Researchers found AAV DNA in 38% of men with abnormal semen analysis, but only 4.6% of those with normal semen. Further studies are needed to assess the link between AAV and infertility.
SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·DateOct 25, 2001
Scientists have identified a protein segment responsible for fibrous tissue growth leading to liver cirrhosis. They've developed a mutated version of the protein that blocks this process in mice, offering potential new hope for treating liver diseases.
SourceUniversity of California - San Diego·JournalMolecular Cell·DateOct 25, 2001
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Researchers found that exposure to short days triggers immune system enhancements in mice, which last for approximately 20 weeks. The immune system returns to its non-enhanced status after 32 weeks, even if short days remain. Melatonin levels are believed to play a key role in this process.
This study provides evidence for pathogen-specific gene responses in dendritic cells, offering insights into the tailored immune defense mechanism. The research uses DNA array technology to investigate how dendritic cells discriminate between pathogens and activates specific genes to initiate an immune response.
SourceWhitehead Institute for Biomedical Research·JournalScience·DateOct 25, 2001
Prostate cancer screening is a contentious issue due to its potential impact on quality of life and the need for well-informed decision-making. The article highlights the limitations of current research, including the lack of data on risk-benefit analysis and the importance of avoiding unnecessary anxiety and treatment.
SourceECCO-the European CanCer Organisation·DateOct 25, 2001
The 2002 OlympiYeda science competition brings together students from the US, Canada, England, and Australia to explore advanced police investigative techniques. Students will analyze forensics, DNA, and other disciplines to solve real-world cases.
SourceAmerican Friends of the Israel National Museum of Science·DateOct 25, 2001
Researchers found that an egg phospholipid interferes with cholesterol absorption in the intestine, lowering its uptake by the intestine. This may explain why some studies have found no association between egg intake and blood cholesterol levels.
SourceKansas State University·JournalJournal of Nutrition·DateOct 25, 2001
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Researchers found that the number of affected relatives is a stronger predictor of breast cancer risk than the age at diagnosis. Women with one or two affected relatives have significantly higher lifetime incidence rates (7.8% and 13.3%, respectively), while those with three affected relatives face the highest risk (21.1%).
A quadruplet pregnancy resulted from IVF and spontaneous conception, highlighting the risks associated with unprotected intercourse during ovarian stimulation. The woman gave birth to a boy and two girls with separate placentas and another girl with fused placenta after undergoing multiple pregnancies were deemed medically undesirable.
SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·DateOct 25, 2001
The Nenana Ice Classic provides a consistent and accurate dataset on river ice breakup timing, showing spring is coming earlier due to climate change. Researchers can use this historical record to analyze the effects of global warming on natural systems.
Researchers discovered that insulin sensitivity decreases by 32% among pubertal teens, while those who haven't started puberty experience increased sensitivity. The study suggests that changes during puberty contribute to lowered insulin sensitivity, with potential implications for preventing type 2 diabetes.
SourceUniversity of Southern California·JournalDiabetes·DateOct 25, 2001
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Researchers found that introducing charges for breast-cancer screening reduced attendance rates, particularly among younger women. In Turku, Finland, the introduction of a fee sent a message to the female population questioning regular mammography screening.
A new study from the United Nations Food and Agricultural Organization and Mayo Clinic found that women in western Africa need more energy than men based on their work burden. The research determined that women worked two to three hours more per day than men, resulting in a 30% increase in energy needs.
Research finds HR practices enhance financial performance in British businesses, particularly in manufacturing sector. Companies with specialist personnel relations demonstrate strongest and most consistent association between profit and people management.
Researchers have found fossil skulls and partial skeletons of the giant Sarcosuchus imperator, which lived during the African Cretaceous period. The species is estimated to have reached its full size in around 50-60 years, suggesting a unique growth pattern that allowed it to attain massive proportions.
