Articles tagged with Urine
Research by University of York scientists shows how ketamine causes inflammation and cell death in the bladder, leading to cystitis. The studies found that direct contact with urinary ketamine is critical to the toxicity, ruling out systemic factors.
Researchers at Georgetown Lombardi Comprehensive Cancer Center have developed a method to quickly evaluate specific food compounds in human urine. The new tool looks for isothiocyanates found in cruciferous vegetables and could help scientists identify the most beneficial anticancer foods.
Researchers have developed smaller, cheaper microbial fuel cells that can efficiently produce bioenergy from urine. The new design increases power output and reduces costs compared to traditional models.
Researchers have discovered cells in the urine of preterm infants that can differentiate into mature kidney cells and provide protection against cell death. These cells could potentially be used as a treatment to regenerate damaged kidneys and improve outcomes for patients with kidney disease.
A new device can detect prostate cancer in urine samples using a gas chromatography sensor system, allowing for earlier diagnosis and potentially reducing the need for invasive procedures. The technology has shown promising results in a pilot study involving 155 men.
A study by the University of Houston and UTMB found that urine drug screenings for chronic pain patients increase patient safety but raise the risk that patients won't return for future treatment. The screenings were associated with a higher no-show rate among patients, even those who tested negative.
A pair of socks embedded with microbial fuel cells powered by wearer's urine has successfully transmitted signals wirelessly. The system opens possibilities for using waste as a power source in portable and wearable electronics.
A small study found that surface nicotine was detectable on mothers' fingers and furniture in a neonatal unit, suggesting exposure to thirdhand smoke. Detectable levels of nicotine metabolites were also found in babies' urine samples, with potential health consequences for vulnerable premature newborns.
Researchers used urine-derived induced pluripotent stem cells (iPSCs) to model hypercholesterolemia and predict patient responses to cholesterol-lowering drugs. The study shows that these models can be used to test the efficacy of PCSK9 inhibitors, potentially paving the way for personalized treatment.
Researchers identified two chemical scents in female mouse urine that arouse sexual behavior in males, providing insight into mouse pheromones controlling behavior. The chemicals, waste products of steroid metabolism, were found to mimic the increased interest shown by males towards female urine.
A new urine screening method can detect even small amounts of chemicals resulting from secondhand marijuana exposure, addressing the challenge of assessing health effects. The developed method is 10 to 100 times more sensitive than current tests and could be used for large-scale population studies.
A Lund University study found that men with higher exposure to the chemical DEHP have lower sperm motility. This could lead to difficulties conceiving children. The study analyzed metabolite levels of DEHP in urine and semen quality among 300 young men.
A new treatment involving the removal of a protein called sFlt-1 from the blood has shown promise in prolonging pregnancy in women with preeclampsia. Pregnancy continued for an average of 8 days and 15 days in treated women, compared to just 3 days in untreated women.
Researchers at Barts Cancer Institute have identified a three-protein 'signature' in urine that can accurately detect early-stage pancreatic cancer with over 90% accuracy. This discovery could lead to a simple and inexpensive test for high-risk individuals, improving survival rates.
Researchers at Washington State University found no accumulated glyphosate in human milk despite widespread use of Roundup herbicide. The study's results contradict a previous, unverified claim and provide strong evidence for the safety of breast milk.
A new study by University of California, San Diego researchers has identified a pivotal player in diabetic kidney disease and a potential biomarker for diagnosing and monitoring chronic kidney disease. The study uses metabolomics analysis to clarify a central mechanism of action involving the NADPH oxidase proteins NOX1 and NOX4.
Researchers found that mice exposed to cat urine early in life can't avoid it later due to positive reinforcement and hormone changes. The molecule L-Felinine is responsible for this effect, blocking pregnancy and reducing litter size.
Researchers found that human urine's unknown factors interfere with bacterial FimH protein's ability to adhere to cells and switch off pilus production assembly. This exposes a crucial weakness in pathogen's ability to infect, making potential non-antibiotic treatments more effective
Researchers found that urine samples with higher acidity actually hindered bacterial growth due to the presence of specific compounds called aromatics. On the other hand, samples with less acidity showed increased activity of siderocalin, a protein that deprives bacteria of iron.
A study found that ERs misdiagnosed UTIs and STIs in women nearly half the time, resulting in unnecessary antibiotic use. The misdiagnoses were often due to similar symptoms and abnormal urinalysis results.
