Researchers have developed a new technique to detect malaria infection in human blood using lasers and non-linear optical effects, eliminating the need for slides and microscopes. The technique holds promise for simpler, faster, and labor-intensive detection of the malaria parasite.
A recent study has uncovered a link between genetic variation and extreme body mass, suggesting that synonymous SNPs may affect mRNA splicing. The findings imply that subtle changes in genes involved in metabolism could lead to visible phenotypes later in life.
Researchers at Weill Cornell Medical College have identified the role of Synaptojanin 1 in the synaptic vesicle cycle, a critical aspect of synaptic function. The enzyme's removal slows down endocytosis, highlighting its importance in cell-to-cell information flow.
A Virginia Tech chemist has developed a computational method to determine the handedness of chiral molecules, which could speed up drug development. This technique eliminates the need for synthesizing the two hands of chiral molecules, reducing time consumption by weeks or years.
Harvard researchers suggest sulfur dioxide played a crucial role in maintaining Mars' warmer climate between 3.5 and 4 billion years ago. The presence of sulfur dioxide would have prevented the formation of limestone deposits, leading to the absence of carbonate on Mars today.
Researchers propose new mechanism for superconductivity in materials without phonon interaction, potentially leading to higher temperatures. This discovery could pave the way for a new class of high-temperature superconductors.
Researchers found that antimalarial drug chloroquine effectively prevents cancer in mouse models of two distinct human cancer syndromes, Burkitt lymphoma and ataxia telangiectasia. Chloroquine inhibited the development of Myc-induced lymphomas and mediated its effects through autophagy and lysosomal stress.
A study at Cincinnati Children's Hospital Medical Center reveals that a protein recycling system failure may be linked to the development of certain diseases, such as cancer and heart disease, as well as birth defects. The Retromer Complex plays a critical role in delivering signaling proteins to tissue-building sites.
The team led by Maria Schumacher, Ph.D., produced clear 3-D images of the structure resulting from two proteins connecting with a DNA site to 'segregate' DNA during cell division. The solved structure provides fundamental insight into how cells divide with intact DNA.
Research on frogs and giraffes reveals three distinct species of terrestrial leaflitter frog and at least six genealogically distinct lineages of giraffe, highlighting underestimated biodiversity. The findings suggest that some subspecies have fewer than 100 members, making them highly endangered.
Researchers identified a critical role for the hormone adrenomedullin in forming the lymphatic system, which could lead to new treatments for lymphedema. Targeting this hormone may also prevent cancer cells from spreading through lymphatic vessels.
Bevacizumab plus interferon improves progression-free survival in patients with metastatic renal cell carcinoma compared to interferon alone. The new treatment option is expected to provide a better prognosis for patients with renal cancer.
The Surgilux device seals surgical wounds using an infrared laser, potentially reducing complications and infections associated with sutures. Early test results show promising results in brain and nerve surgery, paving the way for a new approach to repairing damaged nerves.
University of Michigan scientists have identified a previously unknown link in the biochemical reactions implicated in some forms of heart disease. The discovery provides a new target for future drug therapies and could potentially treat cardiovascular disease.
The Medical College of Georgia has been designated as a Minority-Based Community Clinical Oncology Program by the National Cancer Institute, receiving a five-year $2.3 million grant to expand access to latest cancer treatment and prevention strategies for minority patients.
A team of Chilean and IRD scientists found that the Pacific seaboard experienced significant cooling between 1820 and 1878 due to a large continent-ocean temperature contrast. This discovery sheds new light on El Niño's variability, which may intensify in a warming world.
A UCLA summit published in Molecular Ecology highlights the need for additional research on human-caused ecological changes. The study reveals that climate change is outpacing species' ability to adapt, leading to increased disease threats, reduced biodiversity and loss of natural heritage.
A new study reveals that large numbers of modern-day beetle lineages evolved soon after the first beetles originated and have persisted ever since. The team used DNA sequencing and fossil records to compile an evolutionary family tree for beetles, showing that many species pre-date the appearance of flowering plants.
Researchers developed a new wound dressing using hair follicular cells that increased wound closure rates by two times compared to control subjects. The technique provides an effective biodressing that maintains structural strength during healing, promising early-stage wound healing improvements.
Advances in genome sequencing and single-nucleotide polymorphisms have revealed the vast differences in human DNA, enabling researchers to identify disease-related genes and risk factors. The study also highlights the potential of 'copy number variants' and induced pluripotent stem cells to improve our understanding of genetic activity.
