Articles tagged with Cohort Studies
A new study from the University of Eastern Finland found that people with Alzheimer's disease (AD) had a higher risk of mortality in procedural units and during follow-up, compared to those without AD. However, elective revascularisation procedures showed similar outcomes for both groups.
A Mediterranean-style diet rich in green leafy vegetables and low in meat is associated with higher scores on memory and thinking tests among adults in their late 70s. However, the study found no link between the diet and better brain health or markers of healthy ageing.
A new study published in PLOS Medicine found that whole egg consumption was positively associated with increased all-cause mortality, while egg whites or substitutes were negatively associated. Replacing half a whole egg with egg whites/substitutes reduced cardiovascular disease mortality by 3%.
A new study suggests that starting adulthood with a normal weight and gradually gaining pounds later in life can increase the probability of survival. In contrast, those who start as obese or stay at an unhealthy weight throughout their lives tend to have the lowest survival rates.
A recent study published in Microplastics and Nanoplastics journal concludes that marine litter in coastal systems has remained constant since 2019, with some components showing a decrease. The steady state scenario raises questions about the transfer of plastic litter to remote areas or degradation into smaller fragments.
A Swedish study found COVID-19 intensive care mortality rates were lower compared to other countries, despite higher comorbidities. The study suggests process and organisational factors contributed to the better outcomes.
A systematic review and meta-analysis of 20 studies found that self- and caregiver swabs are effective at detecting multiple pathogens, with high sensitivity (91%) and specificity (98%) compared to healthcare worker-collected swabs. This approach offers advantages in reducing transmission risk, expenses, and discomfort for patients.
Research found no statistically significant difference in concussion recovery time between males and females, but subtle differences were seen in contact and limited contact sports, suggesting differential access to athletic training and medical resources may be contributing factors
A new study from the University of Notre Dame finds that people tend to overestimate their financial responsibility, resulting in under-saving. The research developed an intervention to combat this 'positive illusion' by recognizing excessive spending and boosting self-perceptions of financial responsibility through increased savings.
A retrospective cohort study of 251 primary care physicians found significant variation in medical practice patterns across different doctors, but relatively stable patterns within an individual's practice over time. Researchers propose that personal behavioral characteristics may explain these variations.
A national study found significant sex and age-based differences in nonfatal opioid overdoses among youth, with female youth between 11-16 having a higher incidence. The study highlights specific risk factors that could inform targeted interventions to prevent opioid overdoses in adolescents and young adults.
A large cohort study found that dog owners with diabetes are 38% more likely to develop type 2 diabetes than those without. In contrast, no shared risk was detected in cat owners and their cats.
A large study of 6,510 healthcare workers found that community exposure was the main driver of COVID-19 infections. Nurses were at higher risk once community exposure was accounted for, while high-flow oxygen therapy and hemodialysis increased antibody production to SARS-CoV-2.
A large-scale study found that genetics contribute to most cases of extremely large or small birth weights in full-term babies. However, the role of genetics was less significant in the smallest three per cent of babies, suggesting other factors such as placental health may be involved.
The study has achieved encouraging participation rates with 556 participants agreeing to share their data. Preliminary findings indicate that most enrolled individuals experienced mild symptoms, with common comorbidities including smoking, asthma, and obesity.
A study published in BMC Medicine found that vegans had a 43% higher risk of total fractures compared to meat-eaters, with higher risks of hip, leg, and vertebrae fractures. Vegetarians also had a higher risk of hip fractures.
A study published in Occupational & Environmental Medicine found that newly retired women experience a sharp rise in sedentary time, which persists 2+ years later. The research suggests that prolonged sitting is more harmful than short bouts and may be linked to social isolation and decreased physical activity after retirement.
USC researchers warn that COVID-19 could cause developmental difficulties and accelerated aging in the century ahead due to in-utero exposure. The study suggests that prenatal exposure to SARS-CoV-2 may have long-term impacts on childhood development and adult health.
A UT Southwestern study found that retired football players with a history of concussions and mild cognitive impairment (MCI) scored similarly to non-athletes on verbal memory and learning tests. However, they showed lower scores on naming tests, which may be related to age-related decline rather than concussion effects.
Research highlights the need for tuberculosis (TB) screening and ongoing clinical care for people on methotrexate living in areas with high TB prevalence. Methotrexate users taking corticosteroids or immunosuppressants are at increased risk of TB infection.
