Articles tagged with Sars Cov 2
A French study of nearly 27,000 individuals found that persistent physical symptoms like fatigue and breathlessness after COVID-19 may be more closely tied to beliefs about having been infected than actual lab confirmation. The research suggests a possible psychological component to lingering symptoms.
Researchers developed a human Intestine Chip to study coronavirus infection and test potential treatments. The chip showed that nafamostat reduced virus presence while remdesivir damaged intestinal tissue, offering insights into underlying causes of GI symptoms and improving understanding of treatment efficacy and toxicity.
A process in cells may limit SARS-CoV-2 infectivity, but mutations in alpha and delta variants overcome this effect. GALNT1 enzyme activity reduces furin cleavage, while mutated spike proteins increase it.
Regular testing of asymptomatic healthcare workers identified as cost-efficient strategy to prevent SARS-CoV-2 transmission. The study suggests that desynchronization of teams had limited effectiveness due to economic constraints.
A study at the University of São Paulo found that Torquetenovirus (TTV) titer is higher in people infected by SARS-CoV-2, suggesting it could be a biomarker for COVID-19 severity. TTV load correlates with disease progression and outcome, and its measurement may support diagnosis.
Researchers found a clear link between people's expectations and actual vaccine side effects, suggesting that psychological factors can predict which individuals will experience more symptoms. The study aims to help overcome lingering vaccine hesitancy by reframing the way we think about side effects.
Researchers will identify and track SARS-CoV-2 variants using genomic sequence analyses. The project aims to understand the emergence and spread of the virus in West Virginia, helping public health officials prepare for future outbreaks.
A national survey found that half of US vaccine hesitant individuals believe nothing will convince them to get vaccinated. Most cited concerns about vaccine safety as the reason for their unwillingness.
Researchers at UC San Diego have created a CRISPR-based rapid diagnostic technology that detects SARS-CoV-2, the coronavirus causing COVID-19. The new SENSR system is designed to simplify SARS-CoV-2 detection with a goal of eventual adaptation for in-home use.
A study of 21 mothers found that those infected with SARS-CoV-2 during pregnancy had a varied immune response in their newborns, resulting in some infants developing antibodies and others not.
A team of experts from Tel Aviv University has identified 5 coronavirus proteins responsible for damaging blood vessels. The researchers hope that the identification will lead to the development of targeted drugs that reduce vascular damage in COVID-19 patients.
Research reveals SARS-CoV-2 can enter the brain and affect neural function, leading to symptoms like headache, depression, and fatigue. Many people experience lingering cognitive or neurological problems months after initial recovery.
A new poll reveals that most people over 50 have received or plan to receive flu shots, with a majority also planning to get additional COVID-19 vaccine doses. The poll highlights differences in vaccine attitudes among older adults of different age groups and backgrounds.
Scientists have engineered enzymes to manufacture molnupiravir, resulting in a shorter and higher-yielding synthesis. The new method reduces the risk of hospitalization and death from COVID-19 for newly diagnosed patients, showing promise as an antiviral treatment.
A study of 8,889 vaccinated patients and 88,898 unvaccinated patients found the Ad26.COV2.S vaccine to be effective in reducing SARS-CoV-2 infection. The results support mass vaccination efforts globally amid variant spread.
A new review suggests zinc can reduce the duration of acute viral respiratory tract infections like the common cold and flu. Zinc use has also been linked to reducing symptom severity, particularly during peak illness days.
Researchers developed a new online portal, DINC-COVID, to speed up the identification of potential pandemic treatments. The platform incorporates models of three drug targets and uses ensemble docking to score ligands' success in binding.
Researchers developed a viral panel that enables simultaneous testing for SARS-CoV-2 and common respiratory viruses, providing insight into coinfections and viral spread. The tool helps predict and mitigate future outbreaks by tracking novel viral variants and their patterns of spread.
A new study found that monoclonal antibodies protected aged, diabetic rhesus macaque monkeys from SARS-CoV-2 disease by reducing signs of inflammation. The treatment prevented viral RNA in the cerebrospinal fluid and infiltration of activated immune cells, suggesting a potential preventative measure for elderly residents during outbreaks.
A recent study published in JAMA Pediatrics found that children and adults have similar risks of becoming infected with SARS-CoV-2. However, a larger proportion of infected children do not show symptoms of COVID-19, highlighting the need for continued public health safety measures.
Researchers at Johns Hopkins Medicine found that antibody levels against SARS-CoV-2 stay higher in people who were infected by the virus and then received protection from mRNA vaccine compared to those who only got vaccinated. A longer interval between virus exposure and first vaccine dose may enhance antibody response.