Astronomers discover triple merger of galaxies, dubbed 'The Bird', with ESO's VLT. The system reveals two massive spiral galaxies and a third irregular galaxy forming stars at high rates.
A recent study has linked lower mental health scores to an increased risk of major amputations in diabetic veterans. The research, published in General Hospital Psychiatry, suggests that addressing mental health functioning is crucial in preventing amputation risk.
A new study suggests that Thailand's Western Forest Complex can potentially support around 2,000 tigers, with an estimated 720 tigers currently inhabiting the area. Improved enforcement and safeguarding measures are crucial for making these numbers a reality and ensuring the long-term survival of this iconic species.
Researchers at the University of California, San Diego, have identified a unique plant gene that prevents fertilization when mutations are present in both the male and female reproductive cells. The discovery, known as 'abstinence by mutual consent,' reveals a previously unknown mechanism in plant reproduction.
Researchers have developed a new class of magnetic shape-memory foams with improved strain capabilities. The porous alloy's structure amplifies the shape-change effect, making it suitable for tiny motion control devices or biomedical pumps without moving parts.
Researchers outline the blood-brain barrier's role in neurological disorders, calling for more studies and resources to overcome delivery obstacles. They propose interdisciplinary collaborations to develop new therapies for diseases like Alzheimer's and multiple sclerosis.
Researchers have developed four unique human parthenogenetic stem cell lines that are HLA-homozygous, reducing the risk of provoking an immune reaction. These lines can serve as a renewable source of transplantable cells for treating genetic and degenerative diseases.
Researchers found that the antimalarial drug chloroquine effectively prevents cancer in mouse models of two human cancer syndromes, Burkitt lymphoma and ataxia telangiectasia. Chloroquine inhibited the development of Myc-induced lymphomas and ATM-deficient mice, but not p53-deficient mice.
A type of beetle that lives in stored grain has been found to lack full colour vision. The red flour beetle's compound eye retina lacks the blue-opsin encoding photoreceptors, violating the 'one receptor rule' of sensory cells. This adaptation may have provided an evolutionary advantage.
New research identifies a second gene, TRIM22, that exhibits rapid evolutionary adaptation to defeat retroviruses, suggesting alternate defense mechanisms over time. The study suggests that both TRIM5 and TRIM22 have played roles in protecting humans against retroviral infections.
Researchers found that erythropoietin administration can prevent acute cardiotoxic effects induced by chemotherapy agents doxorubicin and trastuzumab. The study suggests that rhEPO may be used to reduce acute cardiotoxic effects during chemotherapy, potentially preventing long-term development of cardiomyopathy.
Researchers explore how genes, neurotransmitters, and brain function impact athletic performance and endurance. Studies reveal that certain genetic variations and mental state can significantly enhance physical abilities.
While flavanol-rich dark chocolate offers cardiovascular benefits, manufacturers often remove these compounds to balance calorie content, rendering the product less healthy than claimed. Flavanols have antioxidant properties but are not a guarantee of healthiness.
A new study found that leptin can delay the onset of seizures in rodents, suggesting it may be a key player in how a ketogenic diet combats epilepsy. The authors propose dietary changes and intranasal administration of leptin as potential treatments.
A large study found that depression significantly worsens HIV treatment adherence and clinical measures, but antidepressant medication can improve outcomes. Depressed patients had lower adherence rates and worse viral therapy responses compared to non-depressed patients.
A new study funded by the Economic and Social Research Council found that there is little evidence of a 'cultural elite' that aspires to high culture while shunning popular culture. The research confirmed that education and social status are key factors in determining cultural consumption, with a significant proportion of people from a...
The Center for Maritime Systems at Stevens Institute of Technology has acquired three pieces of advanced research equipment with a $522,450 grant from the Defense University Research Instrumentation Program (DURIP). The CNC machine will be used to construct ship models and other hydrodynamic research equipment.
The new ecosystems approach to fishery regulation requires consideration of various uses of maritime resources and interactions between different sectors. The study highlights the need for interactive decision-making processes to promote versatile use of information about the maritime environment.
A University of Calgary biologist has made a groundbreaking discovery about geckos' ability to stick to surfaces using their unique toe pads. By studying the microscopic level of setae structures on gecko feet, researchers found that friction plays a crucial role in geckos' adhesion system.