Researchers transformed bacteria into 'secret agents' that detect abnormal glucose levels in diabetic patients' urine. The bacteria are programmed using genetic transistors, allowing them to amplify and store molecular signals for months.
A new detailed guide provides advice on urinary catheter use, suggesting that far fewer hospital patients should receive them. The Ann Arbor Criteria recommend using catheters only in certain situations, such as for intensive care unit patients who need hourly urine volume measurement.
A study by Imperial College London identifies chemical markers in urine associated with body mass, providing insights into how obesity causes disease. The findings suggest that obesity has a 'metabolic signature' detectable in urine samples, pointing to processes that could be targeted to mitigate its effects.
Researchers have found that healthy newborns can alter and rid their bodies of bisphenol A (BPA), a chemical used in plastics and food packaging. The study challenged the current thinking on BPA toxicology and suggests that exposure to BPA in infancy may not be as harmful as previously believed.
Researchers from Loyola University Chicago Stritch School of Medicine found bacteria in the bladders of healthy women, contradicting the long-held belief that normal urine is sterile. This discovery has significant implications for understanding bladder health and disease, particularly lower urinary tract disorders.
Researchers developed a non-invasive method to screen for kidney cancer by measuring protein biomarkers in urine, achieving over 95% accuracy. The findings suggest the potential for an easy-to-use screening test, similar to mammograms or colonoscopies, to identify patients with kidney cancer at early stages.
A new study confirms that prenatal exposure to phthalates disrupts male sexual differentiation and correlates with lower fertility rates. Higher levels of human chorionic gonadotropin (hCG) in mothers' blood were associated with a lower anogenital distance in male babies.
A study by Nationwide Children's Hospital found that 43% of children with positive marijuana urine screens had test results consistent with narcolepsy or abnormal REM sleep patterns. The study highlights the importance of obtaining a urine drug screen before accepting a diagnosis of narcolepsy in adolescents.
Research presented at American Stroke Association's International Stroke Conference 2015 found that dehydration worsens stroke conditions. Almost half of ischemic stroke patients were dehydrated when admitted to the hospital, with hydrated patients experiencing better recovery outcomes and lower risk of worsening conditions.
Researchers at Loyola University Chicago Stritch School of Medicine identified a way to assess UTI risk in women after pelvic-floor surgery. The study found that certain urinary bacteria and antimicrobial peptides can identify women at increased risk, suggesting a potential method for improved prevention and treatment strategies.
A study of American women aged 45-55 found that soy helps alleviate hot flashes in those whose bodies can produce equol, a soy metabolite. Women with the most soy in their diet experienced 76% fewer hot flashes compared to those with less soy intake.
A 3-month course of levofloxacin following kidney transplantation did not prevent BK virus from appearing in the urine, according to a study. The intervention was associated with increased risk of adverse events like bacterial resistance.
A new study found that people are contaminated with several toxic flame retardants, including TCEP, a carcinogen linked to cancer and reproductive harm. The study identifies biomarkers for detection in urine samples, opening up research into the group of chemicals.
Researchers have developed a device that can detect markers of kidney disease and prostate cancer in urine samples, offering instant results and potentially higher accuracy. The device uses DNA sequences to latch onto disease markers, allowing for early detection at ultra-low concentrations.
A study found that thermal receipt paper can transfer high amounts of BPA to hands and blood levels after handling, particularly in women. This raises concerns about the potential health risks associated with prolonged exposure to BPA through daily activities.
A new study identifies a set of RNA molecules in urine and tissue samples that can detect prostate cancer with high sensitivity and specificity. These long noncoding RNAs have the potential to serve as biomarkers for early detection and diagnosis of prostate cancer, offering a promising approach to reduce overtreatment and morbidity.
A new technique called slug flow microextraction allows for the quick detection of drugs and monitoring of medical conditions using only a small sample of biological fluid. The method involves extracting target molecules from the sample and analyzing them with mass spectrometry, resulting in results in just minutes.
A study of wild East African chimpanzees found that females with high levels of male competition experience lower C-peptide levels, indicating energy deficit and potential weight loss. This can negatively affect their reproductive ability and fertility rates.
A urine HPV test showed high accuracy in detecting the virus compared to traditional cervical sampling methods. The test had a sensitivity of 87% and specificity of 94%, with improved results when using first-void urine samples.
Researchers at the University of Exeter Medical School have found that invisible blood in urine may be an early warning sign of bladder cancer. The risk of bladder cancer was 1.6% in people over 60 with invisible blood in their urine.
