Articles tagged with Neurons
Neuroscientists are developing software that may turn thoughts into speech for patients like Eric Ramsey, who was left 'locked-in' after a car accident. By analyzing signals from his brain activity, the team has identified distinct patterns associated with vowel sounds, allowing them to correctly identify around 80% of the time.
Researchers found that the NF1 gene regulates the development of astrocytes and neurons by controlling two signaling pathways. This discovery may lead to separate treatments for the condition's two major symptoms: brain cancers and learning disabilities.
Scientists found that Roaccutane increases production of proteins reducing serotonin availability, potentially leading to depression-related behavior. Low serotonin levels are linked to aggression and clinical depression.
A new imaging technique has enabled scientists to measure mouse satiety and hunger levels in the brain, offering a more objective understanding of why people become obese. The study used magnetic resonance imaging to observe neuronal activity in the hypothalamus area, revealing that certain neurons 'light up' when mice are hungry or full.
Researchers used C. elegans to study sex differences in brain function, finding that hermaphrodites prefer buttery smells while males prefer fresh vegetables. The team's genetic modification revealed that even few neurons can influence behavior, challenging the idea that all sex differences result from neuron-specific differences.
Researchers at Harvard University have developed a new technique called Brainbow that allows for the imaging of neurons in a wide range of colors, enabling scientists to better map the complex wiring diagram of the brain and nervous system. This breakthrough has significant implications for understanding brain disorders and development.
Researchers at the University of Illinois found a common nervous system receptor that inhibits its binding protein, leading to abnormal neuron growth and development. This unusual mechanism directs the formation of tens of thousands of neurons vital for odor detection.
Researchers found that excessive glucose chains induce neuronal death and cause Lafora disease by disrupting glycogen levels. This discovery may lead to new treatment strategies for other neurodegenerative diseases.
Researchers detected viral genetic material in the placenta of a pregnant woman who died from bird flu. The study found that H5N1 virus can infect organs other than the lungs, including the brain, liver, and intestinal cells, in infected adults and fetuses.
A study on Gambel's white-crowned sparrows reveals that the brain regions controlling singing behavior shrink rapidly after testosterone withdrawal, leading to neuron loss and apoptosis. This natural phenomenon may hold potential medical implications for understanding age-related degenerative diseases such as Parkinson's and dementia.
Researchers at Baylor College of Medicine discovered that approximately 10% of subplate neurons survive into adulthood and maintain functional connections. These cells generate electrical signals and receive inputs from neighboring neurons, undergoing plasticity to adapt to experience and activity.
McMaster researchers have made an important finding about Fragile X Syndrome (FXS), a sex-linked genetic disorder that affects cognitive function and learning. The study discovered that glial cells in the brain also produce the fragile X mental retardation protein (FMRP), contributing to abnormal neuronal structures seen in FXS patients.
Scientists discovered that gap junctions play a crucial role in neuronal migration, and their adhesion function may also contribute to cancer spread. The discovery highlights the potential for gap junctions as a therapeutic target in brain tumors.
Researchers at Cornell University found that ion channels in membrane-bound vesicles do not carry charged neurotransmitters out of the cell. Instead, positive sodium ions from the outside compensate for the charge, a process known as electrodiffusion.
Scientists have discovered that glucose-sensing neurons play an important role in regulating blood glucose levels in mice with obesity-induced Type 2 diabetes. The study found that defects in these neurons contribute to the disease's progression and may be targeted by novel therapies.
Fruit flies have been found to detect and be attracted to the taste of carbon dioxide dissolved in water, which may aid in scouting for nutritious food. This discovery suggests that humans may also be able to taste carbon dioxide, making their sense of taste more complex.
Researchers discovered a link between impaired brain glucose sensing and type 2 diabetes development in mice. A high-fat diet may contribute to this impairment by disrupting ATP production, leading to reduced glucose-sensing ability.
University of Maryland researchers found a unique olfactory system in mice that can detect hormones involved in regulating water and salt balance. This discovery may lead to new understanding of social information transmission between individuals.
Researchers at University of Wisconsin-Madison discovered that Viagra significantly boosts the release of key reproductive hormone, offering potential new insights into male fertility and sexual health.
Researchers at Carnegie Mellon have modeled the molecular changes that occur when glutamate docks with a receptor on a neuron, enabling computer simulation of binding-site closure and opening. This breakthrough could lead to the development of drug therapies for disorders such as epilepsy and Alzheimer’s disease.
