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Life Sciences

Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.

447,757 articles | 2542 topics

Health and Medicine

Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.

431,843 articles | 751 topics

Social Sciences

Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.

260,756 articles | 745 topics

Physical Sciences

Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.

257,913 articles | 1552 topics

Applied Sciences and Engineering

Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.

225,386 articles | 998 topics

Scientific Community

Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.

193,043 articles | 157 topics

Space Sciences

Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.

29,662 articles | 175 topics

Research Methods

Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.

21,889 articles | 139 topics

Mathematics

Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.

3,023 articles | 113 topics

How a metamaterial might improve a depression treatment

A new headpiece design could improve a depression treatment by allowing researchers to hit finer targets in the brain, up to twice as deep as today's systems. The system uses computer simulations and metamaterials to reduce pain and increase effectiveness.

How neurons get wired

Researchers found that embryonic nerve cells use two versions of a signaling molecule to determine which end is the axon and which is the dendrite. This discovery could help improve therapies for spinal cord injuries and neurodegenerative diseases.

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SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Chips that mimic the brain

Researchers developed a neuromorphic system that can carry out complex sensorimotor tasks in real time, exhibiting cognitive abilities. The system combines artificial neurons into networks that implemented neural processing modules, closely resembling mammalian brain structures.

Brandeis scientist wins 2013 Gruber Foundation Neuroscience Prize

Eve Marder's pioneering work in understanding the nervous system has helped redefine how we think about neurons and their capabilities. Her research using crustaceans has also shed light on conditions like depression, showing that imbalances in neuromodulation are key factors.

Scientists map the wiring of the biological clock

Researchers have discovered a push-pull system in the suprachiasmatic nucleus (SCN) that allows the biological clock to adjust to changes in day/night cycles. The system uses neurotransmitters GABA and VIP to synchronize neurons and maintain accuracy within minutes of the day.

Mathematicians help to unlock brain function

Researchers from Queen Mary University of London used complex networks to map human brain connections, finding symmetrical neurons may drive synchronized activity across distant regions. This breakthrough adds to recent findings on neural network growth and development.

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Davis Instruments Vantage Pro2 Weather Station offers research-grade local weather data for networked stations, campuses, and community observatories.

Chemist Bozhi Tian selected as 2013 Searle Scholar

Bozhi Tian has been selected as a 2013 Searle Scholar for his innovative research on single-neuron dynamics and bioelectric circuits. He will use the grant to develop silicon-based biomaterials, with a long-term goal of understanding neurodegenerative diseases.

Pavlov's rats? Rodents trained to link rewards to visual cues

Researchers discovered that brain connections in the vision-processing center can be strengthened by acetylcholine, allowing animals to associate visual cues with rewards. The study found that nerve cells in the primary visual cortex develop molecular memories, enabling animals to predict rewarding outcomes.

Pair of proteins gets brain cells into shape

Researchers identified ADF and cofilin as crucial proteins in the shape change of young brain cells, enabling them to develop connections with other cells. The study found that these proteins facilitate neurite formation, which is essential for brain development and regeneration.

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Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Neural interaction in periods of silence

Researchers have developed a novel methodology called NET-fMRI to map widespread neural networks activated by local events. The study reveals that short periods of recurrent ripples in the brain are closely associated with reproducible cortical activations and extensive activity suppression in other brain structures.

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Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

This is your brain on freestyle rap

Researchers scanned the brains of 12 freestyle rap artists to study their brain activity during improvisation. The findings show that freestyling increases brain activity in areas responsible for motivation, language, and emotion, allowing for a unique flow of thoughts and words.

Empathy represses analytic thought, and vice versa

A study led by Anthony Jack from Case Western Reserve University shows that the brain fires up one network for empathy and suppresses another for analysis, limiting their simultaneous use. This finding suggests established theories about two competing networks in the brain must be revised.

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Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Triangles guide the way for live neural circuits in a dish

Researchers at KAIST used triangular shapes to guide axon growth in a dish, finding that smaller vertices were more effective in inducing growth. The study aims to develop a reproducible neural circuit model for learning and memory studies as well as drug screening applications.

