Articles tagged with Cohort Studies
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A study in CMAJ investigated whether HPV vaccination triggers autoimmune conditions like lupus and rheumatoid arthritis. The research analyzed data from 290,939 girls aged 12-17 who received the HPV4 vaccine between 2007 and 2013, finding no increased risk of autoimmune disorders.
A study published by The Endocrine Society found that couples who eat more seafood tend to get pregnant faster. Seafood consumption was associated with a higher frequency of sexual activity and shorter time to pregnancy, suggesting other biological factors may be at play.
Researchers at MD Anderson Cancer Center found that intense post-treatment surveillance does not improve detection of recurrence or overall survival in stage I, II, or III colorectal cancer. The study suggests that current guideline recommendations need to be reconsidered.
Patients with inflammatory bowel disease (IBD) are at a 22% higher risk of developing Parkinson's disease compared to non-IBD individuals. Researchers found this association independent of age, gender, and length of follow-up.
A feasibility study suggests that airway transplantation using cryopreserved aortic grafts may be an effective treatment option for patients with lung cancer and end-stage tracheobronchial disease. The study shows promising results, including low mortality rates and successful breathing through newly formed airways.
A study published in The Spine Journal found that one-third of people aged 40-59 have image-based evidence of moderate to severe degenerative disc disease. Additionally, the prevalence of spinal osteoarthritis increased significantly with age, particularly among women.
A new study found a consistent link between maternal grandmother and grandchild abdominal obesity, suggesting an intrauterine or environmental effect. The association was seen in both time points analyzed, from age 5 to 9 years old.
A new study published in Diabetes Care found that lesbian and bisexual women have a significantly higher risk of developing type 2 diabetes, with a 27% higher incidence than heterosexual women. The study also found that stress related to discrimination and violence victimization may contribute to these disparities.
A large European study links biological dusts, gases, and fumes to a significantly increased risk of Chronic Obstructive Pulmonary Disease (COPD). The research found that exposure to certain occupational agents can increase the incidence of COPD by up to 120%.
New research suggests that poor countries will experience significant increases in temperature variability due to climate change. The study found that up to 15% more extreme temperature fluctuations are predicted for southern Africa and Amazonia, highlighting the unfair pattern of climate impacts on vulnerable populations.
A new study finds that individuals with chronic kidney disease who slept 7 hours/day had higher health-related quality of life compared to those who slept 5 or 9 hours/day. Sleep disorders are common among CKD patients, leading to fatigue, lack of energy, and drowsiness.
A study by University of Turku researchers found that retirement transition leads to a significant increase in sitting during free time, averaging six hours per day. This increase was especially noted among women and individuals with pre-existing health conditions.
A study found that consumers tend to blame companies for imposing internal and external surcharges, even if the charges were imposed by an outside agency. The characteristics of the surcharge can shift blame, with customers being more likely to blame the firm if it's something internal.
A new study found that Republicans are more persuasive than scientists in correcting misinformation about climate change, despite being associated with denial. The researchers suggest that citing Republican elites endorsing the scientific consensus may be an effective way to persuade citizens.
A study found that patients with a treating pivot nurse had higher patient satisfaction scores and better quality-of-life outcomes compared to those without such support. The coordinated care improved patients' understanding of their disease, treatment side-effects, and overall strength in fighting cancer.
A recent study found that major disruptive events, such as clinician losses and changes in ownership, frequently disrupt primary care practices in Oklahoma. These events negatively affect quality improvement efforts and patient care, highlighting the need for further research to address their root causes.
Chronic sleep deprivation increases risk of motor vehicle crashes due to impaired cognitive function. The study found severe sleep apnea is associated with a 123% increased risk, while mild to moderate sleep apnea elevates the risk by 13%. Short sleep duration also contributes to crash risks.
A study published in the Journal of Pediatrics found that an expert panel of pediatric injury experts can reliably identify injuries in young children as abuse or accidents. The panel achieved nearly perfect reliability and accuracy, both individually and collectively.
Research suggests individuals who undergo bariatric surgery are more likely to find a new partner or get married compared to non-operated control subjects. However, separations and divorces may also increase slightly after surgery due to lifestyle changes.
A study by Indiana University found that 93% of pregnant women had detectable levels of glyphosate in their urine, correlating with shortened pregnancy lengths. Glyphosate exposure is suspected to be primarily through dietary intake of genetically modified food items and caffeinated beverages.
