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Second wave of kids with MIS-C had more severe illness than first wave, according to new Children’s National Hospital study

A new prospective cohort study of 106 patients at Children’s National Hospital found that the second wave of kids with multi-system inflammatory syndrome in children (MIS-C) had more severe illness compared to the first wave. Despite this, both cohorts had similarities in cardiac outcomes and length of stay.

SourceChildren's National Hospital·JournalThe Pediatric Infectious Disease Journal·DateNov 10, 2021

Computational techniques in ICU: Neural synchrony predicts outcome after coma

Researchers used sound processing to examine neural synchrony in comatose patients. They found that higher neural synchrony was predictive of a favorable outcome, with indistinguishable levels from healthy controls. The study also revealed surprising neural complexity, with reduced complexity in survivors compared to non-survivors.

SourceInselspital, Bern University Hospital·JournalNeuroImage·TypeComputational simulation/modeling·DateNov 5, 2021

Dartmouth study reveals new insights into how the infant microbiome impacts early childhood behavior in boys and girls

A new Dartmouth-led study found a direct association between the infant microbiome and early childhood behavioral health, with sex-specific differences. The study characterized the species of microbes present in each participant's gut and their functions, establishing that microbiome changes occur before behavioral changes.

SourceThe Geisel School of Medicine at Dartmouth·JournalPediatric Research·TypeExperimental study·DateNov 4, 2021

The importance of social support during pregnancy

New research highlights the importance of social support during pregnancy, finding that women with low levels of emotional or affectionate support are at increased risk of depression and anxiety. The study suggests that screening for social support and providing community-based services may help improve health outcomes.

SourceUniversity of Technology Sydney·JournalBMC Pregnancy and Childbirth·TypeSurvey·DateNov 3, 2021

TEDDY study compares characteristics of children diagnosed with type 1 diabetes before and after age 6

The study analyzed data from 8,502 genetically high-risk children and found that half developed type 1 diabetes before age 6, while the other half developed it between ages 6 and 12. The findings suggest a different form of type 1 diabetes emerges in children as they grow older.

SourceUniversity of South Florida (USF Health)·JournalDiabetologia·TypeData/statistical analysis·DateOct 21, 2021

Children repeatedly exposed to malaria from birth are more likely to be anemic by the age of two

A Brazilian study found that children exposed to malaria from birth are more likely to develop anemia by age two. The researchers, led by Dr. Marly Augusto Cardoso, followed 1,539 children and discovered that 12.6% were anemic, with a higher prevalence in rural areas not covered by the study.

SourceFundação de Amparo à Pesquisa do Estado de São Paulo·JournalPLOS Neglected Tropical Diseases·DateOct 13, 2021

Percutaneous image-guided microwave and cryoablation for lung sarcoma

A retrospective cohort study of 27 patients with sarcoma lung metastases found high primary technical success rates for percutaneous image-guided microwave and cryoablation. The treatment modality and tumor location did not affect local progression, and smaller tumors showed lower cumulative incidence of local progression.

SourceAmerican Roentgen Ray Society·JournalAmerican Journal of Roentgenology·TypeObservational study·DateOct 7, 2021

Exposure to tobacco smoke in early life is associated with accelerated biological ageing

A new study finds that early-life exposure to tobacco smoke is associated with accelerated biological ageing in children. The analysis of over 1,000 children in six European countries revealed that maternal tobacco smoke during pregnancy and indoor exposure to black carbon are linked to an acceleration in epigenetic ageing.

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEnvironment International·DateAug 25, 2021

The effect of metabolic syndrome traits on atherosclerosis can be reduced by increasing cardiorespiratory fitness already in childhood

A new study found that increasing childhood cardiorespiratory fitness can reduce the adverse effects of metabolic syndrome traits on atherosclerosis. The researchers discovered a two-way connection between arterial health and fat mass, with healthy arteries associated with higher fat mass in children.

SourceUniversity of Eastern Finland·JournalMedicine & Science in Sports & Exercise·TypeObservational study·DateAug 24, 2021

Study links economic mobility to racial mortality gaps

A recent study by the American Cancer Society found a strong association between economic mobility and racial disparities in mortality in the US. The study suggests that structural racism has persisted with similar magnitude across generations, leading to increased death rates among Black individuals compared to their White counterparts.

