Articles tagged with Bones
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A study by UT Southwestern Medical Center researchers found that patients who broke bones in traumatic accidents often experience Post-traumatic Stress Disorder (PTSD), with almost 51% of civilian orthopaedic trauma patients displaying symptoms. The more severe the injury, the higher the likelihood of PTSD.
Researchers analyzed data from 149,524 postmenopausal women to identify predictors of bone fractures. Women with low T scores or previous fractures were found to be at increased risk, highlighting the need for targeted interventions.
Exercise has been shown to improve physical fitness, lower back pain, and cholesterol levels in early postmenopausal women. After 26 months, the exercise group experienced significant increases in physical fitness and reductions in bone loss compared to the control group.
A study found that MDCT was more accurate than plain film in detecting bone loss near the prosthesis (100% vs 67%) and fractures (100% vs 94%). MDCT also showed improved detection of loose components (61% vs 54%). The study suggests MDCT should be performed for patients with questionable x-rays or those needing surgery.
A recent study of 413 pediatric knee MRI exams found that bone bruises in adolescents frequently occur without accompanying injuries to the menisci, ligaments, or cartilage. This discovery could lead to more conservative treatment approaches and reduced anxiety for patients and families.
Researchers at Rice University have developed a biodegradable implant that can release growth factors to stimulate bone growth in critical-size defects, aiding the body's natural regeneration process. This innovative approach aims to provide patients with their own tissue and eliminate risks associated with existing treatments.
Researchers at Purdue University have discovered self-assembling nanotubes that attach better to titanium-coated implants than uncoated ones, promoting new cell growth and potentially leading to longer-lasting artificial joints. The nanotubes offer promise in biomedical applications and could be tailored for specific parts of the body.
The study reveals that oysters' immune blood cells contain rhombohedral-shaped crystals used to form shell. The research aims to understand biomineralization for potential breakthroughs in medical and material sciences.
Researchers have discovered the remains of a 9,500-year-old human-cat burial on Cyprus, providing the oldest known evidence of cat taming. The find, published in Science journal, suggests that humans may have begun taming wild cats earlier than previously thought, around 11,000 years ago.
A study led by Michigan State University scientists found that lyophilization does not improve the safety of bones and tissues for transplantation, contradicting current clinical beliefs. The researchers tested five samples each of infected bone and tissue through lyophilization and found that the virus survived the process.
A new study reveals that children under 10 are at risk for sustaining multiple injuries, with boys being 10% more likely to seek medical attention than girls. The study also found that certain ages are more susceptible to specific types of injuries, such as burns and poisoning between the ages of one and three.
Dr. Soskolne has made significant contributions to scientific literature in the fields of oral pathology, bone physiology, and the pathogenesis of periodontal diseases. He developed an organ-culture model for studying bone remodeling, which has been used extensively to study bone physiology.
A Rice bioengineer has won the 'Create the Future' design contest with a device that uses acoustic waves to measure bone structural integrity. The OsteoSonic TM system offers advantages over existing radiological diagnostics and is currently undergoing testing.
A team of scientists at Stanford University re-analyzed the DNA samples from the alleged Romanov remains, finding significant discrepancies that challenge previous conclusions. The researchers argue that the original genetic tests were flawed due to contamination or degradation, which led to inaccurate results.
Type I diabetics experience bone loss due to insufficient amylin production, which reduces osteoclast cell activity. Amylin injection or pathway activation may help correct this issue and alleviate osteoporosis.
A Baylor College of Medicine study reveals that the hormone amylin inhibits bone loss and resorption. Mice without amylin have less bone mass due to increased bone destruction, suggesting a potential therapeutic avenue for preventing osteoporosis in Type 1 diabetes patients.
Scientists give mice with damaged kidneys injections of BMP-7 to prevent adynamic bone disorder, a condition causing weakening and distortion of bones. The treatment is shown to be effective in normalizing bone cell counts and structures.
A study monitored sun exposure, diet and blood levels of vitamin D in 23 teenage girls from ages 10 to 13 years old. The results showed that almost half of the Bangor area girls had insufficient levels of vitamin D in their blood, with 17% having low levels in September.
A study published in Science has identified the Alox15 gene as a potential human therapeutic target for osteoporosis risk. The gene's over-activity leads to reduced bone density and increased risk of osteoporosis, but inhibitors of the gene's enzyme can improve bone mass and strength.
A study by Dr. Kimberly O'Brien found that adolescent pregnancy compromises a girl's ability to reach optimal bone growth, potentially leading to osteoporosis. Girls who consumed more calcium during pregnancy showed less bone loss when tested post-partum.
