Articles tagged with Sars Cov 2
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A new review suggests zinc can reduce the duration of acute viral respiratory tract infections like the common cold and flu. Zinc use has also been linked to reducing symptom severity, particularly during peak illness days.
Researchers developed a new online portal, DINC-COVID, to speed up the identification of potential pandemic treatments. The platform incorporates models of three drug targets and uses ensemble docking to score ligands' success in binding.
Researchers developed a viral panel that enables simultaneous testing for SARS-CoV-2 and common respiratory viruses, providing insight into coinfections and viral spread. The tool helps predict and mitigate future outbreaks by tracking novel viral variants and their patterns of spread.
A new study found that monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from SARS-CoV-2 disease by reducing signs of inflammation. The treatment prevented viral RNA in the cerebrospinal fluid and infiltration of activated immune cells, suggesting a potential preventative measure for elderly residents during outbreaks.
A recent study published in JAMA Pediatrics found that children and adults have similar risks of becoming infected with SARS-CoV-2. However, a larger proportion of infected children do not show symptoms of COVID-19, highlighting the need for continued public health safety measures.
Researchers at Johns Hopkins Medicine found that antibody levels against SARS-CoV-2 stay higher in people who were infected by the virus and then received protection from mRNA vaccine compared to those who only got vaccinated. A longer interval between virus exposure and first vaccine dose may enhance antibody response.
A team of scientists has identified a compound that shows promise in easing COVID-19 symptoms by targeting the cellular quality-control system damaged by coronaviruses. The compound, AMG PERK 44, was found to halt virus replication and boost lung function in mice infected with MERS.
A massive Israeli study found that a third COVID-19 vaccine dose reduces hospitalization and severe disease risks by up to 93% compared to two doses. The research provides valuable insights into the effectiveness of booster shots in real-world settings.
A study by Texas A&M University researchers analyzed contact tracing data and found that most player interactions were fleeting and brief. Only a small number of games had prolonged close contacts, with none resulting in COVID-19 cases among athletes.
Researchers develop cellular models to study SARS-CoV-2 infection of the inner ear, finding that the virus can infect hair cells and Schwann cells. The pattern of infection matches symptoms observed in a study of 10 Covid-19 patients with ear-related issues.
A clinical trial of 465 patients found that administering heparin in therapeutic doses reduced mortality from COVID-19 by 78%, with benefits only observed when administered between seven and 14 days after symptom onset. The study suggests that timing is crucial for treatment efficacy.
A study of 64 college football games found no instances of in-game SARS-CoV-2 transmission. Researchers analyzed contact exposures among opposing team players, concluding that social distancing measures may have played a role in preventing transmission.
A review and meta-analysis of 32 studies involving 4,900 participants found that SARS-CoV-2 vaccination response was lower in patients with end-stage kidney disease receiving dialysis. Diabetes may be a risk factor for nonresponse to vaccination.
Researchers have discovered a potential new treatment for COVID-19 by targeting the pentose phosphate pathway, which is necessary for SARS-CoV-2 replication. The study found that inhibiting this pathway with benfooxythiamine suppresses viral replication and reduces virus production.
A national study in Sweden suggests that the risk of adverse pregnancy outcomes from SARS-CoV-2 is likely lower than previously feared. The study found that infants born to test-positive mothers had a higher risk of neonatal care and preterm birth, but no significant difference in stillbirths or low Apgar scores.
A UBC-led research team discovered that SARS-CoV-2 attaches to and deactivates galectin-8, a sensor protein that protects cells against infection. By disabling this defense system, the virus can hijack host cells to produce more viruses.
Researchers identified two nanobodies that specifically target and stabilize the tetrameric form of SARS-CoV-2 non-structural protein Nsp9, potentially repressing viral replication. These findings suggest a new antiviral strategy for diagnosis and treatment against COVID-19.
Researchers from the University of Queensland found that COVID-19 causes cardiovascular complications due to inflammation in infected airway cells. The study clarifies a key debate about the relationship between the virus and blood vessel linings, suggesting inflammation as the primary cause of damage.
A recent Johns Hopkins Medicine-led study suggests that statin use is not beneficial for reducing COVID-19 mortality or severity. Instead, patients taking statins had an increased risk of developing a more severe form of the disease. The researchers found no significant impact on mortality rates.
Researchers developed a novel sensor that can detect SARS-CoV-2 proteins without antibodies, giving results within minutes. The technology enables rapid diagnostics for Covid-19 and future pandemics, reducing economic loss.
Researchers have discovered a more effective treatment for children with Kawasaki disease and multisystem inflammatory syndrome in children (MIS-C), a rare COVID-19 reaction. The new therapy, infliximab, reduces fever duration, hospitalizations, and anemia compared to standard IVIG treatment.
