A recent study examined the discrepancy rate of emergency diagnostic imaging exams interpreted by residents after hours and found that well-trained and supervised residents can interpret studies safely. The major discrepancy rate was 2.6%, with only a miniscule negative clinical effect found in 0.3% cases.
Gina Turrigiano, a Brandeis University professor, has received a National Institutes of Health (NIH) Director's Pioneer Award to develop a super-resolution cryo-microscopic method for studying synapses. This innovative approach aims to understand how synapses are impaired by neurodevelopmental and neurological diseases.
Researchers found that hair follicles on the head have the potential to become erythropoietin factories, potentially treating EPO-related anemia. This discovery opens doors to a new approach for treating severe anemia associated with kidney failure and chemotherapy.
Exposure to particulate matter in mice triggers lung macrophages to produce IL-6, leading to accelerated blood clotting and thrombus formation. Targeting IL-6 may decrease the risk of heart problems caused by air pollution.
A team of researchers has determined that human ancestors outside of Africa were more primitive than previously thought, based on analysis of 1.8 million-year-old fossils found in Dmanisi, Georgia. The species had a small stature and brain size similar to earlier African species, with some modern aspects of lower limb morphology.
As personal genomics advances, researchers caution against mass adoption due to ethical, social, and clinical concerns. The integration of genome sequences into routine clinical care poses significant challenges for healthcare systems.
Researchers at UCSD School of Medicine have solved the structure of protein kinase A, a key enzyme involved in memory formation, nerve cell communication, and cardiac function. The study reveals how PKA is inhibited and activated by cyclic AMP, shedding light on its role in cardiac disease and breast cancer.
Researchers discovered that material in the lower mantle behaves differently than predicted by models, indicating a continuous spin-transition zone from 620 to 1,365 miles deep. This finding calls into question traditional techniques for modeling this region of the planet and may explain some experimental findings.
A new study from the University of Michigan Comprehensive Cancer Center finds that cancer patients and their spouses experience similar physical and emotional quality of life. The study, which analyzed data from 263 men with prostate cancer and their spouses, found significant differences in quality of life based on the phase of illness.
Researchers have identified a pattern of fetal mRNAs detectable in pregnant women's blood, which could serve as a baseline for diagnosing genetic diseases. This detection method has the potential to replace invasive prenatal procedures, offering a new approach to monitoring fetal health.
Researchers have developed a new non-invasive prenatal testing method that analyzes mother's blood to detect fetal mRNAs, which could be used for prenatal diagnosis of genetic diseases. In another study, mice exposed to particulate matter were found to have accelerated blood clotting and thrombosis, highlighting the need to target IL-6...
Scientists have located the spin transition zone of iron in Earth's lower mantle, a discovery that could improve our understanding of the planet's structure, composition, and dynamics. The study used advanced techniques to probe the electronic spin state of iron under high pressure-temperature conditions.
Researchers investigating statin effects on heart cells hope to understand disease process better and develop new treatments. The study, led by Dr Sarah Calaghan at the University of Leeds, aims to determine how statins affect caveolae and impact heart behavior.
New research from Northwestern University's Feinberg School of Medicine identifies how microscopic air pollution kills people at risk. The study found that lungs inflamed by the pollution secrete a substance that causes blood to clot, raising the risk of fatal heart attacks or strokes.
Dr. Rajarathnam Chandramouli is leading a three-year project grant to research and develop software defined radio-based cognitive radio technologies for public safety radios to optimize spectral efficiency. The proposed protocols aim to create broadband connections for quality of service in public safety bands.
The Preserving Virtual Worlds project aims to develop standards for preserving digital games and interactive fiction like Second Life. The project will explore methods, infrastructure, and technology for preserving complex software, content, and interactivity in computer games and electronic literature.
A study by Tufts University physicist Roger Tobin suggests that steroid use can increase home run production by 50-100% through a 4% increase in batted ball speed. Muscle mass boosts also contribute to higher bat and ball speeds, leading to more dramatic effects on home runs.
A single dose of tolvaptan significantly increased urine volume and reduced pulmonary artery pressure, with more pronounced effects at higher doses. The study found no significant differences in cardiac output or other secondary outcomes.
A new study used gene chip data to improve treatment outcomes for patients with advanced, incurable cancer. Four out of seven patients showed a better response than expected when their tumor's gene expression was analyzed and used to guide treatment.
New chemotherapy regimens such as irinotecan and oxaliplatin-based treatments have been shown to prolong the survival of patients with advanced colorectal cancer. The meta-analysis found that these regimens can provide an estimated absolute survival benefit of 8-4.7 months for certain patient groups.
