A recent study found that ethanol exposure increases tumor size, blood vessel density, and VEGF levels in chick embryos, supporting the hypothesis that ethanol-induced angiogenesis contributes to cancer progression. The study provides new insights into the mechanisms underlying alcohol's association with various types of cancer.
Geologists have discovered evidence of massive ice-dammed lakes in the Himalayas, which burst and caused catastrophic floods. The discovery provides new insights into the geological history of the region and its impact on the surrounding landscape.
Bruce Danyluk, a Williams College computer science professor, has won an award for his significant contributions to computer science education. He is recognized for designing and implementing the college's computer science major and department, as well as developing national computer science curricula.
Researchers at Illinois have developed a new class of biological sensors using single-walled carbon nanotubes. These sensors can detect glucose concentrations in human tissue, providing potential applications for diabetes management and other medical conditions.
A four-year study by Yale researchers found that vaccinating white-footed mice reduced the number of deer ticks carrying Lyme disease. The study demonstrated a significant reduction in risk for humans getting Lyme disease from tick bites, but not as great as expected. Further development of oral vaccines is proposed to reduce human risk.
Researchers discover how the hepatitis virus's X protein influences liver cell behavior, potentially leading to alternative cancer therapies. The protein's presence in patients' livers could be harnessed to target only cancerous cells.
A new study predicts that up to 14% of all bird species will be extinct by 2100, leading to a decline in forest ecosystems and agriculture worldwide. This dramatic loss may also encourage the spread of human diseases and negatively impact ecosystem processes such as decomposition, pollination, and seed dispersal.
A recent study at Yale University found that the ADHD medication Ritalin has a comparable impact on adolescents with reading disorder, improving brain activity levels. The research used functional magnetic resonance imaging to analyze brain function and revealed altered areas of activation in response to cognitive tasks.
Researchers discovered that constant light causes visual impairment through a separate mechanism from retinal degeneration. A decline in rhodopsin concentration leads to blindness, and inhibiting its degradation may reduce the severity of visual impairment.
A Stanford study analyzed 40 ads for body scans and found that virtually none presented a balanced picture. The researchers recommend guidelines requiring more detailed information to be available to consumers, who are capable of being savvy consumers of medical technology.
Researchers identified phenolic compounds in pine bark extract with high biological activity, including potent inhibition of nitric oxide and prostaglandin production. The study suggests that consuming pine bark-based food supplements may help alleviate arthritis symptoms.
A University of Colorado at Boulder research team has discovered evidence of microbial activity in a rock glacier, a barren environment previously thought to be devoid of life. The discovery includes traces of dissolved organic material and high levels of nitrates, suggesting microbes metabolize nitrogen within the glacier.
A new camera system and software may reveal clues about how ocean currents affect erosion, as well as near-shore phenomena like rip currents. The findings suggest a more complicated picture of water movement than previously thought, requiring researchers to re-examine ideas about beach erosion and repair strategies.
A study found that cancer patients receiving long-term bisphosphonate therapy were at risk of developing jawbone necrosis, a condition that can lead to bone death and require surgery. The condition is often associated with tooth extractions or other major dental work while on the drugs.
A new method automatically extracts acknowledgments of funding agencies, institutions, and individuals in computer and information science papers. The study finds NSF leads in citations, while DARPA funds established researchers with high impact work.
Researchers found that a protein called STAT3 is crucial for the development of psoriasis and can be reversed with a specific treatment. The study's findings offer a potential new target for medications to relieve symptoms of psoriasis.
A study of 1,518 older adults reveals that cumulative trauma across adulthood can worsen health in later years, particularly for those experiencing traumatic events between 18-30 and 31-64 years. Researchers found that younger adults were more affected by adult trauma than childhood adversity.
Researchers at Stanford University have solved part of the puzzle on how Botox works by binding to specific sites on proteins called SNAREs, preventing muscle contraction and paralysis. The study could help develop alternative treatments for botulism and find new medical applications for Botox and other neurotoxins.
Scientists have identified a key mechanism by which botulinum neurotoxin recognizes and attacks specific nerve cell proteins. The discovery reveals an extensive interaction between the toxin and its target, known as exosites, enabling high specificity.
A recent study published at the ACNP Conference found that exposing rats to Ritalin during early development can lead to reduced ability to experience pleasure and reward, as well as depressive-like behaviors in adulthood. This raises concerns about the long-term effects of ADHD medication on normal-functioning brains.