A Brazilian study demonstrates that a hyperimmune serum consisting of purified antibody fragments produced in horses can be an efficient approach to combat covid-19. The neutralizing activity of the sera has been proved to be high against the P.1 (Gamma) and P.2 variants, improving animal clinical conditions in hamsters.
Researchers developed a device that uses light to manipulate and isolate individual viruses, enabling precise diagnosis, treatment, and study of viruses. The device has the potential to aid in vaccine development and research on SARS-CoV-2 virus, allowing for targeted analysis of specific virus mutants.
The Delta variant is the most infectious known to date due to its ability to fuse with cells quickly and efficiently. Researchers found that Delta's spike protein has a unique property that accounts for its transmissibility, making it a favorable target for next-generation vaccines and treatments.
Scientists at the University of Colorado School of Medicine have identified specific genetic biomarkers in blood samples that can indicate the severity of COVID-19. The study's findings suggest that these signals can be used to monitor SARS-CoV-2 status and predict clinical outcomes.
A study of young Swedish adults found that over one in four had SARS-CoV-2-specific antibodies, but fewer had measurable levels of memory B and T cells compared to other age groups. The researchers will continue to study long COVID and vaccination effects on immunity.
Researchers discovered that SARS-CoV-2 causes an early release of the immune-dampening TGFβ messenger, disrupting the innate immune response. This disruption impairs natural killer cells' ability to eliminate virus-infected cells, leading to severe disease.
Researchers discovered that a lower dose of the first shot, followed by a full-dose booster, significantly improved SARS-CoV-2 vaccine potency in mice. This approach, which involves an extended prime-boost interval, may lead to more robust and durable immune responses.
Researchers from Osaka University found that SARS-CoV-2 binds to a cell-surface protein whose expression is promoted by high blood insulin levels in older, obese, and diabetic individuals. Regulating blood insulin levels may help lower COVID-19 risk by reducing GRP78 expression.
Researchers at Penn State used traffic cameras and mobile device data to monitor COVID-19 cases in Centre County, PA. Movement data preceded increases in cases, suggesting that behavioral interventions like stay-at-home orders can be effective in controlling transmission.
Researchers detected SARS-CoV-2 viral load in wastewater samples that correlated with reported COVID-19 cases. The study suggests wastewater-based epidemiology as a valuable tool for early warning detection during outbreaks.
A new study by ISGlobal provides robust evidence that COVID-19 is a seasonal infection linked to low temperatures and humidity. The research team found a negative relationship between the transmission rate of SARS-CoV-2 and both temperature and humidity at the global scale.
A survey of 299 adults and three experiments with over 1,324 participants found that 86% would get vaccinated if required for work, travel, or school. Vaccination requirements strengthened intentions to vaccinate, even among those who tend to react negatively to regulations.
A study published in the Atlantic Journal of Communication analyzed Instagram posts from 20 celebrity influencers about COVID-19 between March and May 2020. The researchers found that celebrities initially modeled guidance from health experts, normalizing suggested behaviors such as staying home and practicing hand hygiene.
A modelling study suggests that COVID-19 could lead to the collapse of a population of mountain gorillas living in Volcanoes National Park. The risk is higher due to lower availability of treatments for gorillas, but measures like mask-wearing and vaccination can limit transmission.
A new study from the University of Southampton demonstrates a safe method to clean and reuse facemask respirators using advanced low-temperature plasma technology. This technique can remove 99.99% of coronavirus while maintaining filter performance, reducing plastic waste by approximately 70%.
A study of cross-cultural differences in COVID-19 knowledge and attitudes found that people in Europe and the US had the lowest knowledge and adherence to safety measures. In contrast, people in the Middle East and Asia were more aware of COVID-19 and took greater precautions.
A new study from Karolinska Institutet finds that two vaccine doses increase antibody levels in the airways after COVID-19, while a second dose after recovery also boosts levels. The results highlight the importance of completing vaccination with a second dose to achieve optimal immune responses and reduce transmission.
Researchers created EpiPolicy software system to model epidemics, maximizing public health protections while minimizing economic and social costs. The model uses Monte Carlo and reinforcement learning techniques to design intervention strategies automatically, taking into account risk and uncertainty.
Researchers at West Virginia University discovered a significant relationship between Christian nationalism and vaccine hesitancy, citing a national sample of 2,000 U.S. adults. They found that individuals embracing this ideology are less likely to receive the COVID-19 vaccine and express skepticism towards science.