Aarhus University's study found that 9% of participants in a health check were psychologically vulnerable and lacked assistance from medical doctors or psychologists. The study suggests that including mental health assessments in health checks can help identify those in need, enabling targeted support and prevention.
A recent study published in the Journal of Clinical Lipidology found that omega-3 levels were better predictors of death risk than serum cholesterol. The study showed a 33% reduction in mortality risk among participants with highest omega-3 blood levels, indicating a potential marker for overall health.
Researchers found that African Americans with a common genetic variation are 30% more likely to develop Alzheimer's disease dementia. In contrast, European Americans without the polymorphism are not at increased risk. Further studies are needed to understand why this correlation only appears in African-Americans.
Experts on quantum computing, including Antia Lamas-Linares, discussed the field's potential and applications at SXSW 2018. They focused on topics such as secure time synchronization and GPS protection, highlighting the importance of these areas in the future development of quantum technologies.
A joint 7-year cohort study of 2039 patients in Singapore and New Zealand found that heart failure patients with preserved ejection fraction (HFpEF) have better survival rates and outcomes compared to those with reduced ejection fraction (HFrEF). The study provides greater accuracy about the risk of dying from heart failure.
A new study published in BMJ Open reveals that people over 85 are more likely to consult their GP for medical needs, highlighting the need for specialist geriatric colleagues to support primary care services. The study's findings suggest a growing concern over the impact of an ageing population on the NHS.
A study published in CMAJ found that older age at immigration and emigration from regions with high TB incidence increase the risk of TB in Canada. Latent TB screening and treatment are suggested as practical solutions to reduce TB incidence in these high-risk groups.
A recent study on hospital palliative care reveals high rates of caregiver depression and significant moral distress among resident physicians. The research also explores the challenges faced by LGBT individuals who have lost a partner, including homophobia and additional legal and financial issues. Effective interventions, such as adv...
A Finnish study found that individuals with diabetes experienced fewer work-loss years than those without the condition. Those who retired early also worked an average of two years longer due to their diabetes diagnosis.
A study published in Thorax found that leisure-time vigorous physical activity is associated with better lung function among current smokers. Regular physical activity was shown to improve respiratory muscle endurance and strength, leading to higher lung function.
A large Finnish cohort study found that the risk of death by suicide among hospitalized patients with depression has decreased by half since 1991. The study tracked 56,826 patients and attributed the decline to various factors, including improved treatment for depression and increased access to psychotherapy.
A national register study by the University of Turku and THL found that more adolescents are receiving psychiatric or neurodevelopmental diagnoses, especially girls, between ages 12 and 18. The diagnoses primarily relate to depression and anxiety, with limited psychotherapy treatment options available.
A diet high in inflammatory foods like meats, refined grains, and sugary drinks is associated with a higher risk of developing colorectal cancer. Higher scores on the inflammatory potential index were linked to an increased risk in both men and women.
A retrospective cohort study found that bariatric surgery is associated with a lower risk of death from any cause compared to nonsurgical obesity management. The study analyzed data from over 8,000 patients who underwent weight-loss surgery and 25,000 who received nonsurgical care.
The study reveals a statistically significant increase in overall and casino gambling participation among Massachusetts residents. Notably, only 49.4% of individuals who were problem or pathological gamblers in Wave 1 remained in this category in Wave 2, with many transitioning to recreational or at-risk gambling categories.
A large Israeli study found that mothers who took folic acid and multivitamin supplements before and during pregnancy had a lower likelihood of having children with autism spectrum disorder. However, the researchers note that other factors may explain this association.
A new study finds that hysterectomies with ovarian conservation increase the risk of hyperlipidemia, hypertension, and cardiovascular disease. Women under 35 are at greatest risk for congestive heart failure and coronary artery disease.
Adolescents who used electronic cigarettes, hookahs, noncigarette combustible tobacco or smokeless tobacco were more likely to start smoking conventional cigarettes within a year. Any use of all forms of noncigarette tobacco was associated with a greater risk of future conventional cigarette smoking.
A national survey found that 20% of Black patients and 17% of White patients reported experiencing health care discrimination. Socio-economic status interacted with reported discrimination differently for Whites and Blacks.
A Canadian study found that children who regularly eat meals with their family experience long-term physical and mental health benefits. Family meals are associated with better fitness, lower soft-drink consumption, and improved social skills.