A team of scientists has identified a compound that shows promise in easing COVID-19 symptoms by targeting the cellular quality-control system damaged by coronaviruses. The compound, AMG PERK 44, was found to halt virus replication and boost lung function in mice infected with MERS.
A massive Israeli study found that a third COVID-19 vaccine dose reduces hospitalization and severe disease risks by up to 93% compared to two doses. The research provides valuable insights into the effectiveness of booster shots in real-world settings.
A study by Texas A&M University researchers analyzed contact tracing data and found that most player interactions were fleeting and brief. Only a small number of games had prolonged close contacts, with none resulting in COVID-19 cases among athletes.
Researchers develop cellular models to study SARS-CoV-2 infection of the inner ear, finding that the virus can infect hair cells and Schwann cells. The pattern of infection matches symptoms observed in a study of 10 Covid-19 patients with ear-related issues.
A clinical trial of 465 patients found that administering heparin in therapeutic doses reduced mortality from COVID-19 by 78%, with benefits only observed when administered between seven and 14 days after symptom onset. The study suggests that timing is crucial for treatment efficacy.
A study of 64 college football games found no instances of in-game SARS-CoV-2 transmission. Researchers analyzed contact exposures among opposing team players, concluding that social distancing measures may have played a role in preventing transmission.
A review and meta-analysis of 32 studies involving 4,900 participants found that SARS-CoV-2 vaccination response was lower in patients with end-stage kidney disease receiving dialysis. Diabetes may be a risk factor for nonresponse to vaccination.
Researchers have discovered a potential new treatment for COVID-19 by targeting the pentose phosphate pathway, which is necessary for SARS-CoV-2 replication. The study found that inhibiting this pathway with benfooxythiamine suppresses viral replication and reduces virus production.
Researchers identified two nanobodies that specifically target and stabilize the tetrameric form of SARS-CoV-2 non-structural protein Nsp9, potentially repressing viral replication. These findings suggest a new antiviral strategy for diagnosis and treatment against COVID-19.
Researchers from the University of Queensland found that COVID-19 causes cardiovascular complications due to inflammation in infected airway cells. The study clarifies a key debate about the relationship between the virus and blood vessel linings, suggesting inflammation as the primary cause of damage.
A national study in Sweden suggests that the risk of adverse pregnancy outcomes from SARS-CoV-2 is likely lower than previously feared. The study found that infants born to test-positive mothers had a higher risk of neonatal care and preterm birth, but no significant difference in stillbirths or low Apgar scores.
A UBC-led research team discovered that SARS-CoV-2 attaches to and deactivates galectin-8, a sensor protein that protects cells against infection. By disabling this defense system, the virus can hijack host cells to produce more viruses.
Researchers have discovered a more effective treatment for children with Kawasaki disease and multisystem inflammatory syndrome in children (MIS-C), a rare COVID-19 reaction. The new therapy, infliximab, reduces fever duration, hospitalizations, and anemia compared to standard IVIG treatment.
A Brazilian study demonstrates that a hyperimmune serum consisting of purified antibody fragments produced in horses can be an efficient approach to combat covid-19. The neutralizing activity of the sera has been proved to be high against the P.1 (Gamma) and P.2 variants, improving animal clinical conditions in hamsters.
Researchers developed a device that uses light to manipulate and isolate individual viruses, enabling precise diagnosis, treatment, and study of viruses. The device has the potential to aid in vaccine development and research on SARS-CoV-2 virus, allowing for targeted analysis of specific virus mutants.
The Delta variant is the most infectious known to date due to its ability to fuse with cells quickly and efficiently. Researchers found that Delta's spike protein has a unique property that accounts for its transmissibility, making it a favorable target for next-generation vaccines and treatments.
Scientists at the University of Colorado School of Medicine have identified specific genetic biomarkers in blood samples that can indicate the severity of COVID-19. The study's findings suggest that these signals can be used to monitor SARS-CoV-2 status and predict clinical outcomes.
A recent Johns Hopkins Medicine-led study suggests that statin use is not beneficial for reducing COVID-19 mortality or severity. Instead, patients taking statins had an increased risk of developing a more severe form of the disease. The researchers found no significant impact on mortality rates.
Researchers developed a novel sensor that can detect SARS-CoV-2 proteins without antibodies, giving results within minutes. The technology enables rapid diagnostics for Covid-19 and future pandemics, reducing economic loss.
