News on open-access publishing and its reach. Covers journal launches, open-access agreements, and research made freely available.
The human brain operates in a self-organized critical state, characterized by optimal memory and information-processing capacity. Researchers used brain imaging techniques to measure synchronization between brain regions, finding dynamic changes consistent with critical dynamics.
Scientists successfully produced biologically-active interleukin-10 in genetically modified tobacco plants, offering a potential new treatment for autoimmune diseases. The transgenic plants can produce the active cytokine at high levels without lengthy extraction and purification processes.
Research using EEG shows that guitarists' brains become more synchronized when playing together, with the frontal and central regions showing strong synchronization patterns. This finding has implications for how our brains interact during coordinated actions, such as music performance.
A study found that iron homeostasis is disrupted in prion disease-affected brains, leading to a vicious cycle of increased iron uptake. The misfolded protein PrP-scrapie causes this imbalance by altering cellular iron metabolism, paving the way for novel therapeutic strategies.
Research found that facemasks can prevent adverse cardiovascular effects caused by diesel exhaust, reducing arterial stiffness and associated risks. Wearing a facemask during exercise in smoggy cities may lead to reduced blood pressure and improved heart rate control.
Researchers found five single nucleotide polymorphisms (SNPs) in ADAM33 that were more frequent in COPD patients than non-COPD smokers. These polymorphisms, particularly S1, are associated with lung abnormalities and progressive decline in lung function characteristic of COPD.
A Brazilian study found that current guidelines for sexually transmitted infections are woefully inadequate, with only 32% of infected women correctly identified using the World Health Organization's risk assessment score. The researchers recommend rapid and less costly diagnostic tests to control the spread of STIs in adolescents.
Researchers have discovered a cryptic species of kissing bugs that co-exist with known carrier species of the Chagas disease-causing parasite, despite being genetically distinct. The study's findings suggest that understanding what keeps these species separated is crucial to developing effective control measures.
Incipient sex chromosomes have been found in New Zealand's eponymous export, the kiwifruit. The genetic linkage map of the kiwifruit reveals that a subtelomeric region bears hallmarks of an early sex-determining locus.
A Swedish study published in BMC Public Health found that teenagers are more positive towards their parents' attempts to discourage them from smoking. The most effective actions parents can take include dissuading their children from smoking and not allowing them to smoke at home.
A study by Jean-Marc Lassance and Christer Löfstedt found that female moths can distinguish between males of different ancestries and reproductive fitness based on their pheromone composition. This ability allows females to select mates that are more likely to produce offspring with the same genetic makeup, driving species formation.
Researchers have identified two causes of critical illness hypeglycemia in children: peripheral insulin resistance and primary beta-cell dysfunction. The study found that those with respiratory failure only had CIH caused by elevated insulin resistance, while those with both respiratory and cardiovascular failure had CIH caused by prim...
A study of 1060 vets in north Germany found that psychosocial stress increased with working hours, leading to demoralization and substance abuse. The research suggests a complex relationship between stress, tobacco consumption, problem drinking, and drug use.
A recent study found that post-partum haemorrhage is a significant threat to new mothers in high-income countries, resulting in severe outcomes including infertility and death. The authors recommend increased access to active management of the third stage of labour to reduce PPH rates.
Researchers used genetic markers to study coral groupings and found that skeletal shape is not a reliable way to differentiate species. This discovery highlights the need for accurate understanding of coral biodiversity to conserve coral reefs.
A new website allows scientists to collaborate on bacterial strain identification through multilocus sequence analysis. The database grows in size and utility as taxonomists add their isolates, enabling electronic taxonomy.
Researchers found that monkeys devised a near-optimal strategy by balancing sensory information and prior expectations regarding rewards. The monkeys' harvesting efficiency fell within 1-2% of the theoretical maximum, revealing impressive decision-making ability.
A multi-centre study found that osteoblast cell injections accelerated fracture healing, with increased bone growth and no significant patient complications. The treatment is considered a safe and effective alternative to traditional methods, allowing for faster recovery without surgery.
A new article suggests that gorilla lice evolved to infest pubic hair around 3.3 million years ago, possibly due to human-gorilla contact. This divergence occurred despite humans and gorillas diverging from a common ancestor at least 7 million years ago.
Researchers identified eighteen new genetic changes in rats from four continents that enable resistance to warfarin. VKORC1 gene mutations may cause heritable resistance by preventing coumarin derivatives from interfering with the reductase enzyme activity.