SourceAmerican Cancer Society·JournalCancer Epidemiology·TypeData/statistical analysis·DateAug 4, 2021

Higher levels of omega-3 acids in the blood increases life expectancy by almost five years

A study found that higher omega-3 acid levels in the blood are associated with a significant increase in life expectancy, similar to quitting smoking. The researchers analyzed data from over 2,200 people aged 65 and found that four types of fatty acids, including omega-3, can predict mortality risk.

SourceIMIM (Hospital del Mar Medical Research Institute)·JournalAmerican Journal of Clinical Nutrition·DateJul 22, 2021

Self-collected saliva and courier service -- A feasible diagnostic strategy for COVID-19

A new saliva collection method involves self-collection by licensed dentists followed by mailing to a laboratory, demonstrating feasibility for large-scale analysis. This approach offers a cost-effective alternative for COVID-19 diagnostics, preserving saliva samples for up to 7-10 days at room temperature with stabilizers.

Beta (South Africa) variant may increase risk for COVID-19 hospitalization and death, large-scale South African study suggests

A large-scale study from South Africa found that the Beta variant increased COVID-19 hospitalization and death risks compared to previous waves. The study suggested a higher case fatality risk of 26.9% during the second wave, highlighting the need for continued vigilance.

New risk model may improve the prediction of preterm birth

A new risk prediction model may improve the prediction of impending spontaneous preterm birth, reducing unnecessary hospital admissions and treatment costs. The model combines clinical risk factors with vaginal fluid fetal fibronectin concentration analysis, showing promising performance in predicting preterm birth within seven days.

SourcePLOS·JournalPLOS Medicine·DateJul 6, 2021

Moderna and Pfizer-BioNTech vaccines prime T cells to fight SARS-CoV-2 variants

Researchers at La Jolla Institute for Immunology found that people who recovered from COVID-19 or received Moderna or Pfizer-BioNTech vaccines have cross-reactive T cells that can target several SARS-CoV-2 variants. This reactivity is key to the body's immune response, allowing it to kill infected cells and stop severe infections.

SourceLa Jolla Institute for Immunology·JournalCell Reports Medicine·DateJul 1, 2021

COVID-linked multi-system inflammatory syndrome in children diagnosed more in Black and Latino child

A new observational study found that Black and Latino children were significantly affected by COVID-linked multi-system inflammatory syndrome, with cardiac complications more common in critically ill patients. The study also identified distinct cytokine signatures and viral sequencing patterns, shedding light on the disease's demograph...

SourceChildren's National Hospital·JournalThe Journal of Pediatrics·DateJun 25, 2021

Mount Sinai study finds that rotator cuff injuries account for nearly half of shoulder injuries among collegiate baseball players, identifies other risks

A Mount Sinai study reveals rotator cuff injuries are the most common type, accounting for nearly half of all shoulder injuries. The research also identifies other risk factors, including pitching and throwing, and highlights the need for improved injury prevention strategies.

SourceThe Mount Sinai Hospital / Mount Sinai School of Medicine·JournalThe Physician and Sportsmedicine·DateJun 24, 2021

Prenatal exposure to paracetamol associated with ADHD and autism symptoms in childhood

A study of over 70,000 European children found that prenatal exposure to paracetamol was associated with a 19% increased risk of developing autism spectrum symptoms and a 21% increased risk of developing attention-deficit/hyperactivity symptoms. The researchers also found no association between postnatal paracetamol exposure and the de...

SourceBarcelona Institute for Global Health (ISGlobal)·JournalEuropean Journal of Epidemiology·DateMay 27, 2021

Planned cesarean births safe for low-risk pregnancies

New research published in the Canadian Medical Association Journal shows that planned cesarean deliveries on maternal request are safe for low-risk pregnancies. The study analyzed data from over 422,000 pregnancies and found that mothers who requested cesarean delivery were more likely to have certain characteristics. Planned cesarean ...

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateMay 3, 2021

SARS-CoV-2 transmission risk in NBA during 2020 season

Despite having clinically recovered from COVID-19, NBA players, staff, and vendors experienced persistent viral loads, indicating a high transmission risk. The study found that these individuals were more likely to transmit the virus to others, highlighting the need for continued precautions.

SourceJAMA Network·JournalJAMA Internal Medicine·DateApr 22, 2021