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Low levels of salivary cortisol associated with aggressive behavior

A four-year study found that consistently low salivary cortisol levels in boys aged 7-12 are associated with early onset and persistence of aggressive behavior. Boys with low cortisol levels exhibited three times the number of aggressive symptoms and were more likely to be singled out by their classmates.

SourceUniversity of Chicago Medical Center·JournalArchives of General Psychiatry·DateJan 13, 2000
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Recent research suggests new strategy for treating depression

Recent studies have found that high cortisol levels might be a cause of depression, potentially leading to new antidepressant drug strategies. Cortisol-lowering drugs have shown promise in reducing depressive symptoms, especially in patients with high cortisol levels.

SourceUniversity of California - San Francisco·JournalPsychosomatic Medicine·DateSep 27, 1999

High stress hormone levels impair memory

Researchers at WashU Medicine found that high doses of cortisol, produced in response to stress, can significantly impair memory performance after several days. Memory impairment was seen only in those who received a high dose of cortisol and only after four days of treatment.

SourceWashU Medicine·JournalArchives of General Psychiatry·DateJun 15, 1999

Some CFS Patients Benefit From Low-Dose Steroid, But Side Effects Too Risky

A low-dose hydrocortisone study found slight improvement in some chronic fatigue syndrome (CFS) symptoms for about half the participants, while two-thirds on hydrocortisone reported better well-being. However, the treatment also induced adrenal suppression in twelve patients, rendering it an unsuitable option for CFS patients.

SourceNIH/National Institute of Allergy and Infectious Diseases·JournalJAMA·DateSep 22, 1998

Antifungal Drug May Be New Treatment For Chronic Kidney Disease

Researchers found that ketoconazole slowed disease progression by 66% in patients with glomerular disease and 77% in those with diabetic nephropathy. However, the treatment accelerated disease rate in patients with polycystic kidney disease. Further studies are needed to confirm these findings.

SourceJohns Hopkins Medicine·DateApr 1, 1997
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