Articles tagged with Bones
A study published in the Journal of Bone and Mineral Research found that adults with osteoporosis are at a higher risk of developing cardiovascular disease. The research identified several key risk factors, including older age, smoking, and use of anti-hypertensive medications.
Researchers at Tohoku University have created a scaffold that supports the growth of new bone in large jaw defects in mice, bringing them closer to addressing the issue of aging jaw bone loss in humans. The technique uses a polylactic acid scaffold and has shown promise for treating large bone defects.
Researchers have found a 30-million-year-old beaver fossil that challenges previous theories on the evolution of semi-aquatic beavers in North America. The discovery, published in Royal Society Open Science, suggests that these animals may have evolved to swim earlier than previously thought and were likely adapted for aquatic life.
A study found that elevated blood levels of chemokine CXCL9 predict the risk of osteoporotic hip fracture in men. Researchers discovered a significant association between CXCL9 and hip fractures in a cohort of Chinese men, highlighting the potential for early interventions targeting CXCL9 to prevent hip fractures.
A new study reveals a previously unrecognized level of heterogeneity and specialization of endothelial and mesenchymal cells in the bone marrow. By integrating single-cell gene expression data, researchers identified 14 endothelial and 11 mesenchymal subclusters, providing insights into blood stem cell self-renewal and differentiation
A Texas A&M study sheds light on a major health concern for people with Down syndrome, who may not heal from bone fractures. The researchers found that the glue-like cartilage that helps bones heal doesn't form properly in individuals with DS, leading to devastating health impacts.
Researchers at the University of Connecticut have developed a potential breakthrough treatment for rotator cuff tears, using an advanced polymer to stimulate regeneration of both the tendon and muscle. This approach addresses the real problem of muscle degeneration and fat accumulation that often leads to re-injury after surgery.
Researchers at IISc identified a way to estimate ancient seawater temperature by analyzing otoliths from fish ears, which hold clues to water type and age. By correlating calcium isotope ratios with seawater temperatures, they found a powerful tracer of water temperature that can be applied to fossilized samples.
A recent UK-based study has revealed that vegetarian women have a 33% higher risk of hip fracture compared to regular meat-eaters. The research found that vegetarians had lower intakes of protein, calcium, and other micronutrients, which are crucial for bone and muscle health.
A new mathematical framework predicts the most effective combinations of drugs to treat postmenopausal bone loss in patients. The model identifies optimal orderings that boost bone density and reduce long-term bone loss, improving treatment outcomes.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that vegan participants who engaged in regular resistance training had stronger bones than those who did not. The study also showed that vegans and omnivores who performed resistance training had similar bone structure.
Researchers discovered that vitamin K acts as an antioxidant, inhibiting ferroptotic cell death and identifying FSP1 as the warfarin-insensitive enzyme responsible. This finding has implications for treating Alzheimer's disease and acute organ injuries.
Researchers found that daily consumption of small portions of Jarlsberg cheese increased osteocalcin, a hormone associated with strong bones and teeth, without boosting harmful cholesterol levels. The effects were specific to Jarlsberg and not seen in other cheeses.
Researchers have identified a new protein called IFT80 that regulates osteoclasts, the cells responsible for breaking down bone. The study found that mice lacking IFT80 developed severe osteopenia, highlighting its potential as a therapeutic target for treating bone loss diseases.
A recent study published in The New England Journal of Medicine found that supplemental vitamin D did not lower the risk of fractures in healthy US adults. The research, which involved over 1,991 incident fractures and 5.3 years of follow-up, also showed no effects on major osteoporotic fractures or wrist/pelvic fractures.
A recent study published in The Journal of Bone and Joint Surgery found that only 35.9% of articles reported patient race, 15.4% reported ethnicity, and 8.3% reported income. Including demographics in multivariable analyses is crucial to determine the applicability of study results to diverse patient populations.
A new study found evidence that multituberculates, an extinct group of mammals, likely reproduced in a placental-like manner. This discovery questions the long-held idea that marsupials were less advanced than placentals in terms of reproductive strategy.
A study published in Pediatrics found that there is no consistent medical definition of growing pains, with over 93% of studies not referencing growth or age. The condition's vague and contradictory definitions raise questions about its connection to growth and cause.
Researchers found that CXCL9 levels were higher in pre-fracture blood samples of Chinese men with subsequent hip fractures, improving the prediction of osteoporotic hip fracture risk in men. In contrast, no association was found between CXCL10 and hip fracture risk in either gender.
Researchers from Tianjin Medical University General Hospital review sarcopenic obesity's impact on liver disease, including nonalcoholic fatty liver disease and cirrhosis. The study aims to clarify the pathogenesis of sarcopenic obesity and identify potential therapeutic avenues.
