Articles tagged with Urine
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A long-term study published in BJU International found that tension-free vaginal tape (TVT) is a highly effective option for treating urinary incontinence. TVT surgery involves placing a mesh tape under the urethra to prevent accidental urine release, with high cure rates reported at 17 years after surgery.
A US researcher has received a grant to investigate the role of ALCALM in lupus, a complex autoimmune disease. The study aims to understand how ALCALM drives the immune system to attack healthy tissues, and potentially find new treatments or even a cure for lupus.
Scientists at the University of Manchester successfully produced human kidney tissue within a living organism that is able to produce urine. The new structures contain most of the constituent parts present in human nephrons, including proximal tubules and Bowman's capsule, and have been linked to the vasculature of mice.
Researchers at Georgia Institute of Technology have identified two urinary chemicals, trigonelline and homarine, that trigger a warning response in mud crabs when exposed to blue crab urine. This finding has implications for understanding ecological balances in marine ecosystems and informing better management of fisheries.
Scientists discovered that specific metabolites in blue crab urine suppress mud crab foraging by 60% and 67%, respectively. This finding has significant implications for understanding chemically mediated interactions in marine ecosystems.
Researchers at Nagoya University have developed a novel medical device that can efficiently capture extracellular vesicles in urine, potentially leading to early diagnosis of cancer. The device surpasses existing methods and shows promise for non-invasive testing, including a simple urine test.
Researchers at Max Delbrück Center find GRHL2 protein crucial for concentrating urine and maintaining salt levels in the kidneys. Genetically modified mice lacking GRHL2 produce more diluted urine, highlighting its importance for regulating body fluids.
A pilot study in northeastern British Columbia detected high concentrations of muconic acid, a degradation product of benzene, in the urine of pregnant women. The median concentration was approximately 3.5 times higher than in the general Canadian population, raising concerns about the health impacts of living near fracking sites.
A new Brazilian study found that pregnant women with confirmed Zika diagnosis should be tested multiple times due to the intermittent presence of the virus in their urine. The study detected Zika virus in some women's urine for up to seven months after previous tests indicated a non-existent viral load.
Researchers have developed a wireless sensor and smartphone app that can detect amphetamines in human urine in seconds, with unprecedented sensitivity and low risk of false-positive results. The prototype device is portable enough to be worn as a bracelet and costs around $50 to produce.
Scientists found that metabolic changes occur soon after quitting smoking and can lead to improved lung function and reduced heart attack risk. The study identified 52 metabolites altered by smoking, with several showing reversible changes towards a nonsmoker's profile.
Researchers identified a potential biomarker, glycolate, that could stay in urine up to 20 hours after GHB ingestion. This finding could lead to tests with greater detection windows and less sample manipulation required.
Scientists found that certain compounds produced by gut bacteria can predict how animals will respond to high-fat diets, including weight gain and tolerance to glucose. The study uses urine chemical signatures to identify individuals at risk of obesity and related health conditions.
Researchers found that urinary cortisol levels were strongly associated with asymptomatic coronary heart disease in both women and men. Surprisingly, dopamine was inversely related to heart risk, indicating higher levels are linked to lower coronary calcium buildup.
A new enhanced test, EQUC, detects significantly more bacteria in urine samples than the standard culture, leading to improved diagnosis and treatment of urinary tract infections. The study enrolled 150 urogynecologic patients and found that EQUC identified 110 species of bacteria, while the standard culture only identified 50 percent ...
Researchers found that viral acute respiratory infections (ARIs) in infants may lead to oxidative stress and recurrent wheezing in early childhood. Oxidative stress is an imbalance between free radicals and antioxidants in the body, and measuring it in urine samples during a viral ARI may predict the development of recurrent wheeze.
A new study published in Clinical Microbiology and Infection found that almost all women with uncomplicated urinary tract infections (UTIs) had evidence of bacterial infection, including Escherichia coli and Staphylococcus saprophyticus. This suggests that traditional urine testing may not be necessary for women with UTI symptoms.
A recent study found that patients with drug-resistant bacteria in their urine or stool samples have a significantly increased risk of developing drug-resistant sepsis. Researchers discovered that the risk is highest soon after detection and can persist for up to three years.
Researchers discovered a protein cocktail in urine that can distinguish between viral infection and organ rejection. The new test may enable early detection of transplant failure, improving outcomes for patients.
