Articles tagged with Cohort Studies
Comprehensive exploration of living organisms, biological systems, and life processes across all scales from molecules to ecosystems. Encompasses cutting-edge research in biology, genetics, molecular biology, ecology, biochemistry, microbiology, botany, zoology, evolutionary biology, genomics, and biotechnology. Investigates cellular mechanisms, organism development, genetic inheritance, biodiversity conservation, metabolic processes, protein synthesis, DNA sequencing, CRISPR gene editing, stem cell research, and the fundamental principles governing all forms of life on Earth.
Comprehensive medical research, clinical studies, and healthcare sciences focused on disease prevention, diagnosis, and treatment. Encompasses clinical medicine, public health, pharmacology, epidemiology, medical specialties, disease mechanisms, therapeutic interventions, healthcare innovation, precision medicine, telemedicine, medical devices, drug development, clinical trials, patient care, mental health, nutrition science, health policy, and the application of medical science to improve human health, wellbeing, and quality of life across diverse populations.
Comprehensive investigation of human society, behavior, relationships, and social structures through systematic research and analysis. Encompasses psychology, sociology, anthropology, economics, political science, linguistics, education, demography, communications, and social research methodologies. Examines human cognition, social interactions, cultural phenomena, economic systems, political institutions, language and communication, educational processes, population dynamics, and the complex social, cultural, economic, and political forces shaping human societies, communities, and civilizations throughout history and across the contemporary world.
Fundamental study of the non-living natural world, matter, energy, and physical phenomena governing the universe. Encompasses physics, chemistry, earth sciences, atmospheric sciences, oceanography, materials science, and the investigation of physical laws, chemical reactions, geological processes, climate systems, and planetary dynamics. Explores everything from subatomic particles and quantum mechanics to planetary systems and cosmic phenomena, including energy transformations, molecular interactions, elemental properties, weather patterns, tectonic activity, and the fundamental forces and principles underlying the physical nature of reality.
Practical application of scientific knowledge and engineering principles to solve real-world problems and develop innovative technologies. Encompasses all engineering disciplines, technology development, computer science, artificial intelligence, environmental sciences, agriculture, materials applications, energy systems, and industrial innovation. Bridges theoretical research with tangible solutions for infrastructure, manufacturing, computing, communications, transportation, construction, sustainable development, and emerging technologies that advance human capabilities, improve quality of life, and address societal challenges through scientific innovation and technological progress.
Study of the practice, culture, infrastructure, and social dimensions of science itself. Addresses how science is conducted, organized, communicated, and integrated into society. Encompasses research funding mechanisms, scientific publishing systems, peer review processes, academic ethics, science policy, research institutions, scientific collaboration networks, science education, career development, research programs, scientific methods, science communication, and the sociology of scientific discovery. Examines the human, institutional, and cultural aspects of scientific enterprise, knowledge production, and the translation of research into societal benefit.
Comprehensive study of the universe beyond Earth, encompassing celestial objects, cosmic phenomena, and space exploration. Includes astronomy, astrophysics, planetary science, cosmology, space physics, astrobiology, and space technology. Investigates stars, galaxies, planets, moons, asteroids, comets, black holes, nebulae, exoplanets, dark matter, dark energy, cosmic microwave background, stellar evolution, planetary formation, space weather, solar system dynamics, the search for extraterrestrial life, and humanity's efforts to explore, understand, and unlock the mysteries of the cosmos through observation, theory, and space missions.
Comprehensive examination of tools, techniques, methodologies, and approaches used across scientific disciplines to conduct research, collect data, and analyze results. Encompasses experimental procedures, analytical methods, measurement techniques, instrumentation, imaging technologies, spectroscopic methods, laboratory protocols, observational studies, statistical analysis, computational methods, data visualization, quality control, and methodological innovations. Addresses the practical techniques and theoretical frameworks enabling scientists to investigate phenomena, test hypotheses, gather evidence, ensure reproducibility, and generate reliable knowledge through systematic, rigorous investigation across all areas of scientific inquiry.
Study of abstract structures, patterns, quantities, relationships, and logical reasoning through pure and applied mathematical disciplines. Encompasses algebra, calculus, geometry, topology, number theory, analysis, discrete mathematics, mathematical logic, set theory, probability, statistics, and computational mathematics. Investigates mathematical structures, theorems, proofs, algorithms, functions, equations, and the rigorous logical frameworks underlying quantitative reasoning. Provides the foundational language and tools for all scientific fields, enabling precise description of natural phenomena, modeling of complex systems, and the development of technologies across physics, engineering, computer science, economics, and all quantitative sciences.