Researchers developed molecular sheaths around carbon nanotubes to respond to glucose, detecting it with near-infrared fluorescence. The technique allows for real-time monitoring of blood glucose levels with long-term monitoring applications.
Scientists developed simple, physics-based equations to address limitations of current cloud formation methods. A new instrument measures conditions needed for a particle to become a cloud droplet, helping determine how emissions affect cloud formation.
Research reveals that waiting increases consumption enjoyment for indulgent treats like chocolate, but decreases anticipation for non-pleasurable items. Consumers who wait longer tend to experience more satisfaction upon actual consumption.
A recent study published in Proceedings of the National Academy of Sciences reveals that the brain can be retrained to process sound in an alternative way, allowing for improved hearing sensitivity. This new system enables neurons to selectively fire at specific volume levels, making it more responsive to subtle changes in loudness.
A population-based study of nearly 2,300 US adults found a significant link between gastrointestinal disorders and insomnia. The study suggests that irritable bowel syndrome is more common among people with sleep disturbances than those without.
A new study by Fox Chase Cancer Center finds that a shortened course of radiation therapy for women after lumpectomy may be a viable alternative to traditional six-week treatments. The four-week treatment schedule showed comparable skin toxicity levels to longer courses, with most side effects resolving within six weeks.
A large phase III trial showed that sequential treatment with ELLENCE delivered superior disease-free and overall survival compared to FEC 100 alone. The sequential regimen resulted in a 17% reduction in relapse risk and a 23% reduction in mortality risk.
The phosphatidylinositol 3 kinase (PI3K) pathway is crucial in breast cancer development, with aberrant levels and mutations affecting critical growth factor receptors. Researchers believe targeting central nodes in this pathway can effectively treat the disease.
A recent study found that individuals exposed to high levels of lead are more likely to develop cataracts, with bone lead levels being the best predictor. The researchers estimate that lead exposure plays a role in approximately 42 percent of all cataracts in the studied population.
A study published in the Journal of Consumer Research found that past experience significantly impacts consumer decision-making, with thoughtful individuals relying on context to inform their choices. Non-thoughtful individuals, however, are aware of trade-off values but fail to utilize this information when making subsequent decisions.
Researchers found a three-fold increase in suicide rates in two Salisbury, N.C., neighborhoods downwind of an asphalt terminal. Hydrogen sulfide levels were significantly higher than the World Health Organization's recommended standard, and exposure to other neurotoxic compounds may also be contributing factors.
Researchers found that celecoxib reduced estrogen receptor expression by an average of 9% after six months of treatment. This finding confirms celecoxib's antiproliferative properties and suggests a new potential therapeutic approach for breast cancer prevention.
A recent re-analysis of large clinical trials found that chemotherapy significantly improves survival rates in patients with ER-negative tumors, reducing the risk of death by 56 percent. The study suggests that chemotherapy has a greater impact on ER-negative patients than previously thought.
A new molecular test uses a panel of genes to predict the risk of breast cancer recurrence and identify patients who will benefit from chemotherapy. The test shows that women with low risk of recurrence do not derive much benefit from chemotherapy, while those with high risk have a large benefit.
A new immunosuppression protocol has significantly reduced the need for anti-rejection medications in intestinal transplant patients, resulting in a 96% one-year survival rate. The study showed that 69% of patients are taking a single dose of immunosuppression, and none experienced chronic rejection.
A unique study examines how African-American consumers use shopping to express their political beliefs in a time when traditional forms of participation are decreasing. The research highlights the importance of considering consumer politics in understanding social and political relations.
Researchers recreated extreme conditions to find that rocks rich in chromium minerals accelerate the production of more complex hydrocarbons. This process may help explain the diverse communities thriving around hydrothermal vents.
A recent study by the University of Alberta found that melatonin supplements have little to no benefit for individuals suffering from sleep disorders or experiencing jet lag. While some people may fall asleep sooner with melatonin supplementation, its effects on overall sleep quality are minimal.
Researchers at Scripps Institution of Oceanography have cloned a gene from the marine invertebrate Bugula neritina, which may prove key in developing new cancer drugs. The cloned gene, bryA, is thought to be involved in the production of bryostatin, a family of chemical compounds with potential as anticancer pharmaceuticals.
A study published in The Lancet found an underlying autoimmune process linked to narcolepsy in people with a certain genetic profile. This breakthrough could lead to improved disease treatment and earlier diagnosis using a clinically useful assay.
