Articles tagged with Cohort Studies
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
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Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
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Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A new study found that adults who sit for one to two hours without moving have a higher mortality rate than those with shorter bouts of sedentary time. Breaking up long sitting periods into shorter intervals can help reduce death risk, according to researchers.
A new Australian study reveals hip fractures are a major public health issue with high morbidity and mortality rates. The research found that individuals with hip fractures were 3.5 times more likely to die within 12 months compared to non-injured counterparts, with excess mortality risk higher in males than females.
Researchers found that high levels of suPAR are a reliable predictor of kidney damage in children, similar to adults. The protein is associated with increased risk of kidney loss and progression in children with mild to moderate kidney disease.
A study published in the American Journal of Clinical Nutrition found that consuming protein throughout the day, rather than just at two meals, can lead to greater muscle mass and strength in older adults. Researchers analyzed data from over 1,800 seniors in Quebec and discovered a positive correlation between balanced protein intake a...
A new study analyzing data from the Swedish Coronary Angiography and Angioplasty Registry found no significant benefits of pre-hospital antiplatelet therapy in STEMI patients. The study suggests that pre-treatment may even pose a risk, particularly for patients with contraindications to antithrombotic therapy.
The HCM-EVIDENCE study validates ESC recommendations for predicting and preventing sudden cardiac death in patients with hypertrophic cardiomyopathy. The risk prediction tool, HCM Risk-SCD, accurately distinguishes between high- and low-risk patients, with good agreement between predicted and actual SCD rates.
A new study found that higher coffee consumption is associated with a lower risk of death, particularly among those aged 45 and above. Drinking four cups of coffee per day was linked to a 64% reduced risk of all-cause mortality.
A new study published in the European Society of Cardiology found that high salt intake is associated with a doubled risk of heart failure. The study, which followed over 4,000 participants for 12 years, estimated individual salt intake using a 24-hour sodium extraction method.
A recent study published in the Journal of the American Geriatrics Society found no correlation between thoracic kyphosis and physical function decline in those over 50. The study used CT scans to evaluate early signs of hyperkyphosis in a relatively young population, contradicting previous assumptions about its predictive value.
Long-term use of high-dose vitamin B6 and B12 supplements is associated with a two- to four-fold increased lung cancer risk in men. Male smokers taking these supplements were three times more likely to develop lung cancer, while those taking higher doses were approximately four times more likely.
Research links elemental sulfur use to poorer respiratory health in children living near farms that apply the pesticide, with significant associations found between sulfur use and asthma-related symptoms. The study suggests urgent need for more research and possible changes to regulations and application methods.
A recent study published in JAMA found that many studies supporting changes to high-risk medical devices are poorly designed and lack rigor. The researchers analyzed 83 supplement approvals for these devices and found similar problems with data quality and analysis procedures as seen in premarket approval studies.
Clinical studies supporting FDA approval of high-risk medical device modifications were found to be methodologically poor, with many lacking randomization and blinding.
A new study from McMaster University highlights the importance of public health messaging to South Asian women who are considering pregnancy. The research found that a healthy diet and pre-pregnancy weight can significantly decrease gestational diabetes risk, with approximately one-third of cases preventable.
Researchers studied health effects of job transition on employed vs unemployed adults, finding that poor quality work was linked to higher chronic stress biomarkers and worse physical health. Good quality work, however, was associated with improved mental health scores.
A new study found that dog walking increases physical activity levels in older adults, even on cold and wet days. Dog owners were sedentary for 30 minutes less per day, on average.
A new study by Harvard T.H. Chan School of Public Health finds that cumulative weight gain over the course of early and middle adulthood may increase health risks later in life, including a higher risk of type 2 diabetes, hypertension, cardiovascular disease, and premature death. The study suggests that even moderate weight gain can ha...
A study led by Queen Mary University of London predicts organ failure in critically injured patients based on the early immune response to trauma. The research identified specific genes involved in the immediate response, which may help determine which patients are at risk of developing Multiple Organ Dysfunction Syndrome (MODS).
Patients with opioid use disorder on buprenorphine are at significantly higher risk of death when in and out of treatment. The study found a 2.6 times increased risk of mortality compared to individuals without addiction issues during the same time period.
A Sam Houston State University study found that half of witnesses did not select anyone from the lineup, with 78% accuracy when a selection was made. The results show challenges in identifying suspects, particularly for witnesses of different races or ethnicities and those exposed to guns.
