Articles tagged with Bones
Researchers from Chinese Academy of Sciences develop new strontium-substituted bioactive glass bone cement, optimizing strontium concentration to improve bone formation and implant contact. They find optimal osteogenic characteristics with 6 mol% SrO addition, supporting better peri-implant bone regeneration.
Researchers analyzed ancient potsherds to find clues about the diet and subsistence practices of ancient East African pastoralists. They discovered that ruminant meat, bones, and marrow were a staple, while milk residues were present at low frequencies.
A 29-million-year-old coquí frog fossil discovered in Puerto Rico has been identified as the oldest record of frogs in the Caribbean. The ancient species displaces an amber frog fossil previously thought to be the oldest, shedding new light on the origins of Caribbean wildlife.
The journal has announced its most frequently cited papers from 2018-19, which will be freely accessible. These papers focus on various aspects of musculoskeletal research, including bone metabolism, osteoimmunology, and gut-muscle axis.
Researchers have identified a new gene, SMAD3, associated with melorheostosis, a rare condition causing excessive bone tissue growth. The study provides a breakthrough in understanding the disease's causes and may lead to the development of treatments.
A new study found that artificial intelligence (AI) can accurately identify patients at risk of osteoporosis and fractures by analyzing electronic radiology reports, outperforming traditional manual methods. The AI tool, XRAIT, detected a significant number of major fractures, improving patient outcomes and reducing the burden of illness.
A new study analyzes human bones from medieval cemeteries to shed light on ancient copper cookware. Researchers found that people consumed tiny portions of copper daily, with cities like Ribe using copper pots for 1000 years.
Researchers discovered that bones change shape in response to forces, curving to prevent fractures. The study used computational methods to monitor shape changes over an extended period, finding that the curving process needs to be highly targeted and can lead to a built-in warning mechanism.
A nationwide study found that racial/ethnic minorities and individuals with lower incomes are less likely to receive office-based care for musculoskeletal conditions, while those with public insurance status are more likely to use emergency department care. This disparity contributes significantly to healthcare expenditures.
Researchers at UConn School of Dental Medicine have discovered a population of stem cells residing along vascular channels in bone that can generate new bone-forming cells. These perivascular cells may regulate bone formation and participate in bone mass maintenance.
Researchers from the University of Bonn analyzed a 15-20 million year old Anolis lizard forefoot preserved in Dominican Republic amber. Despite initial appearance, the bone showed significant chemical transformation and decomposition.
Researchers at the University of Pennsylvania have developed an affordable oral therapy to help broken bones heal faster in people with diabetes. The therapy, grown in plants, uses a protein called insulin-like growth factor-1 (IGF-1) to stimulate bone-building cells and promote bone regeneration.
Research finds high levels of selenium in California's Sacramento-San Joaquin Delta fish, causing spinal deformities and affecting their ear bones. The study provides insights into how the fish encounter selenium, shedding light on potential management strategies.
A team of researchers combined genealogical information with genetic data from modern Quebecers to access the genetic profile of Quebec's historical population. The study successfully identified approximately 1.7 million individuals, but limitations in genetic coverage hindered full identification, leaving around 88% of men married bef...
Scientists at DESY used an advanced X-ray combination technique to trace nanocarriers for tuberculosis drugs within cells with high precision. The method also revealed the calcium content in human bone, benefiting osteoporosis research.
Researchers discover that mature bone marrow stromal cells can transform into regenerative cells after an injury, providing an alternative source for bone healing. This breakthrough suggests that these cells could be generated through transformation of readily available mature stromal cells.
Scientists use molecular motors to manipulate protein structure, directing stem cells to differentiate into bone cells. The movement of motor molecules induces subtle structural changes, affecting cell attachment and behavior, ultimately leading to altered cell fate.
A specific gut bacterium, segmented filamentous bacteria (SFB), was found to impair normal skeletal growth and maturation in post-pubertal mice. This is achieved through a Gut-Liver-Bone Axis, where SFB elevates immune responses leading to increased osteoclast activity and decreased osteoblast activity.
A UCLA-led study used machine learning to analyze before-and-after photos of 100 female patients who underwent rhinoplasty, finding that the procedure can make women appear up to 3 years younger. The study estimated a person's age by cropping and extracting features from photographs.
Scientists investigate three 67 million year old oviraptorid egg fossils, determining that the embryos were at different developmental stages and likely hatched at different times. The findings suggest a unique nesting biology similar to modern birds, challenging previous assumptions about oviraptorids.