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Neuro researchers sharpen our understanding of memories

Researchers have gained a better understanding of how precise memories are formed through the study of inhibitory neurons. The discovery sheds light on the neurobiological basis of memory problems in neurodegenerative disorders like Alzheimer's disease, and could potentially lead to new treatments.

New models predict patterns of brain damage in dementia

Two studies published in Neuron have developed groundbreaking models that predict the landscape of degeneration in various forms of dementia. The models, which focus on structural and functional connectivity networks, suggest that dementias target specific networks of neurons linked by connectivity rather than spatial proximity.

How the brain cell works: A dive into its inner network

A team led by University of Miami professor Akira Chiba has developed a novel methodology to examine protein-protein interactions in the fruit fly, allowing for the creation of a point-by-point map of these interactions. This breakthrough uses custom-built 3D FLIM imaging technology to visualize protein associations in live cells.

The brain's connectome -- from branch to branch

Researchers have developed a method to reconstruct neural networks in detail, using computer programs KNOSSOS and RESCOP. The team successfully mapped over 100 neurons from the retina with high accuracy, reducing the time required compared to previous methods.

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GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Caltech researchers create the first artificial neural network out of DNA

Researchers at Caltech created an artificial neural network out of DNA, exhibiting brain-like behavior by recalling memories based on incomplete patterns. The DNA-based neural network consists of four artificial neurons made from 112 distinct DNA strands and demonstrated correct responses in a mind-reading game.

Cracking the code of the mind

Researchers create a chip that connects neurons with electronics, enabling them to study complex neural networks and their behavior. The device reveals patterns in bigger networks of neurons, showing hierarchical structures and suggesting new approaches for artificial intelligence and neurology.

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Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Early light refines the brain's circuitry for vision

Two new studies show that light exposure enhances the brain's ability to organize nerve endings from each eye, leading to improved sorting of visual signals. Researchers discovered that a specific type of light-sensitive cell plays a crucial role in this process.

Apple Watch Series 11 (GPS, 46mm)

Apple Watch Series 11 (GPS, 46mm) tracks health metrics and safety alerts during long observing sessions, fieldwork, and remote expeditions.

Paraplegic man stands, steps with assistance and moves his legs voluntarily

Researchers at the University of Louisville have achieved significant breakthroughs in treating paraplegia through epidural spinal cord stimulation and extensive locomotor training. The study's results, published in The Lancet, show that a paralyzed man can stand, step, and move his legs voluntarily with assistance.

'Computer synapse' analyzed at the nanoscale

Researchers have analyzed the physical and chemical properties of memristors using highly focused x-rays, providing a detailed insight into their behavior. This study is crucial for understanding how memristors work, which will lead to novel applications in semi-autonomous robots and complex electronic circuits.

MIT control theory research: How to control complex networks

A new computational model analyzes any type of complex network, revealing critical points for controlling the entire system. Researchers found sparse networks require more nodes to control, while dense networks need fewer. The algorithm offers potential applications in reprogramming adult cells and identifying new drug targets.

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Flipping a switch on neuron activity

Researchers at the University of California and Germany have developed light-sensing modules to attach to neuronal molecules, allowing for real-time study of complex cascades. This breakthrough enables selective activation of individual classes of molecules, paving the way for new treatments for vision impairments.

Trial and error: The brain learns from mistakes

Researchers have identified a protein that corrects errors in the brain's neuronal connections during development. Bone morphogenetic protein 4 (BMP4) helps eliminate incorrect connections, establishing proper specificity in the cerebellum and potentially contributing to neurological disorders like autism.

Beating the competition

A new connection can significantly enhance the size of a network, according to researchers from Max Planck Institute. By tracing link by link, scientists found that after a certain number of new links, a sudden growth spurt occurs, leading to a dramatic increase in network size.

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Carnegie Mellon researchers identify 'Facebook neurons'

Researchers used a transgenic mouse model to visualize the most active neurons in the neocortex, finding that they act like a small population of highly connected individuals on Facebook. This discovery could lead to a better understanding of the brain's center of higher learning and its role in learning.

