News on measuring and increasing the impact of research. Covers research-impact data, AI publishing workflows, open-access programs, and scholarly metrics.
Researchers developed a tool to identify high-risk children and adolescents with pediatric postacute sequelae of SARS-CoV-2 infection (PASC), also known as long COVID. The study found that symptoms differed by age group, with some similarities but distinct patterns across childhood ages.
Researchers developed a treatment approach using lipid nanoparticles to deliver mRNA therapy for MSUD, extending survival and reducing serum leucine levels. The study also identified a novel AAV variant with desirable biodistribution properties for targeting peripheral organs.
A University of Central Florida researcher has developed a nature-inspired filtration and conversion system that extracts carbon dioxide gas from the atmosphere to create fuels and chemicals. The device mimics the lotus surface, capturing carbon dioxide with a microsurface comprised of a tin oxide film and fluorine layer.
A self-guided CBT app, Maya, significantly reduced anxiety in young adults, with improvement levels similar to anxiety medication studies. The study found that the app's interactive platform and real-time feedback helped users learn new skills and coping mechanisms.
The University of Texas at San Antonio is partnering with Texas A&M University to co-lead SECURE Southwest, a regional center launched to enhance U.S. research security. The center aims to educate the research community about security issues and engage them in collaborative problem-solving.
Researchers explore the effect of exercise on age-related biomarkers in human skeletal muscle, revealing its potential to foster healthier aging. The study represents the first quantitative and qualitative analysis of this impact, highlighting the benefits of exercise for age-related diseases.
Researchers have developed a new method to predict protein movements by teaching AI about energetic frustration. This improves the accuracy of tools like AlphaFold2 in predicting alternative structures and functional movements. The study has significant implications for drug design, enzyme engineering, and disease mechanisms.
Researchers at the University of Cincinnati are developing a new technology using magnetic nanoparticles to deliver medications directly to the inner ear, where hearing loss occurs. The goal is to create an effective and minimally invasive treatment option for various types of hearing loss.
Researchers at UCSF have developed intelligent brain pacemakers that use AI to monitor and adjust brain activity in real-time, providing personalized treatment for Parkinson's patients. The approach, called adaptive deep brain stimulation, has shown promise in reducing symptoms such as movement problems and insomnia.
The study demonstrates how agrivoltaics systems can minimize the impact of dynamic shadows on corn yield, allowing for efficient energy production. Researchers developed a model to calculate light intensity and tracked the sun throughout the day, resulting in an 8% loss compared to traditional farming methods.
Scientists have expanded understanding of how electrons move through conductive fluids in batteries, revealing that controlling chemistry and microstructure is crucial. The research team created a universal roadmap for processing energy storage devices during manufacturing, enabling the design of better materials.
New research reveals a dangerous combination of warming waters and nutrient overload is degrading freshwater ecosystem functioning. This simplification leads to shorter food chains and vulnerable top predators, emphasizing the urgent global need to reduce pollution levels.
A new screening tool, DuMAND Checklist, has shown promise for assessing neurobehavioral difficulties in children with Duchenne muscular dystrophy and improving quality of life. The checklist covers a range of issues including behavior, psychiatric disorders, and cognitive deficits.
A new study found that job strain and effort-reward imbalance at work increase the risk of developing atrial fibrillation, an abnormal heart rhythm. The research suggests that recognizing and addressing psychosocial stressors at work can foster healthy environments.
A roundtable discussion explores the integration of positive psychology and autism, highlighting its potential to amplify strengths and improve interpersonal dynamics. The study suggests that appreciating character strengths can have a significant impact on daily life.
A study by Children's Hospital of Philadelphia researchers found discrepancies between crash reports and hospital data, suggesting incomplete or inaccurate pictures of child passenger safety. The findings emphasize the importance of enhancing injury data quality to assess transportation safety strategies.
A recent study by Harvard University researchers compares the effectiveness of one-photon (1P) versus two-photon (2P) voltage imaging in neural circuits. The study found that 2P excitation requires approximately 10,000 times more illumination power per cell compared to 1P excitation, posing significant challenges for 2P voltage imaging.
A Chinese Medical Journal study developed an AI-based system to automate embryo selection and eliminate subjectivity in IVF. The system improved human embryo assessment and selection, achieving higher accuracy in embryo aneuploidy screening than experienced embryologists.
A new study shows that empowering women through energy care work can transform community-led renewable energy programmes, promoting gender equality. The research highlights the importance of valuing multiple voices and incorporating diverse practices of care into energy transition policies.
A research project, ACCELERATE, aims to significantly reduce operational qualification time and cost in additive manufacturing by improving validation through detailed tasks and documentation. The project will tackle various aspects of AM operations, including facility controls, operator training, software configuration, and process mo...