A study published in Journal of Bone and Mineral Research found that repetitive work tasks can cause pathological overloading of upper extremity bones in rats. The researchers observed tissue damage and inflammation within 3-6 weeks, suggesting the potential for early intervention to prevent further harm.
Researchers found that an anti-platelet drug, ML464, blocked bone metastases and reduced new tumor development in mice. The study provides a promising start to exploring the use of anti-platelet drugs as potential therapies for breast and prostate cancer.
Researchers successfully used gene-modified dendritic cells to induce apoptosis in collagen-specific T cells, reducing arthritis incidence and severity. Additionally, stem cell factor was found to drive hepatocyte proliferation after liver resection, while VLA-1 expression is crucial for T cell memory of previously encountered antigens.
Researchers at Purdue University have created a new type of metal alloy with nanometer-scale bumps that can stimulate the body to regrow bone and other tissues. This technology has the potential to improve artificial body parts, such as hip replacements, by reducing the rate of rejection and failure.
Researchers on the Old English Dictionary project found a heavy preponderance of 'for' compounds and the phrase 'to be on fire,' which originated in an Old English quotation. The study highlights the importance of understanding language as a conveyor of culture, revealing insights into social, political, and intellectual institutions.
UMHS researchers found poor bone quality in rats with high-dose radiation, suggesting new therapies to improve human treatment. The study uses a rat model to analyze the success and failure of distraction osteogenesis in irradiated cancer patients.
Researchers at the University of Rochester Medical Center have identified a key role for bone-forming osteoblasts in controlling the expansion of blood-forming stem cells. The discovery could lead to new treatments for bone marrow-transplant patients, who often face challenges due to limited stem cell availability.
Research reveals that bone cement containing antibiotics can effectively control bacterial growth in the immediate vicinity of the implant, but this effectiveness is short-lived. After just a few weeks, the concentration of antibiotics decreases, making it less effective against bacteria.
Rensselaer Polytechnic Institute researchers are awarded a $2.6 million NIH grant to develop engineered bone tissue that can promote faster and stronger bone healing, potentially treating bone injuries, hip replacements, and arthritis.
A large-scale study from Massachusetts General Hospital finds radiofrequency ablation (RFA) to be the most effective treatment for osteoid osteoma, a type of benign bone tumor. RFA offers a high success rate and low complication rate, making it an attractive alternative to traditional surgery and medication.
A study published in Radiology found that MRI can accurately detect bone invasion by soft-tissue sarcomas, with a sensitivity and specificity of 100% and 93%, respectively. This accuracy enables radiologists to confidently evaluate MR results for bone involvement, previously reserved for soft tissue involvement.
A new study found that Actonel maintained the size of calcium-based mineral crystals and the integrity of collagen structure over five years, preserving bone quality. This is significant because osteoporosis therapies should aim to reduce fracture risk, not just treat symptoms.
A major axis within bone cells regulates bone production and loss, providing a potential new target for treating debilitating osteoporosis. Local regulation of bone mass is now believed to occur primarily in the bone, not in the brain as previously thought.
A study of fossil records at Grotte XVI found that Neanderthals and Cro-Magnon both hunted a wide variety of game, including reindeer and red deer. The researchers also discovered a sharp drop in cave bear numbers from Neanderthal to Cro-Magnon times, suggesting competition for living space may have led to their extinction.
A new study found that combining osteoporosis medications, parathyroid hormone and bisphosphonates, does not provide additional benefits to patients. The trial of 238 postmenopausal women showed no significant improvement in bone density or anabolic effects when both drugs were used together.
A recent study found a dramatic increase in wrist fractures among children under 35 over three decades, with rising physical activity and declining milk consumption contributing to the trend. The research suggests that early-life dietary habits may impact bone development and increase fracture risk later in life.
Researchers at Columbia University discovered that D-beta-hydroxybutyrate restores impaired brain function and protects against neurodegeneration in mice with Parkinson's disease. The study supports a critical role for mitochondrial defects in the progression of the disease.
The overproduction of noggin during aging may result in impaired bone building and function, leading to net bone loss. Researchers suggest that recombinant BMP2 may prove useful in reversing age-related bone loss.
A study conducted at the University of Melbourne found that smoking is significantly linked to osteoporosis in women, particularly after menopause. Continuing high exposure to tobacco and greater sensitivity to smoking-induced bone loss are possible explanations for this link.
Immediate weight-bearing pressure can lead to fibrous tissue formation instead of normal bone, hindering implant performance. Bioengineers aim to determine the ideal loading amount and timing to prevent this issue and increase the success rate of implants.
A clinical trial found that oral sodium clodronate reduced the risk of symptomatic bone progression by 21% and mortality by 20% compared to placebo, but with limited statistically significant results due to small population size. However, side effects were common, particularly in older patients.
