A new Alzheimer's treatment, CTS-21166, designed by a Purdue University researcher has begun human clinical trials. The experimental drug is a disease-modifying therapy that could prevent and reverse the disease by intercepting and disabling key enzymes.
Researchers have made progress in treating neuroblastoma, a difficult pediatric cancer, with new approaches such as radioactive isotopes and targeted therapies. However, further understanding of the disease's precise biology is needed to guide optimal treatment choices.
A novel gene therapy technique has been found safe and effective in reducing worsening symptoms of Parkinson's disease in advanced patients. The treatment, which involves injecting genes into one side of the brain to restore a critical neurotransmitter called GABA, showed a 27% improvement in symptoms among participants.
Researchers at Goethe University Frankfurt have identified a novel Ub conjugation reaction that allows for more efficient manipulation of key proteins in the treatment of cancer and other diseases. This discovery provides a basis for novel therapeutic approaches that are more specific than existing drugs like Bortezomib.
Two MSU professors, Volodymyr Tarabara and Tom Voice, are leading an international partnership to create new water purifying strategies using membrane-based technologies. The project aims to develop more efficient membranes that can produce ultrapure water, improving public health in developing countries.
Researchers at Brown University have developed a technique to synthesize iron-platinum nanorods and nanowires with controlled size, composition, and magnetic alignment. The method produces batches of similarly-sized nanowires or rods in solution, showing promise for high-density information storage and other applications.
The BBVA Foundation has awarded six Biomedicine Chairs to leading international specialists, facilitating collaboration between Spanish and international researchers on basic research in hepatic diseases, cardiovascular diseases, and cancer. The chairs also support clinical research in craneoencephalic trauma rehabilitation and the dev...
Researchers have developed multifunctional nanoparticles that target and image cancer cells by exploiting overexpression of folic acid receptors. These dendrimer-based systems can accumulate in diseased cells and retain bright fluorescence, allowing for easy visualization via confocal microscopy.
Researchers at St. Jude Children's Research Hospital discovered how a single molecular switch triggers gene activity, affecting learning, memory and glucose production in the liver. The study shows that genes choose their co-factors, requiring a more complex view of CREB's function.
The BBVA Foundation is funding 12 research projects in Ecology and Conservation Biology, focusing on climate change's impact on shorebird populations and mercury pollution in biodiversity hotspots. The projects also include studies on noise pollution's effect on tropical birds and the conservation status of the monito del monte marsupial.
A study predicts that using Tamiflu prophylactically could reduce illness and death rates during an influenza pandemic by half, with a cost savings of $70,000 per 1,000 population. Prophylaxis with antivirals or vaccines is considered a crucial strategy in the early months of a pandemic.
The University of Georgia is partnering with Mexican universities to develop innovative technologies for generating biofuels from agricultural waste. This initiative aims to support rural economic development and environmental sustainability by providing training, internships, and exchanges between UGA and Mexican academics and profess...
Researchers have discovered a new compound called AN2690 that effectively treats fungal infections by blocking protein synthesis. This breakthrough could lead to the development of new antibacterial compounds to combat antibiotic resistance.
A new study found that software enhancement of breast MRI scans reduces false positive identifications by 23 percent, improving the accuracy of radiologists. The software analyzes multiple imaging series to provide detailed data on lesion morphology and kinetic features.
The American Thoracic Society has published a new statement on pulmonary function testing in preschool children, addressing clinical, technical, and epidemiological implications. The guidelines focus on spirometry and other techniques to evaluate lung function in this age group.
A new study has identified proteins in the rod and cones of the eye that could lead to the discovery of the genetic causes of a host of inherited eye diseases. The researchers hope to gain a clearer understanding of what goes wrong at the most basic level in these diseases that cause blindness and other disorders.
Researchers warn of vulnerability to satellite attacks due to low technical barriers, threatening global positioning systems, weather satellites, and more. With a college-level team and intermediate-range missiles, amateurish yet effective attacks can be launched.
A new vaccine has been developed to prevent hCMV infection and disease in mice, showing promise for human use. The vaccine generates an immune response that protects against both infection and disease by disarming the virus's ability to replicate.
The International Association of National Public Health Institutes (IANPHI) has awarded short- and mid-term technical assistance grants to public health institutes in five nations. The grants aim to support the development of national public health institutes and improve service delivery and decision-making globally.
Researchers established a credible scientific method for testing and measuring xanthones in whole mangosteen fruit, which shows high xanthone absorption when using the entire fruit as a delivery vehicle. This study ensures consistent and reliable marketing of mangosteen products to consumers relative to claims of xanthone content.
Nicholas Tan Xue-Wei, an 18-year-old Singaporean student, will present his research paper on stem cells at two international conferences in the US and UK. He was nominated for a Best Paper Award at WCE 2007 for his work on growing Mesenchymal Stem Cells in a serum-free medium.