'Timing is everything' in ensuring healthy brain development

Brain cells need to create links early on in their existence to ensure successful connections across the brain. This is demonstrated through computer analysis of nerve cell connectivity patterns in roundworms, showing that most neurons develop long-distance connections by being physically close together.

From the brain of a locust

Researchers at Tel Aviv University have made a groundbreaking discovery that mechanical stress is instrumental in several key phenomena in neuronal development. The team used insect cells, including those from the desert locust, to build an in vitro nervous system and observe how neurons form a network.

Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

Tea leaves identified using neural networks

A team of chemists used artificial neural networks to analyze tea leaves' mineral content and identify the type of tea. The technique achieved a high accuracy rate, allowing for clear differentiation between white, green, black, Oolong, and red tea varieties.

UTHealth neuroscientist wins prominent NIH Director's Pioneer Award

Valentin Dragoi, a UTHealth neuroscientist, has won the prestigious NIH Director's Pioneer Award to study how the brain processes information and develop new technologies to monitor neural activity in naturalistic environments. This award will support his high-impact approach to understanding major challenges in biomedical research.

AmScope B120C-5M Compound Microscope

AmScope B120C-5M Compound Microscope supports teaching labs and QA checks with LED illumination, mechanical stage, and included 5MP camera.

Blinking neurons give thoughts away

Researchers successfully used a specialized fluorescent protein to visualize electrical activity in living mice, allowing them to study brain function and behavior in real-time. The 'cameleon' protein enables measurement of action potentials without electrodes, providing insights into neural networks and brain circuitry.

The role of sleep in brain development

Research reveals that sleep triggers cellular changes that promote memory formation, involving the NMDAR molecule. The brain undergoes significant reorganization during sleep to strengthen neural connections.

How nerve cells grow

Researchers have discovered a molecular process that controls the growth of nerve cells, allowing them to form complex extensions for signal transmission. The study highlights the importance of Nedd4-1 enzyme in regulating cytoskeleton structure and ensuring normal dendrite growth.

Creality K1 Max 3D Printer

Creality K1 Max 3D Printer rapidly prototypes brackets, adapters, and fixtures for instruments and classroom demonstrations at large build volume.

Strictly ballroom analysis

Researchers developed a neural network system to classify music genres, such as cha-cha-cha, jive, and tango, with varying degrees of success. The approach combines the strengths of two existing methods and uses a neural network to analyze beat and tempo, outperforming other classification techniques.

Blur's noise and distortion reversed

Researchers develop modified recurrent Hopfield neural network to quickly process images, reducing distortion, noise and blurring. The approach shows significant improvement in image quality by 39-67% and takes half the time of other methods.

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Imaging the hypnotized brain: Neural mechanisms of suggested paralysis

Research reveals hypnosis induces disconnection of motor commands from normal voluntary processes through executive control and self-image circuits. The study used fMRI to test neural effects of hypnotic paralysis on brain activity, finding enhanced activation of the precuneus region involved in memory and self-imaging.

Neurodegenerative diseases target healthy brain's intrinsic networks

Studies using brain imaging have identified distinct regional vulnerabilities within five intrinsic networks, suggesting a class-wide phenomenon of network degeneration. These findings support the hypothesis that spatial patterning of disease relates to structural or physiological aspects of neural network biology.

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Activation of the prefrontal cortex improves working memory

A study by IDIBAPS reveals that prefrontal cortex activation improves working memory by reinforcing parietal cortex activity, enhancing short-term visual information retention. This innovative view opens up new research avenues, particularly for understanding and treating diseases affecting working memory.

Computer simulations explain the limitations of working memory

The study reveals a mechanism in the brain's neuronal network that restricts working memory capacity to two to seven items, with frontal lobes regulating parietal lobe memory capacity. The 'model brain' computations were confirmed using fMRI experiments and suggest improved working memory through increased frontal lobe activation.