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New effects of ketamine abuse uncovered

Research by University of York scientists shows how ketamine causes inflammation and cell death in the bladder, leading to cystitis. The studies found that direct contact with urinary ketamine is critical to the toxicity, ruling out systemic factors.

SourceUniversity of York·JournalAmerican Journal Of Pathology·DateMar 18, 2016

Newborns in intensive care exposed to thirdhand smoke residue

A small study found that surface nicotine was detectable on mothers' fingers and furniture in a neonatal unit, suggesting exposure to thirdhand smoke. Detectable levels of nicotine metabolites were also found in babies' urine samples, with potential health consequences for vulnerable premature newborns.

SourceBMJ Group·JournalTobacco Control·DateDec 3, 2015

Testing for secondhand marijuana exposure

A new urine screening method can detect even small amounts of chemicals resulting from secondhand marijuana exposure, addressing the challenge of assessing health effects. The developed method is 10 to 100 times more sensitive than current tests and could be used for large-scale population studies.

SourceAmerican Chemical Society·JournalAnalytical Chemistry·DateOct 28, 2015

Researchers find key player in diabetic kidney disease through power of metabolomics

A new study by University of California, San Diego researchers has identified a pivotal player in diabetic kidney disease and a potential biomarker for diagnosing and monitoring chronic kidney disease. The study uses metabolomics analysis to clarify a central mechanism of action involving the NADPH oxidase proteins NOX1 and NOX4.

SourceUniversity of California - San Diego·JournalJournal of the American Society of Nephrology·DateJul 22, 2015

Study debunks common misconception that urine is sterile

Researchers from Loyola University Chicago Stritch School of Medicine found bacteria in the bladders of healthy women, contradicting the long-held belief that normal urine is sterile. This discovery has significant implications for understanding bladder health and disease, particularly lower urinary tract disorders.

SourceLoyola Medicine·JournalEuropean Urology·DateMar 30, 2015

Kidney cancer detected early with urine test

Researchers developed a non-invasive method to screen for kidney cancer by measuring protein biomarkers in urine, achieving over 95% accuracy. The findings suggest the potential for an easy-to-use screening test, similar to mammograms or colonoscopies, to identify patients with kidney cancer at early stages.

SourceWashU Medicine·JournalJAMA Oncology·DateMar 19, 2015

New technique yields fast results in drug, biomedical testing

A new technique called slug flow microextraction allows for the quick detection of drugs and monitoring of medical conditions using only a small sample of biological fluid. The method involves extracting target molecules from the sample and analyzing them with mass spectrometry, resulting in results in just minutes.

SourcePurdue University·JournalAngewandte Chemie International Edition·DateOct 9, 2014

Researchers find RNA molecules in urine and tissue that detect prostate cancer

A new study identifies a set of RNA molecules in urine and tissue samples that can detect prostate cancer with high sensitivity and specificity. These long noncoding RNAs have the potential to serve as biomarkers for early detection and diagnosis of prostate cancer, offering a promising approach to reduce overtreatment and morbidity.

SourceElsevier Health Sciences·JournalJournal of Molecular Diagnostics·DateOct 9, 2014

Back off: Female chimps stressed out by competing suitors

A study of wild East African chimpanzees found that females with high levels of male competition experience lower C-peptide levels, indicating energy deficit and potential weight loss. This can negatively affect their reproductive ability and fertility rates.

SourceSpringer·JournalBehavioral Ecology and Sociobiology·DateOct 7, 2014

High dietary salt may worsen multiple sclerosis symptoms

A study of 70 people with relapsing-remitting multiple sclerosis found that high dietary salt intake was associated with more episodes of worsening symptoms and a higher likelihood of radiological signs of disease progression. Vitamin D levels also played a role, with low levels linked to the disease.

Potential drug therapy for kidney stones identified in mouse study

Researchers at Washington University School of Medicine have identified a potential new class of drugs, histone deacetylase inhibitors, that can dissolve kidney stones by reducing calcium and magnesium levels in the urine. The study shows promising results using small doses of two specific drugs, Vorinostat and trichostatin A.

SourceWashU Medicine·JournalJournal of the American Society of Nephrology·DateAug 14, 2014

UTHealth researchers find infectious prion protein in urine of patients with variant Creutzfeldt-Jakob disease

Researchers at UTHealth Medical School have found misfolded prion proteins in the urine of 13 out of 14 patients with variant Creutzfeldt-Jakob disease, providing a new potential diagnostic tool. This breakthrough could lead to the development of non-invasive tests for diagnosis and monitoring.

SourceUniversity of Texas Health Science Center at Houston·JournalNew England Journal of Medicine·DateAug 7, 2014

Study debunks common myth that urine is sterile

Researchers from Loyola University Chicago found bacteria in the bladders of healthy women, challenging the common belief that normal urine is sterile. The study also revealed differences in bladder bacteria between healthy women and those with overactive bladder (OAB), which may contribute to OAB symptoms.