Children's Hospital of Pittsburgh psychiatrist Eva Szigethy has been awarded a prestigious NIH grant to study the interactions between the brain, gut, and immune system in adolescents with chronic disease. Her research aims to improve early identification and treatment of depression in children with IBD.
A study published in the Journal of Pediatrics found that parents who feel confident communicating with physicians are more likely to participate in medical decisions. Researchers also discovered that previously hospitalized parents are more involved in decision-making.
Scientists have successfully reprogrammed adult stem cells from male mice' testes into functional blood vessels and cardiac tissue. These multipotent adult spermatogonial-derived stem cells may offer an alternative to embryonic stem cells without ethical concerns.
A team of Brown University biomedical engineers has invented a 3-D Petri dish that can grow cells in three dimensions, enabling the quick and cheap production of realistic cells for drug development and tissue transplantation. The technique employs a new dish made from a sugary substance that allows cells to self-assemble naturally and...
Researchers at MIT have created an exoskeleton device to lighten the burden of heavy backpacks, transferring weight to the ground. The prototype successfully takes on 80% of an 80-pound load but impairs natural walking gait.
Researchers discovered that nerve growth factor (NGF) is positively related with liver cancer, the No.2 killer among all kinds of cancers. NGF and its receptor trkANGF were expressed in liver cells of patients with liver cirrhosis and/or hepatocellular carcinoma.
A study found that childhood vaccination for the rubella virus may have eliminated an inflammatory eye disease from the U.S.-born population. The vaccine was implemented in 1969, and subsequent reductions in Fuchs heterochromic iridocyclitis (FHI) cases were observed, especially among foreign-born patients.
Researchers at Hebrew SeniorLife's Institute for Aging Research have examined nearly 100,000 genetic markers to determine which genes are responsible for osteoporosis and longevity. The studies found associations between specific genetic variants and traits such as bone mineral density and age at death.
Research reveals that subtle racism is more damaging than overt hostility, impairing cognitive capacity and mental effort. Black volunteers who witnessed unfair but ambiguous hiring decisions performed worse on the Stroop test, indicating they were using all their mental resources to make sense of the unfairness.
Researchers have used NASA's SeaWiFS instrument to study ocean biological productivity and its connection to climate change, providing insights into the health of the oceans. The data has applications for setting pollution standards, sustaining coastal economies, and predicting future ocean health.
Researchers from Weill Cornell Medical College report a breakthrough in isolating specialized subsets of spermatogonial stem cells that can generate a wide range of cell and tissue types. The study's findings have promising implications for regenerative medicine, offering an alternative to embryonic stem cells.
A multi-center study found that repeated courses of steroids given to premature babies may increase the risk of cerebral palsy. The study, led by Dr. Ronald Wapner, followed 556 infants and found that six out of 248 who received multiple steroid courses had been diagnosed with cerebral palsy.
A recent study suggests that an abnormal amount of inflammatory cells in the duodenum may be responsible for nonulcer dyspepsia, a condition characterized by chronic or recurrent abdominal pain. The researchers propose targeted anti-inflammatory medicine as a potential treatment option.
A Review in The Lancet emphasizes the importance of a healthy lifestyle in reducing stress to manage risk factors associated with adverse cardiovascular outcomes. Studies have shown that both acute and chronic stressors can increase the risk of cardiac events, with major life changes and emotional stressors being key contributors.
A new study by University at Buffalo researchers found that extreme cherry pickers barely affected retailer profits, with only 1.2% of grocery store customers engaged in this behavior. These 'extreme' shoppers saved an average of 76% of potential savings through their shopping strategies.
A RAND Corporation study suggests that unofficial diplomatic discussions, known as Track Two diplomacy, can have a positive effect on shaping attitudes in the Middle East and South Asia. These long-term strategies focus on socialization and generating new ideas, rather than immediate policy change.
A study found that Dutch GPs unnecessarily prescribe antibiotics for respiratory tract infections based on arbitrary diagnostic labelling and patient symptoms. The over-prescription of antibiotics poses significant risks due to resistance and costs.
A new study reveals firefly flash signals are energetically cheap but more conspicuous flashes increase predation risk. This balancing act could generate new firefly species with unique flash codes.
A six-year study involving 3,885 participants found no significant changes in memory function among overweight and obese individuals. In contrast, those who were underweight experienced more cognitive decline over time. The study suggests that being overweight or obese in old age may not be a risk factor for memory problems.
