Articles tagged with Cohort Studies
A UT Southwestern study found that retired football players with a history of concussions and mild cognitive impairment (MCI) scored similarly to non-athletes on verbal memory and learning tests. However, they showed lower scores on naming tests, which may be related to age-related decline rather than concussion effects.
Research highlights the need for tuberculosis (TB) screening and ongoing clinical care for people on methotrexate living in areas with high TB prevalence. Methotrexate users taking corticosteroids or immunosuppressants are at increased risk of TB infection.
A recent study found that young Finnish athletes experience higher rates of menstrual dysfunction compared to non-athletes. However, athletes reported lower levels of body weight dissatisfaction. The study suggests that low energy availability may contribute to menstrual dysfunction in young athletes.
The study found associations between specific single nucleotide polymorphisms (SNPs) and clinical features of follicular lymphoma, including tumor microenvironment composition. The researchers identified key immune-related genes associated with worse survival outcomes in patients treated with rituximab-containing regimens.
A researcher created a computer model that can distinguish high academic achievers from lower ones based on their social media posts. The model achieved an accuracy of 93.7% in predicting PISA scores, indicating students' academic aptitude.
A University of Michigan study found that nearly one-third of students who reported misusing prescription opioids as high school seniors later used heroin by age 35. The research also showed a significant increase in heroin use among individuals with a history of prescription opioid misuse, contributing to the opioid epidemic.
Research shows that high-status individuals can face biases in award decisions when judged publicly, but benefits from close social ties to judges in private settings. The study emphasizes the need for accountability and transparency in decision-making processes.
A nationwide cohort study has confirmed that non-alcoholic fatty liver disease (NAFLD) is associated with increased mortality risk, even in mild stages. The study found that patients with NAFLD had a 93% increased risk of all-cause mortality, driven primarily by deaths from extra-hepatic cancer and cirrhosis.
Adults with depression who initiated newer antipsychotic medication showed a 45% increased mortality risk compared to those using a second antidepressant. The study suggests careful consideration of antipsychotic treatment for depression, as the benefits are modest and the risks substantial.
A new study by the RAND Corporation found that American adults have increased their alcohol consumption significantly during the pandemic, with women experiencing a 41% rise in heavy drinking episodes. The overall frequency of alcohol consumption also rose among all adults aged 30 and above.
A study by University of Jyväskylä found that older adults (75-80 years) have improved muscle strength, walking speed, reaction time, verbal fluency, and cognitive performance compared to the same-aged individuals in the 1990s. Increased education was a key factor behind these improvements.
A study of over 6,500 US adults found a link between COVID-19-related symptoms and preexisting conditions, job loss, and excessive media consumption. Acute stress and depression symptoms were more closely tied to personal exposure to the virus than community-level exposure.
A recent study found that being physically active can significantly reduce the risk of developing chronic kidney disease (CKD). The study, which followed over 15,000 middle-aged adults for 24 years, showed that even moderate physical activity can lower the risk of CKD by up to 11%.
A machine learning system has been developed that can predict the development of Bipolar Disorder up to 4 years before onset in young people. The system identified risk factors such as suicidal tendencies and financial problems, allowing doctors to take preventative measures.
Researchers at UC Berkeley found a correlation between poor sleep quality and increased beta-amyloid plaques in the brain, indicating an earlier onset of Alzheimer's disease. Deep non-REM slow-wave sleep has been identified as a potential target for intervention against cognitive decline.
A study from Aarhus University found that relatives with severe long-term grief reactions have more frequent GP contact and higher medication use before bereavement. This suggests that early intervention may help prevent severe grief reactions.
A cardiac biomarker was found to have stronger associations with kidney disease progression than blood pressure in both diabetic and nondiabetic individuals. Higher levels of NTproBNP, urine NGAL, and troponin T were linked to increased rates of CKD progression.
A recent study revealed that the human gut microbiome is linked to multiple diseases and traits, including chronic obstructive pulmonary disease, atopy, and BMI. The research used genetic data to estimate microbiome composition in a large cohort of unrelated individuals, finding associations between eleven bacteria and 28 health outcomes.
A new study found that members of Generation X, who came of age during the 1980s and early 1990s, have higher rates of incarceration throughout their lives. This is due to extended criminal history under a determinate sentencing regime implemented in 1994.
A group of international scientists has developed a new definition for synbiotics, outlining a mixture of live microorganisms and selectively utilized substrates that confer a health benefit on the host. The definition aims to clarify scientific ambiguity and provide a foundation for science-based claims about synbiotic health benefits.