A systematic review of over 13,000 participants found that exposure to alcohol adverts and product placements increases drinking behavior in young people. The study suggests that counter-advertising and social marketing techniques may be effective prevention options for limiting alcohol problems in young people.
Researchers found that every second of compression pause reduces the likelihood of successful return of spontaneous circulation (ROSC) by 1%. Effective CPR requires minimal interruptions, with powerful chest compressions being crucial.
A recent study found that playing games against a virtual opponent activates different brain areas than those activated when playing against a human opponent. The medial prefrontal cortex and other regions associated with 'Theory of Mind' were more active in male players believing they were competing with another human.
Research reveals that tobacco companies in South Korea have been deliberately targeting girls and young women with marketing campaigns, using tactics such as associating smoking with body image and female emancipation. The study calls for stricter regulations and public education to combat the rise in female smoking rates.
Research followed over 2000 high- and middle-school children, finding that TV viewing times predict a poor diet in the future. Young adults who watched more than five hours of TV per day had lower intakes of fruits, vegetables, and whole grains, but higher intakes of fast food and unhealthy snacks.
Research published in BMC Endocrine Disorders shows that regular high-intensity interval training can significantly improve insulin action and glucose clearance. A three-minute sprint workout every couple of days may be the best way to cut the risk of diabetes, with substantial improvements in metabolic prowess seen within two weeks.
Expert authors advocate for a US foreign policy agenda focused on eliminating neglected tropical diseases, citing connections between NTDs and conflict. The control of these devastating diseases could be achieved at a fraction of the cost of other medical interventions.
The new journal Genomic Medicine bridges the gap between research and clinical practice, providing open access to high-quality research articles. The journal features columns by leading experts on genomic medicine and its applications.
A new editorial emphasizes the need to address the devastating impact of rape as a weapon of war, citing conflicts in the DRC, Burma, Sudan, and former Yugoslavia. The PLoS Medicine editors argue that medical journalists and editors can draw attention to this issue, influencing support for humanitarian organizations and advocacy groups.
Researchers have created gene-engineered male flies that die as embryos, outcompeting wild pests and reducing crop damage. This new method of pest control eliminates the need for radiation, increasing safety and effectiveness.
A recent study found that fainting was the most common in-flight medical emergency, accounting for 53.5% of cases. The researchers also highlighted the need for standardization in reporting in-flight emergencies, citing poor data quality as a major issue.
Researchers found that prior STD infections can lead to a genetic bottleneck in HIV transmission, allowing multiple viral variants to spread. The study suggests that the genital mucosa provides a natural barrier against infection, which can be compromised by inflammatory genital infections.
A Canadian/U.S. research team has reported a therapeutic model exploiting the natural dynamics of the 'fight or flight' system to stimulate recovery from chronic stress disorders. The HPA axis dysfunction may become chronic if driven far from its natural homeostatic rest point, leading to disorders like CFS, depression, and PTSD.
A recent study published in BMC Medicine found that individuals with high trust in mass media tend to be healthier. Young, married, and highly-educated women reported the highest levels of health, while those in Turkmenistan had the lowest opinion of their own wellbeing.
A Canadian study found that psychological concerns, such as self-efficacy and motivation/intention, are the most important barriers to an active lifestyle. The study's findings highlight the need for health promotion programs to enhance people's confidence and motivation.
Research published in International Journal of Health Geographics links outbreaks of nephropathia epidemica, a rodent-borne disease, to global warming. Warmer weather and increased food sources for voles lead to population growth and disease transmission.
A study of ancient DNA from 68 skeletal remains reveals a rapid evolution in the Icelandic mtDNA pool over the past thousand years. The original female settlers appear to be genetically less closely related to present-day Icelanders than previously thought.
Researchers found that free-range chickens are more susceptible to disease, particularly bacterial and parasitic infections. The study, published in Acta Veterinaria Scandinavica, suggests that this is due to the challenges of managing these systems, leading to higher mortality rates.
Research published in BioMed Central's Arthritis Research and Therapy found that women experience more severe symptoms, greater disability, and poorer treatment outcomes compared to men. The study of over 6,000 patients revealed a significant gender gap in disease activity measures, treatments, and clinical characteristics.
A study published in BMC Evolutionary Biology found that animal species sleeping for longer periods have reduced parasite infestation and increased immune cells. This suggests that sleep plays an important role in protecting animals from parasitic infections.