Scientists have created sustainable face masks made from biodegradable PLA, which breaks down quickly under ambient temperatures. The study showed that the masks can be fully bio-mineralized without forming secondary microplastic pollution, paving the way for more eco-friendly alternatives.
A new study published in Science Translational Medicine found that male placentas have increased immune activation and receive fewer anti-COVID antibodies from their mothers. This may help protect male fetuses but pose risks to the fetus and child.
A study of 5,000 simulated undergraduates found that weekly surveillance testing was associated with a substantial reduction in infections. Even at low vaccine effectiveness rates, quarantine protocols were effective in reducing infections by up to 93.6%.
Researchers at Georgia Institute of Technology have developed a flow control technology to overcome limitations of traditional dipstick tests. This technology enables complex biomedical assays and can detect multiple pathogens, including SARS-CoV-2 and influenza viruses.
Patients with multiple myeloma often mount a poor antibody response to COVID-19 vaccines and have a weak T cell response, underscoring the need for booster vaccination and safety precautions. Researchers found that these patients are at high risk of severe COVID-19 infection.
Researchers at the University of Arizona developed a new curriculum that allows high school students to learn about coronaviruses, genetics, and bioinformatics from home. The lesson plan, which was created before COVID-19 vaccines were introduced, teaches students how different vaccines work and analyzes protein sequences. Students who...
A recent study published in Tourism Management explores travelers' attitudes toward pre-travel vaccination requirements. The researchers found that willingness to vaccinate and beliefs that others should vaccinate are key predictors of support for vaccine mandates. Travelers who had previously tested positive for COVID-19 or traveled m...
Researchers compared immune responses elicited by three COVID-19 vaccines over an eight-month follow-up period. The mRNA vaccines showed high peak antibody responses that declined sharply, while the single-shot Ad26 vaccine induced lower initial antibody responses but stable levels over time.
A study by Northwestern University scientists has shown that coronavirus vaccines and prior infections can provide broad immunity against other, similar coronaviruses. The findings build a rationale for universal coronavirus vaccines.
The research team aims to understand the mechanisms that contribute to long-term consequences of COVID-19 infection, particularly in women who may be disproportionally affected by chronic symptoms. They plan to leverage a biorepository and longitudinal study to assess the impact of acute and chronic inflammation on brain injury and neu...
Researchers found that Delta and Delta Plus infect lung cells with higher efficiency than the original virus, evading antibodies induced by infection and vaccination. The new variants were also resistant to some therapeutic antibodies, leading to reduced inhibition.
The COVID-19 pandemic has led to reduced influenza reporting, but vaccination and strengthened surveillance are critical for a possible resurgence. Research highlights the importance of flu vaccination and early testing for non-influenza respiratory viruses.
A severe COVID-19 outbreak in Delhi, India, highlights the challenge of reaching herd immunity due to the Delta variant's transmissibility and ability to infect previously infected individuals. Mathematical modeling and genomic analysis suggest the Delta variant is 30-70% more contagious than previous lineages.
The study analyzed SARS-CoV-2 genomic surveillance data from England, identifying key variants like Alpha and Delta that changed the course of the epidemic. These variants led to significant growth advantages, with Delta's growth rate being 59% higher than Alpha's, more than doubling the average growth rate of the virus.
A study published in the Journal of Infectious Diseases found that children can carry high levels of live, replicating SARS-CoV-2 virus in their respiratory secretions, with no correlation between age and viral load. The researchers also noted that viral loads are highest early in the illness in both symptomatic and asymptomatic children.
Pooled saliva sample COVID-19 testing demonstrated over 95% agreement with the gold standard and detected 83% of semester's cases. The approach is among the most sensitive available, detecting virus at very low viral load, and provides results in under 8 hours.
A large Swedish cohort study found that obese patients (BMI >35 kg/m2) were twice as likely to experience a prolonged ICU stay or die from COVID-19. The study also showed that obesity is an independent risk factor for severe outcomes, suggesting closer monitoring for individuals with obesity hospitalized for COVID-19.
Researchers have identified a highly potent antibody that effectively blocks the spike protein of SARS-CoV-2, halting viral replication and enabling the immune system to eliminate the virus. This breakthrough discovery offers a potential preventive-treatment option for unvaccinated individuals or those with weakened immune systems.
Researchers investigated possible role of children in SARS-CoV-2 transmission using data from a Belgian primary school. The study found that children who tested positive for COVID-19 could transmit the virus to others after symptoms had resolved.
A study of 1,236 participants in 310 households found that SARS-CoV-2 infection risks were similar between children and adults, regardless of household contact. The study provides insights into the clinical characteristics of SARS-CoV-2 infection among both age groups.