A recent study found that young Finnish athletes experience higher rates of menstrual dysfunction compared to non-athletes. However, athletes reported lower levels of body weight dissatisfaction. The study suggests that low energy availability may contribute to menstrual dysfunction in young athletes.
The study found associations between specific single nucleotide polymorphisms (SNPs) and clinical features of follicular lymphoma, including tumor microenvironment composition. The researchers identified key immune-related genes associated with worse survival outcomes in patients treated with rituximab-containing regimens.
A researcher created a computer model that can distinguish high academic achievers from lower ones based on their social media posts. The model achieved an accuracy of 93.7% in predicting PISA scores, indicating students' academic aptitude.
A University of Michigan study found that nearly one-third of students who reported misusing prescription opioids as high school seniors later used heroin by age 35. The research also showed a significant increase in heroin use among individuals with a history of prescription opioid misuse, contributing to the opioid epidemic.
Research shows that high-status individuals can face biases in award decisions when judged publicly, but benefits from close social ties to judges in private settings. The study emphasizes the need for accountability and transparency in decision-making processes.
A nationwide cohort study has confirmed that non-alcoholic fatty liver disease (NAFLD) is associated with increased mortality risk, even in mild stages. The study found that patients with NAFLD had a 93% increased risk of all-cause mortality, driven primarily by deaths from extra-hepatic cancer and cirrhosis.
Adults with depression who initiated newer antipsychotic medication showed a 45% increased mortality risk compared to those using a second antidepressant. The study suggests careful consideration of antipsychotic treatment for depression, as the benefits are modest and the risks substantial.
A new study by the RAND Corporation found that American adults have increased their alcohol consumption significantly during the pandemic, with women experiencing a 41% rise in heavy drinking episodes. The overall frequency of alcohol consumption also rose among all adults aged 30 and above.
A study by University of Jyväskylä found that older adults (75-80 years) have improved muscle strength, walking speed, reaction time, verbal fluency, and cognitive performance compared to the same-aged individuals in the 1990s. Increased education was a key factor behind these improvements.
A study of over 6,500 US adults found a link between COVID-19-related symptoms and preexisting conditions, job loss, and excessive media consumption. Acute stress and depression symptoms were more closely tied to personal exposure to the virus than community-level exposure.
A recent study found that being physically active can significantly reduce the risk of developing chronic kidney disease (CKD). The study, which followed over 15,000 middle-aged adults for 24 years, showed that even moderate physical activity can lower the risk of CKD by up to 11%.
A machine learning system has been developed that can predict the development of Bipolar Disorder up to 4 years before onset in young people. The system identified risk factors such as suicidal tendencies and financial problems, allowing doctors to take preventative measures.
Researchers at UC Berkeley found a correlation between poor sleep quality and increased beta-amyloid plaques in the brain, indicating an earlier onset of Alzheimer's disease. Deep non-REM slow-wave sleep has been identified as a potential target for intervention against cognitive decline.
A study from Aarhus University found that relatives with severe long-term grief reactions have more frequent GP contact and higher medication use before bereavement. This suggests that early intervention may help prevent severe grief reactions.
A cardiac biomarker was found to have stronger associations with kidney disease progression than blood pressure in both diabetic and nondiabetic individuals. Higher levels of NTproBNP, urine NGAL, and troponin T were linked to increased rates of CKD progression.
A recent study revealed that the human gut microbiome is linked to multiple diseases and traits, including chronic obstructive pulmonary disease, atopy, and BMI. The research used genetic data to estimate microbiome composition in a large cohort of unrelated individuals, finding associations between eleven bacteria and 28 health outcomes.
A new study found that members of Generation X, who came of age during the 1980s and early 1990s, have higher rates of incarceration throughout their lives. This is due to extended criminal history under a determinate sentencing regime implemented in 1994.
A group of international scientists has developed a new definition for synbiotics, outlining a mixture of live microorganisms and selectively utilized substrates that confer a health benefit on the host. The definition aims to clarify scientific ambiguity and provide a foundation for science-based claims about synbiotic health benefits.
A study of Finnish parents reveals a link between vaccine scepticism, low trust in medical doctors, and defiance. The research also found that individuals who defy rules and recommendations are more likely to use alternative medicine.
