Articles tagged with Urine
Duke University engineers have developed a new urinary catheter design that can eliminate nearly all hard-to-kill biofilm from the catheter's walls using physical deformation. The design features an inflation channel that forces the thin wall into the urinary tract, leaving the outer dimensions intact.
A collaborative study has identified metabolomic biomarkers in urine and serum samples of women with preeclampsia, suggesting an early metabolic profile difference from women with normal pregnancies. The findings may lead to earlier detection and potentially prevent the disease.
A new noninvasive urine test can distinguish among different causes of acute kidney dysfunction in transplant recipients. The test measures messenger RNAs related to disease processes and may allow patients to avoid invasive kidney biopsies.
A simple change in urine culture reporting reduced unnecessary antibiotic prescriptions by 76% among hospitalized patients at low risk for UTIs. The study suggests that modifying how test results are reported to clinicians can improve prescribing practices and patient safety.
Handling receipts without gloves for 2 hours increases urine bisphenol A concentrations, a less-studied exposure source. Gloves offer no protection against thermal paper's heat-sensitive coating.
The FINNO Study found that women are more likely to suffer from incontinence, while men experience problems with slow or incomplete urination. The study also identified post-micturition dribble as the most common cause of bother among men.
A new assay uses recombinase polymerase amplification to detect Chlamydia trachomatis directly from urine samples, showing high sensitivity levels and specificity. The test has the potential to be applied in numerous point-of-care settings due to its simplicity and cost-effectiveness.
Researchers found no effect of low-dose dopamine or low-dose nesiritide on cumulative urine volume, kidney function, weight change, or clinical outcomes compared to placebo. The study's findings do not support the use of these drugs as a renal adjuvant therapy.
A significant link has been found between high levels of exposure to particulate matter by first responders at Ground Zero and the development of kidney damage. Albuminuria, a sign of kidney disease, was significantly higher in those with high exposure levels.
A new study from UMass Medical School reveals that human cytomegalovirus rapidly evolves as it spreads from mother to fetus, providing genetic targets for new therapeutics. The researchers found a specific window of gestation during which CMV is most vulnerable, suggesting an opportunity for preventative treatments.
A recent study published at CHEST 2013 found that smokers of long or ultralong cigarettes have higher levels of tobacco-specific carcinogens in their urine. This increased risk is associated with older smokers, non-Hispanic blacks, and females who tend to smoke these larger cigarette sizes.
Researchers found distinct bacteria in women with stress urinary incontinence (SUI) and urgency urinary incontinence (UUI), suggesting potential new treatment approaches.
Researchers at MIT have created a noninvasive diagnostic test that detects blood clots in urine, enabling early detection and treatment of life-threatening conditions such as strokes and heart attacks. The test uses nanoparticles to detect thrombin, a key factor in blood clotting, allowing for rapid screening and diagnosis.
A study found that treating asymptomatic urinary tract infections with antibiotics does not decrease the risk of bloodstream infection or mortality. Only a small percentage of patients who developed bacteria in their blood had it originating from the urinary tract.
Researchers have developed a simple and reliable urine test to detect blood clots, which can cause life-threatening conditions. The test uses synthetic biomarkers that can sense vascular diseases remotely from the urine.
Researchers at Bascom Palmer Eye Institute have discovered a key marker in blood and urine that can identify people who carry genetic mutations causing retinitis pigmentosa, a blinding disease. The test is non-invasive and easy to perform, especially for young children.
A new urine test has been developed to diagnose retinitis pigmentosa, a degenerative eye disease. The test uses mass spectrometry to analyze dolichol profiles in urine and blood samples, distinguishing between different gene mutations that cause the disease. This non-invasive test could provide personalized care for patients with RP.
Researchers found that genetic loss of a proton pump in beta-intercalated cells leads to increased prostaglandin E2 production, promoting hypokalemia and hypercalcemia. Pharmacologic inactivation also results in dRTA-like symptom development.
New research reveals that Toxoplasma infection can permanently alter brain function in mice, making them fearless of cats. The parasite's effect persists for months even after recovery from flu-like symptoms.
Researchers have identified a simple method to detect patients who hold onto excess sodium, which may lead to high blood pressure. This method involves taking a second urine sample and blood pressure measure during a doctor's visit.
A new study found that children who retained sodium in their urine were more likely to develop high blood pressure. The test can help pediatricians manage and treat hypertension in patients, providing valuable information for early intervention.
