Articles tagged with Cohort Studies
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A late-breaking abstract at the European Lung Cancer Conference presented findings on osimertinib's effectiveness as first-line treatment for EGFR mutated non-small-cell lung cancer. The study showed a high overall response rate and prolonged progression-free survival, suggesting that osimertinib may alter the biology of the disease.
A new study finds that early treatment for post-traumatic stress disorder (PTSD) significantly reduces symptoms, but does not prevent long-term suffering. The research suggests that prolonged exposure and cognitive therapy can shorten the recovery time, but may not reduce PTSD prevalence.
Researchers at Rush University Medical Center are conducting a five-year randomized trial to test the MIND diet's effects on cognitive decline and Alzheimer's disease incidence. The study will enroll 600 individuals aged 65+ and evaluate the diet's impact on brain structure, cognition, and health outcomes.
A rare study of attitudes to death and dying amongst the very old reveals that this group is willing to discuss their end-of-life care, but rarely does so. The research found that most older people feel ready to die and would prefer a peaceful, pain-free passing.
A study found that the prevalence of treated diabetes increased from 5.2% to 7.7% in the US, while estimated spending for insulin per patient rose from $231 to $736 between 2002 and 2013. Insulin prices skyrocketed, with average prices increasing by 197% over the same period.
New research from South Korea suggests that higher dietary calcium intake may lower the risk of cardiovascular disease in older people, but not stroke and fracture risk. In a population with low calcium intake, higher dietary calcium was significantly associated with decreased risk of CVD.
The study suggests that PSA screening should be extended and higher biopsy thresholds used to preserve benefits while controlling harm and costs, potentially making it a more cost-effective strategy.
Researchers found that physical activity among children is lower in autumn and winter compared to spring and summer. The study highlights the need for increased active opportunities during the colder months to support children's health and development.
A study published in JAMA Surgery found that gastric bypass surgery significantly reduced mortality rates in patients aged older than 35 years. The lack of mortality benefit for younger patients was attributed to a higher number of externally caused deaths, mainly among women.
Researchers found that 56% of elective resections for uncomplicated diverticulitis occurred after fewer than 3 episodes, suggesting a need for further investigation into appropriate care guidelines. The study included 87,461 patients and analyzed inpatient, outpatient, and antibiotic claims.
Two Penn professors, Dorothy Roberts and Sarah Tishkoff, co-authored a piece in Science journal arguing that the use of genetic concepts of race is problematic and harmful. They recommend using terms like ancestry and population instead.
A new study published in PLOS Medicine found that Parkinson's patients experience a higher risk of injurious falls and hip fractures up to 30 years before diagnosis. This suggests early signs of balance issues may be an indicator of the disease.
Research published in Diabetologia reveals that each extra hour of daily sedentary time is associated with a 22% increased risk of developing type 2 diabetes. Participants with type 2 diabetes spent more time sedentary, highlighting the importance of reducing sedentary behavior in diabetes prevention.
A study found that both short and long sleep durations in pregnancy are associated with extreme gestational weight gain. Poor sleep has been linked to adverse pregnancy outcomes, and the study provides a potential mechanism for this association.
A study found that individual risk-taking propensity is subject to change throughout life, especially in domains of work and recreation. Women are less prone to take risks than men across the lifespan, while openness to experience and extraversion are associated with increased risk-taking propensity.
A recent study published in The BMJ found that increased flavonoid consumption was associated with less weight gain. The largest association was seen for anthocyanins, flavonol polymers, and flavonols, with daily intake linked to a reduction of 0.16-0.23 lbs (0.07-0.10 kg) over four-year intervals.
A recent study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that consuming soy regularly may protect women undergoing infertility treatments from poor success rates linked to bisphenol A exposure. Women who did not eat soy foods had lower embryo implantation rates and fewer live births with ...
A study suggests that changing dosing instructions from teaspoons to milliliters can significantly reduce the risk of dosage errors. The researchers found that using measuring cups with milliliter markings leads to more accurate dosages, resulting in a 50% decrease in errors.
A cohort study found a bidirectional association between intimate partner violence and depression among pregnant women and new mothers in South Africa. The study suggests that combination interventions addressing both violence and mental health may be effective in interrupting the cycle.
Researchers used high-resolution imaging to identify structural defects in bones of people with type 2 diabetes, which can weaken them and increase the risk of fractures. The study found that individuals with diabetes have greater porosity in their cortical bone component, a key factor in fracture risk.
