective prevention requires vigilance across all age groups, with intensified surveillance for macrovascular complications in older populations.
A new study published in PLOS ONE suggests that the current way of diagnosing type-2 diabetes using blood glucose levels needs to be revised. The researchers found changes in blood fat metabolites before glucose levels increased, indicating a potential alternative approach for diagnosis and treatment.
A new series published in The Lancet Diabetes & Endocrinology finds that the growing global diabetes epidemic is hampering progress in controlling and eliminating tuberculosis. With over 1 million cases annually, diabetes-associated TB cases are expected to offset the present downward trend in global TB cases by 8% or more by 2035.
A new study published in The FASEB Journal found that identical twins who eat fast food have similar levels of metabolites, regardless of weight. This suggests that genetics and gut microbiota play a crucial role in the development of Type 2 diabetes.
A recent study analyzing bariatric surgery data in Michigan reveals a significant shift towards sleeve gastrectomy (SG) as the most commonly performed procedure. SG became the predominant bariatric surgery procedure for patients with type 2 diabetes and its use increased by 61% between 2008 and 2013.
A new study suggests that a maternal diet low in protein can predispose offspring to type 2 diabetes. Offspring of mothers fed a low protein diet had decreased insulin levels and fewer β cells, leading to defective insulin secretion by adulthood.
Researchers found that high insulin levels foster processes leading to obesity, even in mice given insulin to counter diabetes. Suppressing glucagon action may prevent hyperinsulinemia without causing diabetes.
A new study found that overweight individuals with type 2 diabetes who lose weight through dieting and physical activity can reduce their healthcare costs by an average of over $500 per year. Those in the intensive lifestyle intervention group had fewer hospitalizations, shorter hospital stays, and used fewer prescription medications.
Research found a strong association between low birth weight and type 2 diabetes in African American women, with those born very low weight facing a 40% increased risk. The study's findings shed light on the long-term health effects of low birth weight in this population.
A study found that hospital admission blood glucose levels can predict the risk of developing type 2 diabetes over three years. The risk increases linearly with increasing blood glucose level at admission, with a 1% risk for patients with low glucose and up to 15% for those with high glucose.
A new study published in Diabetologia found that fenofibrate is as effective in treating type 2 diabetes in women as it is in men. The research showed that fenofibrate reduced levels of adverse blood fats and cardiovascular events by 30% in women, compared to 13% in men.
A major study estimates that nearly half of the US adult population will develop type 2 diabetes by age 20, with Hispanic men and non-Hispanic black women facing the highest risk. The study found a significant increase in lifetime risk of diabetes over 26 years, driven by rising rates and longer life expectancy.
A study by Helmholtz Munich found that individuals with high workplace stress and low control have a 45% higher risk of developing type 2 diabetes. The researchers analyzed data from over 5,300 employed individuals and identified the link independently of classic risk factors.
A large-scale study of over 180,000 people found that patients treated with metformin for type 2 diabetes had a small but statistically significant improvement in survival compared to non-diabetics. Meanwhile, those on sulphonylureas experienced reduced survival, even without statistical manipulation.
Researchers found that consuming two servings of pistachios per day lowered vascular constriction during stress and improved neural control of the heart in adults with well-controlled Type 2 diabetes. The pistachio diet also showed improvements in sleep blood pressure, vascular response to stress, and vagal control of the heart.
A new study suggests that consuming whey protein before meals can reduce blood sugar spikes and improve the body's insulin response in individuals with type 2 diabetes. Glucagon-like peptide-1 production is increased, stimulating insulin secretion and reducing glucose rise after meals.
Research suggests that interval walking training increases insulin sensitivity and improves glucose metabolism, leading to better blood sugar control. The study found no significant benefits from continuous walking training, highlighting the potential of interval training as a more effective approach for managing type 2 diabetes.
A new study published in the Journal of Leukocyte Biology suggests that modulation of B cells may effectively treat and/or prevent periodontitis symptoms related to type 2 diabetes. Researchers used a mouse model to demonstrate the B cell-response's viability as a target for pharmacological intervention.
Research suggests that shift work is associated with a heightened risk of developing type 2 diabetes, particularly among men and those working rotating shift patterns. The study found a 37% increased risk for men and a 9% increased risk for all participants compared to working normal office hours.