A 700,000-year-old fossil bone found in Japan indicates that a close relative of the modern dovekie was once thriving in the Pacific Ocean. The discovery suggests that dovekies were more abundant in Japan and the Pacific than previously thought.
Researchers have developed a new method to transform stem cells into bone cells using an artificial muscle sheet with shape-memory function. This technology has potential applications in treating complex bone fractures by culturing stem cells on the sheet and adapting them to directly strengthen bones.
A randomized study found that MIV-711 significantly reduced bone and cartilage progression in knee osteoarthritis patients. However, the treatment had no beneficial effects on osteoarthritic knee pain.
A study revealed oxytocin's role in promoting bone synthesis while curbing bone loss during pregnancy and lactation. Oxytocin administration also reduced total body fat in mice, suggesting potential as a drug target for these conditions.
After just two weeks of reduced physical activity, older adults experience significant losses in muscle mass and strength, as well as gains in body fat percentage. This can lead to a reduction in cardiorespiratory fitness and mitochondrial function, which are critical for maintaining healthy muscles and metabolic health.
Researchers from the University of Bonn used strontium isotope analysis to determine the origins of victims in a 1,400-year-old Maya mass grave. The study found that most victims grew up at least 95 miles from Uxul, with some showing signs of high social status.
Researchers at Baylor College of Medicine have identified a new mechanism that contributes to adult bone maintenance and repair. Periosteal stem cells, previously poorly understood, play a major role in bone healing and respond to mechanical injury and inflammatory molecules, offering potential therapeutic applications for conditions l...
New fossil species Origolestes lii sheds light on transitional gap in mammalian ear evolution. The discovery provides a crucial reference point for understanding the decoupling of jaw and hearing systems, paving the way for improved hearing and chewing capabilities in future mammals.
Researchers discovered that mimicking human bone's trabeculae structure can create artificial materials lasting up to 100 times longer than current designs. By increasing the thickness of horizontal struts, they achieved significant durability enhancements in 3D-printed polymers.
Researchers established B6CaP, a prostate-derived tumor line that frequently metastasizes to bones and grows in an immunocompetent host, overcoming limitations of previous models. This model is useful for studying mechanisms of bone metastasis and tumor immune response.
Researchers have found that Svalbard reindeer populations have recovered enough to recolonize virtually all non-glaciated areas in the archipelago. The population now numbers around 22,000, a significant increase from pre-hunting levels. Protection implemented in the 1920s has enabled the animals to thrive and expand their habitats.
A University of Colorado Cancer Center study suggests two new approaches to treating bone metastases from prostate cancer: targeting different signaling pathways for lytic and blastic lesions. Both types of bone metastases show promise with anti-cancer immunotherapy, particularly those with high PD-L1 levels.
Researchers found that Majungasaurus grew new teeth roughly two to 13 times faster than other carnivorous dinosaurs, replacing them every couple of months. This rapid tooth growth may have been due to the need to gnaw on bones to ingest certain nutrients, requiring exceptionally strong teeth.
A study published in PLOS ONE found that the meat-eating dinosaur Majungasaurus grew new teeth rapidly, possibly due to gnawing on bones. This rapid tooth replacement rate puts Majungasaurus in the same league as sharks and big herbivorous dinosaurs.
A team of researchers used micro-CT imaging to study the composition and age of 22 ancient ivory manikins, found in the Duke University collection. The study revealed that most of the manikins were composed of true elephant ivory, while some contained alternative materials such as antler or whale bone.
Researchers at Cornell University have discovered a way to strengthen bone structure using computer software, potentially treating osteoporosis and creating lightweight materials for the aerospace industry. The team found that horizontal rod-like struts play a crucial role in extending the fatigue life of bone.
Researchers developed nanoparticles that attach to microcracks, allowing for clear imaging using X-ray-based technique with hafnium particles. This breakthrough could enable doctors to detect serious problems like heart blockages more accurately.
A study using ancient bone protein analysis identified green turtles as a primary target for human consumption in Florida and the Caribbean thousands of years ago. The technique, collagen fingerprinting, allowed scientists to visualize distinct chemical signatures in collagen that are species-specific.
Researchers at UTSA are reexamining bone mineral density and proteoglycans to improve fracture risk assessments. Studies show that BMD captures only 50-60% of actual bone fragility fractures, highlighting the need for a more comprehensive approach.
A Rutgers study found that cycling-related facial and head injuries have remained steady despite an increase in bicyclists on the road. However, there was a significant rise in serious injuries among older adults, particularly those aged 55-64, with over 86,000 hospitalizations from 2008 to 2017.
