Articles tagged with Neurons
Neurons can modulate nerve impulses by releasing two neurotransmitters that target the same receptor, accelerating inhibition and enhancing temporal resolution of inhibition. This finding may represent a new way the brain precisely controls nerve impulses in its circuitry.
Researchers suggest that minocycline can limit Japanese Encephalitis (JE) death by reducing neuronal death, microgliosis, and viral titre. The study found that treatment with minocycline provides complete protection against experimental JE, improving behavioral outcome as well.
Researchers at Stanford University School of Medicine used human embryonic stem cells to generate neural cells that helped repair damage in the brains of rats and improved their physical abilities. The study showed promising results, with the transplanted cells forming only three families of neural cells and not forming tumors.
New research reveals VEGF-B's protective effects on nerve cells without inducing angiogenesis, providing new hope for treating neurodegenerative diseases. VEGF-B treatment has shown to inhibit brain cell death in mouse models of stroke and ocular neurodegenerative disorders.
A study by Northwestern University's Feinberg School of Medicine found that chronic pain disrupts the equilibrium of the brain's regions, leading to permanent damage. This constant firing of neurons can alter connections and even cause death.
A study found that eating apples, bananas, and oranges can protect against neurodegenerative diseases like Alzheimer's. The fruits' phenolic phytochemicals prevented neurotoxicity in neuron cells.
A recent study by Weill Cornell Medical College reveals that the brain contains its own store of tissue plasminogen activator (tPA), a powerful enzyme that boosts blood flow to brain cells via nitric oxide synthase. This finding has significant implications for understanding stroke and Alzheimer's disease, and may lead to new treatments.
Scientists at Cold Spring Harbor Laboratory identify a new neural stem cell type, the rosette neuron stem cell (R-NSC), capable of differentiating into region-specific neuronal cell types. The R-NSC has expanded differentiation potential compared to previously identified neural stem cells.
Researchers discover that individual brains are adapted to their unique auditory environment and can learn to localize sounds. The study may lead to more sophisticated hearing aids and speech recognition systems.
UCI researchers have found a novel method to sort stem cells based on their electric charges, which could expedite therapies for conditions like Alzheimer's and Parkinson's diseases. The technique uses electrodes on a tiny glass slide and has the potential to be more cost-effective and quicker than current methods.
A Northwestern University study found that overexcited neurons can cause protein damage in muscle cells due to neurotransmitter imbalance. This imbalance can lead to various diseases, including neurodegenerative disorders and cancer.
Researchers found that boosting autophagy in fruit flies prevented the age-dependent accumulation of cellular damage in neurons and promoted longevity. Boosting autophagy facilitated the removal of damaged molecules that accumulate during cellular aging, which is critical for neurons to stay healthy and functioning.
Researchers at Stanford University School of Medicine have discovered that the immune system plays a role in sculpting away unwanted synapses in the developing brain. The finding could lead to new treatments for neurodegenerative diseases such as glaucoma, Alzheimer's disease, and multiple sclerosis.
Research suggests that neurons in the frontal lobe encode economic value in a 'menu invariant' way, enabling transitive preferences. This finding provides a key insight into the neural circuits underlying decision-making and may shed light on choice deficits associated with frontal lobe damage.
Researchers have discovered a novel method to produce dopamine cells for Parkinson's disease treatment by cultivating ventral midbrain neural stem cells with Wnt5a. This approach yielded substantial recovery in mice with PD-like disease, without tumor development.
Two transporters, SMCT1 and SMCT2, can circumvent the blood-retinal barrier to deliver lactate and ketone bodies to a healthy eye, potentially preventing neuronal cell damage. Understanding these transporters' activity may enable early diagnosis of diabetic retinopathy and natural delivery mechanisms for drugs.
A recent study by MIT scientists suggests that adult stem cells produced in the brain can only make limited connections, making it challenging to use them for replacement therapy. The research calls into question the potential of using adult stem cells to repair damaged brain tissue and replace lost neurons.
Researchers found that acetylcholine enhances visual processing by selectively enhancing information in the brain's visual cortex. This enhancement allows neurons to detect and signal stimuli below detection threshold, a process similar to how attention strengthens signals.
Neuroscientists are developing software that may turn thoughts into speech for patients like Eric Ramsey, who was left 'locked-in' after a car accident. By analyzing signals from his brain activity, the team has identified distinct patterns associated with vowel sounds, allowing them to correctly identify around 80% of the time.