Elevated NT-proBNP levels are associated with a reduced risk of developing type 2 diabetes, especially in women. However, those who develop diabetes with elevated NT-proBNP have a higher risk of macro- and microvascular complications such as heart attack, stroke, or severe damage to eyes, kidneys, or nerves.
A new study found that vitamin D supplementation is associated with a decrease in Megamonas bacteria and C. difficile colonization in infants, suggesting potential benefits for childhood health.
A new study in the Journal of Marketing identifies cultural variable power distance belief as a determinant of consumers' price sensitivity. Consumers high in power distance belief are less price-sensitive and more likely to seize current offers, reducing their likelihood of searching for better-priced options.
Research published in the American Journal of Obstetrics and Gynecology found that women who consume alcohol during early pregnancy face a higher risk of miscarriage. The study analyzed data from over 5,500 women and found an incremental 8% increase in miscarriage risk each week of alcohol use.
A large international study identified key genetic contributors to stroke risk in individuals of African ancestry, providing insight into ethnic-specific and global risk factors. The study found that a common variation near the HNF1A gene was strongly associated with increased stroke risk.
Researchers analyzed data from the Framingham Osteoporosis Study to explain the decline in hip fracture rates in the US. Lifestyle factors such as reduced smoking and excessive alcohol consumption contributed to the decrease, highlighting the importance of public health interventions.
Researchers found no Candida auris acquisition in healthy US international travelers returning from international trips, suggesting low risk of transmission during travel. The study's results could lead to developing a detection system for high-risk populations.
A new Boston University School of Public Health and School of Medicine study finds that genetic risk factors for dementia can be lowered by improving cardiovascular health. Participants with a high genetic risk score were 2.6 times more likely to develop dementia, but those with good cardiovascular health were half as likely.
The CHASING COVID study follows a diverse cohort of thousands of adults to understand the effects of COVID-19 on mental health, employment, and economic outcomes. The study aims to inform the response to the pandemic and future pandemics with knowledge generated from its longitudinal epidemiologic design.
A new UCL-led study reveals that people in their 40s and 50s are likely to suffer more years of ill health than older generations. The study found a greater prevalence of ill health among those born later, with conditions such as diabetes and obesity affecting people earlier.
Researchers have identified a new biomarker, asymmetric dimethylarginine (ADMA), associated with cognitive decline in old age. The study found that ADMA levels were linked to decline in cognitive performance assessments after four years.
A new study found that women with higher manganese levels in early pregnancy had a lower risk of developing preeclampsia later on. The researchers analyzed data from over 1,300 women and found an association between higher manganese levels and reduced preeclampsia risk.
Researchers found that certain gut bacteria not following a day-night rhythm can serve as an indicator for potential type 2 diabetes. Mathematical models also suggest this microbial risk signature helps in diagnosing diabetes, improving diagnosis and outlook of the disease.
Researchers found that symptoms like nausea and vomiting can occur at any time of day, not just morning. A significant number of women experience these symptoms throughout the waking day.
A KKH-led study evaluates a novel clinical protocol to screen and triage women with threatened miscarriages, saving pregnancies and reducing progestogen use. The protocol uses a single serum progesterone test to guide clinicians in managing patients.
A recent study by the University of Texas M. D. Anderson Cancer Center found that greater inactivity is independently associated with a higher risk of dying from cancer. Replacing sedentary time with physical activity, such as 30 minutes of cycling or walking, can lower this risk.
Researchers discovered a link between small airways and increased COPD risk in non-smokers. People with smaller airways relative to their lungs may have lower breathing capacity, making them more susceptible to COPD.
A new study in Frontiers in Immunology found that treatment with interferon (IFN)-α2b significantly reduced the duration of detectable virus in upper respiratory tract and blood levels of inflammatory proteins IL-6 and CRP, suggesting potential for an effective antiviral intervention
A new lung cancer screening cohort study demonstrates low adverse event rates and detects 70% of diagnosed cases at early stages. Family medicine plays a critical role in expanding lung cancer screenings to underserved populations.
A new study found that middle-aged adults reported more daily stress and lower well-being in the 2010s compared to the 1990s. The researchers attribute this increase to the added responsibilities of childcare, eldercare, and work, as well as the pace of technological advances.
A new study by Boston University School of Public Health found detectable levels of DDT and other banned organochlorine pesticides in the blood of over 60% of Detroit-area black women. The chemicals were linked to tobacco, alcohol, and water consumption, posing hormonal and metabolic issues.