A KAUST-developed nanotechnology platform uses tiny iron wires that bend in response to magnetic fields to accelerate bone cell formation. Bone-forming stem cells grown on the moving substrate transform into mature bone much faster than usual, potentially paving the way for more efficient regeneration of bone.
Researchers found that giant pandas and their ancestors used a thumb-like structure to grip bamboo, dating back at least six million years. The modern panda's thumb is shorter but has a hook for better grasp and flattened outer surface for weight distribution.
A fossilized wrist bone from a 6-7 million-year-old giant panda ancestor reveals the earliest evidence of a bamboo diet and the evolution of its unique 'thumb' structure. The discovery sheds light on how this adaptation allowed ancient pandas to thrive on a low-nutrient bamboo diet.
A new study published in Scientific Reports found that astronauts who spent six months in space experienced significant bone loss upon their return to Earth, with weight-bearing bones only partially recovering. The researchers discovered that the bone loss was comparable to decades of age-related bone loss on Earth.
Fossils found in the 'Cradle of Humankind' in South Africa are estimated to be between 3.4 and 3.7 million years old, making them older than previously thought. This new age range places these fossils at the beginning of the Australopithecus era, challenging previous theories that they were near the end.
A study of 56 transgender youth found that longer treatment with puberty-delaying medications was associated with lower bone mineral density. The researchers recommend discussing the impact of these medications on bone health and exploring interventions to improve bone health.
Research found that patients using insulin have a higher risk of fractures compared to those using metformin, particularly in non-obese and well-controlled diabetic patients. Routine fracture risk assessments are recommended for these individuals.
A UNLV study analyzed nearly 30,000 broken bone cases and found that smoking increases the risk of breaking a bone by as much as 37%. The study also found that men are more likely to experience fractures, particularly in the wrists, spine, and shoulders, due to nicotine's negative impact on bone cells and calcium absorption.
Researchers have re-evaluated chicken remains from over 600 sites worldwide, revealing that domestication occurred around 1,500 BC in Southeast Asia. Chickens were initially regarded as exotica and only later used as a food source.
A new study published in PLOS Genetics found that a person's height impacts their risk for multiple diseases, including atrial fibrillation and varicose veins. The study also uncovered associations between greater height and a higher risk of peripheral neuropathy and skin bone infections.
A Swedish study found that rates of adverse events after hip replacement surgery are essentially the same for procedures performed by female and male orthopaedic surgeons. The overall rate of adverse events was lower for THA procedures performed by female surgeons, at 6%, compared to 7% for male surgeons.
A study identified an 18-base osteogenetic ODN (iSN40) that promotes the differentiation of mouse osteoblasts and induces the expression of genes required for bone formation. This discovery offers a promising treatment option for osteoporosis, which affects 200 million people worldwide.
The discovery of a 164,000- to 131,000-year-old Denisovan tooth in Laos provides significant insights into the species' geographic range. The ancient tooth's shape and similarity to teeth found on the Tibetan Plateau suggest that Denisovans inhabited Southeast Asia, particularly northern Laos.
Researchers analyzed ancient incense samples from a Tang Dynasty Buddhist temple and found evidence of exotic spices like elemi and frankincense. The findings provide insight into the complex role of incense in religious rituals and court activities during this period.
A Kyoto University study has discovered that c-type natriuretic peptide facilitates intracellular calcium signaling in chondrocytes to stimulate long bone growth. This finding may lead to the development of new bone growth-stimulating agents for treating developmental disorders.
Researchers developed a novel 'Wikiguideline' approach to establish medical guidelines, leveraging online collaboration and high-quality data. The method was tested using osteomyelitis, an infection of the bone, and found sufficient data for only two recommendations: increasing oral antibiotic therapy and limiting therapy duration.
A new study published by The Endocrine Society suggests that exposure to per- and polyfluoroalkyl substances (PFAS) and phthalates may impair bone health in male teenagers. Researchers analyzed urine and blood samples from over 800 adolescents, finding an association between certain PFAS and phthalates and reduced bone mineral density.
Research reveals high rates of parasitic worm infections in ancient British populations, particularly during the Roman and Medieval periods. The study sheds light on the lives and habits of past populations, providing insights into public health measures.
A team of biologists identified a protein involved in the spread of breast cancer to bones. The discovery confirms the importance of cellular plasticity during the metastatic process and could lead to new treatments. ZEB1, a protein that increases cell plasticity, was found to direct cells with metastatic characteristics to bones.
Researchers found that NSAID use negates the bone-protective effects of bisphosphonate clodronate on preventing osteoporotic fractures. The study suggests caution in extrapolating these data to more widely used bisphosphonates, as concomitant usage may lead to reduced fracture risk.
