A new method developed by Purdue University's chemical engineers uses artificial intelligence to simultaneously test thousands of formulations, drastically speeding up the discovery process. The technique has the potential to significantly improve catalyst performance and result in substantial economic benefits.
Hebrew University and Ben-Gurion researchers found that stress causes a shift in gene products, resulting in an oversensitive electrical response in neurons. This could lead to improved treatment options for patients taking drugs that affect the nervous system.
SourceThe Hebrew University of Jerusalem·JournalScience·DateJan 17, 2002
Research by Harriet Hanlon explores how neural networks process language skills in boys and girls, finding differences in brain connectivity that impact reading abilities. The study suggests a balanced approach to language instruction can benefit both sexes.
Scientists aim to develop novel optical imaging technique to capture detailed images of large numbers of brain neurons. The project, led by Leif H. Finkel, brings together experts in bioengineering, neuroscience and physics to overcome limitations of current techniques, enabling study of neural network activity changes with learning.
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Researchers have gained a close look at synapses and dendritic spines governing brain function using high resolution imaging technique two-photon microscopy. They discovered that single calcium channels in these structures are responsible for triggering changes in neurons, encoding memories and processing information.
SourceCold Spring Harbor Laboratory·JournalNature·DateNov 28, 2000
A new model for neuronal cell death in inherited neurodegenerative diseases proposes that mutant genes increase the risk of sudden programmed cell death. Researchers aim to target factors leading to increased neuronal death risk by identifying critical reactions, which could lead to effective treatments.
Scientists at Max Planck Institute discover novel potassium current activated by calcium, shaping neural signal frequency. SK channels play a crucial role in neuronal adaptation, influencing brain function and learning. The study resolves a long-standing controversy between electrophysiology and apamin-binding studies.
SourceMax-Planck-Gesellschaft·JournalMolecular and Cellular Neuroscience·DateMay 21, 2000
Researchers found a 28% decline in brain network density with normal aging in monkeys, which was reversed by transplanting genetically programmed nerve growth factor-producing cells. This approach may be useful for treating Alzheimer's disease, with clinical trials underway.
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Researchers discovered that injured spinal neurons establish gap junctions to communicate with each other, but not with healthy neighboring cells. This finding suggests a new approach to re-establishing connectivity between neurons and muscle after peripheral nerve damage or spinal cord injury.
SourceUniversity of Pennsylvania School of Medicine·DateJan 12, 2000
Researchers have mapped the functional organization of the hippocampus, a critical area for short-term memory, using microelectrodes to record electrical impulses from individual neurons. The study shows that different portions of the hippocampus are active at different times depending on the type of memory function required.
SourceAtrium Health Wake Forest Baptist·JournalNature·DateDec 8, 1999
Researchers at Brown University discovered that certain inhibitory neurons in the cerebral cortex use electrical synaptic connections to coordinate their activity. This allows for highly synchronized firing and synchrony similar to blinking lights.
UCSD researchers successfully integrated electronic neuron within a group of biological neurons, demonstrating the potential for restoring brain function. The key finding was the simplification of mathematical algorithms, allowing for a radical reduction in variables to control a neuron's overall function.
Researchers at USC created a machine system that recognizes spoken words better than humans, with the ability to distinguish words in vast amounts of random noise. The novel neural network architecture mimics the biological system's temporal dimension, allowing it to process information structured in time.
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A new research method reveals that information can be stored on the surface of neurons with very high spatial density, similar to a CD-ROM. The method allows precise control over neurotransmitter release and discovered that modifications are highly restricted, enabling single synapses to store information separately.
SourceMax-Planck-Gesellschaft·JournalScience·DateSep 30, 1999
Researchers at Boston University developed a biologically inspired model to improve the fidelity of electronic devices by mimicking the noise-shaping abilities of neuronal networks. The system can effectively filter out unwanted information and identify desired signals over a wider bandwidth.
SourceBoston University·JournalProceedings of the National Academy of Sciences·DateSep 1, 1999
Researchers have created living nerve cell colonies on silicon chips that can be used to study the brain's functions and potentially develop new prosthetic devices. The colonies, grown from rat hippocampal neurons, can live for extended periods and communicate with each other through a matrix of electrodes.
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The Cellular Automata Machine (CAM) brain will be built under contract by Genobyte, a company in Boulder, Colorado. It will contain nearly 40 million artificial neurons, compared to the few hundred neurons used in most other specialists in artificial intelligence.
SourceNew Scientist·JournalThe New Scientist·DateJan 6, 1999
Researchers at Duke University have discovered that nerve growth factors can oppose each other in the brain, shaping neural networks in response to experience and learning. This finding has significant implications for the development of therapies for neurodegenerative disorders such as ALS and Alzheimer's disease.