Articles tagged with Cohort Studies
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A systematic evidence review suggests that cognitive decline following invasive heart procedures is unlikely in older adults, with little to no difference found between treatment groups. However, individual study quality was low and more research is needed to confirm these findings.
A study published in Menopause found that postmenopausal women with comorbid depression or urinary incontinence experience greater negative impacts from vaginal symptoms, affecting daily living, emotional well-being, self-concept, and body image. Regular sexual activity may protect against these effects.
A study published in Molecular Psychiatry identified a genetic mutation linked to healthy information processing, shedding light on cognitive aging and age-related diseases. The CADM2 gene was found to be strongly associated with performance on tests of information processing speed.
The Group Health-University of Washington Adult Changes in Thought (ACT) study has been awarded nearly $13 million to continue tracking the aging process, particularly in the brain. The study aims to identify risk factors for conditions like dementia and promote healthy aging through data-driven insights.
The Lymphoma Epidemiology of Outcomes Cohort Study will enroll 12,000 NHL patients and follow them for long-term prognosis and survivorship. The grant aims to improve the length and quality of life for NHL survivors.
Researchers at UCSF found that frequent premature ventricular contractions (PVCs) are associated with heart failure incidents and increased mortality. PVCs can be prevented through medical or ablation therapy, suggesting they may be a modifiable risk factor for congestive heart failure and death.
A recent study found that approximately 1 in 6 aging individuals would be reclassified as having 'at goal' blood pressure under the new guidelines, despite frequent use of antihypertensive medications. The study suggests that less stringent blood pressure goals may increase the risk for heart attacks and strokes among older adults.
A study of children with nonsyndromic orofacial clefts and their relatives found that affected families do not have a significantly higher genetic risk for dental anomalies. Instead, the prevalence of dental anomalies is primarily due to physical consequences of the cleft and surgical interventions.
Research from the University of Copenhagen found that maintaining a good night's sleep helps maintain a healthy lifestyle. Smokers who slept normally were more likely to quit than those with disturbed sleep patterns. Improved sleep also reduced high-risk alcohol consumption and physical inactivity.
The NIH panel recommends increased research funding and education for healthcare providers to address the diagnostic challenges and limited knowledge surrounding ME/CFS. Recent insights into possible causes, such as brain changes and immune imbalance, offer hope for eventual understanding and effective treatments.
A study published in JAMA Internal Medicine estimates that cigarette smoking is responsible for nearly half of deaths from 12 smoking-related cancers among adults aged 35 and older. Lung cancer accounts for a significant proportion of these deaths, with approximately 80% of cases attributed to smoking.
A study found that physical activity declines over time in patients with chronic obstructive pulmonary disease (COPD), worsening lung function and health status. Sustained physical inactivity is associated with progression of exercise intolerance and muscle depletion.
Research found that consuming at least 10g of nuts or peanuts daily lowers mortality rates for various causes, including respiratory disease and neurodegenerative disorders. The effects are seen in both men and women, with equal reductions.
A new study found that severe restless legs syndrome (RLS) is associated with a higher risk of stroke. The research, published in SLEEP, suggests that RLS severity may be considered an early risk factor for stroke, warranting modifications in clinical management.
Researchers analyzed updated temperature data and found no decrease in warming rate between 20th and 21st centuries. The study suggests the 'hiatus' was an illusion created by earlier data biases.
A new smartphone-based system called Peek has been shown to be as accurate as traditional charts in testing visual acuity. The app, designed by the London School of Hygiene & Tropical Medicine, uses a unique piece of hardware and software to test eyesight easily and affordably in community settings.
A large European cohort study found that higher fibre intake was associated with a lower risk of type 2 diabetes. Cereal fibre had the strongest inverse association, suggesting it may help maintain a healthy weight and reduce the risk of developing diabetes.
Researchers from NYU Langone present 30 abstracts on various cancer types, including immunotherapy studies for melanoma and pediatric leukemia. Key findings highlight the potential for personalized medicine and improved outcomes in cancer patients.
Research finds that socioeconomic status and race/ethnicity are key drivers of HIV seroconversion among young men who have sex with men. Younger age at sexual debut is also associated with a greater likelihood of HIV seroconversion.
Researchers found that quitting smoking is associated with a temporary deterioration in blood glucose control, which can last up to three years. The study suggests that smokers with type 2 diabetes should expect to take extra care to keep their blood glucose levels well-controlled after quitting smoking.