SourceAmerican Association for the Advancement of Science (AAAS)·JournalScience·DateOct 25, 2001
The HCRC combines faculty members, students, facilities, and expertise from several Virginia institutions to develop effective management strategies for horseshoe crabs. Researchers are conducting studies on population changes, biomedical industry impact, and shorebird interactions to inform conservation efforts.
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The Fugu genome project has sequenced the entire genome of pufferfish using a whole-genome shotgun strategy, revealing approximately 365 million bases of genetic material. This will aid in identifying genes and regulatory sequences in the human genome, offering new insights into its structure.
SourceDOE/Lawrence Berkeley National Laboratory·DateOct 25, 2001
The EU's database protection law could limit access to information, hindering scientific progress and innovation. The US Congress should consider the potential impact on trade and the economy before passing similar legislation.
Researchers have identified a new class of microRNAs in the roundworm C. elegans, which are tiny regulatory RNAs that can regulate gene expression without producing proteins. The study found dozens of these genes, including two that are also present in humans and could play a role in heart tissue development.
SourceThe Geisel School of Medicine at Dartmouth·JournalScience·DateOct 25, 2001
The Declaration of Helsinki 2000 has been criticized for its inadequate revision process, with only 2 weeks available for comment and critique. Key changes include guidance on monitoring and oversight, but also deficiencies in assessing risks and ambiguous wording that may affect application.
A study of severely obese children found abnormalities in their arteries, including stiffness and reduced elasticity, linked to heart disease and strokes. The authors warn that childhood obesity is a growing concern, translating to increased cardiovascular morbidity and mortality if left unchecked.
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Researchers report a successful heroin-assisted treatment programme that reduces infections, mental disorders, and crime among chronically addicted heroin addicts. The six-year study found 86% of patients remained in the programme for three months, with improved social functioning and reduced illicit drug use.
Johns Hopkins faculty members Kay Redfield Jamison and Geraldine Seydoux have been awarded the MacArthur Foundation's 'genius' award for their innovative research in psychology and biology. Their work has significantly advanced understanding of mental health treatment, psychiatric disorders, and biological development.
Introgen's gene drug demonstrates tumor growth control by targeting the mda-7 gene, a key tumor suppressor. The study shows that replacing the mda-7 function in cancer cells can stop tumor growth and is promising for treating advanced melanoma.
SourcePorter Novelli·JournalInternational Journal of Cancer·DateOct 25, 2001
Researcher David Tilman's study found that mixing multiple plant species leads to higher productivity, as each species brings unique traits for resource utilization. This principle can benefit various ecosystems, including forests and fisheries, by promoting a more diverse range of organisms.
SourceUniversity of Minnesota·JournalScience·DateOct 25, 2001
Screening for colorectal cancer could lead to a 20% reduction in mortality rates, but its effectiveness depends on various factors. The UK government has set up pilot centres to evaluate the potential of faecal occult blood testing (FOBT) as a screening method.
SourceECCO-the European CanCer Organisation·DateOct 25, 2001
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Researchers developed a new algorithm called TwoDay, which uses vaginal dampness as a predictor of fertility. Women can reduce pregnancy risk by avoiding unprotected sex for 2 days after noticing vaginal dampness.
SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·DateOct 25, 2001
Physicists at Rice University have discovered a new class of critical point that marks a substantial advance in the study of phase transitions. They found that under suitable conditions, quantum critical metals contain 'critical local excitations' with very low energy, which could be applicable to a range of strongly correlated metals.
Researchers found that women taking oral contraceptives showed no change in their ability to detect odors, compared to the natural clime of the luteal phase. The study suggests that iatrogenic steroids may affect changes in smell sensitivity, and further research is needed to investigate this phenomenon.
SourceEuropean Society of Human Reproduction and Embryology·JournalHuman Reproduction·DateOct 25, 2001
Researchers aim to better understand cellular immunity in fighting Alzheimer's disease using a new mouse model jointly developed by USF and the University of Pennsylvania.
SourceUniversity of South Florida (USF Health)·DateOct 25, 2001