Researchers found that consuming more salt led to reduced water intake and conserved body water by triggering a mechanism in the kidneys. The study suggests that urea plays a crucial role in maintaining proper water balance and challenges previous assumptions about its function.
Research suggests that low urine ammonium excretion may identify individuals with chronic kidney disease at high risk of progression or death. Low ammonium levels also predict increased risk of developing acidosis and a higher mortality rate.
Researchers have identified a set of molecules in urine that are present in 90% of prostate cancer patients but not in healthy individuals. This discovery could lead to the development of a non-invasive test for early detection of prostate cancer, potentially reducing unnecessary biopsies and improving patient outcomes.
Case Western Reserve University researchers have developed a breakthrough technique to create durable stem cells directly from urine, providing an ethically sound and clinically relevant model for studying Down syndrome. The new method represents a significant improvement in induced pluripotent stem cell technology.
A recent Yale-led study found that marathon running can cause short-term kidney injury in runners, with 82% of participants showing signs of Stage 1 Acute Kidney Injury after the event. The researchers attribute this to sustained rises in core body temperature, dehydration, and decreased blood flow to the kidneys.
Researchers have identified a protein in urine samples as a potential biomarker for ALS, allowing for monitoring disease progression and assessing therapy effectiveness. Studies found patients with higher levels of the protein survived longer, suggesting it could be used to predict disease outcome.
Researchers use artificial sweetener acesulfame potassium to estimate urine presence in pools and detect potential health hazards, finding high concentrations in swimmers' urine, exceeding tap water levels.
Research suggests exposure to low doses of pyrethroid insecticides may be associated with behavioral disorders in children. Higher levels of specific metabolites were linked to internalising and externalising behaviors.
In patients with diabetes, an immune system receptor called Toll-like receptor 4 is activated by dying cells and bacteria, leading to inflammation and bladder dysfunction. Preventing this activation enables the bladder wall to remain strong and elastic.
A new urine test can quickly detect whether a person has a healthy diet by measuring biological markers created by the breakdown of foods. The test provides an instant indicator of whether a person is eating healthily, promising to revolutionize the way we assess diet quality.
A meta-analysis published in Neurology found that people with protein in their urine are 35% more likely to develop cognitive impairment or dementia. Chronic kidney disease shares many risk factors with dementia, including high blood pressure, diabetes, and high cholesterol.
A study found that 40% of participants could smell the distinct odor in their urine after eating asparagus, while 60% were unable to detect it. The researchers identified 871 genetic variants linked to asparagus anosmia and suggest future research on sense of smell receptors.
A new urine test has been developed to detect biochemical changes associated with fatigue in workers, which could reduce errors and prevent accidents.
Researchers at the University of Surrey have created a new diagnostic test for cocaine in urine and oral fluid, enabling sensitive and accurate detection. The compact mass spectrometer-based test offers quantitative data on cocaine levels, potentially revolutionizing scenarios requiring rapid drug testing.
A multinational study found that nearly one-fourth of children admitted to pediatric intensive care units worldwide develop acute kidney injury (AKI), which increases the risk of death. The study also revealed that severe AKI is associated with an increased need for mechanical ventilation and renal replacement therapy, highlighting the...
Researchers have developed a new metabolomics-based screening approach that can identify multiple different inborn errors of metabolism (IEMs) in a single urine sample. This method has the potential to detect numerous IEMs, which were previously detected in various bodily fluids such as blood and cerebrospinal fluid.
Researchers used NMR spectroscopy to identify a panel of 10 urinary metabolites associated with fetal growth and increased birth weight. Changes in these metabolites could explain 12% of the variation seen in birth weight, independent of other known predictors.
Scientists at the University of Missouri have developed a noninvasive procedure to identify individuals exposed to uranium within one year using hair and nail samples. The technique can also distinguish between natural and manmade sources of uranium, offering a significant advantage in detecting nuclear smuggling threats.
A new study from Oregon Health and Science University suggests that the type of bacteria present in the urinary tract may play a role in general health conditions like Urgency Urinary Incontinence (UUI). Women with UUI tend to have fewer diverse bacterial communities, while those with lower diversity experience more severe symptoms.
Researchers found strong biological evidence linking Zika virus infection to Guillain-Barré syndrome in a substantial number of patients. The study, published in The New England Journal of Medicine, supports the correlation with immunologic and viral evidence of Zika infection.
A new study in New Zealand found that higher stocking rates per grazing area led to less nitrogen leached to groundwater, contradicting the notion that more cows result in increased leaching. The experiment showed a decline in NO3-N leached per hectare with increasing stocking rate and decreasing nitrogen intake and output per cow.