A team of researchers from UCLA discovered that autophagy, a process that clears damaged proteins, is impaired in people with Type 2 diabetes, leading to the destruction of insulin-producing beta cells. This impairment contributes to the accumulation of toxic IAPP protein.
A high-salt diet doubles the risk of cardiovascular disease in people with diabetes, according to a new study published by The Endocrine Society. Researchers found that poor blood sugar control exacerbates this effect.
A new study by Sanford-Burnham researchers identifies the NBR1 protein as a critical regulator of obesity-induced inflammation, which leads to metabolic disease. The study suggests that blocking this signal may protect against the development of metabolic disease and type 2 diabetes.
A new study suggests that cholesterol-lowering statins may help people with Type 2 diabetes live longer, with a 50% increase in survival rate among those taking statins. The use of statins was the only modifiable risk factor identified to be protective against mortality.
Scientists have observed the creation of temporary intermediate structures during amylin aggregation, which may explain why proteins aggregate into toxic plaques. The new technology using 2D IR spectroscopy helps elucidate the physics and chemistry behind amyloid diseases.
A recent study published in Cell Press found that high levels of a molecule called heme oxygenase-1 (HO-1) are linked to poor metabolic health and an increased risk of type 2 diabetes in obese humans.
A systematic review and meta-analysis suggest that combined aerobic and resistance training is most effective for controlling blood sugar and blood fat profiles in people with type 2 diabetes. However, more high-quality trials are needed to confirm these findings.
The OpT2mise trial found that insulin pumps result in better blood sugar control than multiple daily injections in people with type 2 diabetes. The study showed that patients using the pumps achieved a significantly greater reduction in average blood sugar levels and spent less time in hyperglycaemia.
A new study finds that for many patients with type 2 diabetes, the benefits of treatment are outweighed by the negative impact of side effects like weight gain and frequent insulin shots. The study suggests that individualized treatment recommendations based on patient risk factors and preferences may be a better approach than focusing...
A large-scale study found that young women with Polycystic Ovary Syndrome (PCOS) have a higher incidence and prevalence of type 2 diabetes, even if not overweight. Obesity is not a significant trigger for type 2 diabetes in PCOS patients.
Researchers found that incorporating two ounces of tree nuts into the diet reduced CHD risk factors and 10-year CHD risk. The study's findings suggest that tree nuts can modify the fatty acid profile of adults with type 2 diabetes, contributing to a reduction in CHD risk.
A new clinical trial shows that Roux-en-Y gastric bypass surgery can help obese patients with Type 2 diabetes reduce their risk of heart disease. The study found significant weight loss and improved blood sugar control, blood pressure, and cholesterol levels in the surgical group compared to the lifestyle modification group.
Adults with Type 2 diabetes who undergo sleeve gastrectomy surgery achieve better blood glucose control two years post-surgery compared to those receiving standard medical care. This study highlights the benefits of a surgical approach in improving diabetes outcomes.
Researchers found changes in gut microbiota composition among people with Type 2 diabetes or obesity compared to healthy individuals. The study identified associations between specific bacterial species and metabolic variables such as BMI, hemoglobin A1c, and waist circumference.
Recent research from BUSM sheds light on the regulatory strategies controlling PPARgamma activity in cells, offering potential avenues for developing effective treatments. By targeting specific subsets of PPARgamma target genes, researchers aim to improve insulin sensitivity and combat type 2 diabetes.
A study published in Cell Metabolism reveals that free radical molecules contribute to the development of type 2 diabetes, obesity, and fatty liver disease by inactivating protein tyrosine phosphatases. This inactivation leads to a cascade of events promoting disease progression.
A new study presented at ICE/ENDO 2014 found that adults with Type 2 diabetes who improve their physical fitness have a lower chance of getting chronic kidney disease. The study also showed that exercise can improve kidney function in people with existing kidney damage, providing hope for patients with progressive kidney disease.
A new study found that empagliflozin lowers blood pressure in patients with Type 2 diabetes and hypertension. The drug also reduced blood glucose levels by 0.62-0.65 percentage points, suggesting a potential to reduce cardiovascular events.
A study found that older adults have fewer taste buds, leading to higher fasting blood sugar levels and lower adiponectin levels. The researchers suggest a link between the number of taste buds and glucose metabolism during aging.
A new study found that soy protein supplements containing phytoestrogens do not reduce testosterone levels in men with Type 2 diabetes. Instead, they improve diabetes control and cardiovascular risk factors. The supplements also show promise in reducing the risk of heart disease.