Researchers at Penn State College of Medicine have found that transplanting fat into mice with maple syrup urine disease (MSUD) significantly lowers amino acid levels, a breakthrough for treating this rare inherited disorder. The procedure may also be effective for other metabolic diseases.
Researchers at the University of Alberta have identified over 3,000 chemicals in human urine, expanding the list from just 50-100 previously known compounds. This discovery is expected to revolutionize medical testing, enabling fast, cheap, and painless tests using urine instead of blood or tissue biopsies.
Researchers tracked changes in gene expression to predict kidney damage severity in children with urinary tract obstruction. The study identified specific genes associated with the degree of obstruction, which could help identify children at risk of chronic kidney disease and permanent organ damage.
A recent study published in the Clinical Journal of the American Society of Nephrology found that individuals with type 2 diabetes and normal kidney function who have persistent albuminuria (protein in the urine) are at a greater risk for cognitive decline. The study, which followed 2977 diabetics over four to five years, showed that t...
A multidisciplinary team led by Irina Buhimschi at Nationwide Children's Hospital has been awarded a Grand Challenge grant for their low-cost, paper-based urine test to diagnose preeclampsia. The test enables early diagnosis of the condition in resource-limited areas, reducing morbidity and mortality related to preeclampsia.
Researchers developed a noninvasive protein-based urine test that accurately monitors kidney transplant risk and detects rejection before clinical signs appear. The study found low levels of CXCL9 protein can rule out rejection as a cause of kidney injury, offering a promising diagnostic tool for managing transplant patients.
The portable device, developed by UCLA researchers, can determine levels of albumin in urine and transmit results within seconds, reducing the need for frequent office visits. The device weighs around one-third of a pound and is compatible with smartphones.
Research found that the average pregnancy length is 268 days, but variations of up to 37 days were detected. Factors such as a woman's age, birth weight, and previous pregnancies also influenced gestation duration.
Stem cells found in urine have been shown to differentiate into various cell types, including bladder, bone, cartilage, and endothelial cells. These cells offer a promising alternative for autologous therapy, potentially treating urology-related conditions and other fields.
Researchers from the University of Liverpool and University of the West of England have developed a device that can detect bladder cancer through urine scent analysis. The ODOREADER device analyzes chemicals in gas emitted from urine to produce a 'profile' that can be used to diagnose cancer cells in the bladder.
A new noninvasive urine test can diagnose and predict kidney transplant rejection with high accuracy, offering an alternative to the standard kidney biopsy. The test uses biomarkers in the urine of kidney transplant recipients to detect rejection, allowing doctors to intervene early and prevent kidney injury.
Researchers have developed a non-invasive method to detect acrolein levels in people with spinal cord injuries and multiple sclerosis, offering potential relief from symptoms. The test measures N-acetyl-S-3-Hydroxypropylcysteine, a metabolite of acrolein, which is stable in urine.
A Kaiser Permanente study found that high levels of BPA in urine were associated with a double risk of obesity in girls between 9 and 12 years old. The study suggests that BPA could be a potential environmental obesogen, contributing to the worldwide obesity epidemic.
A recent study by Johns Hopkins scientists reveals an association between elevated cadmium levels and increased risk of liver disease in men. Higher levels of cadmium in urine were found to be nearly 3.5 times more likely to lead to liver-related deaths compared to lower levels.
Researchers found that anti-smoking ads with strong arguments trigger brain activity associated with behavioral change and lead to less nicotine in smokers' urine. The study suggests that ad content is more important than format or special effects for reducing tobacco intake.
A new study at Rhode Island Hospital found that many older women are overdiagnosed and overtreated for urinary tract infections (UTIs), highlighting the importance of accurate diagnosis. The study suggests that collecting urine by inserting a temporary catheter may reduce false-positive results and unnecessary antibiotic exposure.
Researchers found that premature babies with abnormal gut bacteria are at risk of necrotizing enterocolitis. The study identified specific bacteria, including Firmicutes and Enterobacteriaceae, that can be detected through a simple urine test.
Researchers at Massachusetts General Hospital successfully developed implantable, bioengineered rat kidneys that produced urine and functioned in living animals. The approach uses donor organs stripped of cells, repopulated with human or animal cells, and cultured to mimic native organ structure and function.
Researchers have identified a substance that prevents fluid accumulation and edema formation in the body, offering new hope for treating excessive fluid retention in patients with chronic heart failure. The discovery also reveals a new molecular mechanism controlling water homeostasis in the kidneys.
Researchers at ETH Zurich have developed a new method to analyze the chemical composition of exhaled breath, revealing an individual's unique 'breathprint' that stays constant over time. This non-invasive approach holds promise for early disease detection and monitoring, and could potentially replace traditional blood and urine analysis.