A recent study by Binghamton University Political Science Professor Jeffrey L. Yates found that U.S. presidential elections significantly impact local prosecutor races. The researchers analyzed data from the nation's top 200 districts and discovered that incumbent prosecutors with the same party affiliation as a successful president ha...
Guan's lab will apply accumulated experience and methods to study SLC6A14, a sodium-coupled epithelial amino acid co-transporter involved in cancer and several chronic diseases. CryoEM will be used to determine the structure of SLC6A14, providing insight into its substrate specificity and inhibitory mechanisms.
Researchers discuss diverse BRAF alterations found in human cancers and strategies to inhibit them. Class I BRAF inhibitors represent a landmark achievement in precision oncology, with FDA-approved dabrafenib/trametinib for metastatic BRAF p.V600E-mutant solid tumors.
A new study led by UMass Amherst and Tufts Medical Center will provide HIV prevention, diagnosis, and treatment for people with opioid use disorders who are incarcerated. The study aims to increase the number of incarcerated individuals tested and treated, addressing a critical gap in healthcare access.
Researchers unveil retrotransposon-derived DNA zip codes that enable myeloma cell internalization, shedding light on cancer evolution and treatment response. The findings highlight the potential of zip-code technology in improving patient outcomes and advancing human health.
A WVU team investigates how different management practices affect Appalachian forest life and carbon sequestration capabilities. Preliminary data reveals changes in species distribution and ecosystem resilience to climate change.
A University of Oklahoma researcher is investigating how prenatal inflammation increases the risk of neurodevelopmental disorders like ADHD and autism. She hopes to find a way to promote fetal resilience to inflammation using antioxidants like PQQ.
A new deep learning-based inverse design method allows for the optimization of complex acoustic metamaterials, reducing noise pollution while maintaining ventilation. The approach enables ultra-broadband sound attenuation across various peak frequencies.
High nighttime temperatures accelerate leaf senescence, disrupt cellular membranes, and increase respiration rates in plants. Understanding the key metabolic pathways and molecular mechanisms involved is crucial for developing genetic modifications, breeding strategies, and management practices to enhance plant resilience.
Researchers identified a potential antigen for TCR recognition in melanoma, suggesting that RNLS protein could be recognized by T cells leading to local immune responses against the cancer. The study found that chemical complementarity between melanoma-resident TCR CDR3s and renalase-1 protein correlates with increased melanoma survival.
A new study by top researchers reveals one in five children with an older sibling diagnosed with autism spectrum disorder (ASD) are likely to be diagnosed with the disorder as well. The rate of autism recurrence is seven times higher in families with an autistic child compared to the general population.
Researchers discuss how PROM2 is a predictive biomarker of distant metastases and shorter survival among patients with stage III melanomas. They also demonstrate that runaway metastasis is closely linked to PROM2 overexpression, through increased epithelial-to-mesenchymal transition marker expression and ferroptosis resistance.
Fatigue affects up to 90% of individuals with MS, significantly impacting their daily lives. The study proposes that disruptions in the cortico-striato-thalamo-cortical loop contribute to central fatigue.
A new study by the University of Vienna found that visiting an art exhibition can reduce xenophobia and increase acceptance of immigration. Participants reported increased social awareness and empathy, which lasted for up to a week after their visit.
Researchers at the University of Houston have developed two nasal sprays, NanoSTING and NanoSTING-SN, to prevent respiratory virus transmission. NanoSTING is an immune activator that can protect against multiple viruses, while NanoSTING-SN is a pan-coronavirus vaccine that can prevent transmission to unvaccinated individuals.
A new study found that meeting partners online is positively linked to relationship success among those who have social media presence on their relationships. However, the link was absent among individuals without this social media presence, particularly in marital relationships.
A panel of experts has reached consensus on fasting terminology to enhance communication and cross-referencing in the field. The defined terms include 'fasting,' 'modified fasting,' and 'religious fasting,' among others, aiming to steer people away from unverified diets that can lead to unhealthy behaviors.
Dr. Wen Li's research aims to discover whether quantum tunneling is instantaneous and develop new detector technologies for fast electron processes. This project has the potential to impact various fields, including medicine, business, and biology.
Liheng Cai, a UVA engineering professor, has received a $1.9 million NIH grant to create advanced biomaterials that can be used to repair living tissues and build organ structures. His lab aims to develop polymers that mimic human biology and integrate healthy cells into the human body.
Researchers developed a lipid nanoparticle formulated miR-193a-3p mimic that enhances T cell mediated immune responses and induces immunogenic cell death in tumors. This study demonstrates the potential of this therapy to prolong animal survival and reduce metastasis, offering new hope for cancer treatment.