A study of HIV-infected women found that pregnancy can actually slow disease progression, not accelerate it. The use of HAART during pregnancy significantly reduces the risk of transmitting the virus to the child, and pregnant women tend to have lower risks of disease progression before and after pregnancy.
Researchers from Boston University and NHLBI analyzed genetic differences associated with cardiovascular disease and other disorders using Framingham Heart Study data. The study found associations between specific genomic regions and characteristics such as blood pressure, lipids, and diabetes.
A three-year study published in the Proceedings of the National Academy of Sciences found that an increase in mercury loading resulted in a significant increase in methylmercury production and accumulation in fish. The study suggests that reducing atmospheric mercury emissions can lead to lower mercury levels in fish within a few years.
A team of researchers has identified the region in the brain responsible for perceiving sound space. The study used an improved experimental design to map the auditory spatial location center and found that the planum temporale is activated when people locate sounds in space, indicating a nonintentional representation of spatial location.
Gynecomastia, benign enlargement of male breast tissue, affects 40-50% of males at some point in their lives. The condition can be treated with medication or surgery, and awareness is key to correct diagnosis and reassurance for affected men.
A study analyzing sediments from a British bog found that methane emissions increased due to intense global warming around 55 million years ago. The team discovered that carbon isotope values of hopanoids suddenly decreased, indicating a shift in the diet of bacteria from carbon-based compounds to methane.
Argon atoms are found to be tenaciously bound in the Earth's mantle and move slowly, contradicting widely held theories. This suggests that early degassing was incomplete and primordial gases still remain trapped at great depth.
New research supports the cardiovascular safety of ACTOS (pioglitazone HCI) and its benefits in improving blood glucose and lipid levels. The study found that therapies including pioglitazone are associated with significant reductions in the risk of stroke or myocardial infarction compared to non-thiazolidinedione therapies.
A study suggests that teenage girls' friendships play a crucial role in protecting them from abuse in dating relationships. The 'circle' of friends sets social norms and values, acts as a safety net, and helps girls navigate uncertain situations. Strong friendship circles reduce uncertainty and protect against abuse.
Researchers have identified the specific gene implicated in Job's syndrome, a rare immunodeficiency disorder characterized by harmful bacterial and fungal infections. The discovery could benefit treatment for other immunodeficiency diseases and provide new leads for therapies.
A team of scientists warns that CO2 emissions could alter ocean chemistry, violating EPA water quality criteria by mid-century. The study predicts that atmospheric CO2 concentrations will exceed 500 ppm by century's end, posing significant risks to marine biota and food webs.
A new method using microwaves can determine the fat content of beef and other meat products, offering a fast and non-invasive alternative to current methods. The technology has potential to reduce waste, save energy, and improve food safety in the industry.
A new study found that individuals with a family history of alcoholism are more likely to reduce their drinking when prescribed naltrexone. However, those without a family history of alcoholism may experience increased drinking with higher doses of naltrexone.
Scientists at the Smithsonian Tropical Research Institute have discovered an established population of invasive Harris mud crabs in the Panama Canal's Miraflores Third Lock Lake. The crustaceans, native to North America, are known to cause environmental and economic harm, fouling pipes and preying on fish in gill nets.
The University of Manchester is leading UK involvement in the £1.1 billion Square Kilometre Array project, which will create a detailed map of the sky and allow astronomers to test Einstein's theory of relativity and search for signs of alien life.
A global study has found that phosgene is present in all latitudes and its levels have decreased since previous studies. The gas plays a role in pharmaceuticals, herbicides, and synthetic materials, but its use is being reduced due to legal restrictions.
A new study found that irregular Pap smears and false negative tests were not the primary reasons for cervical cancer development. Instead, socio-economic disparities in screening access may be a major obstacle to eradicating the disease.
Researchers distinguish brain circuitry for surprise and aversive stimuli, finding different neuronal populations respond to expectation of reward or punishment. This study sheds light on the amygdala's role in emotion, reinforcement learning, attention, and arousal.
Researchers found that certain cancer treatments can increase the expression of Nanog and BMI1 stem cell markers in cancer cells, allowing them to survive treatment and potentially leading to tumor growth. Understanding these pathways could lead to the development of new therapeutic targets.
A molecular recycling plant has been found in the brain that enables nerve cells to record new experiences and maintain memories over time. This process involves the constant movement of receptors around synapses, which are then recycled and returned intact.
Researchers found that 60% of staff suffered from anxiety, but this fell to just 8% after aromatherapy massages and relaxing music. The study also examined seasonal differences and found a greater reduction in winter months.