A new study finds that women with polycystic ovary syndrome (PCOS) are at a high risk of developing type 2 diabetes, regardless of their body mass index (BMI). The study analyzed data from over 6,000 women and found that PCOS was associated with a five-fold increased risk of T2DM.
A new study finds that diabetes drug liraglutide, when combined with diet and exercise, leads to significant weight loss of up to 18.7 pounds and reversal of prediabetes in nearly 70% of participants. The medication also delays the development of type 2 diabetes by three times.
A long-term follow-up study found that bariatric surgery resulted in more frequent diabetes remission and fewer complications compared to usual care. The study showed a significant decrease in microvascular and macrovascular complications.
Researchers mapped a gene variant among Greenlanders that markedly increases the risk of developing type 2 diabetes. The gene variant is primarily found in Greenlanders and explains 15% of cases in the country.
Researchers found that interventions for diabetes distress significantly reduced symptoms of depression in people with type 2 diabetes. In contrast, patients with type 1 diabetes who reported high levels of depressive symptoms had a higher mortality risk. These findings suggest that 'diabetes distress' may not be a co-morbid psychiatri...
The study found that participants who received lifestyle intervention or metformin had lower rates of type 2 diabetes development, with reductions of 27% and 17%, respectively. However, the interventions did not reduce microvascular complications such as eye, nerve, and kidney disease.
The Affordable Care Act (ACA) offers significant benefits for diabetes patients, including non-exclusion of pre-existing conditions and access to preventive services. The law also authorizes the creation of the National Diabetes Prevention Program, delivering evidence-based lifestyle change programs to prevent type 2 diabetes.
A study found that improving diet quality by 10% over four years reduced the risk of type 2 diabetes by about 20%. This benefit was independent of other lifestyle changes such as weight loss or increased physical activity. Improving diet quality alone has significant health benefits.
Men with type 2 diabetes lost 12% of abdominal fat and reduced blood sugar levels by 20%, while those with high blood pressure showed improved heart rate and fitness, reducing the risk of heart disease. Football training also provided social benefits and increased motivation for further exercise.
A genetic analysis of 3,700 Mexican and U.S. Latino individuals identified a gene variant associated with a 5-fold increase in type 2 diabetes prevalence. The HNF1A gene variant was found to be more common in participants with type 2 diabetes, particularly in Latino patients.
A long-term follow-up of obese patients with type 2 diabetes shows that bariatric surgery leads to more frequent diabetes remission. The study found that bariatric surgery results in a lower incidence of microvascular and macrovascular complications compared to usual care.
Researchers identified a strong genetic risk factor for type 2 diabetes that primarily affects Latin American patients, with potential implications for tailored treatments. The study's findings suggest that patients carrying this variant may benefit from drugs effective in treating MODY, a rare form of diabetes.
Use of insulin analogs among privately insured patients with type 2 diabetes increased significantly between 2000 and 2010. Out-of-pocket expenditures for insulin prescriptions also rose substantially during this period.
Researchers discovered altered salivary biomarker levels in obese children, indicating a potential non-invasive method for identifying early Type 2 diabetes risk. The study's findings provide valuable insights into childhood obesity and metabolic syndrome, paving the way for development of prevention strategies.
Two recent JAMA Surgery studies investigate bariatric surgery as a treatment option for type 2 diabetes in obese patients. The studies found that bariatric surgery can lead to significant weight loss and improvements in blood sugar control, suggesting it may be an effective adjunctive therapy for managing the condition.
A study published in Human Reproduction found that mothers of daughters with polycystic ovary syndrome (PCOS) have a significantly increased risk of death, especially when combined with type 2 diabetes. The research compared mortality rates between mothers and fathers of PCOS daughters with the general Dutch population.
Researchers at the University of Montreal have identified a novel enzyme, ABHD6, that breaks down a fat-like signal involved in insulin release. Inhibiting this enzyme may increase insulin levels in blood and improve sensitivity to insulin, providing a potential new target for type 2 diabetes treatment.
A new study found that online therapeutic communities can foster empathy and peer-to-peer mentoring among people living with chronic disease. Interactive social platforms build community engagement and markets for new technologies, supporting healthcare reform.
A study found a fat-storage gene mutation that interferes with key enzyme in lipid metabolism, increasing diabetes risk. The mutation affects 5.1% of the Old Order Amish study participants, with four individuals having two copies of the mutation.