A nuclear-powered space mission to Neptune, expected to launch between 2016 and 2018, aims to gather data on the planet's atmosphere and its largest moon Triton. The mission will employ electrical and optical sensors to study Neptune's atmospheric elemental ratios, gravity, and magnetic fields.
Researchers found that nanotubes were ingested by white blood cells and retained their fluorescent properties, allowing for selective detection. The discovery builds on a previous finding of unique fluorescent signatures from individual types of nanotubes.
The patientINFORM consortium, led by commercial giants Elsevier, Springer, and Wiley, has sparked controversy among advocates for enhanced public access to research. While the proposal aims to make taxpayer-funded research available, critics argue it discriminates among illnesses without justification and fails to respect all patients'...
The Life Sciences Research Office review of scientific literature concludes that dental amalgam does not cause serious adverse health consequences, except in rare cases of allergic reactions. The study's findings contradict claims that mercury release from dental amalgam leads to various health issues.
Researchers at Thomas Jefferson University have developed a method to detect cancer gene activity outside the body, which could lead to earlier detection and treatment of breast cancer. The technique uses genetic probes to visualize sites of cancer gene activity, allowing for potential early diagnosis and targeted treatment.
Researchers at the University of Minnesota have developed a computational model of addiction that connects learning theories with neurophysiological mechanisms. The model uses temporal-difference reinforcement learning to simulate how addictive drugs impact brain function and behavior.
A new study contradicts previous predictions that coral reefs will suffer large declines by 2100 due to ocean warming. Instead, the research finds that coral reef calcification rates may increase by up to 35% by 2100, potentially exceeding pre-industrial levels.
Researchers at Berkeley Lab have produced atomic-resolution images of silicon nitride ceramics, revealing the exact location of rare-earth atoms and their effect on toughness. This discovery could lead to tailoring grain boundaries for optimum mechanical properties.
A new typeface called Clearview has been approved by the Federal Highway Administration (FHWA) for use on public roads in the US and Canada. The Clearview typeface offers a 20% improvement in legibility and recognition with the same size sign as currently used, reducing driver confusion and increasing safety.
Researchers found that people who believed they had become sick from eating hard-boiled eggs or pickles were more likely to avoid these foods in the future. However, the effect was limited to novel food items, with no change in behavior towards commonly consumed foods like potato chips.
Researchers detected continuous tremors near Cholame, 15 miles southeast of Parkfield, which are similar to those discovered in Japan and the Pacific Northwest. The tremors, which last more than four minutes each, may be precursory to earthquakes, potentially leading to earthquake forecasting and prediction.
Researchers found that males are more attracted to subordinate partners for high-investment activities like marriage and dating. The study suggests an evolutionary advantage for males who prefer less accomplished partners.
Researchers identified a subset of proteins vital to malaria parasite's survival in host red blood cells and a unique mechanism for protein export. This discovery allows for focus on key proteins for developing antimalarial drugs.
Scientists at Northwestern University have identified a signal on exported parasite proteins that enables the malaria parasite to target red blood cells. This discovery provides a new understanding of the complex mechanisms underlying malaria infection and offers promising leads for developing new treatments.
R207910, a novel diarylquinoline compound, has demonstrated effectiveness in clearing infection from lungs of mice and reducing bacterial load by 50%. The drug's unique mechanism of action targeting ATP synthase makes it active against drug-resistant strains of TB.
A NIAID-sponsored clinical trial is enrolling healthy adults to assess the immune response and safety of the Fluarix vaccine, which has been distributed in over 70 countries. The trial will provide valuable information on the vaccine's efficacy before it can be licensed for use in the US.
Researchers at the University of Michigan have discovered a compound that suppresses cell growth in psoriasis models, offering new hope for treating this life-long genetic condition. The compound, benzodiazepine-423, is selectively applied topically and shows great potential for controlling disease progression.
Researchers develop gene therapy to treat XP, a devastating disease causing cancerous lesions on exposed skin. The treatment restores DNA repair mechanism, preventing cancerous growth and sunburn-like symptoms in mice.
Researchers have discovered that neural crest stem cells in human hair follicles can differentiate into various cell types, including neurons and cartilage/bone cells. These findings hold promise for treating conditions such as Parkinson's disease, spinal cord injury, and bone degeneration.
A new antibiotic shows promise in treating tuberculosis by shortening treatment time and fighting drug-resistant strains. The drug, called R207910, operates differently than other antibiotics and appears to inhibit the bacteria's energy supply.