A UCSF-led study found that crowdsourced data may not be representative of certain populations, such as older adults and racial/ethnic minorities. The study suggests that proactive efforts are needed to promote inclusion of underrepresented groups in projects using crowdsourced recruitment and data collection.
A recent study published in the SiRENE project found that transportation noise exposure is associated with an increased risk of cardiovascular diseases and diabetes. Road noise was particularly critical, increasing the risk of myocardial infarction by 4% per 10 decibel increase. Noise also disrupts sleep patterns, which can negatively ...
A large-scale study of women carrying faults in cancer genes found that family history, gene position, and precise mutation type impact cancer risk. Estimates provide more confidence for counselling and clinical management.
A 10-year Vanderbilt University Medical Center study disputes the long-held notion that uterine fibroids increase the risk of miscarriage. Contrary to previous research, women with fibroids have an identical risk of miscarriage as those without them when accounting for other pregnancy loss factors.
A recent analysis found that individuals with debilitating pain had a higher risk of dying during the study. Those with severe pain interference reported significantly increased risks of mortality.
A nationwide study in Sweden found that specific antipsychotic agents and routes of administration impact the risk of rehospitalization and treatment failure among patients with schizophrenia. The research highlights the need for personalized treatment approaches to optimize patient outcomes.
A Danish nationwide population-based cohort study found mortality increases by 60-80% after 8-10 years post-heart bypass surgery. The study showed that the prognosis for patients who undergo successful surgery is similar to that of the general population until this point.
A new study from McMaster University found that ethnicity and breastfeeding practices independently affect the gut microbiota in infants as young as one year old. The research revealed a higher abundance of lactic acid bacteria in South Asians and Clostridia in white Caucasians, suggesting potential links to future health issues such a...
Researchers found that higher body mass index (BMI) can cause worse cardiovascular health in young adults as young as 17, according to a study using data from the Avon Longitudinal Study of Parents and Children. The study suggests that tackling obesity from an early age may help prevent cardiovascular changes that are precursors to car...
Researchers found that statin users had improved left ventricular mass and volume, and reduced thickened heart muscle and large heart chambers. This suggests that statins may lower the risk of future heart attacks, heart failure, or stroke by reversing negative changes in the heart.
Two large US studies found a significant association between high fiber intake and reduced risk of symptomatic knee osteoarthritis. High cereal fiber intake was also linked to lower worsening knee pain.
A recent research review found that moderate drinking has little support for preventing heart disease. In fact, seniors who drink moderately may be healthier due to their age and health status. However, the association between moderate drinking and better health may be misleading due to factors such as age and overall health.
Replacing one serving of sugar-sweetened soft drink or beer with a glass of water daily can lower the incidence of obesity. Drinking water instead of beer was found to reduce obesity risk by 20%, while substituting other sugary drinks showed no significant effect.
A new study by Johns Hopkins University found that once-formidable disparities between black and white families living in subsidized housing have largely vanished. Black and white children who grew up in such housing fared similarly in education, employment, and earnings.
A study found that retirement lowers biological stress levels in higher-status jobs, but increases them in lower-status jobs. This widening of the socio-economic-health gradient could contribute to rising health inequalities in old age.
Researchers found that phthalate exposure during pregnancy and breastfeeding can lead to epigenetic modifications in children, increasing the risk of developing allergic asthma. The study also showed that the effects are not limited to the child, as the offspring of exposed mothers continued to be affected even after birth.
A recent analysis of data from a critical epidemiological study found no association between formaldehyde exposure and acute myeloid leukemia. The study's findings contradict previous studies that reported associations between formaldehyde exposure and certain types of leukemia.
A large Danish cohort study found that antibiotic use is associated with lower enterolignan concentrations in the blood, especially for women. The study suggests that antibiotics can negatively affect intestinal bacteria's ability to metabolize plant lignans into enterolignans.
Researchers discovered rare genetic variants on chromosomes 4 and 7 linked to extended survival and lower risks of cardiovascular disease and Alzheimer's. The study highlights the importance of studying rare cases to identify combinations of common and rare variants associated with extreme longevity.
Research found that drinking at least one artificially sweetened beverage a day increased the risk of developing ischemic stroke by three times and Alzheimer's disease dementia by 2.9 times compared to less frequent consumption. The study highlights the need for more research into this area.
