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Science News for May 30, 2005


Sickle cell and protection against malaria

Researchers have found that carrying the sickle cell gene provides partial protection against malaria, increasing to 60% in childhood before declining. The study suggests an immune component to this protection and may offer insights into developing an effective vaccine.

SourcePLOS·JournalPLOS Medicine·DateMay 30, 2005

Longevity controlled by calorie quality, not quantity

Researchers found that reducing yeast in flies' diet increased life span by over 60%, suggesting protein or fat plays a greater role in longevity than sugar. The study's findings challenge the conventional wisdom that eating less promotes longevity and provide insight into the effects of different nutrients on life span.

SourcePLOS·JournalPLOS Medicine·DateMay 30, 2005

In those genetically predisposed, 'developmental reprogramming' could explain cancer risk

A study published in PNAS found that prenatal exposure to diethylstilbestrol (DES) can permanently alter tissue in rats, making them more susceptible to hormone-dependent tumors. The researchers believe this phenomenon could explain why some people with inherited tumor suppressor gene defects develop cancer while others do not.

SourceUniversity of Texas M. D. Anderson Cancer Center·JournalProceedings of the National Academy of Sciences·DateMay 30, 2005