Scientists attribute high frequency of CCR5-Ä32 mutation in Scandinavia and Russia to protection from lethal, viral haemorrhagic fevers that occurred during the Middle Ages. The disease provided selection pressure for the mutation, which explains its highest frequency in these regions today.
Researchers have identified a gene mutation in Complement Factor H as a key factor in the development of age-related macular degeneration. This complex disease affects millions of Americans, with family history being a significant risk factor.
A statewide survey of coaches and students found that 40% of former tobacco users had oral lesions, with smokeless tobacco users at higher risk. Tobacco use is more prevalent among male athletes, particularly Caucasians, and increases from grade 6 to 22.7% by grade 12.
The study examines lessons learned from Africa's first public ARV treatment clinic in Botswana, highlighting the need for consistent care and ongoing training for staff. The clinic has successfully treated thousands of patients, but challenges persist in staffing and infrastructure.
A new tumor-suppressor gene called mats has been discovered by researchers at Penn State, which works with another tumor suppressor to control tissue growth. The study found that the mats gene can shrink tumors in flies and may regulate cell number and tissue growth by restricting cell proliferation.
Researchers at Duke University have identified specific DNA regions in yeast that are prone to breakage, mimicking cancer cells' chromosomal instability. By slowing down DNA replication, they found that certain retrotransposon sites become more susceptible to kink formation and rearrangements.
Research highlights oral health disparities across socio-economic status, race, gender, and age groups. Assessments of oral health, environment, behavior, microbiology, and genes within the family are key to improving access.
Increasing aircraft cabin ventilation can reduce disease transmission in-flight, with proper ventilation removing 63% of airborne organisms. Air travellers should prioritize good hand hygiene to prevent infection risk.
Researchers found that inhibiting SCD1 decreased body fat and prevented obesity and metabolic syndrome in mice. Blocking SCD1 also increased expression of genes involved in energy expenditure, providing insights into its role in metabolism.
A study published in Michigan Medicine found that women are less likely to receive quality heart attack care compared to men, despite experiencing the same mortality benefits. However, when given a one-on-one session with doctors or nurses and signing a discharge contract, women's survival rates improved significantly.
The Cassini Imaging Team report on Titan reveals that the moon's winds blow faster than its surface rotates, with speeds of up to 34 meters per second. The discovery suggests that meteorology works similarly on slowly rotating planets like Venus.
Researchers improved hurricane prediction using high-resolution general circulation models, predicting the course of four storms with increased accuracy. A new study found that solar emissions likely control Jupiter's X-ray emissions, providing a potential proxy for monitoring flares invisible to space weather satellites.
A new study found that emergency use of clopidogrel could reduce the risk of death and repeat heart attacks by up to 10%, without increasing serious bleeds. However, early treatment with metoprolol may increase the risk of cardiac shock, and its benefits tend to cancel out those of clopidogrel.
Researchers from the Forsyth Institute and University of Texas Health Science Center at San Antonio describe successful experiments in bioengineering mineralized tissues, including periodontal tissues and replacement tooth phenotypes. This breakthrough is supported by the National Institute of Dental and Craniofacial Research.
John Corbett, a renowned chemist, has been awarded the Spedding Award for his outstanding contributions to inorganic solid-state chemistry and strong metal-metal bonding. He is the third Ames Laboratory researcher to receive this honor.
Dr. Moore's distinguished career has led to evidence-based frameworks for clinical dentistry, with notable contributions in pediatric sedation guidelines and diabetes research. His work has provided a foundation for optimal pain control and minimal adverse effects in clinical analgesics and anesthetics.
Researchers use microspectrometry to map the unique color patterns of individual gems, revealing differences even among same-type stones. This technique could provide valuable information for gemstone authentication and potential recovery of stolen stones.
A new chemotherapy combination has shown significant improvement in survival rates for brain tumour patients, with almost half of those with an inactivated MGMT gene surviving after 2 years. The treatment also did not negatively impact patients' quality of life, offering a promising breakthrough in glioblastoma treatment.
Dr. Kato's research focuses on practical clinical issues affecting the general public, including tooth-grinding which can cause sensitivity and pain. He is one of 15 recipients to receive the IADR Young Investigator Award annually, recognized for his basic research in dental disciplines.
Dr. Castle's work elucidates the mechanism of secretion from exocrine cells, particularly salivary glands, through analysis of secretory granules and membrane components. His discovery of SCAMPs and demonstration of four pathways of secretion in parotid cells contribute to a deeper understanding of membrane trafficking and exocytosis.
