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Science News for January 14, 2005


Mitochondrial DNA mutations play significant role in prostate cancer

Researchers found mitochondrial DNA mutations in 12% of prostate cancer samples and 7.8% of general population controls, with increased tumor growth and oxygen radical production in mutant cells. These findings suggest a causal link between mtDNA mutations and prostate cancer development, particularly in African men.

SourceEmory University Health Sciences Center·JournalProceedings of the National Academy of Sciences·DateJan 14, 2005

NYU researchers simulate molecular biological clock

Researchers at NYU developed a mathematical model that replicates the complex network of molecular interactions within a cell's circadian clock. The study found that rapid binding and unbinding of regulatory molecules is crucial for accurate timekeeping, contradicting the notion that more molecules lead to better accuracy.

SourceNew York University·JournalProceedings of the National Academy of Sciences·DateJan 14, 2005