A multicentre prospective cohort study found that only 22% of patients' previous visit information was available when they saw another doctor. This limited exchange is crucial for continuity of patient care and may be associated with poorer outcomes.
The NIH convened a panel to weigh evidence on hepatitis B management, highlighting the need for large studies and representative prospective cohort studies. The panel recommends routine screening for newly arrived immigrants from countries with high hepatitis B prevalence.
A study found that heart attack patients treated by less experienced physicians had lower use of evidence-based drug therapies compared to those treated by more experienced cardiologists. The researchers recommend developing new methods to standardize prescribing practices, particularly for long-practicing physicians.
The UK's Economic & Social Research Council (ESRC) has launched the world's largest household longitudinal study, Understanding Society. The ambitious project will collect data from 100,000 individuals across 40,000 households to explore the long-term effects of social and economic change on the well-being of the UK population.
A study presented at the ASPS conference found that fat injections can correct implant wrinkling and improve breast shape in breast reconstruction patients. However, the use of fat injections for cosmetic purposes is still debated due to concerns about calcification, absorption rates, and procedure time.
A genetic association with SERPING1 has been found to be strongly linked to age-related macular degeneration, a leading cause of visual impairment and blindness. The study's findings have significant implications for the development of novel treatments for this devastating disease.
A study published in Sleep found that postmenopausal women slept longer than premenopausal women, with deeper sleep and increased total sleep time. However, the rate of change in sex hormones during menopause was also associated with poor subjective sleep quality.
A study found three genes associated with an increased risk of gout, enabling the development of a genetic risk score that can predict those at highest risk. This score could facilitate early and targeted treatments, improving outcomes for individuals affected by gout.
A study by University of Michigan psychologist Ethan Kross found that processing emotions from a distanced perspective can facilitate coping and reduce negative moods. By taking a step back and reviewing the situation from afar, individuals can rationalize their feelings and work through negative experiences over time.
Research found a significant disparity in health outcomes between African Nova Scotians and white Canadians, with rates of type 2 diabetes and circulatory disease being 13-43% higher. The study's authors suggest that genetic factors may play a role in these disparities.
A recent US study shows that living donor liver transplants for acute liver failure patients can have high survival rates and acceptable risks. The study found that 70% of recipients survived after transplantation, while the donors experienced similar complication rates as other LDLT recipients.
Research suggests that college freshmen can make their roommate relationships better by adopting an 'eco-system' approach, focusing on genuine caring and compassion. By doing so, they can reduce loneliness and build close relationships with their roommates.
A University of Michigan study found that over 80% of Air Force women deployed in Iraq experienced physical health problems, including fatigue, fever, and hair loss. The study suggests that deployment-related stressors may play a critical role in developing these symptoms.
Research suggests that homeownership promotes political involvement, particularly among those living in distressed areas. Homeowners in disadvantaged neighborhoods are more likely to vote than renters and those in privileged communities.
A study found that people with severe sleep apnea have a much higher mortality risk than those without, with an adjusted hazard ratio of 3.2. Regular CPAP use may protect against cardiovascular death, but the mechanisms are unclear.
The £28.5M funding will enable the co-ordination of data collection across existing birth cohort studies, allowing analysis across generations and investigating social, economic, and educational impacts on health and poverty. The new facility will expand the series by creating a new cohort to extend the study over 12 years.
A study by Columbia University's Mailman School of Public Health found that closing a coal-fired power plant in China significantly improved cognitive development and motor skills in exposed children. The research tracked two groups of children born before and after the plant's closure, revealing a direct positive impact on early child...
Researchers analyzed data from the 90+ Study, finding that 45% of women over 90 had dementia, compared to 28% of men. The study highlights concerns about healthcare resources for the growing 'oldest old' population.
A University of Michigan study finds that global happiness has risen substantially over the past 25 years, particularly in low-income countries experiencing economic growth and democratization. Economic factors have a smaller impact on happiness than previously thought, with social tolerance and freedom being key drivers.
Researchers identified CHD5 as a tumor suppressor gene associated with better outcomes in neuroblastoma patients. Intestinal proteins were found to be effective anti-tumor antigens in mice, potentially reducing autoimmune complications.