Researchers discovered that a lower dose of the first shot, followed by a full-dose booster, significantly improved SARS-CoV-2 vaccine potency in mice. This approach, which involves an extended prime-boost interval, may lead to more robust and durable immune responses.
Researchers from Osaka University found that SARS-CoV-2 binds to a cell-surface protein whose expression is promoted by high blood insulin levels in older, obese, and diabetic individuals. Regulating blood insulin levels may help lower COVID-19 risk by reducing GRP78 expression.
Researchers at Penn State used traffic cameras and mobile device data to monitor COVID-19 cases in Centre County, PA. Movement data preceded increases in cases, suggesting that behavioral interventions like stay-at-home orders can be effective in controlling transmission.
A study of young Swedish adults found that over one in four had SARS-CoV-2-specific antibodies, but fewer had measurable levels of memory B and T cells compared to other age groups. The researchers will continue to study long COVID and vaccination effects on immunity.
Researchers discovered that SARS-CoV-2 causes an early release of the immune-dampening TGFβ messenger, disrupting the innate immune response. This disruption impairs natural killer cells' ability to eliminate virus-infected cells, leading to severe disease.
Researchers detected SARS-CoV-2 viral load in wastewater samples that correlated with reported COVID-19 cases. The study suggests wastewater-based epidemiology as a valuable tool for early warning detection during outbreaks.
A new study by ISGlobal provides robust evidence that COVID-19 is a seasonal infection linked to low temperatures and humidity. The research team found a negative relationship between the transmission rate of SARS-CoV-2 and both temperature and humidity at the global scale.
A survey of 299 adults and three experiments with over 1,324 participants found that 86% would get vaccinated if required for work, travel, or school. Vaccination requirements strengthened intentions to vaccinate, even among those who tend to react negatively to regulations.
A study published in the Atlantic Journal of Communication analyzed Instagram posts from 20 celebrity influencers about COVID-19 between March and May 2020. The researchers found that celebrities initially modeled guidance from health experts, normalizing suggested behaviors such as staying home and practicing hand hygiene.
A modelling study suggests that COVID-19 could lead to the collapse of a population of mountain gorillas living in Volcanoes National Park. The risk is higher due to lower availability of treatments for gorillas, but measures like mask-wearing and vaccination can limit transmission.
A new study from the University of Southampton demonstrates a safe method to clean and reuse facemask respirators using advanced low-temperature plasma technology. This technique can remove 99.99% of coronavirus while maintaining filter performance, reducing plastic waste by approximately 70%.
A study of cross-cultural differences in COVID-19 knowledge and attitudes found that people in Europe and the US had the lowest knowledge and adherence to safety measures. In contrast, people in the Middle East and Asia were more aware of COVID-19 and took greater precautions.
A new study from Karolinska Institutet finds that two vaccine doses increase antibody levels in the airways after COVID-19, while a second dose after recovery also boosts levels. The results highlight the importance of completing vaccination with a second dose to achieve optimal immune responses and reduce transmission.
Researchers created EpiPolicy software system to model epidemics, maximizing public health protections while minimizing economic and social costs. The model uses Monte Carlo and reinforcement learning techniques to design intervention strategies automatically, taking into account risk and uncertainty.
Researchers at West Virginia University discovered a significant relationship between Christian nationalism and vaccine hesitancy, citing a national sample of 2,000 U.S. adults. They found that individuals embracing this ideology are less likely to receive the COVID-19 vaccine and express skepticism towards science.
Scientists have created sustainable face masks made from biodegradable PLA, which breaks down quickly under ambient temperatures. The study showed that the masks can be fully bio-mineralized without forming secondary microplastic pollution, paving the way for more eco-friendly alternatives.
A new study published in Science Translational Medicine found that male placentas have increased immune activation and receive fewer anti-COVID antibodies from their mothers. This may help protect male fetuses but pose risks to the fetus and child.
A study of 5,000 simulated undergraduates found that weekly surveillance testing was associated with a substantial reduction in infections. Even at low vaccine effectiveness rates, quarantine protocols were effective in reducing infections by up to 93.6%.
Researchers at Georgia Institute of Technology have developed a flow control technology to overcome limitations of traditional dipstick tests. This technology enables complex biomedical assays and can detect multiple pathogens, including SARS-CoV-2 and influenza viruses.
Patients with multiple myeloma often mount a poor antibody response to COVID-19 vaccines and have a weak T cell response, underscoring the need for booster vaccination and safety precautions. Researchers found that these patients are at high risk of severe COVID-19 infection.