Research suggests that high levels of traffic-related air pollution can lead to lower levels of high-density lipoprotein (HDL) cholesterol, also known as "good" cholesterol. This can increase the risk of cardiovascular disease by reducing the number and functionality of HDL particles.
A recent study found that women with overactive bladder who received antimuscarinics were 38% more likely to develop depressive disorder within three years. The use of these drugs was associated with an increased risk of depression, highlighting the need for careful monitoring and consideration of alternative treatment options.
A recent study found that women with overactive bladder who received antimuscarinics were 38% more likely to develop depressive disorder within three years. The use of these drugs was associated with a higher risk of depression despite their ability to improve bladder symptoms by blocking muscarinic receptors.
A study found that real-world massage therapy produced clinically meaningful improvements in low back pain for primary care patients, with significant effects seen in adults from baby-boom and older generations. However, the benefits were not retained over time for obese patients, while those taking opioids showed less improvement.
Research published in Occupational & Environmental Medicine found a doubling of ALS risk among men exposed to very low frequency electromagnetic fields at work. High levels of exposure were associated with nearly twice the likelihood of developing the disease.
A recent study published in JAMA Neurology found that vitamin E and selenium supplements did not prevent dementia in asymptomatic older men. The study involved over 7,500 participants who took the supplements for an average of five years, but showed no significant reduction in dementia incidence among the groups.
A recent Henry Ford Health study suggests that age is not a factor in the success of shoulder replacement surgery. The research analyzed data from patients under 65 and those older than 75 with osteoarthritis, finding that both groups experienced significant improvement in shoulder function after surgery.
Research suggests that temporary episodes of dizziness upon standing may cause lasting damage to the brain, increasing the risk of cognitive decline and dementia. Middle-aged individuals with orthostatic hypotension were 40% more likely to develop dementia than those without it.
A recent study published in PLOS ONE found that people living with HIV in sub-Saharan Africa are at high risk of developing hypertension, which can lead to cardiovascular disease. The study suggests integrating routine hypertension screening into HIV clinics and expanding access to antihypertensive medications.
According to the study, Americans had sex about nine fewer times per year in 2010-2014 compared to 1995-1999. The decline is attributed to birth cohort, with later-born generations having sex less often than those born earlier.
A recent study published in the Journal of the American College of Cardiology suggests that increased physical activity and lower body mass index (BMI) are associated with a reduced risk of heart failure with preserved ejection fraction (HFpEF), a subtype of heart failure. The research, which pooled data from three cohort studies invol...
A new study called Latino Core aims to learn about the aging process and risk factors for Alzheimer's disease in older Latino adults. The study will enroll over 300 participants and include yearly visits, memory exams, and brain donation to understand the pathophysiology of dementia in this population.
A study of almost 700 youth handball players found that a sudden increase in training and matches can lead to shoulder injuries. The risk is highest if the player's load is increased by more than 60% compared to the previous week.
A new UBC study reveals that gamblers who feel immersed in slot machines are more likely to have gambling problems. The research suggests that designing slots with eye-catching messages and disrupting the 'slot machine zone' state can promote more responsible play.
A large study found that long-term estrogen-based hormone therapy reduced the risk of Alzheimer's disease and improved cognitive function in postmenopausal women. The protective effect may depend on starting hormone therapy at the time of menopause, when neurons are healthy.
A new Brown University study found that SNAP benefits increase a household's overall spending on food each month, with an equivalent cash benefit leading to much smaller increases in food spending. Households receiving $100 in SNAP benefits spend around $50 more on food each month.
A new analysis of eight studies reveals that elderly individuals who experience a hip fracture are at higher risk of dying in the short term after the injury. Long-term risks also exist, with fractures linked to nearly twofold increased risk of dying eight years or more after the injury.
A study published in PLOS Medicine found that lower socioeconomic position is associated with higher adult body mass index (BMI) across generations. The association increased with age and was stronger in women than men, highlighting the need for early interventions to reduce BMI inequalities.
A large study of over 9,000 men has established harmonized reference ranges for total testosterone, enabling clinicians to diagnose hypogonadism correctly. The normal range for testosterone in non-obese European and American men between 19-39 years is 264-916 ng/dL.
A new study has found that increasing intake of EPA and DHA omega-3s can help reduce the risk of coronary heart disease, particularly among populations with high triglycerides and LDL cholesterol levels. The study analyzed data from 93,000 and 732,000 subjects across 18 randomized controlled trials and 16 prospective cohort studies.