A National Institutes of Health study found that women who eat more potatoes before pregnancy may have higher rates of gestational diabetes compared to those who consume fewer potatoes. Substituting potatoes with other vegetables, legumes or whole grains may help lower gestational diabetes risk, according to the researchers.
A study found that one in ten ICU patients develops PTSD within a year of discharge, with pre-existing conditions being strong risk factors. The study also suggests that proactively organized psychological aftercare for ICU survivors is needed to address this growing issue.
A new study found that long-term ozone exposure increases the risk of ARDS in critically ill patients, with a significant association seen among trauma patients and current smokers. The study analyzed data from 1558 patients and found that higher ozone exposure was linked to increased rates of ARDS.
Researchers found that men and women who had a spine fracture and women who had a hip fracture were more than twice as likely to experience long-term widespread pain as those who had not had a fracture. Chronic widespread pain is common and leads to substantial health-related problems and disability.
Recent studies conclude that people with epilepsy have a 27-fold greater risk of sudden death than those without the disorder. Improved cause-of-death reporting and public education could prevent thousands of deaths annually.
A study found that common CF screening tests do not adequately cover genetic variants present in non-white populations, leading to late diagnoses and poorer outcomes. The researchers recommend expanding testing to include more diverse genetic analysis methods to address this disparity.
A study of Colorado local government officials found that public opinion (95.5%) and tax revenues (50%) were significant factors in their decisions to permit recreational marijuana use. Existing medical marijuana policies also played a role in shaping these decisions.
A systematic review by University of Bristol researchers found that consuming low energy sweeteners instead of sugar leads to reduced calorie intake and body weight. The study also suggests that LES beverages may be more effective than water in reducing weight, as they do not increase appetite.
A new clinical score, L-TRiP(cast), predicts the risk of venous thromboembolism (VTE) in patients with a leg cast. The model was validated in two independent cohorts and identified high-risk patients with an accuracy of 80.8%.
A study of over 1,900 young adults found that increases in self-weighing were associated with increased weight concern, depression, decreased body satisfaction, and lower self-esteem among females. This behavior may be a predictor of eating disorders, highlighting the need for obesity prevention programs to consider its impact.
A Canadian study found that black women are at a higher risk of preterm birth than white women, with rates mirroring those in the US. The study analyzed data from the Canadian Live Birth database and found that black women had an 8.9% preterm birth rate, compared to 5.9% for white women.
Researchers analyzed CRIC data to identify risk markers for adverse cardiac events in CKD patients. The study found that women have a higher risk of peripheral artery disease (PAD) compared to men, with a 1.5 times higher incidence prior to age 70.
A recent study found that tourists use peer-to-peer accommodation services for social and financial reasons, leading to broader destination choices and longer stays. The availability of these services also increases tourism demand and revenue for destinations.
A consensus approach to assessing neuropathic pain phenotypes has been developed by an international panel of experts, aiming to improve consistency and transparency in studies. The new criteria identify possible cases of neuropathic pain, emphasizing the need for additional assessments to confirm diagnosis.
A large registry study of almost 50,000 patients in Sweden found that transfusion with stored blood does not influence patient outcomes after heart surgery. The study provides firm reassurance that current blood storage practices are safe.
A systematic review found that pear consumption is associated with improved gut health and a reduced risk of chronic diseases. The study's findings suggest that pears' high fiber content may play a key role in these benefits.
A study of over 20,000 grown-ups found no substantial effects of birth order on central personality traits, including extraversion, emotional stability, and conscientiousness. Self-reported intellect showed a small effect, with firstborns reporting better vocabulary and less difficulty understanding abstract ideas.
A research group at Tohoku University has developed a comprehensive reference panel of genetic variants from 1,070 Japanese individuals through deep whole-genome sequencing. This analysis detected signatures of purifying selection on regulatory elements and coding regions, as well as structural variants that may contribute to complex h...
Researchers found that effective HIV therapy can lower the risk of HBV infection, and vaccination against HBV protects individuals from acquiring a new HBV infection regardless of HIV status. However, vaccination rates remain low among high-risk groups.
Walter R. Frontera, MD, PhD, has received the 2015 Excellence in Rehabilitation of Aging Persons Award from the Gerontological Society of America (GSA). He is recognized for his work on skeletal muscle dysfunction and exercise to slow down and rehabilitate muscle weakness and atrophy in older adults.