A new study found that living liver donors experienced lower sexual function at evaluation phase and three months after surgery. Donor education prior to surgery may help ease concerns and improve recovery.
A new study found that patient portals exacerbate existing health disparities, with less educated and minority patients being less likely to use electronic medical records. Patients with low health literacy skills were 3.5 times more likely to be registered than those without these skills.
A new study presented at The International Liver Congress 2015 showed high rates of sustained virologic response and good tolerance when using sofosbuvir and daclatasvir-based regimens in patients with recurrent hepatitis C. These results support the use of interferon-free regimens in managing liver transplant patients infected with HCV.
A large cohort study found that long-term use of entecavir (ETV) or tenofovir (TDF) results in excellent 5-year survival for Caucasian patients with chronic hepatitis B (CHB), with a significant proportion of deaths coming from liver-unrelated causes. The development of hepatocellular carcinoma plays a major role in mortality.
A study found a strong correlation between breast arterial calcification and coronary artery calcification, suggesting that mammography could help identify women at risk of heart disease. The presence of BAC was linked to an increased CAC score, highlighting its potential as a preventive measure.
A Spanish study involving over 4,400 adults found no link between regular yogurt consumption and improved physical and mental parameters. The study suggests that more specific instruments are needed to determine potential benefits of yogurt on health.
A new study suggests global warming is not as fast as predicted, with natural variability accounting for recent temperature changes. This 'middle-of-the-road' scenario could result in 11-year hiatuses in warming, making it more plausible than the most severe IPCC projections.
A new Finnish study found that low birth weight at birth is associated with a higher risk of disability pension due to mental disorders. This can lead to an early exit from the workforce, resulting in a substantial loss to the economy.
A recent study published in the New England Journal of Medicine found that BGI's NIFTY test outperformed other noninvasive prenatal screening tests. The test correctly detected 81% of cases with nonmosaic karyotypes, while incorrectly identifying 17% of trisomy 21 and XXX/XXY abnormalities as positive.
A study found that individuals on insulin experienced significantly higher levels of inflammation compared to those living in lower traffic areas. People taking oral diabetes medications did not show the same increase in inflammation, suggesting a potential protective effect.
A new study finds that photovoltaic panels outperform green roofs and white roofs in cold Canadian climate. Green roofs are the only option to reduce both heating and cooling energy use, while photovoltaic panels demonstrate high environmental performance across all impact categories.
A new study found that night owls are more likely to develop diabetes, metabolic syndrome, and sarcopenia than early risers. Night owls tend to have poorer sleep quality and engage in unhealthy behaviors like smoking and late-night eating.
A new University of Copenhagen study found that exercise reduces premature mortality risk more than air pollution, even in polluted urban areas. The research suggests exercising in green spaces with low air pollution is still beneficial.
The presentation highlights how women are being portrayed as equals to men in superhero fiction, with characters like Juliette and Agent May exhibiting intelligence, strength, and practicality. This trend is long overdue, recognizing a loyal female comic book fan base that seeks to see women treated as heroes too.
A new risk score called Globorisk predicts 10-year heart disease and stroke risk for individuals aged 40+, using data from eight cohort studies with over 50,000 participants. The score can be updated to fit local conditions and risk factor levels in different countries.
A new study finds that recently infected individuals with HIV are not as likely to infect others as previously estimated, suggesting a potential impact on Treatment as Prevention programs. The researchers used two approaches to estimate acute phase infectivity and found estimates to be significantly lower than previous studies.
A study found that pathologists' diagnoses for breast biopsies have a high rate of disagreement, especially for cases of atypical hyperplasia and ductal carcinoma in situ. The researchers suggest that obtaining a second opinion for these cases could help reduce unnecessary treatment.
A large cohort study found no association between dietary dioxin exposure and breast cancer risk in post-menopausal women, contradicting previous studies on environmental contact with dioxins. Higher dioxin intake was linked to a decreased risk of hormone-independent breast cancer.
A Norwegian Institute of Public Health study finds that maternal levels of DDE associated with rapid infant growth, while PCB153 in milk linked to decreased growth. The study highlights the need to reduce environmental pollutants to protect children's development.
A study by AIBS found that 35% of conflicts were self-reported by review panel members, while 65% were identified by panel managers. The researchers suggest improving COI reporting and detection methods to maintain high ethical standards.