A study found that certain single nucleotide polymorphisms within the IL2RA gene region are associated with juvenile idiopathic arthritis. Three specific SNPs were investigated and one was significantly associated with UK cases of JIA, especially in female patients and those positive for antinuclear antibodies.
Studies find RA patients have a double risk of CVD events compared to the general population. The risk is comparable to that of people with type 2 diabetes. Healthcare professionals should advise patients on healthy lifestyle and early symptoms.
A study published in Cortex found that children who can read but struggle with spelling are more likely to be right-handed. This subgroup of poor spellers was also found to have better hand skills, suggesting a possible link between phonetic skills and handedness.
Critically ill patients with wide glycemic variability were more likely to die and develop nosocomial infections compared to those with low variability. The study identified age, previous diabetes history, and insulin control as predictors of high variability.
A University of Michigan researcher found that concerns about safety are the main reason fewer than 13% of US children walk or bike to school. A greener environment with wide sidewalks and trees can increase parental willingness to allow kids to walk to school.
A global study of LASIK patients found that 95.4 percent are satisfied with their new vision, with similar high satisfaction rates reported in countries outside the US. The study also identified factors associated with patient dissatisfaction, which will be presented at an upcoming ASCRS symposium.
Researchers found that daytime dozing significantly increases the risk of stroke in older adults. Moderate dozing doubled the risk, while significant dozing quadrupled it. The study suggests that sleep problems may be an important and novel stroke risk factor.
A NIH panel emphasizes the importance of removing stigma associated with fecal and urinary incontinence, recommending increased public awareness and provider education. The panel also highlights the need for research studies to fill knowledge gaps and develop effective prevention and treatment strategies.
A systematic review and meta-analysis found that active smoking is associated with a 44% increased risk of type 2 diabetes. The association was strongest for heavy smokers, suggesting that smoking may contribute to insulin resistance or inadequate compensatory insulin secretion responses.
Researchers found a significant decline in commercial cigarette purchases among adolescents, while social sources increased. This decrease was linked to reduced smoking rates, suggesting that limiting access to cigarettes may be an effective strategy for curbing youth smoking.
A study of adolescent offenders found a new upper limit for ALT that is more sensitive for diagnosing liver disease. The findings suggest targeted interventions for at-risk youths, who are high-risk for HCV infection and obesity-related liver disease.
A study found that both short and long sleep durations are associated with an elevated risk of mortality. Participants who slept five to six hours or less at baseline but reported extended sleep hours had lower mortality rates, while those sleeping seven to eight hours had higher mortality rates.
A University of Iowa study found that even when both partners are highly educated and earn a significant income, women tend to sacrifice their careers for their husbands' promotions. The research suggests that entrenched gender roles contribute to this phenomenon.
Researchers have developed a powerful tool to systematically map out pathways and subpathways contributing to inflammation. This study has led to the creation of customized panels for analyzing genetic variations in inflammation pathways for European and African descent populations.
A University of Michigan study found that conversing with others for just 10 minutes can improve memory and cognitive function. The research suggests that social interaction is an effective way to boost mental abilities, comparable to traditional mental exercises.
Researchers at Karolinska Institutet found that hysterectomy significantly increases the risk of urinary incontinence, with the highest likelihood noted within five years of the removal of the uterus. Women who had a hysterectomy before menopause or after multiple deliveries were particularly at risk.
A retrospective cohort study found that elderly patients who started dialysis between 1990 and 1999 experienced significant improvements in survival rates. Patients aged 65-74 years at the start of dialysis showed a 23% improvement in survival, while those aged 75 or more saw a 15% gain.
A study found that physicians trained to perform cataract surgery in rural China showed improved vision for over 85% of patients, with nearly 96% achieving good visual outcomes. However, only 35% of patients accepted glasses prescriptions and 48% opted for surgery on their second eye due to cost concerns.
A retrospective cohort study of 18,722 hemodialysis patients found that those living farther from their attending nephrologist had increased mortality rates from all causes and infectious causes. Proximity to a nephrologist was shown to impact clinical outcomes for these patients.
A retrospective cohort study found that international medical graduates, physicians with high practice volumes, and those who were in practice longer were more likely to prescribe antibiotics inappropriately. This inappropriate prescribing is associated with increased risk of antibiotic resistance, adverse events, and healthcare costs.