A study of Finnish parents reveals a link between vaccine scepticism, low trust in medical doctors, and defiance. The research also found that individuals who defy rules and recommendations are more likely to use alternative medicine.
Elevated NT-proBNP levels are associated with a reduced risk of developing type 2 diabetes, especially in women. However, those who develop diabetes with elevated NT-proBNP have a higher risk of macro- and microvascular complications such as heart attack, stroke, or severe damage to eyes, kidneys, or nerves.
A new study found that vitamin D supplementation is associated with a decrease in Megamonas bacteria and C. difficile colonization in infants, suggesting potential benefits for childhood health.
A new study in the Journal of Marketing identifies cultural variable power distance belief as a determinant of consumers' price sensitivity. Consumers high in power distance belief are less price-sensitive and more likely to seize current offers, reducing their likelihood of searching for better-priced options.
Research published in the American Journal of Obstetrics and Gynecology found that women who consume alcohol during early pregnancy face a higher risk of miscarriage. The study analyzed data from over 5,500 women and found an incremental 8% increase in miscarriage risk each week of alcohol use.
A large international study identified key genetic contributors to stroke risk in individuals of African ancestry, providing insight into ethnic-specific and global risk factors. The study found that a common variation near the HNF1A gene was strongly associated with increased stroke risk.
Researchers analyzed data from the Framingham Osteoporosis Study to explain the decline in hip fracture rates in the US. Lifestyle factors such as reduced smoking and excessive alcohol consumption contributed to the decrease, highlighting the importance of public health interventions.
Researchers found no Candida auris acquisition in healthy US international travelers returning from international trips, suggesting low risk of transmission during travel. The study's results could lead to developing a detection system for high-risk populations.
A new Boston University School of Public Health and School of Medicine study finds that genetic risk factors for dementia can be lowered by improving cardiovascular health. Participants with a high genetic risk score were 2.6 times more likely to develop dementia, but those with good cardiovascular health were half as likely.
The CHASING COVID study follows a diverse cohort of thousands of adults to understand the effects of COVID-19 on mental health, employment, and economic outcomes. The study aims to inform the response to the pandemic and future pandemics with knowledge generated from its longitudinal epidemiologic design.
A new UCL-led study reveals that people in their 40s and 50s are likely to suffer more years of ill health than older generations. The study found a greater prevalence of ill health among those born later, with conditions such as diabetes and obesity affecting people earlier.
Researchers have identified a new biomarker, asymmetric dimethylarginine (ADMA), associated with cognitive decline in old age. The study found that ADMA levels were linked to decline in cognitive performance assessments after four years.
A new study found that women with higher manganese levels in early pregnancy had a lower risk of developing preeclampsia later on. The researchers analyzed data from over 1,300 women and found an association between higher manganese levels and reduced preeclampsia risk.
Researchers found that certain gut bacteria not following a day-night rhythm can serve as an indicator for potential type 2 diabetes. Mathematical models also suggest this microbial risk signature helps in diagnosing diabetes, improving diagnosis and outlook of the disease.
Researchers found that symptoms like nausea and vomiting can occur at any time of day, not just morning. A significant number of women experience these symptoms throughout the waking day.
A recent study by the University of Texas M. D. Anderson Cancer Center found that greater inactivity is independently associated with a higher risk of dying from cancer. Replacing sedentary time with physical activity, such as 30 minutes of cycling or walking, can lower this risk.
A KKH-led study evaluates a novel clinical protocol to screen and triage women with threatened miscarriages, saving pregnancies and reducing progestogen use. The protocol uses a single serum progesterone test to guide clinicians in managing patients.
Researchers discovered a link between small airways and increased COPD risk in non-smokers. People with smaller airways relative to their lungs may have lower breathing capacity, making them more susceptible to COPD.
A new study in Frontiers in Immunology found that treatment with interferon (IFN)-α2b significantly reduced the duration of detectable virus in upper respiratory tract and blood levels of inflammatory proteins IL-6 and CRP, suggesting potential for an effective antiviral intervention
A new lung cancer screening cohort study demonstrates low adverse event rates and detects 70% of diagnosed cases at early stages. Family medicine plays a critical role in expanding lung cancer screenings to underserved populations.
A new study found that middle-aged adults reported more daily stress and lower well-being in the 2010s compared to the 1990s. The researchers attribute this increase to the added responsibilities of childcare, eldercare, and work, as well as the pace of technological advances.