A 20-year study found that improved air quality in Southern California led to significant gains in lung function development among millennial children. Lung growth accelerated as air pollution declined, resulting in lower rates of abnormally low lung function and reduced risks of respiratory disease.
A Vanderbilt University-led study has discovered that peanut consumption is associated with reduced total mortality and cardiovascular disease mortality across all racial and ethnic groups. The study, based on three large cohort studies, found a significant link between increased peanut intake and lower mortality rates.
A large nationwide cohort study found that people with ADHD have a lower life expectancy and are more than twice as likely to die prematurely as those without the disorder. Accidents were the most common cause of death in individuals with ADHD, and women had a higher relative risk of premature death compared to men.
A new study published in Environment International found that people living near the coast in England have higher vitamin D levels than those inland. The research linked sunlight data to vitamin D levels, revealing a strong correlation between coastal living and improved vitamin D levels.
A study found that cell free DNA analysis is less effective than sequential screening for detecting all fetal chromosomal abnormalities. Sequential screening detected an 81.6% success rate and a 4.11% false positive rate, while cell free DNA detection had a lower 68% success rate at a one percent screen positive rate.
The EPIPAGE 2 study found a significant improvement in the survival of premature infants in France, with survival rates increasing by 14% for infants born between 25-29 weeks. However, results for extremely premature infants show little progress, highlighting the need for better care and monitoring.
A new study reveals that worsening health conditions can serve as a predictor to mortgage distress, increasing the risk of default and foreclosure. The study found that middle-aged adults with worsening chronic conditions face nearly twice the risk of mortgage default compared to those without worsening conditions.
Participants with asthma had a higher risk of developing obstructive sleep apnea compared to those without asthma. Asthma duration was also found to be related to the development of new OSA and habitual sleepiness.
A comprehensive analysis found that the NIH spends only 7-9% of its budget on behavioral interventions to prevent NCDs, despite 70% of US deaths being due to these diseases. Increasing funding for prevention research could save lives and reduce healthcare costs.
A large cohort study found that women experiencing moderate to severe hot flashes and night sweats have lower bone mineral density and higher rates of hip fracture. Women with these symptoms are more likely to have issues with bone health than their peers, highlighting the need for healthy lifestyle habits to prevent osteoporosis.
A study of over 80,000 women found a significant association between specific ABO blood groups and an increased risk of type 2 diabetes. Those with blood groups A, B, and AB had a higher risk compared to individuals with group O blood.
A recent study published in JNCI Journal of the National Cancer Institute found no association between migraine and breast cancer. The researchers analyzed data from 115,378 women and concluded that migraine was not associated with breast cancer risk or differences in endogenous sex hormone levels.
A study from the University of Texas at Dallas found that family-friendly policies significantly increase productivity and are related to higher labor productivity. The study also discovered a positive relationship between unionization and increased productivity and lower turnover rates.
Ramy Arnaout has been awarded a two-year grant to analyze antibody repertoires of over 1,000 Americans to clarify the link between antibodies, cardiovascular disease, and aging. The goal is to determine individual treatment needs for patients with cardiovascular disease.
A high intake of yogurt has been found to be associated with a lower risk of developing type 2 diabetes. The researchers found that high consumption of yogurt was associated with a reduced risk, while other dairy foods did not show this association.
A new study published in Brain: A Journal of Neurology found that a medium amount of physical activity can lower the risk of Parkinson's disease. Participants who spent more than six hours per week on household and commuting activities had a 43% lower risk of developing the disease.
A comprehensive analysis of sex-specific differences in end-stage kidney disease treatment found that more men than women are on hemodialysis. Women's survival after hemodialysis is virtually equal to men's survival, but they were not receiving treatment as early, leading to higher mortality rates.
A new study published in Circulation found that replacing saturated fat with polyunsaturated fat reduces the risk of coronary heart disease by 9% and death from CHD by 13%. The researchers analyzed data from 310,602 individuals and found that higher intake of linoleic acid resulted in a lower risk of CHD.
A new study found that older adults who feel comfortable with the aging process are more proactive in seeking preventive health care services. These individuals were more likely to undergo regular health screenings, such as cholesterol tests and mammograms, compared to those who were less satisfied with aging.
More frequent physical activity was associated with fewer depressive symptoms across various age groups, while less frequent activity increased symptoms. The study used data from over 11,000 participants and found a significant correlation between increased physical activity and lower levels of depression.