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Science News for November 15, 2002


Assisted reproduction may be linked to birth defect syndrome

Researchers have found a possible association between IVF and an increased risk of Beckwith-Wiedemann syndrome (BWS), a genetic disorder that can predispose children to cancer. BWS is characterized by excessive growth and occurs in about 1 in 15,000 births, with the incidence being significantly higher among IVF-conceived babies.

SourceJohns Hopkins Medicine·JournalAmerican Journal of Human Genetics·DateNov 15, 2002

New genetic option for thwarting cancer

Researchers have discovered a new genetic mechanism to prevent cancer development by targeting the Cdk4 gene. The study showed that knocking out this gene can make cells resistant to cancer even if their tumor suppressor defense is deficient. Cells then enter senescence, offering a promising new option for cancer therapy.

SourceUniversity of Illinois Chicago·JournalGenes & Development·DateNov 15, 2002