Researchers found that the NF1 gene regulates the development of astrocytes and neurons by controlling two signaling pathways. This discovery may lead to separate treatments for the condition's two major symptoms: brain cancers and learning disabilities.
Scientists found that Roaccutane increases production of proteins reducing serotonin availability, potentially leading to depression-related behavior. Low serotonin levels are linked to aggression and clinical depression.
A new imaging technique has enabled scientists to measure mouse satiety and hunger levels in the brain, offering a more objective understanding of why people become obese. The study used magnetic resonance imaging to observe neuronal activity in the hypothalamus area, revealing that certain neurons 'light up' when mice are hungry or full.
Researchers used C. elegans to study sex differences in brain function, finding that hermaphrodites prefer buttery smells while males prefer fresh vegetables. The team's genetic modification revealed that even few neurons can influence behavior, challenging the idea that all sex differences result from neuron-specific differences.
Researchers at Harvard University have developed a new technique called Brainbow that allows for the imaging of neurons in a wide range of colors, enabling scientists to better map the complex wiring diagram of the brain and nervous system. This breakthrough has significant implications for understanding brain disorders and development.
Researchers at the University of Illinois found a common nervous system receptor that inhibits its binding protein, leading to abnormal neuron growth and development. This unusual mechanism directs the formation of tens of thousands of neurons vital for odor detection.
Researchers found that excessive glucose chains induce neuronal death and cause Lafora disease by disrupting glycogen levels. This discovery may lead to new treatment strategies for other neurodegenerative diseases.
Researchers detected viral genetic material in the placenta of a pregnant woman who died from bird flu. The study found that H5N1 virus can infect organs other than the lungs, including the brain, liver, and intestinal cells, in infected adults and fetuses.
A study on Gambel's white-crowned sparrows reveals that the brain regions controlling singing behavior shrink rapidly after testosterone withdrawal, leading to neuron loss and apoptosis. This natural phenomenon may hold potential medical implications for understanding age-related degenerative diseases such as Parkinson's and dementia.
Researchers at Baylor College of Medicine discovered that approximately 10% of subplate neurons survive into adulthood and maintain functional connections. These cells generate electrical signals and receive inputs from neighboring neurons, undergoing plasticity to adapt to experience and activity.
McMaster researchers have made an important finding about Fragile X Syndrome (FXS), a sex-linked genetic disorder that affects cognitive function and learning. The study discovered that glial cells in the brain also produce the fragile X mental retardation protein (FMRP), contributing to abnormal neuronal structures seen in FXS patients.
Scientists discovered that gap junctions play a crucial role in neuronal migration, and their adhesion function may also contribute to cancer spread. The discovery highlights the potential for gap junctions as a therapeutic target in brain tumors.
Researchers at Cornell University found that ion channels in membrane-bound vesicles do not carry charged neurotransmitters out of the cell. Instead, positive sodium ions from the outside compensate for the charge, a process known as electrodiffusion.
Scientists have discovered that glucose-sensing neurons play an important role in regulating blood glucose levels in mice with obesity-induced Type 2 diabetes. The study found that defects in these neurons contribute to the disease's progression and may be targeted by novel therapies.
Fruit flies have been found to detect and be attracted to the taste of carbon dioxide dissolved in water, which may aid in scouting for nutritious food. This discovery suggests that humans may also be able to taste carbon dioxide, making their sense of taste more complex.
Researchers discovered a link between impaired brain glucose sensing and type 2 diabetes development in mice. A high-fat diet may contribute to this impairment by disrupting ATP production, leading to reduced glucose-sensing ability.
University of Maryland researchers found a unique olfactory system in mice that can detect hormones involved in regulating water and salt balance. This discovery may lead to new understanding of social information transmission between individuals.
Researchers at University of Wisconsin-Madison discovered that Viagra significantly boosts the release of key reproductive hormone, offering potential new insights into male fertility and sexual health.
Researchers at Carnegie Mellon have modeled the molecular changes that occur when glutamate docks with a receptor on a neuron, enabling computer simulation of binding-site closure and opening. This breakthrough could lead to the development of drug therapies for disorders such as epilepsy and Alzheimer’s disease.
A University of Oregon research team has found that barn owls' exceptional spatial hearing abilities can help pinpoint problems in the human brain, including those related to hearing and behavior. The study used infrared monitoring to track changes in pupil dilation responses influenced by sound sources around an owl.
Researchers have identified Müller glial cells with stem cell properties that can regenerate the retina and restore vision in zebrafish. The team hopes to develop this approach for human use, potentially using a person's own cells to stimulate growth and repair.