Women are less likely to receive implantable cardioverter-defibrillators (ICDs) for the primary and secondary prevention of sudden cardiac death compared to men. According to a study published in JAMA, men are about 2-3 times more likely than women to receive ICDs within a year of entering the study.
A comprehensive review of over 500 studies on aspartame found no evidence of cancer, neurological damage, or other adverse effects. The study suggests that aspartame is safe at current levels of consumption and may even aid in weight control and sugar-free diets.
A new University of Michigan study shows the wealth gap is increasing steadily, with the top 2% of families seeing a nearly doubling of their net worth, while the poorest quarter of families lose ground. The poorest ten percent of families even have negative net worth.
A series of surveys shows a decline in support for religious government and an increase in support for secular political rule. Iraqis exhibit a strong sense of national identity, prioritizing being 'Iraqis' over other affiliations.
A new study links birth weight with adult health and socioeconomic success, finding that low birth weight increases the risk of poor health, lower earnings, and reduced educational attainment. The study analyzed over 35 years of data on more than 12,000 individuals from the Panel Study of Income Dynamics.
Researchers found that consuming high amounts of vitamin B6, B12, and folate from food reduced the risk of pancreatic cancer by 59%, 73%, and 81% respectively. In contrast, multivitamin use was associated with a higher risk of developing the disease.
The APS 19th Annual Convention examines how scientific investigations can lead to stigmatization of certain populations. Panelists discuss historical examples of 'stigma from science' in studies of gender, sexual orientation, ethnicity, and culture.
Researchers developed a new technique to acquire soft-tissue cross-sectional images using a flat panel C-arm fluoroscopic unit. This allows for efficient patient visits and additional clinical information that directly affects interventional therapy in 80% of cases.
A recent study published in BMC Public Health reveals a disturbingly high prevalence of self-reported drinking and driving among Spanish doctors and nurses. These health professionals are found to be more likely to engage in drink driving, with men being twice as likely to drive while intoxicated compared to women.
A retrospective analysis found patients taking risedronate (Actonel) had a lower incidence of hip fractures compared to those taking alendronate. The REAL study used a health service utilization database and provided valuable insights into the clinical effectiveness of these osteoporosis treatments.
Biosite has identified a combination of three biomarkers that performed better in assessing risk of sepsis progression. The sepsis biomarker panel may aid in the rapid assessment of patients presenting to the emergency department with signs and symptoms of sepsis.
A new study reviews recent research suggesting that adaptation to changing life circumstances is not as universal as previously thought. The study found that people adapt quickly to marriage, but take longer to recover from divorce or unemployment. Additionally, individual differences play a significant role in adapting to life events.
A large retrospective cohort study found that moderate to high levels of regular physical activity slow lung function decline among smokers and reduce the risk of developing chronic obstructive pulmonary disease (COPD). Regular exercise suppresses inflammatory markers in the lungs caused by smoking, reducing COPD pathogenesis.
A new study found that a natural family planning method called symptothermal method (STM) is as effective as the contraceptive pill in preventing unplanned pregnancies when used correctly. The STM method uses two indicators to identify the fertile phase in a woman's menstrual cycle and has an unintended pregnancy rate of 0.4% per year.
Recent studies suggest that flavanol-rich cocoa can enhance brain blood flow, potentially improving cognitive function and learning. Researchers found significant correlations between flavanol consumption and reduced rates of heart disease and cancer among the Kuna Indians in Panama.
A new study conducted by the University of Texas at Austin found that children's age and family dynamics play a significant role in shaping weekend leisure activity choices. The study reveals that children whose fathers have a higher education level are more likely to engage in active recreation, while those from single-parent househol...
A recent study published in PLOS ONE found that antiretroviral resistance testing significantly improves life expectancy and quality of life for HIV patients. The study also revealed cost savings for society, including reduced healthcare costs and increased productivity.
A study published in the American Journal of Respiratory and Critical Care Medicine found that young adults with chronic cough and phlegm are at a fourfold increased risk of developing COPD. The presence of these symptoms is an early marker of airflow obstruction.
A new study published in Annals of Internal Medicine found that moderate alcohol consumption can reduce the risk of heart attacks among men with hypertension. The study analyzed data from nearly 12,000 men and showed that drinking one or two drinks per day does not increase the risk of heart attack or stroke.
A retrospective study of 33,000 women with osteoporosis found that Actonel significantly reduced the risk of hip fractures compared to alendronate. The results showed a 46% lower incidence of hip fractures at six months and a 43% reduction at 12 months.