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Science News for January 29, 2001


Gene study to unlock causes of stroke

Researchers will examine genetic factors that might predispose people to ischaemic stroke, using a novel molecular strategy and data from 500 patients. The study aims to identify genes involved in stroke and develop new treatments, which could increase protection against subsequent strokes.

Novel route to lupus-like disease in mice

Researchers at Howard Hughes Medical Institute have identified a link between faulty glycan construction and the onset of autoimmune diseases like lupus. Knocking out a gene involved in modifying sugar molecules on cell surfaces led to mice developing lupus-like abnormalities, including inflamed kidneys and autoreactive antibodies.

SourceHoward Hughes Medical Institute·JournalProceedings of the National Academy of Sciences·DateJan 29, 2001