Researchers from the University of Sheffield have developed a new form of immunotherapy using nanoparticles that delays the onset of resistance to hormone therapy in prostate cancer. This innovative approach stimulates immune cells called T cells to attack cancer cells, marking a significant breakthrough in treating prostate cancer.
A research team has identified novel biomarkers in cervical mucus samples that show high diagnostic power for detecting cervical cancer. The findings suggest that analyzing local expression levels may offer a superior diagnostic strategy, potentially reducing the need for invasive procedures.
A mathematical model developed by Chris Zobel and colleagues optimizes resource allocation in urban infrastructure while considering social vulnerabilities and projected sea level rise impacts. The approach prioritizes investments that enhance resilience and mitigate socio-economic disparities, enabling informed decision-making that ba...
A new study reveals that Maasai women are gaining access to household decisions through livelihood diversification, education, and secure land tenure. This research contributes to the United Nation's Sustainable Development Goal of Gender Equality, highlighting the value of empowering decision-making for women in pastoralist communities.
A study on horse miscarriages revealed that 42% of cases were due to triploidy, a condition characterized by an extra set of chromosomes. This finding provides insight into the frequency of chromosome errors during early human pregnancy, which has been difficult to determine.
A UVA research team introduces a game-changing additive to 3D-printed concrete, enhancing its printability and mechanical properties. The study demonstrates the potential for more resilient and eco-friendly construction practices using cellulose nanofibrils.
A new study found that subclinical hypothyroidism diagnosed before 21 weeks of pregnancy is associated with higher rates of overt hypothyroidism or thyroid replacement therapy within 5 years after delivery. Women with high TSH values and elevated TPO antibodies were at increased risk.
A lack of adaptive equipment and trained staff in commercial gyms creates significant barriers to exercise for people with disabilities. The study highlights the need for more accessible options and awareness programs to encourage continued physical activity among this population.
Researchers discovered ultrastructural abnormalities in obese patients with heart failure with preserved ejection fraction (HFpEF), which may be related to the impact of obesity on muscle structure. The study suggests that reducing obesity and using certain medications could help improve HFpEF outcomes.
A new study published by US Forest Service researchers explores the impact of leaf-eating insects on forest ecosystems worldwide. The findings suggest that warmer climates affect plant-herbivore interactions, leading to changes in carbon and nutrient cycling in broadleaved forests globally.
Researchers developed a method to produce cobalt nanoparticles with controlled crystal phase, leading to higher selectivity and efficiency in hydrogenation reactions. The study showcases the potential of abundant cobalt as an alternative to noble metal catalysts.
Research from Florida Atlantic University reveals that training closer to failure can boost muscle growth, while having no clear impact on strength gains. The study analyzed data from 55 studies and suggests that individuals who aim to build muscle should work within a desired range of 0-5 reps short of failure.
A recent study explores the Clean Air Act and its impact on downwind states, highlighting challenges in regulating interstate air pollution. Downwind states face lengthy response times, infrequent petition acceptance, and burdens of proof in court, making it difficult to effectively address unequal pollution effects.
A new AI algorithm assesses immune cells in early-stage bowel cancer tumours to predict recurrence risk. The CD3 Score test has been shown to reliably identify high-risk cancers that are more likely to recur within five years of surgery, enabling clinicians to make informed decisions about chemotherapy treatment.
Researchers at Argonne National Laboratory have made significant strides in understanding the mesoscale properties of a ferroelectric material under an electric field. The breakthrough holds potential for advances in computer memory, lasers, and sensors.
A 15-year study found that apple breeding programs prioritize inner cortex firmness, leading to enhanced storability. The selected cultivars exhibited superior firmness retention, especially those influenced by 'Cripps Pink' and 'Honeycrisp'.
This study demonstrates that genomewide prediction effectively targets russet formation in apples, a complex quantitative trait controlled by many small-effect QTLs. Moderate predictive abilities were observed across various models, with the inclusion of previously detected QTLs as fixed effects not significantly enhancing predictions.
Research from the University of Illinois highlights the potential of organic nanozymes for broader applications beyond traditional uses of inorganic nanozymes. The development of sustainable, environmentally friendly materials offers a promising solution for various industries.
A study by the University of Essex found that oil and gas extraction can cause a nearly 30% decline in species richness near platforms, with pollutants like hydrocarbons up to 10,613% higher within 500m. This has a direct impact on marine invertebrates and food webs.
A recent study found that mental health disparities in Los Angeles County worsened during the COVID-19 pandemic, particularly among non-white residents. The risk of depression grew more common in areas hit hardest by deaths from COVID-19, with stark divisions observed between white and non-white communities.