A University of Oregon research team has found that barn owls' exceptional spatial hearing abilities can help pinpoint problems in the human brain, including those related to hearing and behavior. The study used infrared monitoring to track changes in pupil dilation responses influenced by sound sources around an owl.
Researchers have identified Müller glial cells with stem cell properties that can regenerate the retina and restore vision in zebrafish. The team hopes to develop this approach for human use, potentially using a person's own cells to stimulate growth and repair.
Researchers used the Stroop task to test grapheme-color synesthetes, finding that opponent incongruent colors made it difficult for them to respond quickly. However, memories of objects associated with those same colors were not affected by color change. These findings suggest that synesthetic colors are perceived in a realistic way.
In a study published in PLOS Biology, researchers discovered parietal neurons that respond with increasing activity as the number of items in a display is varied, suggesting an accumulator neuron role. This finding supports computer models separating summing and numerical identification processes.
A University of Southern California study reveals that sugar molecules attached to the surface of the receptor act as a hinge, opening a gate in the cell membrane and transmitting news of nicotine's arrival. The research also identifies a water molecule deep in the receptor's core, which may enable the receptor to alter its shape.
Researchers have identified a specific amino acid in the potassium channel protein that blocks anaesthetic activation, paving the way for targeted anaesthetics with fewer side effects. This discovery could lead to improved understanding of how anaesthetics work and the development of new, more specific alternatives.
A recent study published in Neuron found that the brain's neural activity changes when searching for specific objects, regardless of their location. The researchers used fMRI to measure brain activity and discovered patterns of activity that were not previously understood.
Researchers identified the lateral occipital complex as a region affected by both working memory load and pain, but found that pain influences visual processing through the rostral anterior cingulate cortex. This modulation affects accuracy in recognizing images.
Researchers at the University of California, San Diego discovered that fibrinogen inhibits neural cell growth in spinal cord injuries, leading to paralysis. The study found that fibrinogen's binding to beta 3 integrin receptor and epidermal growth factor receptor prevents axonal growth, which is necessary for regeneration.
Dr. Douglas Black and colleagues reveal that a switch in PTB expression induces changes in alternative splicing patterns during neuronal development, adding a new layer of genetic regulation. This reprogramming enables the creation of unique genetic code in post-mitotic neurons.
A specific resonance pattern in the brain's auditory processing region is crucial for distinguishing speech, according to researchers. The inherent rhythm of neural activity in the theta band reacts to spoken sentences by changing its phase and samples segments about a syllable's length.
Researchers found that female mice with given birth had better auditory neurons at detecting and discriminating pup calls. The study suggests the brain improves information processing for specific communicative functions.
Scientists have discovered a mechanism that can organize the activity of cells involved in short-term recall known as working memory. The study found that inhibitory neurons play a key role in coordinating this process, which could lead to improved treatment options for individuals with schizophrenia.
Researchers at Stanford University School of Medicine have successfully tracked human neural stem cells transplanted into the brains of rats, which migrated towards damaged areas and matured into functional neurons. The study used iron particles to track the cells in real-time, paving the way for potential human clinical trials.
Scientists at Rockefeller University have identified a key player in the development of left-right asymmetry in the roundworm Caenorhabditis elegans. A gene involved in gap junctions establishes communication between neurons on opposite sides, allowing them to coordinate their activity and create permanent differences. This discovery p...
Scientists have successfully implanted dopamine generators in brain cells, leading to improved symptoms in Parkinson's disease in non-human primates. The treatment involves injecting fragments of the carotid body into the striate area of the brain, which boosts the production of dopaminergic cells and increases dopamine release.
Researchers have found a way to induce autophagy, a process where cells recycle waste material, including misfolded proteins. By administering small molecules that enhance this process, they aim to stall the onset of Huntington's-like symptoms in humans.
AIDS researcher Dr. Edward Johnson has received a $1.8M NIH grant to study the molecular mechanics of progressive multifocal leukoencephalopathy (PML), a brain disease that kills four percent of AIDS patients worldwide. The research aims to understand how the JC virus causes PML, which can occur even in patients with well-managed AIDS.
Hopkins researchers discovered a backup supply of stem cells that can repair severe damage to the nerves responsible for our sense of smell. These stem cells, called HBCs, grow from a population of cells not previously known for repair abilities and generate other active nasal stem cells.