Research published in BMC Medicine found a significant association between metabolic syndrome and PTSD after controlling for other factors. Veterans with higher severity of PTSD were more likely to meet the diagnostic criteria for metabolic syndrome.
Aphids leave behind their old exoskeletons, called exuviae, to act as decoys for parasitoid wasps. This behavior helps aphids escape from parasitic attacks by giving other aphids time to flee while the wasps investigate the empty shells.
A new paper in Optics Express envisions a future with widespread use of LED lights, offering significant energy savings and environmental benefits. LEDs are predicted to save more than $1 trillion in energy costs over 10 years and lead to substantial reductions in carbon dioxide emissions.
A recent survey of doctors has found that most feel only confident in performing five out of seventeen procedures required by the NHS. The study suggests that guidance on acceptable standards is limited, and some procedures may be unachievable for all trainees.
A US death map shows that heat/drought and severe summer weather are leading causes of death, with the South and mountain west particularly vulnerable. The study highlights the importance of emergency management in reducing loss of life from natural hazards.
A supplement published in Malaria Journal reviews aspects of research agenda for global malaria elimination. Despite hurdles, progress has been made in developing malaria vaccines intended to kill all parasites in the community, reducing transmission.
Dr Ben Berkhout's multi-disciplinary approach to RNA research has provided key insights into HIV-1 replication mechanisms. He was awarded the 2008 M Jeang Retrovirology Prize for his outstanding mid-career contribution to HIV research.
A study of over 1,000 female sex workers in Cambodia found that new entrants were twice as likely to have gonorrhoea or chlamydia. The high risk is attributed to limited access to STI services and prevention information. The study highlights the need for improved health education and training programs for sex workers.
Researchers have identified MEDNIK syndrome as a debilitating genetic disorder characterized by mental retardation, enteropathy, deafness, and other symptoms. The AP1S1 gene mutation is found to cause impairment of neural networks, including the spinal cord, inner ear, and brain.
Research published in BMC Medical Education reveals a high prevalence of depression among medical students, particularly females, with symptoms including somatic and affective clusters. The study suggests that this period is crucial for professors and educators to monitor suicidal thoughts and risk in their students.
Cognitive neuroscientists successfully created an illusion of body-swapping by manipulating sensory impressions, allowing subjects to perceive a mannequin's body as their own. This discovery sheds light on how the brain constructs an internal image of the body and has potential practical uses in VR applications.
A genome-wide association study reveals genetic variants influencing metabolic capacity, affecting disease susceptibility. The study identifies four SNPs associated with variations in polyunsaturated fatty acid synthesis and breakdown of triglycerides.
Research challenges the idea that longer sperm are faster due to drag from their heads. Streamlining and tail shape may be more important factors in determining sperm performance.
A recent study published in Reproductive Health found that pregnant women who attended water aerobics classes had shorter labor durations and lower rates of analgesia requests compared to those who did not participate. The research suggests that moderate water aerobics during pregnancy may improve maternal and fetal health outcomes.
The discovery of Bundibugyo ebolavirus represents a significant addition to the puzzle of the Ebola virus genus. The new virus is genetically distinct from all other known Ebola virus species, differing by more than 30% at the genetic level. This finding has implications for the development of diagnostics, antivirals, and vaccines.
A UK study reveals that most children are meeting physical activity guidelines, but failing to eat five pieces of fruit and vegetables a day. The study found that socioeconomic background plays a significant role in dietary habits, with children from lower-income backgrounds more likely to consume healthy foods.
A new technique allows for a quantitative and precise determination of plant viability during drought stress using chlorophyll fluorescence. This method is non-invasive, easy to measure, and minimizes technical expertise, making it a valuable complement to existing methods.
Research on small skink lizards reveals extensive body shape changes over brief geological periods, with species evolving an elongate, limbless body form. The study found rapid evolution of this snake-like body form, without reversals, and estimated the loss of limbs to have occurred within 3.6 million years.
A comprehensive study of lion populations in Africa and Asia found evidence of genetic diversity, even in well-studied ecosystems. The research highlights the need to prioritize conservation efforts for declining populations over larger-scale initiatives.
Researchers developed an AI coaching system called COACH to assist older adults with moderate dementia in performing daily activities. The system uses computer vision and artificial intelligence techniques to deliver personalized reminders, resulting in increased independence for participants.