A new study led by Boston University School of Public Health researchers found that the chemical TDCPP was present in 99% of dust samples from participants' homes, vehicles and offices. The office environment was the strongest predictor of metabolized TDCPP in urine, with lower concentrations in newer buildings.
Researchers found that urine mercury concentrations may overestimate exposure to dental amalgam fillings, especially in populations with low occupational exposure. The study used mercury isotopes to accurately assess human exposure and provides a novel method for determining health risks.
Researchers identify semaphorin 3A as a sensitive biomarker for early detection of acute kidney injury, which can help minimize damage and potentially reverse it with rapid intervention. High levels of the protein in urine are accurate at identifying injured kidneys within two hours after cardiopulmonary bypass surgery.
A recent study published in Mayo Clinic Proceedings found that microscopic hematuria is an unreliable indicator of urinary tract malignant tumors. The study developed a Hematuria Risk Index to predict cancer risk, identifying low-risk patients who may not need further evaluation and reducing unnecessary evaluations.
A simulated Mars mission revealed rhythmic fluctuations in sodium levels with 7-day and monthly cycles, suggesting sodium storage and implications for blood pressure control. The study found that nearly all ingested salt was excreted in urine, but not daily, and that hormonal responses also fluctuated with these cycles.
Researchers found that antibiotic-resistant E. coli can survive in soil and recolonize in animal guts through pasture, forage or bedding. They propose potential solutions to limit the spread of resistance by isolating residual antibiotics before they interact with soil bacteria.
A Norwegian study found that triclosan exposure in children is associated with elevated IgE levels and rhinitis. Triclosan has been linked to an increased risk of developing allergies due to its ability to change bacterial flora on the skin, in the mouth, and in the intestines.
Scientists have developed a new micropump capable of producing pressures up to 17,000 pounds per square inch for 'labs-on-a-chip' in handheld devices. This innovation could enable instant analysis of blood and urine at patient bedside, reducing the need for central lab waiting periods.
Researchers at Queen Mary University of London discovered that the characteristic shape of a man's urine stream can be used to diagnose urinary problems, including those associated with prostate enlargement. The study found a strong correlation between the shape of the urine flow pattern and the maximum urine flow rate.
A Spanish researcher proposes using urine as a CO2 absorbent, producing ammonium bicarbonate and calcium carbonate when combined with olive waste water. The mixture can absorb various grams of CO2 per liter and reduce emissions by 1% in a stable manner.
Researchers at the University of Alberta discovered a link between sodium and calcium regulation in the body. Excessive sodium intake can lead to calcium depletion, causing thin bones and osteoporosis, while high urine calcium levels increase the risk of kidney stones.
Researchers identify molecule that sequesters copper and routes it through urine, providing a previously unknown escape route from the body. This discovery could lead to new treatments for Wilson's disease, a rare disorder that causes copper accumulation in the liver.
A study found that a simpler lifestyle with fresh foods and limited use of environmental chemicals can reduce exposure to EDCs. Researchers analyzed urine samples from OOM women and compared them to NHANES data, finding lower levels of BPA and phthalates in the former group.
Researchers at the University of Michigan Health System found that patients who receive a mid-urethral sling during prolapse repair have less than half the risk of urinary incontinence. The study suggests that inserting a sling during surgery can significantly reduce urine leakage, but also increases the risk of certain side effects.
A multicenter study found that midurethral slings significantly reduce the risk of post-surgical urinary incontinence in women without pre-existing symptoms. The study's findings provide valuable data for counseling patients and help physicians make informed decisions about sling use.
Researchers at Arizona State University and NASA have developed a new technique for detecting bone loss using isotope analysis. This method is more sensitive than current X-ray methods and poses less risk to patients, making it a promising tool for early detection of diseases such as osteoporosis.
Scientists have created a new, inexpensive paper-based urine test to monitor glucose levels in areas with limited healthcare access. The device detects glucose levels using a simple enzyme reaction and can be built quickly, making it an ideal solution for rural India and other developing countries.
Researchers found excess protein in urine dipstick tests predicted renal failure in 55% of sepsis patients. The test is widely available and inexpensive, providing early diagnosis of renal failure.
A study by Loyola Medicine found that routine urodynamics tests before stress incontinence surgery are not necessary for most patients, suggesting a potential cost savings. The study evaluated over 630 women with stress incontinence and compared those who underwent urodynamics testing to those who received only a doctor's evaluation.