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Dehydration’s role in learning and memory

Researchers at Cold Spring Harbor Laboratory discovered how dehydration enables calcium to pass through the NMDAR channel, revealing key molecular mechanisms underlying learning and memory. This finding has implications for brain development and disease, including GRIN disorders that cause severe developmental disabilities.

SourceCold Spring Harbor Laboratory·JournalNature Neuroscience·DateMay 18, 2026

Keep the cool feeling: A lipid enzyme for maintaining cool temperature sensation and avoidance

Researchers have identified a monoacylglycerol acyltransferase (MGAT)-coding gene named bishu-1 that maintains the expression level of thermal receptors and modulates cool temperature sensation and avoidance behavior. The discovery could promote the development of lipid-mediated treatments for maintaining thermosensation in humans.

SourceNational Institutes of Natural Sciences·JournalCommunications Biology·TypeExperimental study·DateMay 29, 2025