Articles tagged with Fission Yeast
Researchers at Kumamoto University have developed a new rum using the rare fission yeast Schizosaccharomyces japonicusponicus, producing fruity esters and complex aromas. The resulting 'JAPONICUS RHUM AGRICOLE' offers layered flavors reminiscent of ripe banana and apple.
Researchers from The University of Osaka discovered that loss of heterochromatin can trigger genetic changes leading to chromosomal rearrangements and diseases like cancer. Accumulation of R-loops at pericentromeric repeats was found to be a key mechanism in this process.
A research team sheds light on Dmc1 filament assembly mechanisms using single-molecule experiments. Swi5-Sfr1 and Hop2-Mnd1 proteins regulate Dmc1 assembly through distinct mechanisms, promoting efficient strand exchange during homologous recombination.
Researchers discovered that Dis1 protein promotes microtubule shortening in fission yeast through catastrophe, a process where growing microtubules suddenly shorten. This finding challenges the conventional view of microtubule stabilization and has long-term applications for therapy and artificial cell segregation.
Researchers have discovered a family of selfish genes, wtf, that have survived for over 100 million years in yeast, contradicting established beliefs on their longevity. These 'killer meiotic drivers' transmit themselves to half of offspring and destroy reproductive cells without being suppressed by natural selection.
The study found that one pheromone operates strictly while the other is free to undergo diversification, a mechanism that may lead to reproductive isolation and speciation. This asymmetric system allows for flexible adaptation to mutational changes while maintaining recognition of mating partners.
Researchers at OIST Graduate University challenge cohesin's ring-shaped model by demonstrating that a mutation can't break down the complex, suggesting it may have a different structure. A new hold-and-release model proposes cohesin is like a jaw that holds chromatids in place and then opens to allow chromatin to move.
Scientists have identified seven key proteins in the Zika virus genome that may be responsible for its damaging health effects. The study provides valuable clues for future research on how the virus interacts with human cells and how to develop treatments or prevention strategies.
The PomBase database provides a comprehensive resource for studying fission yeast and its relevance to human diseases. The database contains counterparts of over 300 human disease genes, enabling researchers to study mechanisms involved in cell growth and division.
Researchers have discovered new functions of Aurora enzymes in fission yeast, which could lead to improved cancer treatments. The study used phosphoproteomics to identify dozens of new substrates for the enzymes, revealing roles in chromatin regulation and DNA protection.