Archaeologists have analyzed King Apries I's palace fragments and found two unknown pigments: lead-antimonate yellow and lead-tin yellow. These naturally occurring mineral pigments were used in European paintings from the Middle Ages onwards, but their use in Antiquity has hitherto been unknown.
Breast cancer researchers at the University of Notre Dame have identified a pair of proteins, CXCL5 and CXCR2, critical for spreading breast cancer to bone. These proteins cause cancer cells to rapidly reproduce and spread throughout the bone and marrow.
A multistakeholder coalition has issued clinical recommendations to prevent secondary fractures in older adults with osteoporosis. The guidelines recommend increased communication with patients regarding fracture risk and mortality outcomes, as well as fracture risk reduction strategies.
A team of researchers has developed a method to screen bone samples for collagen using near-infrared spectrometry, reducing the need to destroy valuable remains. This breakthrough could enable scientists to analyze ancient DNA and gain insights into human history.
New research suggests that mosasaurs used a unique swimming style that combined elements of both tail and forelimb movement. This dual approach may have allowed them to swim faster and more efficiently than previously thought, with powerful bursts of speed adding to their cruising ability.
A new report highlights the limitations of cell-based therapies for treating musculoskeletal diseases like arthritis and osteoporosis due to insufficient clinical evidence. The task force recommends specific guidelines for preclinical and clinical investigations to develop more effective treatments.
A study published in JCI Insight found that Apolipoprotein E interferes with bone healing in older individuals, leading to weaker bones and increased risk of re-fracture. Researchers discovered that reducing ApoE levels can reverse aging effects on the bones, promoting faster and more effective healing.
Researchers develop non-invasive method to evaluate bone structure using ultrasound, potentially enabling early osteoporosis detection and treatment assessment. The technique also shows promise in distinguishing between tumors and healthy tissue in laboratory rats.
A recent study of a 10 million-year-old fossil has revealed that human ancestors may not have been as ape-like as previously thought. The Rudapithecus pelvis suggests that early human ancestors had more flexible lower backs, allowing them to stand upright and walk efficiently on two legs.
Researchers analyze fish bones from Early Neolithic Jiahu site in Henan Province, China, and find evidence of managed carp aquaculture from 6200-5700 BC. The study's findings suggest a sophisticated system of aquaculture development in prehistoric East Asia.
Researchers at the University of Texas at Austin discovered that Komodo dragon armor is designed to protect against other dragons, not predators. The unique bone structure, featuring four distinct shapes, provides extensive coverage and suggests that young Komodo dragons do not have armor until adulthood.
A recent study published in the Journal of Bone and Mineral Research found that calorie restriction can have negative effects on bone health, even when paired with regular exercise. Mice subjected to calorie restriction experienced an increase in bone marrow fat and a decrease in overall bone density.
Researchers discovered how breastfed babies absorb large amounts of calcium, building healthy bones. This mechanism could be key to treating osteoporosis and other bone diseases later in life.
A new study found that weight loss interventions among older adults with obesity result in persistent loss of hip bone mineral density, regardless of subsequent weight regain. Losses in both fat mass and lean mass contribute to reduced bone health.
Researchers investigated melatonin's role in preventing bone loss during space flight using cultured goldfish scales. They found that melatonin suppresses bone resorption by stimulating osteoblasts to produce CALCITONIN. This suggests melatonin could serve as a prophylactic drug to prevent bone loss of astronauts.
Researchers discovered a dose-related decrease in bone density with high doses of vitamin D, contrary to initial predictions. Vitamin D supplementation above recommended levels (400-2000 IU daily) was not associated with an increase in bone density or strength.
Researchers analyzed strontium, carbon, and nitrogen isotopes in jaguar scat to identify prey habitats. The study found that jaguars in Belize were not competing with livestock for resources, providing reassurance for conservation efforts.
Researchers analyzed ear ossicles from 20 juveniles excavated in 18th-19th century burial grounds to understand maternal pre-pregnancy and late pregnancy diets. The study provides a unique link between diet and early pregnancy health.
Duke researchers identify biochemical receptor that can reverse bone degradation caused by osteoporosis, offering new potential treatment option. The study found that activating the adenosine receptor A2B can halt and even reverse bone deterioration in mouse models of osteoporosis.
Researchers at the University of Birmingham found that fortifying wheat flour with vitamin D alone would save the public purse £65 million by reducing healthcare demands. Combining this with targeted supplementation could prevent 33% of cases, particularly among vulnerable groups.