A study by University of Cambridge researchers found that men and women aged 40-79 who engage in moderate physical activity are 25-27% less likely to have frequent hospital admissions. This translates to a potential annual savings of £247 per person for the NHS, amounting to 7% of UK health expenditure.
A study published in The BMJ found that Mexico's sugary drinks tax led to significant reductions in soft drink consumption. After three years, the probability of non-consumers increased by 4.7 percentage points and low consumers by 8.3 percentage points.
A new study by Boston University School of Public Health found detectable levels of DDT and other banned organochlorine pesticides in the blood of over 60% of Detroit-area black women. The chemicals were linked to tobacco, alcohol, and water consumption, posing hormonal and metabolic issues.
A study published in the Journal of Clinical Sleep Medicine found that geodesic measurements from 3D photographs predicted sleep apnea with high accuracy. The algorithm's accuracy was 89%, outperforming traditional linear measurements alone, and identified key facial features such as neck width and lower jaw retrusion as indicators.
Research published in Diabetologia found that obesity increases type 2 diabetes risk by at least 6 times, even among those with low genetic risk. The study highlights the importance of weight management and healthy lifestyle in preventing type 2 diabetes across all genetic risk groups.
Researchers found that 70% of electronic consultations were appropriate and 81% associated with avoided face-to-face visits. This study suggests that e-consults can improve patient access to specialists and reduce travel costs.
Research published in Thorax journal found a heightened risk of lung cancer in people with COPD who have never smoked. The risk is comparable to that of smokers without chronic lung disease, suggesting early detection may reduce treatment complications.
A study of over 4000 people finds that emotional resilience and extroversion can reduce loneliness, while social isolation is more significant for older adults who live alone. The research highlights the importance of understanding loneliness in different generations.
Newly qualified teachers in England reported higher levels of life satisfaction and wellbeing compared to other graduates. However, they were more likely to believe that hard work in Britain is unrewarded, with only 30% agreeing that it is rewarded.
A new study found that high blood pressure in young adulthood is associated with significant declines in cognitive function and gait in midlife. The research, published in Circulation, suggests that treating high blood pressure earlier may prevent future cognitive decline and mobility issues.
A large US-based observational study found no association between moderate egg intake and increased cardiovascular disease risk. Egg consumption was not linked to higher rates of heart attacks, strokes, or coronary heart disease. However, replacing eggs with processed red meat may be associated with an increased CVD risk.
German and Canadian psychologists have developed a predictive model for relationship longevity, identifying key features that indicate a successful or unsuccessful partnership. Couples who start with similar needs and maintain individual independence tend to stay together longest, while those with differing happiness levels are more li...
Scientists at the University of Alberta found that prenatal fruit exposure enhances memory consolidation in infants, suggesting a nonpharmacological intervention to improve infant cognition. The study replicated previous findings in humans and fruit flies, offering valuable information for pregnant mothers.
A study published in JAMA found that polygenic risk scores are not a reliable predictor of coronary heart disease (CHD) in patients, contradicting long-held expectations. The researchers analyzed data from over 7,000 adults and concluded that these genetic tests provide limited information about who will develop CHD.
A UMass Amherst study found that prenatal phthalate exposure is associated with autistic traits in young boys, but adequate folic acid supplementation during early pregnancy may mitigate these effects. The study analyzed data from over 2,000 pregnant women and followed the development of their children until age 3 and 4.
A new study by researchers at the University of California San Diego confirmed an association between human milk oligosaccharides (HMOs) in breast milk and infant growth. High concentrations of certain HMOs were linked to increased height and weight, while low concentrations were associated with reduced growth.
A new study finds that young infants exposed to common household cleaning products are more likely to develop childhood wheeze and asthma by three years of age. The study, published in the Canadian Medical Association Journal, suggests that chemicals in cleaning products can damage respiratory tract cells, increasing the risk of asthma.
A study found that reducing animal product intake and following a primarily plant-based diet can decrease the risk of heart disease by minimizing the adverse effects of a gut-microbiome associated with increased risk of coronary heart disease. Higher TMAO levels were linked to a 67% higher risk of CHD.
Research shows that personal energy choices can be contagious, influenced by social norms, observation, word-of-mouth communication, and trusted community leaders. The study identifies factors that affect the impact of peer influence, including individual characteristics, relationship strength, learning processes, and behavior complexity.