A bundled care Medicare program has led to reductions in some outcome disparities for Black patients compared to White patients undergoing hip and knee replacement surgery. The Comprehensive Care for Joint Replacement (CJR) Model has improved key outcomes such as hospital readmission rates, length of stay, and Medicare payments.
Researchers found that favorable local climate change led to chronic warfare in ancient Peru, as neighboring regions experienced droughts and migrants put pressure on the agricultural economy. The study suggests that climate change can harm all populations, either directly or indirectly, through destabilization and refugee crises.
A new series of expert reviews explores less common causes of bone loss, including pregnancy-associated osteoporosis and anorexia nervosa-related osteoporosis. The reviews provide comprehensive information on these unusual conditions and their impact on bone health.
Patients with lower levels of sex hormones are more likely to undergo surgery for rotator cuff tears, according to a study published in The Journal of Bone & Joint Surgery. Estrogen deficiency was associated with a 48% higher incidence of rotator cuff repair in women, while testosterone deficiency was linked to an 89% higher rate in men.
A study found that mothers in a 19th century Dutch village had low rates of breastfeeding, likely due to their busy work schedules and easy access to cow's milk. Researchers analyzed the remains of 277 individuals and found little evidence of breastfeeding, surprising given the community's cultural associations with breastfeeding.
Researchers at UCLA found that premenopausal women with low levels of anti-Mullerian hormone are at a higher risk of experiencing significant bone loss within two to three years. The study suggests that measuring AMH levels could help physicians identify women at risk and provide targeted treatment.
A recent study suggests that eating nutrient-rich prunes every day may benefit bone health in postmenopausal women by reducing inflammatory factors. The research found significant reductions in inflammatory markers in prune-eating groups compared to a control group.
Scientists at Texas A¼M University have created water-stable, 2D covalent organic framework nanoparticles that can guide human mesenchymal stem cells to form bone tissue. The new technology has the potential to impact the treatment of bone regeneration and improve drug delivery.
Teréza Hough, CEO of the National Osteoporosis Foundation South Africa, has been awarded the IOF CNS Medal for her outstanding contributions to bone health advocacy. Her work in raising awareness and advancing education among the public and healthcare professionals in South Africa is recognized globally.
Professor René Rizzoli has been recognized for his significant and longstanding contribution to the advancement of osteoporosis research through his work on bone metabolism and mineralization. He is a respected researcher, clinician, and leader in the field of osteoporosis, with a strong focus on prevention and treatment.
The Virtual WCO-IOF-ESCEO 2022 Congress will feature leading experts on osteoporosis, osteoarthritis, and musculoskeletal diseases, with a focus on new clinical research and advances in prevention and patient care. Prestigious awards will also be presented.
Professor Antonio Cherubini has made significant contributions to the field of geriatric medicine and musculoskeletal diseases. He is recognized for his work on aging, bone health, and age-related diseases.
The International Osteoporosis Foundation awarded five young researchers for their groundbreaking work on the role of nutrition in musculoskeletal health. The winners, from Australia, India, and Switzerland, were recognized for their studies on vitamin K1 intake, calcium sources, and dietary inflammatory index.
Researchers at UC Davis have developed genetically modified lettuce producing a drug to protect against bone density loss in microgravity. The transgenic lettuce combines parathyroid hormone with an antibody protein, allowing for stable production and potential self-administration by astronauts.
Researchers create transgenic lettuce that expresses a bone-stimulating hormone, which could help prevent osteopenia in astronauts and resource-limited areas on Earth. The lettuce would need to be consumed daily by astronauts to get a sufficient dose of the hormone.
A new study suggests that mummification in prehistory was more common in Europe than thought, dating back to 8,000 years ago. The researchers found evidence of desiccation and hyperflexion in skeletal remains from the Sado Valley in Portugal.
Chronic liver injury triggers bone loss through the liver-bone axis, characterized by an imbalance of PP2Ac® and LCAT. This study reveals the molecular mechanisms behind HOD disease progression.
Researchers at Osaka University used advanced microscopy to visualize extracellular vesicles secreted by osteoblasts, identifying a subset that limits bone formation and stimulates osteoclast differentiation. This finding could lead to new treatments for bone diseases.
Researchers at RMIT University used high-frequency sound waves to turn stem cells into bone cells, overcoming challenges in mass production and pain associated with extraction. The innovative treatment is faster, simpler, and more efficient than existing methods.
Researchers uncovered bone remains of a first-generation African individual from Senegambia, buried in a Portuguese shell midden 350 years ago. The genetic signature and dietary analysis indicate that he was forcibly translocated to Portugal via the Trans-Atlantic Slave Trade.