Researchers found that males lost neurons detecting female pheromones after chronic exposure, while females showed no effect from male urine. This study explains differences among individuals and between the sexes through sensory experience rather than innate or hormonal factors.
A new study found that preterm infants with acute kidney injury (AKI) have higher levels of certain proteins in their urine compared to healthy infants. This could lead to better diagnostics and treatment for AKI in newborns, which is a common complication in premature infants and can predict poor clinical outcomes.
A study published in Clinical Journal of the American Society of Nephrology found that preterm infants with acute kidney injury have distinct protein profiles in their urine compared to those with healthy kidneys. This discovery could help physicians diagnose kidney health in newborns and improve treatment outcomes.
Researchers have developed a technique to help GPs and nurses identify young children most likely to have a UTI, enabling non-invasive urine sampling. The symptoms-and-signs-based clinical rule is superior to routine clinician diagnosis, reducing the need for unnecessary tests and increasing accurate diagnoses.
A study of wild female bonobos found that their sexual swellings are unreliable signals of fertility, allowing females to manipulate mate choice. The findings suggest that male bonobos may not be able to successfully compete over females due to the variability in swelling patterns.
A national effort showed that reducing catheter use and UTIs can be achieved through training and tools, saving money and suffering. By the end of an 18-month program, UTI rates dropped by a third in general wards, while catheter use decreased.
Scientists developed an approach for non-invasive testing of pregnant women with preeclampsia, identifying potential peptide biomarkers in their urine. The study found 35 potential biomarkers associated with the condition's severity.
A new study published in the American Journal of Clinical Nutrition found that urine tests are not reliable for detecting dehydration in older adults. The researchers tested 383 participants over 65 and found that urine tests were too low to be useful, missing some dehydrated individuals and incorrectly identifying others.
Scientists at the University of Texas at Austin developed a new method to rapidly detect single viruses in urine, including Ebola, Zika, and HIV. The technique is highly selective and can be used with urine straight from a person or animal, unlike other methods that require higher concentrations or purification.
Researchers at the Wyss Institute for Biologically Inspired Engineering have developed a novel, inexpensive method for detecting the Zika virus that could help slow its spread. The system uses a simple modular workflow comprising three steps: amplification, detection, and strain identification.
Researchers have discovered unique molecular signatures, known as saliva fingerprints, which may be used to detect diseases in a non-invasive and stress-free manner. These signatures are distinct from those found in urine samples and remain relatively stable despite dietary variations.
A new catheter infection alert system could prevent serious infections in millions of hospital patients and elderly people. The system changes the color of urine to detect bacterial blockages before they cause kidney failure and death.
Researchers at the University of Bath have developed a miniature fuel cell that can generate electricity from urine, offering an affordable and carbon-neutral way to produce power. The device has the potential to provide much-needed electricity to remote areas at low cost.
A new study finds that binturongs release a popcorn-like aroma from their urine, containing the compound 2-acetyl-1-pyrroline, to mark territories and attract mates. Researchers analyzed urine samples from 33 binturongs and identified 29 chemical compounds, with 2-AP being present in every sample.
A study of 70 elderly patients found that diverting urine through a single stoma resulted in lower operative times, blood loss, and hospital stays compared to ileal conduit diversion. Quality of life showed no significant difference between the two groups.
Research by University of York scientists shows how ketamine causes inflammation and cell death in the bladder, leading to cystitis. The studies found that direct contact with urinary ketamine is critical to the toxicity, ruling out systemic factors.
Researchers have developed smaller, cheaper microbial fuel cells that can efficiently produce bioenergy from urine. The new design increases power output and reduces costs compared to traditional models.
Researchers at Georgetown Lombardi Comprehensive Cancer Center have developed a method to quickly evaluate specific food compounds in human urine. The new tool looks for isothiocyanates found in cruciferous vegetables and could help scientists identify the most beneficial anticancer foods.
Researchers have discovered cells in the urine of preterm infants that can differentiate into mature kidney cells and provide protection against cell death. These cells could potentially be used as a treatment to regenerate damaged kidneys and improve outcomes for patients with kidney disease.
A new device can detect prostate cancer in urine samples using a gas chromatography sensor system, allowing for earlier diagnosis and potentially reducing the need for invasive procedures. The technology has shown promising results in a pilot study involving 155 men.