A recent study suggests that changes in global carbon dioxide levels likely influenced the emergence of C4 grasses, a group of plants crucial for food and biofuels. The researchers found a correlation between the drop in CO2 levels 30 million years ago and the evolution of these grasses.
A study discovered three-finger toxins in a rare rattlesnake subspecies, while a novel toxin gene was found through gene fusion. This discovery reveals the complexity of snake venom composition and its potential for developing new therapeutic agents.
A four-year study found that walking and moderate exercise significantly lowered the risk of developing vascular dementia in people over 65. Participants who exerted more energy through physical activities like walking, gardening, or house work had a 27% lower risk compared to those with less energy expenditure.
A new approach to gene prediction, CONTRAST, leverages multiple genomes to identify protein-coding genes with high accuracy. The technique directly learns useful features from genomic alignments, leading to significant improvements over existing methods.
The National Fish and Wildlife Foundation has awarded a major grant to the Manomet Center for Conservation Sciences to support shorebird conservation programs. The Western Hemisphere Shorebird Reserve Network will conduct conservation activities at 68 sites in nine nations, with a focus on addressing declines in shorebird populations.
Soil samples from a forest ecosystem with artificially elevated CO2 levels reveal distinct changes in the mix of microorganisms living beneath trembling aspen trees. These changes support increased plant growth and the ability to sequester excess carbon.
A new study by UC Davis researchers found that the Loma Prieta fault exhibits more stresses and slip directions in its aftershocks than previously thought. The findings suggest a more complex deformation pattern, contradicting previous assessments of the fault's weakness.
Researchers developed a novel approach to gauge disease progress in adult T-cell lymphoma and leukemia, using firefly genes to detect cancer cells. The study found that combining PS-341 and zoledronic acid effectively killed 95% of ATLL cells, while also reducing bone resorption and calcium buildup.
The GLAST satellite, a gamma-ray telescope, has arrived at the Naval Research Laboratory in Washington for testing before its launch later in 2008. The mission will study extreme environments in the universe, identifying unknown sources of gamma rays.
A study found that certain types of tantrums, such as self-injurious behavior and violent aggression, are associated with clinical problems like depression and ADHD. Healthy children tend to have shorter, less aggressive tantrums.
A recent breath test can accurately detect SIBO by measuring hydrogen levels in expired air. The disorder has severe systemic consequences including sepsis and multiorgan failure if left untreated.
The Human Microbiome Project aims to understand the interactions between microorganisms and the human body, with potential applications for preventing, diagnosing, and treating diseases. The project will sequence microbial genomes from over 1,000 sources, including healthy volunteers and those with specific diseases.
The Journal of Human Capital is a new publication that explores the role of education, training, and knowledge in economic life. Key findings include the impact of household vs. marketplace rewards on education, as well as the effect of student loans on lower-income families' college options.
A seven-year study found that individuals who take time to reflect on their losses are more likely to mature and achieve a potentially more durable sense of happiness. Participants who acknowledged past loss showed personality development over time.
Researchers found that IETM is the arch-criminal in HPS development, leading to increased NO and CO production and vascular abnormalities. The study suggests that targeting LPS may be effective in preventing and treating HPS.
Researchers at UC Davis found that California ground squirrels and rock squirrels apply snake scent to themselves by picking up shed skin and licking their fur. This behavior helps mask the squirrel's own scent and deters snakes from attacking.
A new study by the New York City Health Department found that immigrant children are five times more likely to suffer from lead poisoning than U.S.-born children. The risk is highest among recent immigrants from countries with less stringent lead regulations, such as the Dominican Republic and Pakistan. To protect their children, paren...
Researchers at Weill Cornell Medical College have developed a new drug that blocks the live viral infection of Hendra and Nipah viruses, which are on the US government's list of potential threats. The peptide-based entry inhibitor has been proven effective in blocking the infection of live virus in animal cells.
A team of Japanese researchers found that premenstrual syndrome is tied to decreased nerve activity, particularly in those with extreme symptoms. Women with premenstrual dysphoric disorder had altered sympathovagal activity even in the follicular phase, suggesting a potential underlying biomechanism for PMS.
A new study from Harvard School of Public Health found an association between domestic violence and adult smoking among Indian women. The study suggests that domestic violence may act as a 'stress reliever' in households where it occurs, leading to increased tobacco use.
Researchers at UC Davis have determined the earliest stage of planet formation occurred approximately 4,568 million years ago. This finding provides new insights into the timing and physics of this critical process, shedding light on how mountain-sized chunks of rock coalesced from interstellar dust.