A Drexel University study suggests that if a quarter of high-risk men use daily PrEP, 3 out of every 10 HIV infections could be prevented. The study also found that when all preventive strategies were combined, they resulted in the prevention of 72.2% of infections.
A five-week exercise program based on Zumba Fitness improved the quality of life of inactive university workers, especially their emotional well-being. The benefits persisted for up to two months after the program ended.
The full results from the second Phase 3 clinical study of LMTX confirm its efficacy as a monotherapy for mild to moderate Alzheimer's disease. The study showed significant slowing of brain atrophy and functional decline in patients treated with LMTX, while those receiving add-on therapy experienced no significant change.
Babies exposed to antibiotics for GBS developmentally delayed gut bacteria, which recovered by 12 weeks of age. Long-term effects on infant health are unclear.
A large cohort study found that patients with low-level viremia are at increased risk of treatment failure and developing virological failure. Clinical interventions should take place at lower viral loads than current WHO guidelines to prevent poor outcomes.
A new study published in International Journal of Geriatric Psychiatry found that benzodiazepine use is associated with a 40% increased risk of death among persons with Alzheimer's disease. The study, which included over 10,380 participants, suggests that these drugs may contribute to adverse events such as falls, pneumonia, and stroke.
General practitioners trained in compression ultrasonography achieve excellent accuracy in diagnosing deep vein thrombosis, with a diagnostic accuracy of 96%. The technique's sensitivity and specificity rates are comparable to those of expert physicians.
A UK study found that older patients experiencing more discontinuity of care in general practice are at a higher risk of emergency hospital admissions. Patients with the least continuity had a risk of admission twice as high as those with complete continuity.
A recent study published in HeartRhythm found that blacks have a lower risk of atrial fibrillation compared to whites, despite having similar risk factors. The research suggests that the frequency of early beats in the atria, known as premature atrial contractions, may be heritable and explain the racial differences in AF rates.
A study of over 74,000 women found that cataract surgery was associated with a 60% reduced risk of death from all causes. The researchers also noted significant reductions in deaths due to pulmonary, accidental, infectious, neurologic and vascular diseases, and cancer.
Human exposure to glyphosate has increased significantly since the introduction of genetically modified crops, with 70% of study participants having detectable levels by 2016. Glyphosate use has also increased 15-fold since 1994.
A new study suggests that walking, even at lower-than-recommended levels, is associated with a lower mortality risk compared to inactivity. Regular walking was most strongly linked to reduced risk of respiratory disease and cardiovascular disease mortality.
A new study suggests that physically active white men are at a higher risk of developing plaque buildup in their heart arteries by middle age. The study found that those who exercised the most were 27% more likely to develop this condition, compared to those who exercised less.
A new study published in Sustainable and Resilient Infrastructure predicts that warmer oceans will lead to higher wind speeds and larger storms, resulting in increased damage and financial losses due to hurricanes. The study estimates a 70% increase in hurricane-related financial loss by 2100 for coastal communities in South Carolina.
Indiana University will establish a network of sites to study early-onset Alzheimer's disease, a rare variant that affects people under 65. The Longitudinal Early-onset AD Study (LEADS) aims to bridge the gap in clinical trials for this population by collecting robust longitudinal data on genetic risk factors and treatment options.
Wayne State University will analyze 20 years of fetal alcohol spectrum disorders data to refine the new diagnosis and provide support for official recognition in the DSM. The study aims to identify key developmental outcomes, prenatal alcohol exposure levels, and critical dose effects.
A recent study published in The Journal of Nutrition found that adolescents consuming the least amount of vitamin K1 were at a higher risk for unhealthy enlargement of their heart's major pumping chamber. This association was independent of other factors such as physical activity and blood pressure.
A study by Anna Kirstine Winthereik shows that general practitioners who prioritize home visits reduce the time terminally ill cancer patients spend in hospitals and increase the likelihood of them dying at home. The study also highlights a positive correlation between frequent home visits and reduced hospital bed days.
A new study found that smoking at the time of diagnosis and changes in smoking within five years after diagnosis are associated with long-term breast cancer mortality. Quitting smoking after diagnosis may improve survival among women with breast cancer, but continued smoking increases risk of death.
A recent study published in Paediatric and Perinatal Epidemiology found that the HPV vaccine is associated with improved fertility in some women, particularly those with a history of sexually transmitted infections. The research, led by Boston University School of Public Health, suggests that vaccinated women with an STI history have s...