Scientists at Max Planck Institute identified pheromone in male Mozambique tilapia urine that boosts hormone production and accelerates oocyte maturation in females, triggering spawning. The discovery may help optimize aquaculture of food fish and control invasive species behavior.
A study of 70 people with relapsing-remitting multiple sclerosis found that high dietary salt intake was associated with more episodes of worsening symptoms and a higher likelihood of radiological signs of disease progression. Vitamin D levels also played a role, with low levels linked to the disease.
Researchers at Washington University School of Medicine have identified a potential new class of drugs, histone deacetylase inhibitors, that can dissolve kidney stones by reducing calcium and magnesium levels in the urine. The study shows promising results using small doses of two specific drugs, Vorinostat and trichostatin A.
A recent study found triclosan in all pregnant women's urine samples and in half of umbilical cord blood samples, posing developmental and reproductive problems. The exposure to these antimicrobial agents could contribute to antibiotic resistance and affect birth sizes.
Researchers at UTHealth Medical School have found misfolded prion proteins in the urine of 13 out of 14 patients with variant Creutzfeldt-Jakob disease, providing a new potential diagnostic tool. This breakthrough could lead to the development of non-invasive tests for diagnosis and monitoring.
Researchers have identified a connection between misfolded proteins associated with Alzheimer's disease and preeclampsia, potentially leading to improved diagnostic methods. A new urine test using Congo Red dye has already shown promise in identifying the presence and severity of preeclampsia.
Researchers at Imperial College London found a link between specific urine metabolites and spontaneous premature birth. Decreased levels of certain molecules were associated with poor fetal development and increased risk of diabetes.
A Dartmouth College study found that infant toenails are a reliable way to estimate arsenic exposure before birth. The researchers used plasma mass spectrometry to analyze infant toenails and found a significant correlation between maternal and infant toenail arsenic concentrations.
A new study published in Menopause found that calcium and vitamin D supplements can lead to high levels of calcium in the blood and urine in some older women. The risk was higher for those with lower initial calcium levels and increased age.
Research suggests certain bacteria in healthy women's bladders differ from those with overactive bladder (OAB), potentially contributing to the condition. Approximately 15% of women suffer from OAB, with an estimated 40-50% not responding to conventional treatments.
Researchers from Loyola University Chicago found bacteria in the bladders of healthy women, challenging the common belief that normal urine is sterile. The study also revealed differences in bladder bacteria between healthy women and those with overactive bladder (OAB), which may contribute to OAB symptoms.
A new study suggests that a simple urine test can detect blood clots in patients at risk, offering advantages over existing screening methods. The test evaluates fibrinopeptide B levels in urine, which are released when a thrombosis forms and then cleared by the body.
A study found that young adults who smoked water pipes in hookah bars had significantly elevated levels of nicotine, cotinine, and tobacco-related cancer-causing agents in their urine. This may increase their risk for cancer and other chronic diseases.
Researchers found that a diet rich in resveratrol did not reduce mortality rates or cardiovascular disease, contradicting previous expectations. However, they suggest that other polyphenols in these foods may still provide health benefits.
A novel electronic nose technique has been successfully used to discriminate between prostate cancer and benign prostatic hyperplasia in a proof-of-principle study. The eNose system demonstrated sensitivity and specificity comparable to traditional testing methods, such as prostate-specific antigen (PSA), with rapid and non-invasive re...
A new study published in Female Pelvic Medicine & Reconstructive Surgery found that a specialized yoga program can improve urinary incontinence in women by up to 70%. The six-week program helped women strengthen their pelvic floor muscles and reduce stress-related urine leakage.
A team of scientists at The Scripps Research Institute has deciphered the pheromone code used by mice to trigger countermarking behavior, which involves distinguishing territory from others.
Scientists have developed a new technique to convert astronaut urine into fuel and drinking water, reducing the waste burden in space missions. The Urea Bioreactor Electrochemical system efficiently converts urea into ammonia, which is then turned into energy with a fuel cell.
Researchers at Monell Chemical Senses Center and USDA found that immunization alters urine odor in similar ways, while immune-activated responses produce qualitatively different odors. This discovery suggests a pathway between immune activation and changes in body odor compounds, potentially enabling non-invasive disease detection.
A study of 208 patients with high blood pressure found that nearly a quarter did not take their medications as prescribed, while a smaller proportion only took part of the time. The findings suggest that a simple urine test can help identify which patients are not taking their meds properly and which may be experiencing treatment failure.