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UNC scientists solve mystery of how largest cellular motor protein powers movement

Researchers have discovered a flexible coiled-coil region in dynein that enables rapid conversion of chemical energy into mechanical force, powering cell division and mitochondrial transport. This breakthrough sheds light on the protein's function and may hold implications for understanding neurodegenerative disorders.

SourceUniversity of North Carolina Health Care·JournalProceedings of the National Academy of Sciences·DateNov 27, 2006