Researchers used the Stroop task to test grapheme-color synesthetes, finding that opponent incongruent colors made it difficult for them to respond quickly. However, memories of objects associated with those same colors were not affected by color change. These findings suggest that synesthetic colors are perceived in a realistic way.
In a study published in PLOS Biology, researchers discovered parietal neurons that respond with increasing activity as the number of items in a display is varied, suggesting an accumulator neuron role. This finding supports computer models separating summing and numerical identification processes.
A University of Southern California study reveals that sugar molecules attached to the surface of the receptor act as a hinge, opening a gate in the cell membrane and transmitting news of nicotine's arrival. The research also identifies a water molecule deep in the receptor's core, which may enable the receptor to alter its shape.
Researchers have identified a specific amino acid in the potassium channel protein that blocks anaesthetic activation, paving the way for targeted anaesthetics with fewer side effects. This discovery could lead to improved understanding of how anaesthetics work and the development of new, more specific alternatives.
A recent study published in Neuron found that the brain's neural activity changes when searching for specific objects, regardless of their location. The researchers used fMRI to measure brain activity and discovered patterns of activity that were not previously understood.
Researchers identified the lateral occipital complex as a region affected by both working memory load and pain, but found that pain influences visual processing through the rostral anterior cingulate cortex. This modulation affects accuracy in recognizing images.
Researchers at the University of California, San Diego discovered that fibrinogen inhibits neural cell growth in spinal cord injuries, leading to paralysis. The study found that fibrinogen's binding to beta 3 integrin receptor and epidermal growth factor receptor prevents axonal growth, which is necessary for regeneration.
Dr. Douglas Black and colleagues reveal that a switch in PTB expression induces changes in alternative splicing patterns during neuronal development, adding a new layer of genetic regulation. This reprogramming enables the creation of unique genetic code in post-mitotic neurons.
A specific resonance pattern in the brain's auditory processing region is crucial for distinguishing speech, according to researchers. The inherent rhythm of neural activity in the theta band reacts to spoken sentences by changing its phase and samples segments about a syllable's length.
Researchers found that female mice with given birth had better auditory neurons at detecting and discriminating pup calls. The study suggests the brain improves information processing for specific communicative functions.
Scientists have discovered a mechanism that can organize the activity of cells involved in short-term recall known as working memory. The study found that inhibitory neurons play a key role in coordinating this process, which could lead to improved treatment options for individuals with schizophrenia.
Researchers at Stanford University School of Medicine have successfully tracked human neural stem cells transplanted into the brains of rats, which migrated towards damaged areas and matured into functional neurons. The study used iron particles to track the cells in real-time, paving the way for potential human clinical trials.
Scientists at Rockefeller University have identified a key player in the development of left-right asymmetry in the roundworm Caenorhabditis elegans. A gene involved in gap junctions establishes communication between neurons on opposite sides, allowing them to coordinate their activity and create permanent differences. This discovery p...
Scientists have successfully implanted dopamine generators in brain cells, leading to improved symptoms in Parkinson's disease in non-human primates. The treatment involves injecting fragments of the carotid body into the striate area of the brain, which boosts the production of dopaminergic cells and increases dopamine release.
Researchers have found a way to induce autophagy, a process where cells recycle waste material, including misfolded proteins. By administering small molecules that enhance this process, they aim to stall the onset of Huntington's-like symptoms in humans.
AIDS researcher Dr. Edward Johnson has received a $1.8M NIH grant to study the molecular mechanics of progressive multifocal leukoencephalopathy (PML), a brain disease that kills four percent of AIDS patients worldwide. The research aims to understand how the JC virus causes PML, which can occur even in patients with well-managed AIDS.
Hopkins researchers discovered a backup supply of stem cells that can repair severe damage to the nerves responsible for our sense of smell. These stem cells, called HBCs, grow from a population of cells not previously known for repair abilities and generate other active nasal stem cells.
A UCLA/University of Toronto team has discovered a protein called CREB controls neuron participation in memory formation, suggesting a new approach for preserving memory in people with Alzheimer's or brain injury. The study found that high levels of CREB lead to more likely storage of memories.
Researchers pinpointed brain regions critical to piecing together a continuous view of the world. By using an illusion known as boundary extension, they found two brain areas involved in extrapolating scenes and integrating discrete samples of surrounding space.
Researchers used physiological data to show how a theoretical model explains behavior in children with attention deficit hyperactivity disorder (ADHD). The study found that the 'go' and 'stop' processes are intricately linked, resolving a long-standing paradox.