A recent study has found that the human visual cortex contains neurons that selectively respond to intermediate colors, not just red, green, yellow, and blue. This discovery challenges existing color encoding models and may provide clues for designing more precise multi-primary-color displays.
The study found that teleconference settings reduced discussion times but had little impact on funding decisions. Panel discussions often resulted in poorer scores compared to initial pre-meeting scores.
A new Harvard study reveals that limiting saturated fat in the diet is still effective in reducing heart disease risk, but only when replaced with unsaturated fats or whole grains. In contrast, swapping saturated fat for refined carbohydrates has no significant impact on CHD risk.
A new study published in the American Journal of Preventive Medicine found that increased risk of mortality from long periods of sitting was only associated with very occasional fidgeters. Fidgeting, even for moderately or very active women, may offer enough of a break to counteract adverse health impacts.
A large meta-analysis of four studies involving nearly 250,000 individuals found no association between moderate coffee consumption and increased risk of atrial fibrillation. The study's results suggest that people who like coffee can safely continue to consume it in moderation without the risk of developing this condition.
Researchers at Case Western Reserve University will analyze data from over 5 million solar panels worldwide to identify factors contributing to degradation. By applying an epidemiological approach, they aim to develop more reliable designs and extend the lifespan of solar panels.
A cohort study found a modest association between SSRI use and violent crime among individuals aged 15-24, with increased risks of violent arrests and non-fatal injuries. In contrast, no significant associations were found for older adults, suggesting potential age-related differences in the link between SSRI use and violent behavior.
A systematic review and meta-analysis of 11 million patients found that diabetic women are 40% more likely to suffer acute coronary syndromes than diabetic men. The study highlights the need for comprehensive risk control and early diagnosis in female patients with diabetes.
A pooled analysis of available evidence finds that eating a lot of fish may help curb the risk of depression in Europe. The association is equally significant among men and women, with a 17% reduction in depression risk found for those eating the most fish compared to those eating the least.
A new study of over 500 Black and Latino college students confirms that financial resources are a significant obstacle to success. Students who started with high levels of financial distress were more likely to experience depressive symptoms and lower GPAs.
A recent study by the University of Warwick found a significant link between premature birth and decreased intelligence, reading, and mathematical ability in adulthood. The research also highlighted an impact on earnings into adulthood, with preterm-born individuals more likely to be manual workers or have lower family incomes.
A recent study has found that preterm birth is associated with lower academic abilities in childhood and lower educational attainment in adulthood, leading to less wealth. The research also showed that the effects of prematurity on math abilities can last into the fifth decade of life.
A research group has designed the first ever SNP array optimized for the Japanese population, covering the whole-genome region from which SNPs possessed by Japanese people can be obtained with high accuracy. The Japonica Array offers improved genotype imputation accuracy, accelerating personalized healthcare and medicine research.
A recent study published in European Heart Journal found that most patients with cardiac resynchronisation therapy (CRT) pacemaker would not benefit from the addition of a defibrillator. The CeRtiTuDe cohort study analyzed data from 1,705 consecutive patients implanted with CRT between 2008 and 2010 in France.
The VISION Study found that preoperative statin use is linked to a lower risk of cardiovascular complications and mortality after noncardiac surgery. Statins were shown to be associated with a 17% reduction in cardiac complications and a 43% reduction in mortality.
A new study suggests that women and men in the military have similar rates of developing posttraumatic stress disorder (PTSD) after combat. The study found that 6.7% of women and 6.1% of men developed PTSD, with no significant differences in severity.
Researchers at University of Michigan Health System tested strategically placed sound acoustic panels in hallways around patient rooms, reducing noise by 3-4 decibels. The study found a significant impact on patient satisfaction and hospital scores, highlighting the importance of minimizing noise levels in healthcare environments.
A new serum miRNA panel has been identified as a potential biomarker for diagnosing non-small-cell lung cancer (NSCLC) in ethnically diverse patients. The panel, consisting of five serum microRNAs, was found to have high sensitivity and specificity for detecting NSCLC in both Chinese and American cohorts.
Regular exercise in adolescence is associated with a reduced risk of cancer and all-cause mortality in women. Participation in team sports during the teen years also shows a protective effect against cancer death later in life. The study suggests that promoting exercise participation in adolescence could have important public health im...
A comprehensive study by the American Cancer Society found no association between repeated cycles of intentional weight loss and cancer incidence in men or women. The research suggests that people should be encouraged to try to lose weight despite potential regain, as it may have benefits beyond just weight management.