Dr. MacDougall receives the IADR Basic Research in Biological Mineralization Award for her groundbreaking research on tooth formation and tissue-specific gene regulation. Her work has been funded continuously since 1985 by the NIH/NIDCR.
The High-Altitude Particle Experiment Aircraft (HIAPER) is a modified Gulfstream V jet that can fly up to 51,000 feet and cover 7,000 miles. With its advanced capabilities, HIAPER will allow scientists to study atmospheric processes, environmental phenomena, and interactions between oceans and atmosphere.
Researchers at UC Berkeley have discovered three overlapping signals in the embryo that are crucial for proper development of the backbone and belly. By blocking these signals, the team found that tissues form on the back were lost while belly tissues were greatly expanded, leading to a repatterning of the entire embryo.
Dr. Meurman's research on the role of oral infections in medically compromised patients has significant implications for geriatric populations. The 2005 Geriatric Oral Research Award recognizes his contributions to the field, including advancements in molecular biological techniques for detecting oral pathogens.
The IADR Distinguished Service Award was presented to Tom Lehner for outstanding service to the Association. The E.W. Borrow Memorial Award was given to George Stookey for his research on oral health prevention, and several fellowships were awarded to support young researchers in dental sciences.
Researchers have solved the structure of an essential RNA domain in telomerase, a crucial enzyme in cancer cell division. The discovery provides insights into how telomerase works and could lead to targeted drug interventions.
Researchers found that people mentally fill in gaps in familiar music with auditory imagery, and lyrics impact different auditory brain regions when reconstructing musical memories. The study extends previous work on auditory imagery and visual imagery, revealing a kind of auditory imagery typical of everyday experience.
Researchers have discovered evidence of barren ground grizzly bears on Melville Island, a remote area in the western Arctic. The presence of these bears is significant as they are known to prey on polar bear cubs and could potentially disrupt the balance of Arctic ecosystems.
A study examining Thailand's 'war on drugs' found that rural communities had a greater impact than urban centers, with 78% of rural users quitting injecting drugs. Despite the strictness of the policy, 85% of participants believed it was 'good', possibly due to its deterrent effect on others.
Dr. Eliades received the 2005 Wilmer Souder Award for his groundbreaking research on dental biomaterials surface analysis, including spectroscopic and electron optical methods. His work has advanced significant dental health through understanding molecular interactions and conformational changes of collagen with dentin-bonding agents.
Charles Townes, 89, won the 2005 Templeton Prize for his investigations into microwave properties and co-invention of the laser. His research has led to numerous inventions and discoveries in medicine, telecommunications, and other areas.
Researchers have discovered that a meteorite traveling at a slower velocity than previously thought formed Meteor Crater. The study reveals that atmospheric drag slowed down the fragments, causing them to crumble and slow more, resulting in little to no melting of the surrounding rocks.
Researchers at the University of Utah Health have created a genetically engineered mouse model that closely mimics age-related macular degeneration and Stargardt disease. The study provides a promising platform for testing treatment strategies such as cell transplantation, gene therapy, and pharmaceuticals.
Researchers have successfully treated an animal model of alpha-mannosidosis, a rare genetic disorder that causes severe mental retardation and skeletal abnormalities, with gene therapy. The treatment restored damaged neurons and improved brain function in cats with the disease.
Dr. Hausen receives the IADR Distinguished Scientist Award for his pioneering work in Community Dentistry and caries risk assessment prevention. His research has inspired junior faculty members and influenced public oral health policies in Finland and beyond.
Researchers have found that Canada's Arctic ice caps and glaciers are thinning at lower elevations due to increased melting. The study suggests that these changes contribute significantly to global sea level rise, with an estimated 0.065 millimeters per year added to sea levels during the 1995-2000 period.
Researchers developed a new scale to predict recovery of consciousness from coma after brain injury. The Disorders of Consciousness Scale (DOCS) accurately detected improvements, declines, and plateaus in neurobehavioral functioning.
Dr. Somerman received the award for her outstanding contributions to oral biology research, recognized as the Association's highest honor. The IADR Research in Oral Biology Distinguished Scientist Award is one of 15 bestowed annually by the IADR.
Dr. Rozier has made significant contributions to dental public health, developing methods and findings to improve basic public health core functions and access to dental care for disadvantaged populations. He also conducted research on effective public health interventions to promote oral health and prevent dental diseases.
Dr Hylander's pioneering research on mandible mechanics and jaw joint loading has significantly advanced the field of craniofacial biology. His work has been widely applied and recognized with awards including the NIH Merit Award.