Researchers discover that estrogen deficiency triggers immune system activation, leading to increased T cell proliferation and bone loss. This finding could lead to the development of new drugs that prevent postmenopausal bone loss without affecting reproductive organs.
A boy was diagnosed with acquired osteopetrosis after being given high doses of bisphosphonates to treat weak, painful bones. The condition results from excessive bone formation and can lead to fractures., Researchers emphasize the importance of carefully monitoring medications like bisphosphonates, especially in children.
Researchers highlight the growing concern of male osteoporosis, emphasizing genetic predispositions and secondary risk factors such as alcohol consumption and malnutrition. Dr. Rosen recommends early bone density testing for men over 55 with unexplained height loss or fracture history to identify potential treatment options.
Researchers develop scaffold that enables bone marrow cells to grow naturally without growth factors, promoting dense new bone growth. The technology has shown promising results in animal studies, with strong new bone replacing the scaffold in just eight weeks.
A 7-year study shows Actonel significantly reduces vertebral fracture incidence, with annualized rates of 4.7%, 5.2%, and 3.8% for the treatment group, respectively. Adverse events were similar to those in patients taking placebo during the first 5 years.
Researchers at U-M examined the effects of aging and menopause on bone health and found that natural estrogen withdrawal after menopause causes more significant bone loss. The study suggests that hormone replacement therapy may not be necessary for all middle-aged women with regular menstrual cycles.
Researchers have developed a new lentiviral vaccine that can induce robust immune responses in mice, offering a promising candidate for cancer therapy. Additionally, studies suggest that newborns may have a mature and functional immune response to infections, raising questions about neonatal vaccination strategies.
A Mayo Clinic case report reveals that long-term minocycline users are at risk of developing dental staining, causing blackish-blue appearance of the gums. The study emphasizes the need for collaboration between medical and dental professionals to ensure proper oral health management.
A recent study evaluated the medical costs of osteoporosis therapies and found that patients taking weekly Fosamax had lower GI-related medical costs compared to those taking daily or weekly doses. The analysis, conducted with a large medical claims database, also revealed that treating patients with a weekly dose of Fosamax versus a d...
Researchers found that there exists a critical nanometer size where mineral particles in biocomposites become insensitive to flaws, maintaining strength equivalent to a perfect crystal despite inherent defects. This phenomenon suggests that the engineering concept of stress concentration at flaws is no longer valid for nanoscale design.
A 12-month study comparing FOSRENOL and calcium carbonate found that FOSRENOL led to a 'considerably better outcome' on bone histology, with halved rates of patients with osteomalacia, adynamic bone disease, or hyperparathyroidism. This contrasts with the calcium carbonate group, which showed an increase in these conditions.
A study published in the Journal of Vascular Interventional Radiology suggests that percutaneous radiofrequency ablation can be an effective treatment for osteoid osteomas, with all eight patients achieving complete pain relief. The use of CT fluoroscopy enhanced imaging guidance improved precision and success rates.
A recent study shows that whole body PET scans are twice as sensitive as CT scans in detecting breast cancer spread, with a higher accuracy rate of 93% compared to 46%. This breakthrough technology also offers less radiation exposure to patients, making it a more efficient and safer option.
A study found that mice genetically engineered to lack a molecule called Stem Cell Antigen-1 (Sca-1) experienced normal bone development but exhibited decreased bone mass and brittle bones as they aged. The researchers believe that defective maintenance of stem cells may contribute to age-related osteoporosis in humans.
Rice University researchers aim to develop new, noninvasive treatment options for damaged cartilage by using patient's own bone marrow cells to grow more cartilage. The goal is to create a biodegradable scaffold that promotes cartilage formation and avoids problems associated with current therapies like allografting.
Scientists have discovered fossilized evidence of a dinosaur, Majungatholus, that regularly consumed members of its own species. The discovery expands our understanding of dinosaur relationships and provides insight into the animal kingdom's common practice of cannibalism.
A study of wild black bears found that they recover from bone loss caused by inactivity through a mechanism involving increased bone formation during remobilization. This suggests that hibernating bears may minimize bone loss and completely recover lost bone, providing potential insights for treating osteoporosis.
Researchers evaluated 83 children with repeated short courses of oral glucocorticoids and found no detectable cumulative negative effect on bone formation. The study also showed no impact on the children's weight or height.
Researchers from the University of Washington and Southern Methodist University conclude that climate change, not humans, was responsible for the extinction of Pleistocene mammals in the New World. The study found no evidence linking Clovis people to the extinctions, contradicting previous 'overkill' hypothesis.