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Kidney stone mystery solved

New research reveals that a common genetic variation in claudin-14 increases the risk of kidney stones. The study found that alterations in the gene's activity influence stone development when calcium or salt intake is high, leading to an increase in urine calcium levels.

SourceWashU Medicine·JournalThe EMBO Journal·DateApr 18, 2012

Loyola study debunks common myth that urine is sterile

Researchers at Loyola University Chicago Stritch School of Medicine found bacteria in the bladders of some healthy women, challenging the common belief that normal urine is sterile. The study also revealed that standard urine collection methods can be contaminated by vaginal bacteria.

SourceLoyola Medicine·JournalJournal of Clinical Microbiology·DateApr 9, 2012

Clues revealed to cause of deadly kidney disease in newborns

Researchers found that small vesicles called exosome-like vesicles (ELVs) are involved in transporting signals through urine and interacting with primary cilia in the kidneys. This discovery may help understand how gene mutations cause autosomal recessive polycystic kidney disease (ARPKD), a condition that often leads to kidney failure.

SourceAmerican Society of Nephrology·JournalJournal of the American Society of Nephrology·DateOct 24, 2011

When nature calls

Researchers at Texas A&M University found that male swordtail fish strategically release pheromone-packed urine in the presence of females as a display of courtship. The study, published in PLOS ONE, challenges previous assumptions about passive pheromone release in fish.

SourceTexas A&M University·JournalPLOS ONE·DateFeb 10, 2011

Pheromone responsible for male mouse 'sex appeal'

Scientists have identified a key pheromone, darcin, responsible for male mouse 'sex appeal.' This chemical stimulates females to remember individual males and prefer them over others. By understanding the role of darcin, researchers may develop new methods for pest control and gain insights into animal behavior.

SourceUniversity of Liverpool·JournalBMC Biology·DateJun 3, 2010

Risk of death in general population independently predicted by both low kidney filtration rate and high albumin: creatinine ratio

A meta-analysis of over 1 million people found that both low kidney filtration rate (GFR) and high albumin: creatinine ratio independently predict mortality risk in the general population. Low GFRs were associated with increased risks, with those below 60 mL/min/1•73 m² experiencing a 57% increased risk of death.

SourceThe Lancet_DELETED·JournalThe Lancet·DateMay 17, 2010

Surgical options for female incontinence found to be effective but with different complications

Two surgical techniques for female stress incontinence were found to be equivalent in efficacy but differed in side effects. The retropubic procedure had a higher rate of urinary dysfunction requiring surgery compared to the transobturator procedure. These findings will help guide care for women undergoing stress-incontinence surgery.

SourceLoyola Medicine·JournalNew England Journal of Medicine·DateMay 17, 2010

Urine LAM-ELISA poor at diagnosing TB

A new diagnostic test, urine LAM-ELISA, was tested on 291 Tanzanian patients suspected of having TB and found to have a disappointing sensitivity of 50.7%. The specificity of the test was also low at 87.8%, raising concerns about its reliability as a standalone diagnostic tool.

SourceBMC (BioMed Central)·JournalBMC Infectious Diseases·DateAug 27, 2009