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A standard operation procedure to effectively detect dietetically absorbed plant miRNAs

Researchers at Nanjing University have developed a standard operation procedure to detect dietetically absorbed plant miRNAs in human plasma. The study identified six plant miRNAs with dynamic physiological patterns and kinetic absorption curves, suggesting they can exert physiological functions.

SourceNanjing University School of Life Sciences·JournalThe Journal of Nutritional Biochemistry·DateFeb 21, 2015

A new look at proteins in living cells

A new method, SPR microscopy, allows for quantitative analysis of protein interactions on cell surfaces, streamlining drug development and diagnostic biomarker identification. The technique provides high-resolution spatial and temporal information, revealing dynamic processes evolving over time.

SourceArizona State University·JournalNature Nanotechnology·DateAug 27, 2012

Lab on chip for membrane proteins

A novel lab-on-chip device has been developed to screen sensitive membrane proteins in parallel, utilizing a nano-fabricated chip with 50,000 nanopores. This technology preserves protein structure without organic solvents or solid support, enabling simultaneous analysis and preserving fragile protein function.

SourceGoethe University Frankfurt·JournalNano Letters·DateNov 9, 2010

Kinetic variable most useful for identifying malignant MRI-detected breast lesions identified

Researchers found that the 'washout' curve type is most predictive of malignancy, with 45.7% of lesions with this pattern being malignant compared to 20% with a plateau and 13.3% with persistent enhancement. The study suggests that kinetic features in breast MRI assessment can help determine whether a lesion needs biopsying.

SourceAmerican College of Radiology·JournalAmerican Journal of Roentgenology·DateAug 19, 2009

A walk along an interface yields its mobility

Researchers at Colorado School of Mines and Northeastern University report a new computational methodology to quantify interface mobility, overcoming limitations of past studies. The method efficiently addresses the effect of impurities, revealing a more severe impact on interface motion than previously thought.

SourceNortheastern University·JournalScience·DateNov 2, 2006