A study by Duke University researchers found that moderate inhalation anesthetic exposure during pregnancy may not be deleterious to the fetus. The exposure improved cerebral oxygenation in the developing fetus, suggesting a potential benefit for pregnant women undergoing general anesthesia.
Dr. Curtis has received the Basic Research in Periodontal Disease Award for his outstanding contributions to understanding bacterial protease function and glycosylation of bacterial virulence determinants. The award recognizes his work in developing novel antimicrobial strategies against periodontal pathogens.
Professor Johnson is awarded the IADR Oral Medicine and Pathology Research Award for his significant contributions to dental caries, periodontal diseases, and oral cancer research. He has also made a notable impact on oral cancer prevention through his advocacy.
Professor Kidd's extensive research has significantly impacted the development of early caries detection methods and treatment planning. Her work has been instrumental in shaping best practices for treating dental caries, with a focus on practical clinical applications.
Professor Magloire has made significant contributions to odontoblast biology, including characterizing replacement populations and developing novel culture systems. His research has shown the role of TGFβ and new gene profiles involved in odontoblast differentiation and mechanosensitivity.
Researchers at NYU and MSKCC have discovered a conformational switch in DNA that changes the way carcinogens bind to p53 genes, potentially leading to cancer. The study sheds light on how environmental chemical carcinogens, including those found in cigarette smoke, can induce mutations and cancer.
The Cassini mission has captured high-resolution images of Titan, revealing a geologically young surface with signs of tectonic resurfacing and erosion by liquid hydrocarbons. The surface features complex patterns, including channels and linear boundaries, indicating ongoing geological processes.
Forensic bite-mark matching has been criticized due to its fallibility and distortion problems. A new approach using 3D imaging has shown promise in improving accuracy, but with a 15% chance of incorrect matches. The technology could be useful in courtrooms for illustrating the likelihood of a match.
The Research in Prosthodontics and Implants Award honors Dr. Naert's contributions to prosthodontics through his extensive clinical studies and biomechanical analysis. His work has significantly impacted the practice of implant dentistry.
A new study by Stanford University scientists presents direct evidence linking large-scale coastal farming to massive algal blooms in the sea. Highly productive regions of the ocean are found to be more vulnerable to agricultural runoff than assumed.
The American Physiological Society has awarded young investigators in various fields of physiological research, including respiratory physiology and epithelial renal physiology. These awards recognize outstanding promise in the field and support research that could lead to advances in stem cell therapy and gene treatment.
A study by Washington University researchers found that husbands' education levels have a greater impact on migration patterns than wives', with power couples more likely to move to large cities. The study suggests that women can expect ongoing disparities in professional salaries, as the continued presence of trailing wives contribute...
The 'Dig Manchester' project has seen the community come together to uncover history, with businesses donating goods in kind and a sense of community pride emerging. The three-year programme will also involve similar projects in Northenden and Wythenshawe, aiming to promote local heritage and regeneration.
Researchers found that P putida can transform mustard by-product toxins, decreasing their levels by up to 83%. This biotechnological method offers maximum environmental safety by degrading pollutants into harmless products. The bacteria strain could be used in plant-microbial associations for future remediation of contaminated soils.
Scientists at PNNL discovered that micron-wide dust particles encrusted with molecularly gluey ice enabled planets to bulk up quickly enough to overcome solar winds. Fluffy ice provided a cushioning effect, allowing icy grains to stick together and grow into large lumps.
A Phase IIb trial found that VEGF-2 therapy led to significant improvements in exercise tolerance time and reduction in angina symptoms. The study suggests that the therapy may be associated with prolonged clinical benefits for patients with severe angina.
A new study suggests that PET scanning is more accurate than SPECT in detecting heart disease, leading to a significant decrease in the use of invasive procedures like angiograms and bypass surgery. This could result in cost savings of up to 25% for patients managed with PET scanning.
Children with Progeria have lower levels of HDL cholesterol and adiponectin, contributing to accelerated plaque formation. The study aims to better understand atherosclerosis in the aging population and find treatments for this rare genetic disorder.
A University of Pennsylvania study identified 22 ways in which CPOE systems facilitate medication errors, including information errors and human-machine interface flaws. The researchers recommend that institutions focus on the organization of work within the hospital and continuously evaluate and improve their technology.
A recent Emory University study found that HIV infection is not an independent risk factor for severe heart disease in patients who undergo cardiac catheterization. Lifestyle and traditional cardiac risk factors, such as hypertension and high cholesterol levels, play a larger role in the development of CAD.