A UCLA/University of Toronto team has discovered a protein called CREB controls neuron participation in memory formation, suggesting a new approach for preserving memory in people with Alzheimer's or brain injury. The study found that high levels of CREB lead to more likely storage of memories.
Researchers pinpointed brain regions critical to piecing together a continuous view of the world. By using an illusion known as boundary extension, they found two brain areas involved in extrapolating scenes and integrating discrete samples of surrounding space.
Researchers used physiological data to show how a theoretical model explains behavior in children with attention deficit hyperactivity disorder (ADHD). The study found that the 'go' and 'stop' processes are intricately linked, resolving a long-standing paradox.
Researchers discovered hundreds of genes that bind to CREB and zif268, a crucial step towards understanding neural plasticity. The study's online database provides valuable insights into the molecular mechanisms behind learning and memory.
Researchers found that stem cells can induce a protective effect in brain tissue damaged by stroke, reducing ischemic injury. The study reveals that microglia cells also play a protective role in this reaction.
A Brandeis University study shows that the circadian neuronal network in fruit flies functions as a dynamic system that enables insects to adjust their behavior according to seasonal changes. The researchers discovered that two groups of neurons, morning cells and evening cells, alternate as master clocks depending on day length and se...
Neurobiologists found that richer individuals are slower to learn associating a stimulus with financial reward, leading to slower brain responses in reward areas. The study also measured marginal utility of money, finding greater wealth reduces the likelihood of picking up coins on the street.
A recent study found that reducing calorie intake later in life can induce health and longevity benefits similar to lifelong calorie reduction. The researchers discovered that certain drugs mimic this effect, which may lead to the development of new
Scientists at MIT have developed a way to reversibly silence brain cells using pulses of yellow light, potentially leading to the development of optical brain prosthetics. The method could enable specific treatments with few or no side effects, offering new hope for neurological and psychiatric diseases.
A leading theory of neural coding has been challenged by a Weizmann Institute research team, suggesting that brain function may be more dependent on chance than previously thought. The study found no evidence to support the idea that specific patterns of activity in neurons encode cognitive information.
Researchers have discovered that neural progenitor cells derived from human fetal stem cells can protect the vision of animals with degenerative eye disease. The new findings suggest novel ways to preserve vision in humans with no effective treatments.
A new study identifies a key molecular pathway in neurons that contributes to brain cell degeneration, a process linked to conditions such as Alzheimer's disease and epilepsy. The Rho protein plays a crucial role in this destruction of neurons, and blocking its activity can prevent cell death.
Neurobiologists have found that DNA methylation is necessary for forming memories and regulates the activity of genes involved in memory formation. The study suggests that epigenetic regulation has a significant impact on behavioral changes brought about by environmental stimuli.
Functional connectivity MRI studies revealed that lower brain connectivity regions correlate with impaired visual field perception in neglected stroke patients. The study provides new insights into the neurological details of spatial neglect, highlighting the value of MRI in studying behavioral symptoms.
Researchers found two basic categories of cells: those that stay the same size but have drastically different energy needs based on mammal size, or cells that grow larger in larger mammals. This discovery sheds light on how organism size affects cell life span and function.
Researchers found that obese mice's brains don't detect critical fat hormone levels, but the rest of the metabolic pathway remains responsive. SOCS-3 may be responsible for this loss of sensitivity to leptin, a hormone regulating energy balance.
Researchers discovered that cortical inhibitory cells suppress communication by receiving more stimulation from the thalamus and reacting strongly due to faster response time. This finding helps explain early stages of brain processing, memory, language, cognition, and sheds light on epilepsy causes.
Researchers discover that enhancing proteasome function can recover UPS function and improve cell viability in HD model and patient cells. This breakthrough suggests a potential therapeutic approach to address the underlying protein misfolding disorder of HD.
Researchers create a super-thin membrane, 50 atoms thick, that can sort individual molecules with high efficiency. This innovation has the potential to revolutionize dialysis, fuel cells, and neuro-stem cell cultivation.
Researchers develop a fluorescent marker to distinguish between mitochondria in neurons and glial cells, providing insights into neurodegenerative diseases. The study sheds light on the role of mitochondrial dysfunction in aging and neurological disorders.
Scientists have developed a potential neuroprotective treatment using a decoy peptide that tricks the toxic enzyme calpain, preventing over-excited receptors in the brain from causing cell death. The technique may lead to new drugs for stroke and Alzheimer's patients.